Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Clarifying variables, data presentation, tables, Frequency distribution drawings charts and diagrams.
Measures of central tendency and location, Mean, median, mode, position average, and percentile.
Measures of dispersion, Range, inter-quartile range, mean deviation, standard deviation and
coefficient of variation.
7. Probability: Probability scale, measurement of probability, laws of probability for independent
events, conditional probability, Bayes theorm. Additional law of probability, Multiplication law of
probability, Probability distribution, Probability chance from shape of normal distribution or normal
curve, binomial distribution, Poisson distribution, normal distribution, Standard normal deviate,
Asymmetrical distribution, t distribution.
8. Statistical sampling, Population, sample, sampling variations and bias, probability sampling methods,
Simple random sampling, Systematic random sampling, Stratified random sampling, Multistage
sampling, Multiphase sampling, Cluster sampling, Advantages and disadvantages of different types of
sampling, Appropriate use of different types of sampling, Non probability sampling methods, Sample
size, Concepts in calculation of sample size.
9. Evaluating role of chance, Normal distribution, inferential statistics, hypothesis testing, p value,
confidence intervals. Confidence interval for mean, statistical test of significance for difference
between two means and more than two means (ANOVA). Confidence interval for proportion,
statistical test of significance for difference between two proportions and more than two
proportions (chi-squared test).
10. Correlation, Correlation coefficient, Positive correlation, Negative correlation, Rank correlation,
linear regression, Simple and multiple regression and logistic regression. Non parametric methods,
Sign test, Wilcoxon signed-rank test, median test, Mann-Whitney test, Kruskal-Wallis test, Friedman
test, Spearman rank correlation coefficient. Advantages of non-parametric methods over parametric
methods, disadvantages of non-parametric methods over parametric methods, and applications of
non- parametric tests.
11. Ethics and biomedical research: General principles on ethical considerations involving human
subjects, ethical review procedures, Institutional ethics committee, its organization and functions,
general ethical issues. Specific principles for clinical evaluation of drugs / devices / diagnosis
vaccines / herbal remedies, specific principles in epidemiological studies, specific principles in human
genetic research, specific principles for research in transplantation including fetal tissue
implantation, Publication ethics.
12. Ethical guidelines for experimental animals: Sources of experimental animals, Lab. Animal husbandry
and management, anesthesia and euthanasia, laboratory animal ethics, institutional animal ethics
committee, its organization and functions and responsibilities, ethical guidelines for use of animals
for scientific research, The 3 Rs (Replacement, Reduction, Refinement), CPCSEA guidelines, Ethical
principles adopted by CPCSEA for use of animals in scientific experimentation, in-vitro system to
replace animals, legal provisions for experimentation of animals.
Reference books:
1. Epidemiology in medicine, Charles H. Hennekens and Jules E.Burling.(1987)
2. Oxford Text Book of Public Health (5th edition), volume 2, Oxford University press.(2011)
3. Essentials of Medical Statistics by Belty R. Kirkwood.(2011)
4. An Introduction to biostatistics by P.S.S. Sundar Rau.(2006)
5. Ethical guidelines for biomedical research on human subjects, ICMR, New Delhi 2006
6. Guidelines for care and use of animals in scientific research. Indian National Science
Academy, New Delhi 2000.
7. Research Methodology, methods and techniques by C.R. Kothari.(2009)
8. Basic epidemiology, 2nd edition, R Bonita, R Beaglehole and T Kjellstrom (2007)
9. Statistical methods in medical research, 4th edition, P Armitage, G Berry and JNS Matthews.
(2001)
10. Biostatistics: A foundation for analysis in health sciences, 9th edition, Wayne W Daniel 2008
12. Epidemiology of communicable diseases and prevention & control, modes of transmission of
diseases, disinfection, levels of prevention and modes of intervention of diseases, epidemiology
of non-communicable diseases and prevention & control, concept of screening for disease and
screening tests, occupational hazards, ESI, social security, principles of communication and
health education, primary health care, universal health coverage, health care delivery, National
health programs, fertility rates, demography & family planning, environment & health.
Recommended books
Davidsons Principles and Practice of Medicine.
Guyton & Hall Textbook of Medical Physiology
Harpers Biochemistry
Pharmacology by Rang & Dale
Textbook of Microbiology by Ananthanarayanan & Jeyaram Panicker
Achars textbook of Pediatrics
Clinical Obstetrics by Mudaliar & Menons
Parks Textbook of Preventive and Social Medicine by K Park
Parsons Diseases of the Eye
Textbook of Ear,Nose & Throat Diseases by Mohd. Maqbool
8. Maxillary Sinus:
9. Saliva:
10. Calcium, Phosphorous & fluoride metabolism:
11. Physiology of Taste:
Unit 4
(A)
1. Cell Injury&change
2. Cell death & Necrosis
3. Inflammation
4. Healing
5. Ischaemia and infraction
6. Derangements of body fluids
7. Disorders of circulation
8. Cancer
9. Anaemias&leukaemias
10. Common diseases of Bones
11. Haemorrhagic Disorders
(B)
1.
2.
3.
4.
Unit 5
1. General principles of pharmacology; pharmacokinetics
2. CNS drugs, Autonomic drugs; Cardiovascular drugs ,Gastrointestinal tract
drugs,hormones,chemotherapy - Implications of these drugs in clinical dentistry.
3. Autocoids:Histamine, antihistamines, prostaglandins, leukotriens,
4. Drugs acting on blood: coagulants and anticoagulants, hematinics, Implications of
these drugs in clinical dentistry.
5. Vitamins: water soluble vitamins, Vito D, Vit K. and Vit E, Implications, of
Vitamins in clinical dentistry.
6. Anti-septics, astringents, obtundents, mummifying agents, bleaching agents,
styptics, disclosing agents, dentifrices, mouth washes, caries and fluorides.
Unit 6
1. A bird's eye view of the different pathological processes involving the oral cavity &
oral cavity involvement in systemic diseases
2. Developmental disturbances of teeth, jaws and soft tissues of oral ¶oral
region:
3. Microbial infections of oral soft tissues:
4. Common non- inflammatory diseases involving the jaws
5. Cysts of the Oral & Para oral region:
6. Tumours of the Oral Cavity:
7. Traumatic, Reactive & Regressive lesions of Oral Cavity:
8. Non neoplastic Salivary Gland Diseases:
9. Systemic Diseases involving Oral cavity:
10. MucocutaneousLesions :
11. Diseases of the Nerves:
12. Pigmentation of Oral &Paraoral region &Discolouration of teeth:
Unit 7
1. Dental caries:
2. Treatment Planning For Operative Dentistry: gnathological Concepts Of
Restoration:
3. Physiology of occlusal rehabilitation and restoration.
4. Amalgam Restoration:
5. Pulp Protection:
6. Anterior Restoration;
7. Direct Filling Gold Restorations:
8. Hyper Sensitive Dental And Its Management.
9. Cast Restorations
10. Vitality tests, Diagnosis and Treatment Planning and Preparation of Case Sheet.
11. Dental porcelain
12. Aesthetic Dentistry
13. Endodontics
Unit 8
1. Principles of infection control and cross-infection control
2. Principles of Oral Surgery
3. Asepsis:
4. Sterilisation of instruments
5. Exodontia:
6. Diseases of the maxillary sinus
7. Disorders of T.M.Joint
8. Infections of the Oral cavity
9. Benign cystic lesions of the jaws
10. Tumours of the Oral cavity
11. Fractures of the jaws
12. Salivary gland diseases
13. Jaw deformities14. Oral Implantology
15. Local anaesthesia
16. General anaesthesia
Unit 9
1. Teeth: Development abnormalities, causes of destruction of teeth and their sequelae
and discoloration of teeth.
2. Disease of bone and Osteodystrophies
3. Common cysts of soft tissue &bone . 4.Tumours
4. Infections of oral and paraoral structures:Bacterial: Fungal; Candida albicansVirus:
5. Important common mucosal lesions
6. Cervico-facial lymphadenopathy
7. Facial pain:
8. Altered sensations: Cacogeusia, halitosis
9. Tounge in local and systemic disorders:
10. Oral manifestations of systemic diseases
11. Disease of salivary glands:
12. Dermatological diseases with oral manifestations:
13. Allergy:
14. Foci of oral infection and their ill effects on general health
15. Management of dental problems in medically compromisedpersons:
16. Precancerous lesions
17. Nerve and muscle diseases:
18. Therapeutics: Gene
19. Drugscommonly used in oral medicine
20. Physics of radiation: Biological effects of radiation
Unit 10
1. Growth and Development
2. Morphologic Development of Craniofacial Structures
3. Functional Development of Dental Arches and Occlusion
4. Clinical Application of Growth and Development
5. Malocclusion-InGeneral
6. Classification of Malocclusion
7. Normal and Abnormal Function of Stomatognathic System
8. Etiology of Malocclusion
9. Diagnosis and Diagnostic Aids
10. Removable orthodontic appliances
11. Fixed orthodontic appliances
RECOMMENCED BOOKS:
1. RJ LASTS Anatomy - McMinn, 9th edition
2. Guyton; Text book of Physiology, 9th edition.
3. Harper's Biochemistry, 1996., R.K. Murrayet.al.
4. Robbins Text Book Of Pathology -Kumar
5. Text book of Microbiology - R.Ananthanarayan&C.K.JayaramPaniker
6. Tripathi K.D., Essentials of Medical Pharmacology
7. Orban's Oral Histology & Embryology - S.N.Bhaskar
8. Glickmans Clinical Periodontoloy Carranza
9. Davidsons Text book of Medicine
10. Bailey & Love - General surgery
11. Burkitt Oral medicine
12. A Text Book of Oral Pathology - Shafer, Hine & Levy.
13. Contemporary orthodontics
William R. Proffit
14. Textbook of Pedodontics- ShobhaTandon
15. Bouchers Prosthodontic treatment for edentulous patients
16. Principles of oral and maxillofacial surgery; vol.1,.2, 3 Peterson LJ et al
5. Drugs and Cosmetics Act 1940 and Rules 1945, Drugs Prices Control order, Patents Act
1970, Pharma marketing, elements of market research, materials and production
management, GMP, GLP, Quality assurance, TQM, validation - equipment, process and
analytical methods, basics of drug regulatory affairs.
6. Methods of preparation, uses, sources of impurity, tests for purity and limit tests for the
following classes of inorganic pharmaceuticals of Indian Pharmacopoeia: Gastrointestinal
agents, electrolytes, essential and trace elements, topical agents, oxygen, anaesthetics,
dental products, buffers and radiopharmaceuticals. Fundamentals of physical chemistry
of importance to pharmacy Kinetic theory of gases, colligative properties, partition
coefficient,
thermochemical
equations,
photochemistry,
chemical
kinetics,
thermodynamics and quantum mechanics.
7. Fundamentals of organic chemistry of importance to pharmacy: Atomic structure, orbital
theory, wave equation, types of orbitals and bonds, polarity of molecules, intermolecular
forces, acids and bases, isomerism and stereo isomerism, stereo specific reactions,
nucleophilic and electrophilic addition and aromatic substitution reactions, elimination
reactions and neighboring group effects.
8. Bioenergetics and ATP production, enzymes, co-enzymes, iso-enzymes and co-factors.
Carbohydrate and lipid metabolism, citric acid cycle, biological oxidation, metabolism of
ammonia and nitrogen containing monomers, formation of deoxy ribonucleotides, purine,
pyrimidine and nucleic acid biosynthesis, mutation, genetic code and protein synthesis.
9. Methods of synthesis, physico chemical properties, mode of action and structure activity
relationships of the following classes of drugs: Cholinergics, anti-cholinergics and
cholinesterase inhibitors, adrenergics, antispasmodics, anti ulcer drugs, local anaesthetics,
neuromuscular blocking agents, autocoids, steroids, diuretics, cardiovascular drugs,
thyroid and anti thyroid drugs, insulin and oral hypoglycemic agents, CNS drugs, antimetabolites, anti-neoplastic agents, anti-viral agents, immunosuppressives, diagnostic
agenst and pharmaceutical agents. Bio isosterism, drug-receptor interactions, drug
metabolism, pro-drug concept, Approaches to drug design analog based, mechanism
based and QSAR based. Computer aided drug design and molecular modeling.
10. Types of errors, statistical treatment of data, precision and accuracy, fundamentals of
volumetric analysis, acid-base titrations, oxidation-reduction titrations, precipitation
titrations, gravimetric analysis, non-aqueous titrations, complexometric and diazotization
titrations. Potentiometry, conductometry, coulometry, polarography, amperometry,
gasometry and chromatography. Principles, instrumentation and applications of UV-VIS,
IR, NMR and Mass spectrophotometry, flame photometry, flourimetry, atomic absorption
spectroscopy, x-ray diffraction analysis and radio immunoassay.
Books recommended
1. The Science and Practice of Pharmacy by Remington
2. Bentley and Drivers Text Book of Pharmaceutical Chemistry by Atherden L M
Reference books
1.
2.
3.
4.
5.
6.
7.
8.
3.
4.
5.
8.
9.
Nursing management of patient in critical care units: Nursing assessmenthistory and Physical assessment, Classification, Principles of critical care nursing,
Organization: Physical setup, Policies, staffing norms, protocols, equipment and
supplies, special equipments: ventilators, cardiac monitors, defibrillators,
Resuscitation equipments, Nursing management of critically ill patient, CPR
Advance Cardiac Life support, Treatments and procedures
10. Nursing care of a normal neonate, Neonatal resuscitation, Low birth weight
affective disorder, Mania depression and dysthymia: neurotic, stress related and
somatization disorders: Anxiety disorder, Phobias, Dissociation and conversion
disorder, Obsessive compulsive disorder, somatoform disorders, post traumatic
stress disorder, substance use disorders, mental retardation
12. Assessment and nursing management of normal pregnancy, labour and
Unit I:
1. Divisions and functions of the nervous system, nerve fibres and synapse
2. Structure of brain and its divisions, planes
3. Cerebrum, lobes of the brain, structures and functions
4. Cerebellum, neurotransmitters
5. Brainstem and cranial nerves origin and insertion
6. CSF secretion, absorption, pathway and its composition
7. Blood supply to central nervous system, blood brain barrier, circle of Willis
8. Neuromuscular junction
9. Broadmanns area, motor and sensory homunculus
10. Spinal cord, reflex arc
Unit II:
1. Cells, tissues and cartilages of head and neck
2. Muscles of neck and face An introduction Muscles of lips, cheek, and muscles of
mastication, physiology of swallow
3. Muscles of tongue Intrinsic and extrinsic muscles origin, insertion, functions
and nerve innervations
4. Muscles of palate, origin, insertion and nerve innervations ,muscles of pharynx,
Velo-pharyngeal mechanism and function
5. larynx, cartilages (paired and unpaired), connections and nerve innervations, vocal
fold physiology
6. Para nasal sinuses (frontal, maxillary, ethmoidal and sphenoidal),blood supply,
venous drainage of head and neck
7. Anatomy of ear, parts of external, middle and inner ear, blood supply, venous
drainage and nerve supply
8. Physiology of hearing and balance
9. Anatomy of eye, gland, blood supply and optic nerve, eye function
10. Anatomy of tooth, types of teeth, parts of tooth, structure, arterial supply and
lymphatc drainage
Unit III:
1. Introduction to Myology Types of muscle tissues
2. Introduction to skeletal muscles General functions, muscle contraction and
relaxation
3. Muscle tone, strength and conditioning
4. Brief anatomy of heart, chambers of heart
5. Cardiac cycle
6. Blood vessels, blood composition
Unit VII:
1. Definition of psychology, historical development, modern history of clinical
development
2. Scope of clinical psychology in health science
3. Concepts of normality and abnormality
4. Methodology in clinical psychology (case history, interview and observation)
5. Psychology of learning (classical and operant conditioning), reinforcement and
strategies
6. Piagets theory of cognitive development and Sigmund Freuds theory of
psychosexual development
7. DSM and ICD classification of abnormal behaviour
8. Assessment of Primary mental function Attention, concentration, memory,
intelligence (verbal and non verbal)
9. Assessment of personality and interpersonal relationship
10. Introduction to cognitive behaviour therapy and counselling
Unit VIII:
1. Introduction to food, nutrition and health. Definition of nutrition, health, good
nutrition and Malnutrition
2. Diet and health: Problems of deficiency, disease of affluence, food safety: addictives
and contaminants
3. Digestion and absorption of Carbohydrates, fats, proteins, vitamins and iron
4. Overweight and obesity: Cause and treatment
5. Nutrition and dietary consideration at different stages of life
6. Nutrition in deficiency and diet related diseases
7. Water and electrolyte balance
8. Food security, organic foods and technologies for food and nutrition security
9. Nutrition and health significance of food ingredients
10. Nutritional implications of food processing and packing
Unit IX:
1. Introduction to counselling, definition, scope of counselling practise, origin and
history of counselling
2. Phases of counselling assessment, initiation and termination
3. Different facets of counselling: Individual and group counselling, skills in
counselling observation, questioning,, communication, making notes and
reflections
4. Hospital counselling: Counselling to terminally ill, pain management,
rehabilitation counselling in hospitals
5. Cultural issues in counselling
6. Counselling intellectual exceptionality superior and mental retardation
7. Counselling sensory handicaps visual, hearing, speech, motor
8. Family, personal and educational counselling
9. Ethical codes & guidelines right of clients, dimensions of confidentiality
10. Ethical and legal responsibilities
Unit X:
1. Current electricity, static electricity, voltage, current, resistance, effects of electricity
on human body (electric shock), causes, precautions
2. Basic electronics, conductors, insulators, semiconductors, passive circuit devices,
diodes, transistors, voltage stabilizers.
3. Amplifiers and oscillators, classifications, types, working principles, applications.
4. Transducers, microphones, bio-sensors, piezo-electric transducers, construction,
working and uses
5. Measuring instruments, multimeter, cathode ray oscilloscope, sound level meter,
integrated sound level meter, audio frequency oscillator
6. Sound , production and propagation of sound, transmission of sound, reflection,
diffraction, interference, application of sound
7. Light, nature of light, reflection, refraction, defects of vision and correction
8. Heat, nature of heat, types of heat transfer, regulation of body temperature and
applications
9. Electromagnetism in diagnosis, Magnetism and electricity, basic procedures
involved in ECG, EEG, EMG, EGG, CT, MRI
10. Electronic equipment in patient care, use and precautions
References:
A Agarwal & S Udipi. Textbook of human nutrition. 2014. Jaypee brothers medical
publishers ltd. New Delhi.
A Parthasarathy. IAP textbook of paediatrics. 3rd Ed. 2006. Jaypee brothers medical
publishers ltd. New Delhi.
CT Morgan, RA King, JR Weisz & J Schopler. Introduction to psychology. 7th ed. 2008. Tata
McGraw Hill. New Delhi
DA Bender. Introduction to nutrition and metabolism, 2nd ed. 2002. London.
JD DiClementi, IG Sarason & BR Sarason. Abnormal Psychology, The Problem of Maladaptive
behaviour 11th Ed. 2004, Pearson/Prentice Hall. New York
K Thayalan. Bio-medical physics. 2007. Jaypee brothers medical publishers Ltd. New Delhi.
KT Patton, GA Thibodeau & MM Douglas. Essentials of anatomy and physiology. 2011.
Elseiver Health Sciences Division. NY.
LB Jorde, JC Carey & MJ Bamshad. Medical genetics 4th ed. 2010. Mosby Inc. PA
R Soundararajan. Counselling- theory, skills and practice. 2012. Tata McGraw Hill Education
Pvt. Ltd. New Delhi.
RW Dudek & JD Fix. Embryology. 3rd ed. 2005. Lippincott William & Wilkins Ltd. PA
V Kumar, AK Abas & JC Aster. Robbins basic pathology, 7th Ed. 2013. Elsevier Saunders.
Canada
V Singh. Anatomy of head neck and brain Vol 3. 2nd Ed. 2014. Reed Elsevier India Pvt Ltd.
New Delhi.
V Singh. Anatomy of upper limb and thorax Vol 1. 2nd Ed. 2014. Reed Elsevier India Pvt Ltd.
New Delhi.
VK Mehta, R Mehta. Principles of electronics. 2005. S Chand & Company Ltd. New Delhi.
Unit 2: Digestion, bioenergetics, biological oxidation and reduction, enzymes and coenzymes,
enzyme kinetics, carbohydrate metabolism, lipid metabolism, amino acid and protein metabolism,
nucleic acid & nucleotide metabolism and the urea cycle, the citric acid cycle (Krebs cycle / TCA
cycle), vitamins and minerals, electron transport and oxidative phosphorylation.
Unit 3: Gene bank databases, structure databases, genomic mapping, sequence search databases,
multiple protein sequences and their alignment, predictive modeling and comparative genome
analysis.
Unit 4: Cellular organization, cell divisions, cell cycle, cell organelles, cytoskeleton and cell
signaling & signal transduction.
Unit 5: Gametes and gametogenesis, Fertilization and zygote formation, Early development and
germ layers, Organogenesis
Unit 6: Ecosystem, biomes, ecological niche, mineral and other hydro-geological cycles, trophic
levels, threats to the environment, environmental protection and conservation.
Unit 7: Mendelian and non-Mendelian inheritances, nucleic acids, DNA replication, RNA
transcription, central dogma genetic code/translation, DNA condensation and structural
organization, regulation of gene expression, mutations and DNA repair mechanisms and rDNA and
genetic engineering.
Unit 8: Innate Immune System, Adaptive Immune System, Antigens, Antibodies, Humoral and
Cell Mediated Immune Mechanisms, Antigen-Antibody Interactions, Immunoglobulin Genes,
Major Histocompatibility Complex, Antigen Processing and Presentation, Cytokines, Complement
System, Vaccines, Transplantation Immunology and Antibody Engineering
Unit 10: Microbial structure and function microbial growth and metabolism prokaryotic genetics
microbial infection and diseases and microbial control.
Unit 11: Classification and phylogeny, evolution, levels of organization, tissue and organ systems,
animal physiology, concepts of regeneration and reproduction.
Unit 12: Classification and phylogeny, evolution, plant anatomy, reproduction, photosynthesis light and dark reactions (Calvin cycle), respiration and photorespiration, phytohormones and
phytochemicals.
Reference books*
*These books are only suggestive and do not comprehensively cover all the units
included in the syllabus. This is due to the broad nature of the syllabus and the
limitation of many textbooks in dealing only with a specific topic of life sciences. It is
recommended that the candidates refer to books and reading material that are not
limited to this list of references, but will cover all the units of the syllabus individually.
1. Principles of Biochemistry - Lehninger
2. Introduction to Bioinformatics - Arthur M. Lesk
3. Genes VIII - Lewin
4. Kuby Immunology - RA Goldsby, Thomas J, Kindt
5. Cell and Molecular Biology - E.D.P . De Robertis and E.M.F. De Robertis Jr. &
Febiger
6. Microbiology - Prescott & Harley, Madigan & Martinko
7. Biology- Campbell
appraising performance, Types of Appraisal Interviews, 360 Degree Feedback, Balanced Score
Card, Career Planning and Development: Factors Affecting Career Choices, Responsibilities of
Employers/Manager, Career Counseling-Designing Career Development System, Employee
Counseling.
Books Recommended for Unit VI
1. K.Aswathappa, Human Resources &Personnel Management, McGraw Hill Publication
Unit VII Marketing Management: Market potential analysis, Sales Analysis and Forecasting,
Methods of estimating current demand, New product development and test Marketing,
Advertising research, Media research, Market segmentation and Brand Positioning, target
marketing, Export Marketing Research, Information requirements of international marketers,
Data gathering techniques, Analysis and Interpretation of the Data and preparation of the report.
Reference: G.C. Beri, Marketing Research, Tata McGraw- Hill Publishing Company Limited