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Ans: A
Ans: B
3. Based on what you know about fibrous protein structure and sequence, what type of
fibrous protein is this sequence most likely to from (You can assume that the protein
is longer than what is shown and is repeating as shown, also note the polarity of each
amino acid.)?
Val Cys Lys Val - Cys Ala Cys - Val Cys Lys Val - Cys Ala Cys
A)
B)
C)
D)
a keratin
keratin
collagen
This sequence cannot be from any of the structural proteins.
Ans: A
Asn: B
6. Woolen clothes shrink if they are washed in hot water and dried in hot, while silk ones
dont. Can you explain why?
Asn:
wool is characterized by extensive polypeptide chains which are converted into shorter ahelices by hot, instead b-sheet of silk proteins are more stable than wool due to their
small and close side chains
7.
A)
B)
C)
D)
Ans: D
9.
A)
B)
C)
D)
E)
Ans: A
Ans: C
Ans: C
Ans: A
Ans: A
17. IgG is one of five classes of antibodies that can be produced by our immune system.
IgGs have a molecular mass of approximately 150 kDa, what is their subunit composition?
A) 2 light chains and 2 heavy chains
B) 2 light chains, 2 heavy chains, and a J chain
C) 4 light chains, 4 heavy chains, and a J chain
D) 6 light chains, 6 heavy chains, and a J chain
E) 10 light chains, 10 heavy chains , and a J chain.
Ans: A
18. Humoral immunity refers to that part of the immune response that is mediated by
A) T lymphocytes.
B) antibodies.
C) antigens.
D) the thymus.
E) the skin.
Ans: B
20. The graph below shows the O2-binding curves for myoglobin (Mb) and hemoglobin (Hb).
a. Label the two curves (indicate which one represents Mb and which one represents Hb).
b. What is the difference between myoglobin and hemoglobin that cause the O2-binding
curves to so be different?
c. Why is it important that hemoglobin has these particular O2-binding characteristics?
Asn:
a. See the graph
b. b. Mb has one subunit, Hb has 4 subunits. The sigmoid binding curve is a consequence of
positive cooperativity between the 4 O2-binding sites in Hb. The hyperbolic binding curve
for myoglobin is the result of oxygen binding reaction being noncooperative.
c. As a consequence of positive cooperation Hb has a high affinity for O2 when the O2
concentration is high (in the lungs) and low affinity for O2 when the O2 concentration is low (in
the tissues). As a consequence Hb binds large amount of O2 in the lungs and releases large
amounts of O2 in the tissues, resulting in efficient transport of O2.