Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
com
Abstract
Objective: This study was intended to investigate temperament and character traits in bipolar disorder patients with or without a history of
attempted suicide.
Methods: One hundred nineteen patients diagnosed with euthymic bipolar disorder based on Diagnostic and Statistical Manual of Mental
Disorders, Fourth Edition, Text Revision, and with no accompanying Axis I and II comorbidity, and 103 healthy controls were included.
Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I and II disorders were used to
exclude Axis I and II comorbidity. Temperament and character traits of bipolar patients with a history attempted suicide (25.2%, n = 30) or
without (74.8%, n = 89) and of the healthy volunteers were determined using the Temperament and Character Inventory. The association
between current suicide ideation and temperament and character traits was also examined.
Results: Bipolar patients with or without a history of attempted suicide had higher harm avoidance (HA) scores compared with the healthy
controls. Persistence scores of bipolar patients with no history of attempted suicide were lower than those of the healthy controls. Selfdirectedness (SD) scores of the bipolar patients with a history of attempted suicide were lower than those of patients with no such history.
Self-transcendence scores of bipolar patients with no history of attempted suicide were lower than those of both the healthy controls and of
those patients with a history of attempted suicide. A positive correlation was determined between current suicidal ideation scale scores and
HA, and a negative correlation between SD and cooperativeness was determined.
Conclusions: High harm avoidance may be a temperament trait specific to bipolar disorder patients. However, it may not be correlated with
attempted suicide in such patients. These may have low persistence, high SD and low self-transcendence temperament and character traits
that protect against attempted suicide. Harm avoidance, SD, and cooperativeness may be correlated with current suicidal ideation.
2012 Elsevier Inc. All rights reserved.
1. Introduction
Studies investigating temperament and character traits in
bipolar disorder patients have grown rapidly in recent years.
The Temperament and Character Inventory (TCI) is
frequently used in these studies. The most frequently
identified temperament traits in bipolar disorder measured
1097
1098
Table 1
Comparison of bipolar and control group sociodemographic characteristics
Sex
Female
Male
Mean age (mean SD)
Education
(years spent in)
(mean SD)
Marital status
Married
Single
Socioeconomic status
Low
Middle
High
Living in
Province
Subprovince
Village
Total
Bipolar patients
(n = 119), %
Controls
(n = 103), %
2/t
84 70.6
35 29.4
38.18 13.00
74 71.8
29 28.2
36.84 11.65
0.003
NS
0.803
NS
11.29 3.45
12.05 3.80
1.540
NS
58 48.7
61 51.3
62 60.2
41 39.8
2.474
NS
4 3.4
108 90.7
7 5.9
11 10.7
89 68.4
3 2.9
5.575
NS
84 70.6
23 19.3
12 10.1
119 100.0
69 67.0
24 23.3
10 9.7
103 100.0
0.523
NS
3. Results
3.1. Comparison of the bipolar disorder and control groups
in terms of sociodemographic characteristics
There was no difference between the bipolar disorder and
control groups in terms of sociodemographic variables (age,
sex, years spent in education, marital status, socioeconomic
level, and place of residence) (P N .05) (Table 1). At least 1
previous suicide attempt was determined in 25.2% (n = 30)
of the patients with bipolar disease. No difference in terms of
sociodemographic variables was determined between bipolar
disorder patients with or without a history of attempted
suicide (P N .05).
3.2. Comparison of the bipolar disorder and control groups
in terms of temperament and character traits
Harm avoidance scores were higher in the bipolar
disorder group compared with the control group (P =
.002), and the difference was small (effect size, 0.42).
Persistence scores were lower (P = .005), and the difference
Table 2
Comparison of bipolar disorder and control group TCI scores
NS
HA
RD
PS
SD
CO
ST
18.30 4.77
19.17 5.81
14.23 2.74
4.44 1.85
26.08 7.13
27.28 5.90
18.09 6.50
NS
.002
0.42 a
NS
.005 0.38 a
NS
NS
NS
Significance, P b .05.
a
Small effect size.
18.04 5.28
16.77 5.69
13.88 3.29
5.15 1.87
25.93 6.89
26.93 6.22
19.28 5.22
0.390
3.099
0.868
2.829
0.161
0.434
1.511
Effect sizes
1099
Table 3
Comparison of bipolar patients with or without a history of attempted suicide in terms of TCI scores
NS
HA
RD
PS
SD
CO
ST
Controls (n = 103)(1)
Suicide (n = 30)(2)
Nonsuicide (n = 89)(3)
18.04 5.28
16.77 5.69
13.88 3.29
5.15 1.87
25.93 6.89
26.93 6.22
19.28 5.22
17.07 3.70
19.73 6.28
13.73 2.75
5.07 1.44
23.17 7.24
27.33 4.96
20.60 5.91
18.72 5.28
18.98 5.67
14.40 2.73
4.22 1.93
27.07 6.85
27.27 6.21
17.25 6.50
1.301
4.980
0.935
6.403
3.576
0.095
4.818
NS
.008
NS
.002
.030
NS
.009
Effect size ( 2)
0.13 a
1/2,1/3
0.06 a
0.17 b
1/3
2/3
0.15 b
1/3, 2/3
Non-suicide t
attempt
(n = 89)
Effect
size
1100
Table 5
Correlations between TCI and suicide ideation scale score for all bipolar patients (n = 119)
Suicide ideation
scale
NS
HA
RD
PS
SD
CO
ST
r = 0.127
P = .167
r = 0.315
P = .000
r = 0.114
P = .219
r = 0.039
P = .677
r = 0.582
P = .000
r = 0.336
P = .000
r = 0.241
P = .008
Table 6
Correlations between TCI and suicide ideation scale scores for bipolar patients with attempted suicide (n = 30)
NS
HA
RD
PS
SD
CO
ST
r = 0.204
P = .279
r = 0.206
P = .275
r = 0.086
P = .650
r = 0.122
P = .521
r = 0.659
P = .000
r = 0.454
P = .012
r = 0.194
P = .303
1101
1102
[35] Zouk H, Tousignant M, Seguin M, Lesage A, Turecki G. Characterization of impulsivity in suicide completers: clinical, behavioral and
psychosocial dimensions. J Affect Disord 2006;92(2-3):195-204.
[36] Engstrm C, Brndstrm S, Sigvardsson S, Cloninger R, Nylander PO.
Bipolar disorder: III: harm avoidance a risk factor for suicide attempts.
Bipolar Disord 2004;6:130-8.
[37] Joyce PR, Light KJ, Rowe SL, Cloninger CR, Kennedy MA. Selfmutilation and suicide attempts: relationships to bipolar disorder,
borderline personality disorder, temperament and character. Aust N Z J
Psychiatry 2010;44(3):250-7.
[38] Gao K, Tolliver BK, Kemp DE, Ganocy SJ, Bilali S, Brady KL, et al.
Correlates of historical suicide attempt in rapid-cycling bipolar
disorder: a cross-sectional assessment. J Clin Psychiatry 2009;70(7):
1032-40.
[39] zerdem A, Yazc O, Tunca Z, Oral ET, Vahip S, Kurt E, Mood
Disorders Study Group, Psychiatric Association of Turkey and K Trpan.
Establishment of computerized registry program for bipolar illness in
Turkey: SKP-TRK. J Affective Disord 2004;78(Suppl 1):86.
[40] Cloninger CR, Svrakic DM, Przybeck TR. A psychological model of
temperament and character. Arch Gen Psychiatry 1993;50:975-90.
[41] Kose S, Sayar K, Kalelioglu U, Aydin N, Ak I, Kirpinar I, et al. Turkish
version of the TCI: reliability, validity, and factorial structure. Bull
Clin Psychopharmacol 2004;14:107-31.
[42] Linehan MM, Nielsen SL. Assessment of suicide ideation and
parasuicide: hopelessness and social desirability. J Consult Clin
Psychol 1981;49:773-5.
[43] Dilbaz N, Holat H, Bayam G, Tzer T, et al. ntihar Dncesi
leinin Geerlilik ve Gvenirlii. XXXI. UlusalPsikiyatriKongresi:
Istanbul; 1995 (in Turkish).
[44] First MB, Robert L, Spitzer RL, Gibbon M, Williams JBW. Structured
clinical interview for DSM-IV axis I disorders (SCID-I). Washington,
DC: American Psychiatric Press; 1997.
[45] zkrkgil A, Aydemir O, Yldz M, Danac AE, Krolu E. DSMIV Eksen I bozukluklar iin yaplandrlm klinik grmenin
Trke'ye uygulanmas ve gvenirlik almas. la vet edavi dergisi
1999;12:233-6 (in Turkish).
[46] Spitzer RL, Williams JBW, Gibbon M, First M. Manual for the
structured clinical interview for DSM-III-R personality disorders.
American Psychiatric Press: Washington, DC; 1990.
[47] Sorias S, Saygl R, Elbi H, Vahip S, Mete L, Nifirne Z, et al.
Structured clinical interview for DSM-III-R personality disorders.
Turkish version. Izmir: Ege University Press; 1990 (in Turkish).
[48] Hinkle DE, Wiersma W, Jurs SG. Applied statistics for the behavioral
sciences. New York: Houghton Mifflin Company; 1998.
[49] Cloninger CR, Przybeck TR, Svrakis DM, Wetzel RD. The
temperament and character inventory (TCI): a guide to its development
and use. St. Louis, MO: Washington University, Center of
Psychobiology of Personality; 1994.
[50] Goldman RG, Skodol AE, McGrath PJ, Oldham JM. Relationship
between the Tridimensional Personality Questionnaire and DSM-III-R
personality traits. Am J Psychiatry 1994;151(2):274-6.
[51] Mulder RT. Personality pathology and treatment outcome in major
depression: a review. Am J Psychiatry 2002;159(3):359-71 [Review].
[52] Svrakic DM, Draganic S, Hill K, Bayon C, Przybeck TR, Cloninger CR.
Temperament, character, and personality disorders: etiologic, diagnostic,
treatment issues. Acta Psychiatr Scand 2002;106(3):189-95.
[53] Cloninger CR, Svrakis DM, Bayon C, Przybeck TR. Measurements of
psychopathology as variants of personality. In: & Cloninger CR,
editor. Personality and Psychopathology. Washington, DC: American
Psychiatric Press, Inc.; 1999. p. 33-65.
[54] Fountoulakis KN, Gonda X, Siamouli M, Rihmer Z. Psychotherapeutic
intervention and suicide risk reduction in bipolar disorder: a review of
the evidence. J Affect Disord 2009;113:21-9.
[55] Cloninger CR, Zohar AH, Hirschmann S, Dahan D. The psychological
costs and benefits of being highly persistent: personality profiles
distinguish mood disorders from anxiety disorders. J Affect Disord
2012;136(3):758-66.
Reproduced with permission of the copyright owner. Further reproduction prohibited without permission.