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also eliminates excess hydrogen ions and helps maintain the pH of the
body fluids within a normal range.
3. What is the electron transport system? What is its role in hyperthermia?
4. What is the mechanism for the development of hyperkalemia in this case?
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MH is a subclinical myopathy that allows large quantities of calcium to be released from the sarcoplasmic
reticulum (SR) of skeletal muscle and cause a hypermetabolic state after exposure to triggering agents. Altered
calcium channel gating kinetics in the SR is the underlying cause. The sustained elevation of calcium allows
excessive stimulation of aerobic and anaerobic glycolytic metabolism, which accounts for respiratory and
metabolic acidosis, rigidity, altered cell permeability, and hyperkalemia.