SRI VENKATESWARA COLLEGE OF PHARMACY

RVS NAGAR, CHITTOOR (AP) INDIA

QUESTION BANK
IMPORTANT AND PREVIOUS YEARS UNIVERISTY QUESTIONS OF
PHARMACOTHERAPEUTICS I FOR 2ST YEAR PHARM.D (DOCTOR OF
PHARMACY)
(Note: Highlighted in Blue colours are the Previous Years University
Questions)
Topic 1 : CARDIOVASCULAR SYSTEM
1. Discuss the pathophysiology and drug therapy of Atherosclerosis
2. Classify drugs used in atherosclerosis with suitable examples. What is the nonpharmacological treatment of atherosclerosis
3. Write the aetiology and drug treatment of congestive heart failure
4. Describe the pathophysiology and symptoms of cardiac arrhythmia
Discuss the therapeutic approach employed in the management of major cardiac
arrhythmias
5. Discuss the aeitology and drug treatment of congestive heart failure
6. Describe the symptoms and drug treatment of Myocardial Infarction
7. Write the pathophysiology of hyperlipidaemia
Discuss the management of cardiac arrythmias
Explain various diagnostic tests of Angina Pectoris
8. Write the treatment of Hypertension
Write the diagnosis of myocardial infarction
9. Explain pathophysiology and pharmacotherapy of angina pectoris
10.Describe the electrophysiology of heart
11.Explain the pathophysiology and pharmacotherapy of congestive cardiac failure
12.Write a note on antihyperlipidemic agent
13.Explain pharmacotherapy of hypertension
14.Define the term Hypertension. Classify Blood Pressure in Adults. Write about
the Pathophysiology, Clinical Presentation, Diagnosis, and Treatment of
hypertension. List out the primary antihypertensive agents.
15.a. What are the six compelling indications identified by JNC 7 and explain the
therapeutic management using specific antihypertensive agents for those
compelling indications.
b. Explain briefly about the Hypertension in Pregnancy and its therapeutic
management.
16.a. What are Hypertensive Urgencies and Emergencies? List out various
Antihypertensive drug classes
used to treat Hypertensive Urgencies and
Emergencies.
b. Add a note on Life style modifications to prevent and manage Hypertension.
17.Define the term Heart Failure. Write about the Pathophysiology, Clinical
Presentation, Diagnosis, and Treatment of Hear Failure. Add a note on The
Prepared by: S.Wasim Raja, M.Pharm., Asst. Professor, Department of Pharmacy Practice

SRI VENKATESWARA COLLEGE OF PHARMACY

RVS NAGAR, CHITTOOR (AP) INDIA
American College of Cardiology/American Heart Association heart failure (HF)
staging system.
18.Explain briefly about the Drug therapies of Heart Failure for Routine Use
19.Explain briefly about the Drug therapies of Heart Failure for Selected Patients
20.Write about the Pharmacotherapy of Acute Decompensated Heart Failure
21.Define Angina. How will you grade Angina using NYHA functional scale. List out
the triggers , symptoms and signs of angina attack.
22.How will you restore myocardial oxygen balance in angina patients? Tabulate
the strategy, methods and example of it.
23.Explain briefly about the drug selection in Stable Angina.
24.Compare Classic angina with Myocardial Infarction
25.Write in detail about the step wise management of Myocardial Infarction &
Compare Fibrinolytic agents used in MI.
26.
Define hyperlipidaemias . Write about the Pathophysiology, Clinical
Presentation, Diagnosis, and Treatment of Hyperlipidaemias.
27.
Write about the electrophysiology of Heart. Define Arrhythmia and Write
about the Pathophysiology, Clinical Presentation, Diagnosis, and Treatment of
Arrhythmia
28.
Classify Antiarrhytmic agents and list out major side effect of it.
Topic 2:
RESPIRATORY SYSTEM
Write about the rational use of drugs in Asthma
29.Write short notes on Diagnosis test of COPD
30.Explain the etiology and Pharmacotherapy of chronic obstructive airways disease
31.Write about the diagnostic importance of pulmonary function test
32.What is meant by Pulmonary Function Test (PFT) ? Explain briefly about various
PFT. Draw the typical spirometry of normal subjects and asthma patients.
33.Define Asthma according to NAEPP. Write about the pathophysiology, Clinical
Presentation, Diagnosis and Pharmacotherapy of Asthma.
34.Summarize the stepwise management of Asthma in adult. Compare the Inhaled
bronchodilators.
35.Write about the management of acute asthma in adults in Emergency
Department.
36.List out various Drug Induced Pulmonary Diseases and highlight the
pathogenesis and treatment of any two of it.
ENDOCRINE SYSTEM
1. Write about the rational use of drugs in following disorders
a) Osteoporosis
b) Diabetes mellitus
2. Explain the following:
a) Pharmacological and Non Pharmacological management of diabetes mellitus
b) Hormone Replacement Therapy in Menopause
3. Write short notes on symptoms of hypo and hyper thyroidism
Prepared by: S.Wasim Raja, M.Pharm., Asst. Professor, Department of Pharmacy Practice

SRI VENKATESWARA COLLEGE OF PHARMACY

RVS NAGAR, CHITTOOR (AP) INDIA
4.
5.
6.
7.
8.

Describe the etiology and treatment protocol for Thyroid Disorders

Summarize about hormone replacement therapy
a. Explain etiopathogenesis and pharmacotherapy of osteoporosis
a. Explain etiopathogenesis and pharmacotherapy of Diabetes mellitus
Define the term Diabetes Mellitus. Classify Diabetes mellitus. Differentiate
Type 1 DM and Type 2 DM based on Clinical Presentation. Write about the
Pathophysiology, Diagnosis of Diabetes.
9. a. What are the glycemic goals of Therapy in Diabetes Mellitus.
b. Write about the Therapeutic Management of Diabetes Mellitus.
c. Add a note on Treatment of Diabetic Complications.
10.a. Enumerate the therapeutic management of Diabetes Mellitus using Insulin
Sensitizers.
b. What are Insulin secretagogue ? Give example and write about the therapeutic
management of Diabetes mellitus using Insulin secretagogue.
c. Give an example for oral hypoglycemic agent which act by
i) Prolonging the half-life of endogenously produced GLP-1
ii) Preventing the breakdown of sucrose and complex carbohydrate in the
small intestine, thereby prolonging the absorption of carbohydrates.
11.a. Define Thyroid Disorders. Add a note on Thyroid Hormone Physiology.
b. What is Thyrotoxicosis? Write the Pathophysiology, Clinical Presentation &
Treatment of Hyperthyroidism.
12.a. What is Thyroid Storm? Write about the treatment of Thyroid Storm.
b. What is Myxedema Coma? Write about the treatment of Myxedema Coma.
c. Add a note on Non-Pharmacologic Therapy of Hyperthyroidism.
13.What is Oral Contraceptives (OCs) ? How do OCs prevent pregnancies? List out
various types of OCs with suitable examples. Also highlight few NonContraceptive benefits of OCs.
14.Explain in detail about the role of Female hormones in Conception. Write about
various types of Oral Contraceptives with its Benefits and Risks. Add a note on
Postcoital (Emergency) Contraception.
15.a. What is Hormone Replacement Therapy? What are the drugs used in HRT?
b. Highlight the benefits & risks of HRT.
c. Explain briefly about the indications & contraindications of starting the HRT.
Topic 3 : GENERAL PRESCRIBING GUIDELINES
1. Discuss the measures to be adopted in providing drug therapy to Geriatrics
2. Discuss in detail the general principles of pharmacotherapy in pregnancy and
lactation
3. Discuss the measures to be adopted in providing drug therapy to pediatric
patients
4. Discuss in detail the general principles of pharmacotherapy in a) Geriatrics
b)Pregnancy
5. Write the prescribing guidelines for paediatrics
Prepared by: S.Wasim Raja, M.Pharm., Asst. Professor, Department of Pharmacy Practice

SRI VENKATESWARA COLLEGE OF PHARMACY

RVS NAGAR, CHITTOOR (AP) INDIA
6. Write short notes on prescribing guidelines for breast feeding.
7. Enumerate the general prescribing guidelines for geriatric patients.
8. Write about the general prescribing guidelines for Pregnancy and Breast feeding
Topic 4: OPTHALMOLOGY
1. Describe the etiology and drug treatment for the following : Glaucoma ,
Conjunctivitis
2. Discuss the etiopathogenesis and pharmacotherapy of Glaucoma
3. Discuss the therapeutic management of glaucoma & Write the treatment of
viral conjunctivitis.
4. Describe the pharmacotherapy of Glaucoma
5. Discuss the pharmacotherapy of viral and bacterial conjunctivitis
6. a. What is Glaucoma? Explain briefly about the Pathophysiology, clinical
presentation, diagnosis of Glaucoma.
b. What are the Topical drugs used in the Treatment of Open-Angle Glaucoma.
c. What are risk factors for developing Glaucoma?
7. What is Glaucoma ? List out various types of Glaucoma and highlight the
optic disk and visual field changes associated with Glaucoma. Add a note on
therapeutic management of Primary Open Angle Glaucoma with the help of
brief flow chart and list out Pharmacological Agents used in it.
8. What is Conjunctivitis? Classify it. Write the signs and symptoms of Viral and
Bacterial Conjunctivitis. Tabulate the relevant clinical findings in external and
biomicroscopical evaluation of Patients with conjunctivitis. Add a note on
therapeutic management of Viral and Bacterial Conjuctivitis.

Topic 5: INTRODUCTION TO RATIONAL DRUG USE

1. a. Write a note on essential drug concept b. Discuss the role of pharmacist in
promoting rational drug use.
2. Write a note on rational use of antibiotics
3. Add a note on rational use of injections
4. Write short notes on the following
a. National Drug Policy
b. Medications use in India
c. Guidelines for
rational prescribing
5. Add a note on rational use of antibiotics
6. Write a note on rational use of OTC drugs
7. a. Write a note on essential drug concept
b. What are rational drug formulations? Explain with the help of examples
8. Write a note on rational drug use.
9. What are essential drugs? Discuss the role of pharmacist in essential drug
concept.

Prepared by: S.Wasim Raja, M.Pharm., Asst. Professor, Department of Pharmacy Practice

SRI VENKATESWARA COLLEGE OF PHARMACY

RVS NAGAR, CHITTOOR (AP) INDIA
10.Explain briefly about the definition, Role of Pharmacist in Essential drug
concept and Rational drug formulations.

Prepared by: S.Wasim Raja, M.Pharm., Asst. Professor, Department of Pharmacy Practice