UNIVERSITI TUNKU ABDUL RAHMAN

CENTRE FOR FOUNDATION STUDIES

FOUNDATION IN SCIENCE
MAY 2015
FHSB1214
BIOLOGY I
TUTORIAL 12
MENDELIAN GENETICS II
Students Guide:
At university level, the tutor facilitates student learning without spoon-feeding. Therefore,
you are expected to:
Read your textbook, attempt the questions before the tutorial
You may enter the class and sign your attendance after showing your tutor that all

tutorial questions have been completed; even if you dont know how to do, write
something - youre not advised to leave answers blank in the finals.
Write answers on board if you wish to receive tutor feedback
(no answer, no feedback)
Be independent: consult textbooks or dictionaries on your own first before asking the
tutor
All questions are compulsory. 1 mark may reflect 1 answer point.
(No half mark is awarded in the finals marks)
(Source: Final Examination, December2014)
Q1.
Figure 1 shows the inheritance of straight hairline in Tom Scavos family. In the
entire Scavo family, only Tom, his mother and his brother has straight hairline
(Figure 2A). The rest if the family members have widows peak (Figure 2B).

Figure 1

Figure 2A

Q2.

Figure 2B

Figure 2C

(i)

State whether straight hairline is determined by a dominant allele or recessive

allele.
(1
mark)

(ii)

Let the dominant allele be represented by H, and the recessive allele

represented by h. State the possible genotypes(s) of Tom, his father, his mother
and the two sisters.
(4
marks)

(iii)

Tom is married to Lily (Figure 2C). State the probability of their first child to
have widows peak. Use a Punnett square to support your answer.
(3
marks)

(a)

The shapes and colours in carrots are determined by different alleles. Both of
the alleles did not show dominancy. Each genotype produces different
phenotypes. Colours of carrot are red (CRCR), purple (CRCW) or white (CWCW).
The shapes are long (SLSL), oval (SLSN) or round (SNSN).
(i)

State the type of inheritance shown by the shape and colour of carrot.
(1
mark)

(ii)

The long, red carrot is crossed with the round, white carrot. Using a
genetic diagram, show the F1 generation.
(5
marks)

(iii)

If F1 is self-crossed, what is the chance of obtaining offspring with red,

oval carrots? Show the genetic diagram and Punnett square.
(7
marks)

(Source: Final Examination, Apr 2012)

Q3.
(a)
Figure 2 is a pedigree showing the inheritance of sickle-cell
disease. Sickle-cell disease is an autosomal disorder
characterized by the presence of sickle-shaped red blood cells.
Let the dominant allele be represented by N and recessive
allele be represented by n.

Figure 2
(i)

State the possible genotype(s) of individuals 4, 8 and 14.

(3

marks)
(ii)
Individual 6 was married to individual 11. Using a
Punnett square, explain all the possible genetic combinations
in their children.
(3
marks)
(iii)

State the probability that the next TWO children of

couple 3 and 4 will be affected. Show your calculation.
(1 mark)

(Source: Final Examination, Apr 2011, truncated)

Q4.
Figure 3 shows a pedigree for the inheritance of a particular autosomal trait in
humans. This trait is characterized by the inability to taste the bitterness of
phenylthiocarbamide (PTC).

Figure 3
(a)

What is the mode of inheritance for the trait shown by the pedigree?
mark)

(b)

What are the evidences from the pedigree that justifies your answer for part
(a)?
(4
marks)

(c)

Given these symbols: Q for dominant allele and q for ressesive allele,
determine/give answers for the following. Show the Punnett square (where
possible) in your answers.
(i)
Give the genotype for individuals no.1, no.7 and no.17.
marks)

(1

(3

(ii)
marks)

What is the probability for parents no. 8 and 9 to have their next child
to be normal?
(3