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Usual Diluents
NS, D5W,LR.
Reconstitution
Note: Multiple concentrations: Docetaxel is available as a one-vial formulation at
concentrations of 10 mg/mL (generic formulation) and 20 mg/mL (concentrate;
Taxotere, and as a lyophilized powder (Docefrez) which is reconstituted (with
provided diluent) to 20 mg/0.8 mL (20 mg vial) or 24 mg/mL (80 mg vial).
Admixture errors have occurred due to the availability of various concentrations.
Docetaxel was previously available as a two-vial formulation which included two
vials (a concentrated docetaxel vial and a diluent vial), resulting in a reconstituted
concentration of 10 mg/mL; the two-vial formulation has been discontinued by the
manufacturer.