Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Linda Sykora
lmsykora@unmc.edu
WBC count
RBC count
Hemoglobin
Hematocrit
RBC Indices (MCV, MCH, MCHC, RDW)
Platelet count
Differential
WBC differential and cell morphology
Reticulocyte count
Erythrocyte Sedimentation Rate (ESR)
1
WBC Count
Adult CBC
11-17 g/dL
x3=45.0
RBC
Parameters
=RBC
size
82-98 fL
RBC
Indices
Significance
WBC count
count.Leukopenia
Decreased production, increased use
WBC count
count.Leukocytosis
Increased production, shift/pseudo
>150 K/uL
7
Significance
10
RBC Indices
Evaluation:
3 adults
Small
lymph
11
Microcytic RBCs
Macrocytic RBCs
RBC Indices
RBC Indices
Normocytic RBCs
MCV 8282-98 fL
Microcytosis
MCV <82 fL
Macrocytosis
MCV >98 fL
13
14
RBC Indices
Evaluation:
3 adults
Homogeneous Population
Heterogeneous Population
16
Evaluation:
Evaluation:
Schistocytes
Spherocyte
Spherocyte
18
Platelet Count
Platelet Count
Hardest cell type to count
Reference range
150,000150,000-450,000/uL
Significance
PLT count
count.Thrombocytopenia
Sample must be
redrawn to obtain
accurate results
PLT count
count.Thrombocytosis
Increased production, postpost-splenectomy
Blood smear
Platelet
Platelet Clumps
19
20
CBC
DIFF
WBC
Types
A puppy
puppy paw
% x WBC/uL
21
22
Differentials
Differential includes:
WBC differential that classifies WBC types
Reported in % and absolute # (% x WBC count)
% easier to evaluate but absolute # more reliable
Blood
Smear
Significant variations
from normal are noted
24
Differentials
Reticulocyte Count
Significance:
NRBC
Polychromasia
26
Reticulocyte Count
Wright
Wrights stained smear
Reticulocytes
2525-100,000/cmm Absolute#
Significance
absolute Retic count
count.Reticulocytopenia
Abn
Significance
Rouleaux
Clinical use
28
30
Example of hemodilution:
hemodilution:
Evaluation:
Next step:
1. Order a differential to identify WBC types and cause
for WBC count
2. Request a redraw to confirm the platelet count
3. Order a retic count to access RBC production
31
Evaluation:
Next step:
1. Order a differential to identify WBC types
2. Request a redraw to confirm the platelet count if no
signs of bleeding
3. Order a retic count to access RBC production
33
Bacterial
infection
35
36