Specific Learning Objectives

N
o.

Departmen
t

Specific Learning Objectives

1.

Anatomy

Explain the anatomy of spleen & liver and their related organs
Identify and describe the gross anatomy of the organs and tissues of the
lymphatic system

Identify the major lymphatic vessels, lymph nodes, and organs of the lymphatic
system

Explain lympahtic system and drainage

2.

Histology

Explain the histology of the organs and tissues of the lymphatic

system including lymph node, spleen and tonsils
Explain the structure and function from organs and tissues of
the lymphatic system including lymph node, spleen and tonsils

3.

Physiology

Explain the structure and function of RBC

List organs producing the RBCs
Explain the erythropoiesis (including normal and abnormal maturation)
Explain the role of erythropoietin and tissue oxygenation in the regulation
of RBC production
Explain the role of several factors involved in the maturation of RBC
Explain the development, structure and function of haemoglobin.
Explain the mechanism of RBC destruction
Explain the erythropoiesis dependent on age (including normal and
abnormal maturation)
Describe the condition cause tissues hypoxia

Explain physiology of the lymph node

4.

Biochemist

Explain

the role of iron, vit B12 and folic acid for RBCs

ry

production
Explain the metabolism of vit B12 and folic acid
Explain absorbtion, fate and excretion of Fe
Explain the structure & function of hemoglobin
Explain the cooperativity of Hemoglobine
Explain the effect of NADH, NADPH & 2.3 BPG to hemoglobin
Explain the effect of ATP to RBC membrane
Explain recent advances cellular respon in infectious disease

5.

Clinical
Pathology

Analyze the laboratory assessment of RBC (number, Hb content, Hct,

Erythrocyte Index, Red Cell Distribution Width Reticulocyte, Peripheral
blood smear

Explain the development and morphology of Erythropoietic

system
Explain the development and morphology of Granulopoietic
system
Explain the development and morphology of Megakaryopoietic
system
Explain the development and morphology of the Lymphopoietic
system
Explain maturation changes in all blood cells, such as: size,
chromatin, shape, and cytoplasm.

Explain the physiology of hemostasis

Apply Diagnostic approach to bleeding

thrombotic diseases)

disorder (hemorrhagic and

Classify vascular disorders

Explain the etiology, patophysiology, sign and symptoms,

management, prognosis of vascular disorders.
Explain the definition of platelet disorders.
Explain the platelet function in hemostasis and thrombosis.
distinguish the types of platelet disorders.

Explain the etiology of platelet disorders.

Explain the pathogenesis of platelet disorders.
Explain the signs and symptoms of platelet disorders.
Apply the laboratory findings of platelet disorders.
Explain the differential diagnosis of platelet disorders.
Explain the management of platelet disorders.
Explain the course and prognosis of platelet disorders (C4).

Explain basic concept of blood transfusion, reaction of blood

transfusion and stem cell transplantation

Explain the principle of Immunodiagnostic.

Explain the definition, mechanism and classification of immunodeficiency.

Explain immunotolerance, immunostimulance, and immunosupression.

Apply laboratory assays to establish the diagnosis of Rheumatoid Arthritis

6.

Internal
Medicine

Explain the definition of anemia.

Assess the symptoms of anemia in adult and children.
Identify physical signs of anemia in adult and children.
Evaluate the laboratory findings of anemia.
Classify RBC disorders into 3 categories.
Explain the definition of iron deficiency anemia.
Explain the etiology of iron deficiency anemia in adult and children.
Explain the pathogenesis of iron deficiency anemia including the stages in
the development of iron deficiency.
Explain signs and symptoms of iron deficiency anemia in adult and
children.
Evaluate the laboratory findings of iron deficiency anemia (C6).
List the differential diagnosis of iron deficiency anemia (C6).
Explain evaluate the management of iron deficiency anemia (C6).
Explain the course and prognosis of iron deficiency anemia
Explain the definition of hemolysis and hemolytic anemia.
Classify the types of hemolytic anemia into 2 categories.
Explain the etiology, pathogenesis and pathophysiology of hemolytic
anemia.
Explain the signs and symptoms of hemolytic anemia.
Evaluate the laboratory findings of hemolytic anemia.
Explain the differential diagnosis of hemolytic anemia.

Explain the complications of hemolytic anemia including 2 types of crisis

in hemolytic anemia.
Explain the management of hemolytic anemia including the indication of
splenectomy.
Explain the course and prognosis of hemolytic anemia.
Explain the definition of aplastic anemia.
Explain the etiology of aplastic anemia ..
Explain the pathogenesis and pathophysiology of aplastic anemia ..
Explain the signs and symptoms of aplastic anemia.
Explain the laboratory findings of aplastic anemia.
Explain the severity of aplastic anemia.
Explain the differential diagnostic of peripheral pancytopenia.
Explain the management of aplastic anemia.
Explain outline the course and prognosis of aplastic anemia
Explain the definition of megaloblastic anemia.
Explain the etiology of megaloblastic anemia.
Explain the pathogenesis and pathophysiology of megaloblastic anemia.
Explain the etiology of folic acid and cobalamin (vitamin B12) deficiency.
Explain the pathogenesis of folic acid and cobalamin deficiency.
Explain the signs and symptoms of folic acid and cobalamin deficiency.
examine the laboratory findings of folic acid and cobalamin deficiency.
Explain the differential diagnosis of folic acid and cobalamin deficiency.
Explain the treatment of folic acid and cobalamin deficiency.
Explain the course and prognosis of folic acid and cobalamin deficiency.
Explain the structure and maturation of leucocytes (normal and
abnormal).
Explain the function of leucocytes.
Explain the definition of MDS and acute leukemia.
Explain the types of acute leukemia into 2 categories.
Explain the etiology of MDS, acute myelogenous leukemia (AML) and
acute lymphoblastic leukemia (ALL).
Explain the pathogenesis of, MDS, AML, and ALL.
explain the classification of MDS, AML, and ALL.
Explain the signs and symptoms of MDS, AML , and ALL.
examine the laboratory findings of MDS, AML, and ALL.
Explain the differential diagnosis of MDS, AML, and ALL.
Explain the management of MDS, AML, and ALL.
Explain the course and prognosis of MDS, AML, and ALL

Explain the etiology of lymph nodes enlargement

Explain the definition of lymphadenopathy
Explain the classification of lymphadenopathy
Explain the physical finding of lymphadenopathy to evaluate the possible
cause of lymphadenopathy
Explain the diagnostic approach for lymphadenopathy

Explain
Explain
Explain
Explain

the
the
the
the

definition of polycythemia vera and myelofibrosis

etiology of polycythemia vera and myelofibrosis
pathogenesis of polycythemia vera and myelofibrosis
signs and symptoms of polycythemia vera and myelofibrosis

Explain the laboratory findings of polycythemia vera and myelofibrosis

Explain the differential diagnosis of polycythemia vera and myelofibrosis
Explain the management of polycythemia vera and myelofibrosis
Explain the course and prognosis of polycythemia vera
and
myelofibrosis
Describe the structure of plasmocyte .
Explain the definition of multiple myeloma .
Explain the etiology of multiple myeloma .
Explain the pathogenesis of multiple myeloma .
Explain the signs and symptoms of multiple myeloma .
Explain the laboratory findings of multiple myeloma.
Explain the differential diagnosis of multiple myeloma .
Explain the management of multiple myeloma .
Explain the course and prognosis of multiple myeloma .
Explain the definition of malignant lymphoma ..
Classify the types of malignant lymphoma into 2 categories .
Describe the classification of Non-Hodgkin Malignant Lymphoma (NHML)
(Rappaport, Lukes-Collin, Working Formulation, REAL/WHO) .
Describe the classification of Hodgkins disease (Rye classification) .
Explain the etiology of malignant lymphoma including its relation with HIV
Explain the pathogenesis of malignant lymphoma.
Explain the signs and symptoms of malignant lymphoma.
Explain the differential diagnosis of malignant lymphoma.
Explain the management of malignant lymphoma.
Explain the course and prognosis of malignant lymphoma.

Explain the etiology, clinical manifestations, patophysiology,

differential diagnosis, management, lab support, prevention
and prognosis of Lupus erytematosus
Explain the etiology, clinical manifestations, patophysiology,
differential diagnosis, management, lab support, and
prognosis of Rheumatoid arthritis
7.

Pediatrics

Explain the mechanism of coagulation in hemostatic mechanism.

Explain the definition of hemophilia.
Classify the types of hemophilia.
Explain the etiology of hemophilia A, B and C.
Explain the etiology of Hemophilia A, B and C.
Explain the signs and symptoms of Hemophilia.
explain the laboratory findings of Hemophilia A, B and C.
Explain the differential diagnosis of Hemophilia A, B and C.
Explain the management of Hemophilia A, B and C.
Explain the course and prognosis of Hemophilia A, B and C.

Explain the etiology, patophysiology, sign and symptoms,

management, prognosis of Coagulation disorders (Haemorrhagic
Diseases of the Newborn/ HDN)

Explain the etiology, patophysiology, sign and symptoms,

management, prognosis of Fibrinolysis disorders

Explain the etiology, patophysiology, sign and symptoms,

management, prognosis of Thrombotic disorders
Explain the definition of atopy and atopic dermatitis.
Explain the etiopathogenesis of atopic dermatitis, especially itch and
environment.
Explain clinical manifestation and classification of atopic dermatitis.
Explain the laboratory assays to establish the diagnosis of atopic
dermatitis (C4).
Explain the differential diagnosis of atopic dermatitis.
Explain management of atopic dermatitis.
Explain the definition of allergic rhinitis.
Explain the allergenic etiology of allergic rhinitis.
Explain the definition, etiology, pathophysiology, differential diagnosis,
treatment and prognosis of non allergic rhinitis.
Explain about non allergenic etiology of allergic rhinitis.
Explain the classical pathophysiology of hypersensitivity type I of allergic
rhinitis.
Explain the clinical manifestation of allergic rhinitis.
Explain the laboratory assays to establish the diagnosis of allergic rhinitis.
Distinguish the differential diagnosis of allergic rhinitis.
Explain the comorbidities and complications of allergic rhinitis.
Explain the management of allergic rhinitis.
Explain the definition of anaphylactic shock .
Explain the etiology of anaphylactic shock.
Explain the pathophysiology of anaphylactic shock.

Explain clinical manifestation of anaphylactic shock.

Choose laboratory assays to establish the diagnosis of anaphylactic shock.
Differentiate differential diagnosis of anaphylactic shock.
Evaluate management of anaphylactic shock.
Explain prevention of anaphylactic shock.
explain the prognosis of anaphylactic shock.
Explain
Explain
Explain
Explain
Explain
Explain
Explain
Explain

8.

definition / criteria of lupus erythematosus.

etiology of lupus erythematosus.
the pathophysiology of lupus erythematosus.
the clinical manifestation of lupus erythematosus.
the differential diagnosis lupus erythematosus.
the laboratory findings of lupus erythematosus.
the management of lupus erythematosus.
the prognosis of lupus erythematosus.

Microbiolog Apply basic concept of immunology

y
The Recognition of Antigen and Antibody :

The structure and function of antibodies

Major Histocompatibility Complex
Antigen processing and presentation

Immunity and Immune Response :

Explain :

Active immune response

Passive immune response
Innate immunity
Adaptive immunity

Explain the mechanism of inflammation reaction and structure of immuno

competent cells which happened.

9.

Nutrition

10 Pharmacol
.
ogy

11 Pathology
.
Anatomy

Explain classification
hemopoeitic agents

and

Explain classification
immunosupressant

&

Explain classification
corticosteroid drugs
Explain classification
antihistamine

pharmacological

properties

of

Pharmacological

Properties

of

&

Pharmacological

Properties

of

&

Pharmacological

Properties

of

Explain the pathogenesis type I to IV hypersensitivity and its

diseases
Explain the pathogenesis and microscopic feature of urticaria
Describe the
pathogenesis

diseases

of

autoimmune and its

general

Explain the pathogenesis of several autoimmune diseases and

its microscopic feature: systemic lupus erythematosus,
polymialgia rheumatic, anafilactic reaction, rheumatic fever,
rheumathoid artritis
Explain
the pathogenesis of acquired immunodeficiency
syndrome
Explain the disorders of white blood cells ( acute and chronic
leukemia), lymph node (lymphoma hodgkin and non Hodgkin
lymphadenopathy, lymphadenitis),
spleen and thymus
(timoma)
Explain the pathogenesis and microscopic appearance of
reactive hyperplasia of the lymph node and sinus histiocytosis
Explain the pathogenesis and microscopic appearance of
hodgkins and non hodgkins lymphoma
Explain the basic concept of tumor imunity
12 Dermatolo
.
gy

Explain structure and function of the skin and appendages.

Explain definition of atopy and atopic dermatitis .
Explain etiopathogenesis of atopic dermatitis, especially itch and
environment factors.
Explain clinical manifestation and classification of atopic dermatitis.
Apply laboratory assays to establish the diagnosis of atopic dermatitis .
Explain differential diagnosis of atopic dermatitis .
Explain the management of atopic dermatitis .

Explain the etiology, sign & symptoms, patophysiology,

differential diagnosis, management, lab support and prognosis
of urticaria and angioedema
Explain the etiology, clinical manifestations, patophysiology,
differential diagnosis, management, lab support, prevention
and prognosis of anaphylactic shock
Explain the etiology, clinical manifestations, patophysiology,
differential diagnosis, management, lab support, prevention
and prognosis of drug eruption

Explain the etiology, clinical manifestations, patophysiology,

differential diagnosis, management, lab support, prevention
and prognosis of allergic contact dermatitis
Explain the etiology, clinical manifestations, patophysiology,
differential diagnosis, management, lab support, prevention
and prognosis of chronic bullous disease
13 Opthalmic
.

Explain pathomechanisme hypersentitives with the eye cases