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Context The 1998-1999 war in Kosovo had a direct impact on large numbers of civilians. The mental health consequences of the conflict are not known.
Ferid Agani, MD
Carol A. Gotway, PhD
Design, Setting, and Participants Cross-sectional cluster sample survey conducted from August to October 1999 among 1358 Kosovar Albanians aged 15 years
or older in 558 randomly selected households across Kosovo.
N LATE FEBRUARY
1998, CLASHES IN
Kosovo between Serbian police
forces and members of the Kosovo
Liberation Army intensified.1 Serbian forces burned homes and killed
dozens of ethnic Albanians in these raids.
As a result of the fighting, thousands of
ethnic Albanians were displaced from
their homes in Kosovo; many took refuge with host families, while a smaller
proportion (several thousands) fled to the
hills and forests.1 By the time North Atlantic Treaty Organization (NATO) operations began against Serbia on March
24, 1999, about 260000 people had been
displaced within Kosovo and 199000
had fled to other countries.2 It is estimated that as result of this conflict, more
than 800000 people became refugees in
neighboring countries (mainly Albania, Montenegro, and the former Yugoslav Republic of Macedonia), as well as
secondary countries of asylum in Europe, the United States, and elsewhere.
On June 9, 1999, an agreement between NATO and Serbia was reached,
and the following day NATO halted its
bombing campaign.
As the Serbian troops began to pull
out of Kosovo, the nearly 750000 Albanians from Kosovo who had been livSee also pp 578 and 615.
JAMA. 2000;284:569-577
569
logical impact of such emergency situations is a neglected issue.3 However, recent epidemiological studies in Bosnia4
and studies among Cambodian refugees living on the Thai border5 and in
the United States have shown that psychiatric morbidity is much higher in
populations that have experienced war,
persecution, and mass violence.6,7
To estimate the prevalence of psychiatric morbidity and to identify specific vulnerable populations, the Centers for Disease Control and Prevention
(CDC) and the Institute of Mental
Health and Recovery in Kosovo, in collaboration with Doctors of the World,
conducted a mental health survey
among ethnic Albanians in Kosovo from
August 20 to October 7, 1999. The survey focused on the period of August
1998 through August 1999, when most
of the intense violence took place.
METHODS
Survey Design
house just surveyed. This process was repeated until 20 households were surveyed, or until the team leader decided
it was time to leave for security reasons.
We interviewed all adult members of
the household present. To ensure as
much privacy as possible, we encouraged people to complete the questionnaires in separate rooms, and men and
women interviewers paired up with
same-sex interviewees to help them
complete the questionnaires. A security curfew at dusk imposed by KFOR
prevented interview teams from coming back to survey adults not present
during the day. Because of the ongoing threat of land mines, KFOR considered access to some remote houses
unsafe. These homes had to be excluded from our sample and replaced
by the closest accessible household.
Native Kosovar Albanian survey team
members had 3 days of training on general survey objectives, safety precautions, procedures for proper household selection (including randomly
selecting the first household and handling special situations), and interviewing techniques (understanding the questionnaires and addressing sensitive
topics). All members of the survey team
were closely supervised for the first 2
days, and they continued to receive daily
supervision and instruction until the survey was completed. Interviewers were
instructed to refer participants who appeared to be in obvious distress to community mental health services where
available. A list of these services was procured from the nongovernmental organization coordinating office at the United
Nations Mission in Kosovo.
The study protocol was reviewed by
a CDC institutional review board representative and informed consent was
obtained verbally from all participants
(with communication occurring in the
potential participants native language).
The study protocol was also reviewed
by Doctors of the World for ethical considerations.
Screening Tools
higher scores on this scale representing better functioning. All 3 tools have
been extensively validated in many
countries and cultures and in many disease settings.16-18
To assess the effect of broadly defined demographic characteristics on
mental health status, we collected demographic information including age,
sex, education level, and marital status. We added additional questions specific to the Kosovar Albanian population on feelings of hatred and a desire
for revenge. All questionnaires were
translated into Albanian and backtranslated to English to ensure cultural appropriateness of the instrument and accuracy of the translation.
A team of Albanian translators including a psychiatrist, a psychologist, and
a primary care physician from the Institute for Mental Health and Recovery did the translation and adaptation
of the screening tools.
Data Analysis
No. of
Proportion,
Respondents*
%
Location
Rural
Urban
758
600
55.8
44.2
Sex
Female
Male
825
499
62.3
37.7
Age, y
15-34
35-54
609
459
45.3
34.1
55-64
147
10.9
$65
130
9.7
Marital status
Married
Divorced
906
31
67.3
2.3
Single
319
23.7
Widowed
Education
Less than
primary
Primary
91
6.8
313
23.3
485
36.2
Secondary
377
28.1
166
12.4
202
1134
15.1
84.9
23
1302
1.7
98.3
551
807
40.6
59.4
Some university
Currently employed
Yes
No
Previous psychiatric
illness
Yes
No
Chronic health
problems
Yes
No
RESULTS
Characteristics of
Survey Participants
571
No. (%)
904 (66.6)
903 (66.5)
870 (64.1)
837 (61.6)
778 (57.3)
664 (48.9)
646 (47.6)
568 (41.8)
470 (34.6)
359 (26.4)
324 (23.9)
298 (21.9)
240 (17.7)
202 (14.9)
131 (9.6)
60 (4.4)
293 (21.6)
529 (39.0)
374 (27.5)
162 (11.9)
231 (18.2)
326 (25.6)
715 (56.2)
Mean
(95% Confidence
Interval)
572
Table 4. Univariate Analysis of Effects of Demographic and Exposure Variables on GHQ-28 and MOS-20 Social Functioning Mean Scores
and Prevalence of PTSD*
GHQ-28 (Scale, 0-28)
Variable
Location
Urban
Mean (SE)
10.50 (0.61)
Rural
11.42 (0.92)
Sex
Male
10.80 (0.74)
Female
Current employment
Yes
No
P
Value
.41
9.14 (0.71)
Mean (SE)
40.60 (2.70)
24.08 (2.31)
.35
11.34 (0.65)
11.46 (0.66)
29.10 (3.51)
P
Value
,.001
.80
30.24 (2.46)
,.001
36.70 (3.72)
PTSD Symptoms
13.16 (2.17)
12.01 (1.85)
.006
28.20 (1.84)
12.49 (3.44)
8.33 (0.72)
33.83 (2.32)
13.22 (1.74)
26.63 (2.35)
21.44 (3.44)
55-64
14.24 (0.69)
$65
14.68 (0.76)
Marital status
Married
.03 (linear)
24.99 (2.99)
17.81 (2.89)
25.67 (3.87)
16.30 (4.69)
12.03 (0.63)
28.90 (2.29)
16.49 (2.28)
Divorced
6.37 (1.63)
32.79 (4.95)
10.48 (6.94)
Widowed
14.78 (1.24)
Single
7.69 (0.68)
.43
18.21 (3.60)
30.96 (5.32)
34.39 (2.31)
15.14 (2.21)
14.06 (0.61)
24.37 (2.73)
21.29 (3.73)
Primary
10.51 (0.77)
28.82 (2.54)
15.99 (2.42)
Secondary
10.10 (0.66)
Some university
Previous psychiatric illness
Yes
No
Chronic health condition
Yes
No
Displacement
Refugee (R)
,.001 (linear)
8.88 (0.60)
20.72 (1.80)
10.95 (0.65)
14.49 (0.37)
8.62 (0.78)
,.001
,.001
.03 (linear)
32.47 (3.74)
15.84 (1.69)
37.19 (4.33)
11.01 (4.25)
20.08 (6.48)
.20
29.56 (2.02)
24.44 (2.10)
33.30 (2.25)
.20
18.00 (2.29)
12.64 (0.66)
Education
Less than primary
.01
19.67 (2.67)
35-54
,.001
.11
19.02 (2.76)
Age, y
15-34
,.001 (linear)
P
Value
% (SE)
35.92 (12.63)
.01
.48
.11 (linear)
.15
16.81 (2.05)
,.001
21.51 (2.67)
.003
13.95 (1.90)
10.68 (0.81)
R vs I: .03
28.45 (1.66)
R vs I: .75
16.64 (2.70)
R vs I: .12
13.05 (0.78)
R vs D: .66
26.72 (5.20)
R vs D: .009
21.97 (2.55)
R vs D: .19
10.26 (0.66)
I vs D: .007
36.60 (3.03)
I vs D: .12
11.88 (2.37)
I vs D: .004
Rape
Yes
No
Forced separation
Yes
No
Murder of family or friend
Yes
No
Trauma events, No.
0-3
11.03 (1.30)
.93
11.12 (0.62)
12.22 (0.81)
.002
10.30 (0.62)
13.66 (0.49)
10.16 (0.70)
26.71 (5.21)
.55
29.67 (2.06)
27.36 (2.20)
.20
31.17 (2.69)
,.001
21.92 (3.66)
21.62 (6.91)
22.69 (3.50)
.005
32.42 (1.73)
25.48 (3.41)
42.14 (3.34)
13.40 (2.57)
9.37 (0.77)
32.49 (2.62)
10.03 (2.15)
8-11
12.43 (0.83)
12-16
16.11 (0.63)
15.66 (4.60)
.002
13.97 (1.82)
9.28 (0.57)
23.17 (2.31)
.01
13.09 (1.76)
4-7
,.001 (linear)
.49
16.92 (2.02)
,.001 (linear)
22.16 (3.66)
,.001 (linear)
32.55 (5.69)
*GHQ-28 indicates General Health Questionnaire-2810,11; MOS-20, Medical Outcomes Study13; and PTSD, posttraumatic stress disorder. See the Methods section for a description of each screening tool. P values are derived from Wald F tests (df = 28) for the difference between each group, or a linear trend.
Only 23 people in yes category.
573
cial functioning. The association between rape and psychiatric morbidity and
social functioning may be difficult to observe here because of the relatively small
number of reported rape cases.
specific psychiatric morbidity. Similarly, living in a rural setting, being currently unemployed, being older, having
little education, and reporting having
received a diagnosis of a chronic health
condition were associated with a low
(eg, worse) social functioning score.
Finally, HTQ results indicate that being
female and having received a diagnosis of a chronic health condition were
associated with PTSD symptoms.
Most traumatic event variables (forced
separation from family, murder of family or friend, and increasing number of
traumatic events) but not rape were associated with a worse score in the 3 measured mental health outcomes, with the
exception of forced separation for so-
Table 5. Demographic Variables Affecting Mental Health Outcomes, Adjusted for All Variables*
GHQ-28
(Scale, 0-28)
Variable
Location
Urban
Rural
Sex
Male
Female
Current employment
Yes
No
Age, y
15-34
35-54
Adjusted Mean
(SE)
12.19 (0.56)
10.54 (0.55)
.06
10.96 (0.45)
11.20 (0.45)
.47
10.11 (0.79)
11.28 (0.40)
.15
9.64 (0.56)
12.22 (0.42)
.006 (linear)
Adjusted Mean
(SE)
37.03 (2.37)
25.85 (1.72)
28.95 (3.31)
30.10 (2.28)
35.64 (4.07)
28.57 (1.23)
PTSD Symptoms
P
Value
.001
.82
.046
OR
(95% CI)
1.00
1.10 (0.63-1.92)
1.00
1.93 (1.09-3.41)
0.97 (0.43-2.17)
1.00
31.85 (2.32)
0.78 (0.40-1.54)
26.85 (1.62)
1.76 (0.91-3.38)
12.03 (0.72)
$65
Marital status
Married
Divorced
12.37 (0.61)
32.14 (3.74)
11.29 (0.46)
8.11 (0.83)
29.97 (1.69)
0.68 (0.37-1.24)
27.34 (6.42)
0.50 (0.08-3.22)
Widowed
12.60 (1.33)
Single
Education
Less than primary
Primary
Secondary
Some university
Previous psychiatric illness
Yes
No
Chronic health condition
Yes
No
.08
27.56 (2.61)
.91 (linear)
55-64
21.23 (3.47)
1.00
.14
1.62 (0.85-3.07)
31.62 (2.11)
11.22 (0.40)
10.65 (0.57)
31.20 (2.41)
0.78 (0.39-1.53)
31.19 (2.26)
0.63 (0.39-1.01)
.70 (linear)
10.51 (0.57)
26.75 (2.61)
,.001
13.33 (0.28)
9.40 (0.61)
,.001
27.17 (6.94)
29.72 (1.45)
26.51 (1.91)
32.11 (1.60)
.02
.94
.39 (linear)
.07
1.00
.50 (linear)
28.28 (4.51)
18.00 (1.00)
10.98 (0.38)
.74
0.67 (0.30-1.48)
10.41 (0.48)
11.84 (0.53)
P
Value
1.00
.92 (linear)
0.70 (0.27-1.87)
.73
.01
2.87 (1.22-6.76)
1.00
1.44 (0.89-2.33)
1.00
.02
.13
*GHQ-28 indicates General Health Questionnaire-2810,11; MOS-20, Medical Outcomes Study13; PTSD, posttraumatic stress disorder; OR, odds ratio; and CI, confidence interval.
See the Methods section for a description of each screening tool.
Indicates change to not significant from univariate analysis.
Indicates change to significant from univariate analysis.
574
Table 6. Exposure Variables Affecting Mental Health Outcomes, Adjusted for All Demographic Variables*
GHQ-28 (Scale, 0-28)
Variable
Displacement
Refugee (R)
Internally displaced (I)
Did not move (D)
Rape (HTQ)
Yes
No
Forced separation (HTQ)
Yes
No
Murder of family or friend (HTQ)
Yes
No
Trauma events, No.
0-3
4-7
Adjusted Mean
(SE)
P
Value
PTSD Symptoms
P
Value
OR
(95% CI)
P
Value
10.71 (0.59)
12.80 (0.71)
R vs I: .03
R vs D: .50
28.99 (1.62)
30.15 (4.34)
R vs I: .80
R vs D: .20
1.30 (0.64-2.66)
1.52 (0.68-3.36)
R vs I: .58
R vs D: .46
10.24 (0.60)
I vs D: .009
31.51 (1.71)
I vs D: .77
1.00
I vs D: .29
11.83 (1.09)
11.01 (0.50)
.40
12.16 (0.59)
10.23 (0.51)
,.001
13.58 (0.35)
10.12 (0.60)
,.001
9.22 (0.46)
9.32 (0.67)
8-11
12.49 (0.57)
12-16
15.87 (0.63)
,.001 (linear)
25.48 (4.86)
30.01 (1.46)
30.35 (2.15)
29.40 (1.81)
24.64 (3.45)
31.74 (1.14)
.35
.72
.047
1.68 (0.69-4.08)
1.00
2.10 (1.38-3.20)
1.00
2.09 (1.29-3.38)
1.00
37.59 (3.01)
1.00
32.19 (2.26)
0.65 (0.32-1.31)
25.64 (2.06)
20.07 (4.96)
.02 (linear)
1.49 (0.82-2.69)
.24
.001
.004
,.001 (linear)
3.54 (1.98-6.35)
*GHQ-28 indicates General Health Questionnaire-2810,11; MOS-20, Medical Outcomes Study13; PTSD, posttraumatic stress disorder; OR, odds ratio; and CI, confidence interval.
See the Methods section for a description of each screening tool. All P values are adjusted for location, sex, current employment status, age, marital status, education, indication of previous psychiatric illness, and indication of chronic illness.
Indicates change to not significant from univariate analysis.
575
established based on studies of the relationship between mental health and clinical measures of the probability of any
psychiatric disorder.13 Using the same
cutoff score for the Kosovo population
would result in an estimated prevalence of psychiatric disorder of 83.5% vs
13.2% in the US population.20 Further
clinical validation of the GHQ-28 and the
MOS-20 is under way to establish the
best thresholds for the Kosovar population. The estimated prevalence of PTSD
symptoms (17.1%) is somewhat lower
than the reported PTSD figures (26.3%)
for Bosnian refugees living in Croatia.4
The findings from the GHQ-28, MOS20, and HTQ confirm earlier anecdotal
reports that while the general health status of the Kosovo population remained
fairly stable, mental problems related to
the war situation are common. This is
in line with other findings in refugee
camps and war/conflict situations.3-7 No
baseline general mental health status
data from before the war are available
for Kosovo. However, in our survey, selfreporting of previous mental illness
(1.7%) correlated with findings in other
populations.29
We identified several subpopulations at risk for poor mental health status and social functioning and we also
attempted to identify mitigating factors. In general, Kosovar Albanians
younger than 35 years old, in good physical health, and without previous psychiatric illness appear to have been protected from war-related psychiatric
morbidity. Future research will have to
determine whether there are other protective factors that could be influenced
by policy (eg, adequate housing, social
and community support). Social functioning was significantly lower among the
population in rural areas; however, location did not seem to have the same effect on general mental health. It is possible that the extensive disruption of the
civic infrastructure in the rural areas
made it harder to function socially than
in cities, but closer family ties in these
areas mitigated mental health problems. Not unexpectedly, people with previous psychiatric illness had worse mental health outcomes, including higher
Until the psychological and social effects of the war and persecution in
Kosovo are evaluated over time, we
must exercise caution in basing future
predictions on the results of our survey. Follow-up studies and monitoring of mental health problems to determine long-term effects of multiple,
prolonged, and severe traumatic events
among the Kosovar Albanian population will provide more accurate data for
policy recommendations.
Author Affiliations: National Center for Environmental Health, International Emergency and Refugee Health
Branch (Dr Lopes Cardozo), National Center for Infectious Diseases, Division of Quarantine (Dr Vergara), and National Center for Environmental Health,
Environmental Hazards and Health Effects (Dr Gotway), Centers for Disease Control and Prevention, Atlanta, Ga; and Institute for Mental Health and Recovery, Pristina, Kosovo (Dr Agani).
Funding/Support: This study was supported by funds
from the Centers for Disease Control and Prevention.
Acknowledgment: We acknowledge the enormous
contribution and logistic support of Doctors of the World,
in particular Supriya Madhavan, who provided us with
invaluable insights into the Kosovo situation. We also
acknowledge the contributions of the interviewers, many
of whom themselves had been refugees or internally
displaced during the war, who made the data collection possible. We also acknowledge the contribution
of mental health staff from the Institute of Mental Health
and Recovery in Pristina, Kosovo. The Harvard Program in Refugee Trauma gave us invaluable advice, particularly by Richard Mollica, MD, MAR; James Lavelle,
MSW; and Keith McInnes, MS, who shared their extensive clinical and research expertise in this field.
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