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1a- fat
b- protein
c- connective tissue
d- muscle
e- A B
&
if a drug has the same active ingredient like other drug but not contain the same inactive ingredient this mean
2:a- Bioequivalent
b-pharmaceutical equivalent
c- pharmaceutical alternative
d- A,B
3-
A patient purchasing sublingual nitroglycerin tablets should be told to store the medication
:
a. in the refrigerator
.
b. in a plastic vial with a childproof cap
.
c. with the original cotton
.
d. in an amber glass bottle with a metal cap
.
e. in a warm, dry place
8-
a_phynetoin
b_disopyramide
c_propranolol
d_verapamil
e_propafenon
anti cancer derived from venca is
24_
a_cyclophosamide
b_flourouracil
c_doxurubcin
d_ cicplastin
which one used to trigeminal neuralgia
25- _
tegretol
26-
the solution contain 9ppm of NaCl the the concentration of the compound in the solution
a_0.9
b_.09
c_.009
d_.0009
e_.00009
process require CYP450
27:
a)OXIDATION
b)HYDROLYSIS
c)GLUCORONIDATION
d)DEAMINATION
e)SULFERATION
Adsorption , which is not true
28:
a) Chemical property
b) Physical property
c) Reversible
d) Irreversible
e) A + d
about steady state concentration during IV adminestration
30a_directly ptoportional to volume of distribution
b_inversly proportional to volume of distribution
c_directly ptoportional to infusion rate
d_ inversly proportional to total body clearance
e_ c d
&
which of the following decrease gastric emptying rate
31- _
a_ metoclopramid
b_ atropin
c_ hypothyrodism
d_a b
&
e_b c
&
one of following is not alpha 2 agonist
32:
a) Clonidine
alpha 1 agonist )) b) Alpha methyl noradrenaline
c) Guanfacine
d) Guanabenz
e) Guanethidine
about side effect of quinidine
33:
Cinchonism
about digitoxin , which is false
34:
a) Oral bioavailability 100%
b) Protein binding 95%
c) Half life is 7 days
d) Mainly hepatic metabolism by microsomal
--35- volatile substance given by inhalation:
a) Halothane
to compare between 2 drugs use
36:
a) Physical appearance
b) Weightif comparing bioequivalency))
c) Pharmacokinetic parametersif effect
)) d) Pharmacodynamic parameter
e) Taste
&
if we have asolvent costs 150 riyal/kg and its specific gravity =1.07 ,so the cost for 100
73- ml of the solvent is
?
16.05
74- which of the foll. drugs show most multidrug resistance
a)antibiotics
b)anticancer
c)a b
&
The following liquids are least likely to be miscible
75- .
:
A. polar + polar
B. non-polar + polar
C. non-polar + non-polar
D. all of the above will be miscible
E. Band C
At 25 C, benzoic acid is much more soluble in benzene (C6H6) than it is in water. In this situation benzoic acid could be considered to be
76:
A. Hydrophilic
B. Colloidal
C. Non-polar
D. Polar
E. Both A and D
The following properties are similar for both solutions and suspensions
77:
A. The components of both solutions and suspensions can be separated from each
other by physical processes
..
Solutions and suspensions are composed of two or more components
8.
.
C. Solute in the solutions and suspensions settle out over a period of time
.
D. Both A and B
E. Both Band C
Concerning COX-2 inhibitor, which is not true
78?
A. they have lower risk gastric adverse reactions than non-selective agents
B good evidence about their effectiveness in osteoarthritis
C. cardiac toxicity is a recent concern of this class of drugs
D. they are. usually administered once or twice daily
E. combination with non-selective agents provide additional benefit
In the treatment of the osteoporosis, which of the following is not correct
79:
A. alendronate should be taken in the morning 60 min before breakfast
B. calcium and vitamin 0 are essential
C. hormone replacement therapy (HRT) should be considered in all postmenopausal
patients with osteoporosis
D. outcome should be assessed with periodic bone density studies
E. raloxifene is selective estrogen modulator that is contraindicated in DVTpatients
Side effects of albuterol include which of the following
80?
A. Bradycardia
B. Tachycardia
C. Convulsion
D. Hypotension
E. Alopecia
,
Which of the following side effects is associated with the use of norepinephrine
81- .
:
A. Nausea and vomiting
.
B. Ischemic damage due to vasoconstriction and tissue hypoxia
.
C. Hypoglycemia due to increase insulin reiease
.
D. Skin rashes
.
E. Headache and constipation
.
the pharmacological property of amphetamine is
82:
A. Causes release of estrogen
.
B. Causes release of stored norepinephrine
.
C. Does not cross the blood brain barrier
.
D. Causes the release of stored acetylcholine
.
E. Metabolized by phosphodiesterase II
.
Which of the following statements describing first dose phenomenon that associated
83with prazosin is true
?.
A. A marked increase in the level of glucose following the initial dose of prazocin
.
B. A marked decrease in the level of glucose following the initial dose of prazocin
.
C. A marked increase in the level of cholesterol foilowing the initial dose of prazocin
.
D. A marked postural hypotension 30 to 90 minutes following the initial dose of prazocin
.
all the following diazoxide side effects except
84a-tachcardia
b-diuresis
c-hyperglyemia
d-hyperuricemia
e- hypotension
which one causes hypotension due to blockage of efferent limb baroreceptor reflex
85a- bretylium
b-phenytoin
c- ranitidine
d- amphetamine
e-isopreterinol
wich statment about radaition parameters or units is false
86a.Becquerel is the transformation (disintegration) rate of a radioactive substance
b.Gray (Absorbed dose) is a physical quantity which represents the energy imparted by radiation onto an absorbing material
.
c.Roentgen (Exposure) is a quantity that expresses the ability of radiation to ionize air and thereby create electric charges which can be collected
and measuredd
.
d.none of the above
*
thiopental is
87- )
?
a ) short acting barbiturates
b ) long acting barbiturates
c ) spinal anaesthesia
d ) antihistaminic
e ) antibiotic
which of the following is not macrolide antibiotic
88?
a ) erythromycin
b ) spiramycin
c ) chloramphenicol
d ) clarithromycin
e ) azithromycin
89 - 3 )
a)5
b ) 25
c ) 500
d ) 2500
e ) 25000
Very small molecule(1 part ) soluble in more than 10,000 part of water
94a- fairly soluble b- slightly soluble
C-immiscible d- miscible e- insoluble
Which one of the following cause hypertensive crisis if withdrawn suddenly
95Clonidine
hydrochlorothiazide
b-blocker
prazocin
which one is not effect of Nitroglycerin
96vasodilation
relax of biliay muscle
slow heart rate
taken sublingually
decrease blood pressure
drugs have different crystal structures so different in
97- 5a-polymorphism b-solubility c-crystalitis
d-drug form
which of these have intrinsic sympathomemtices effect
98:
a-labetlol b-timlol c--nidlol
d-Pindolol e-propanlol
99-
a-500 mcg
b-700 mcg
c-1500 mcg
most potent anti-inflammatory corticosteroid systemically is
101- :
a-cortisone
b-hydrocortisone
c-triamcinolone
d-prednisone
e- dexamethasone
suspension eye drop differ than ophthalmic solution in
102- :
a-less commonly used
c- decrease contact time of drug with eye
c- used for insoluble drugs
d- a c
&
cushing - like syndrome is due to
103a) adrenal hyperplasia b) adrenal hyporplasia
c) Hypothyroidism d) hyperthyroidism
Morphine causes respiratory depression by
104- a) depression of respiratory center in brain
b) activation of respiratory center in brain
c) depression of CTZ receptors center in brain
d) activation of CTZ receptors center in brain
Calcium-channel blockers mode of action
105a) increase the inward calcium to cells b) decrease the inward calcium to cells
which is (are) electromagnetic waves
106- ?????
a)X-ray b) Beta- ray c) Gama- ray d)a+c
107- -
Phenylepherine
e- 0.0230 m
113-
a-1.882
b-0.882
c-0.559
d-0.575
drug container contain 90 mg each tablet contain 0.75mg. how many doses
114?
doses
90 / 0.75 = 120
most described dosage solid form
115:
powder , tablet , soft capsule , hard capsule , both types of capsule
has 5-HT antagonist and H1 antihistamine effects
116Cyproheptadine
Dobutamine is used as
117:
a- Parasympathomimetic
b- In cardiac surgery
c- Hypotensive agent
d- All of the above
Controled released drug delivery depends on
118:
a- Body fluid interaction
b- Enzymatic reactions
c- Ready programmed no influece of the body fluid
&
d- Stomach PH
.
All of these are antichlonergic except
119:
a- Atropine sulphate
b- Hydroatropine
Mebeverine
d- Iprotropium bromide
e- Butrepium bromide
all these drugs used in amoebic dysentery exept
120metronidazole
diloxanid
gentamycin
tetracyclin
sol contain D5W another one contain D50W we want to prepare sol contain D15W its volume is 450ml
121how much ml we need of each sol
5% ---------------------------------- 35= (100ml)
15%
50% -------------------------------- (350ml)10
Terbutaline is used as
Antiasthmatic
Freeze drying is done by
Sublimation
.
Converting big fragments into small fragments is
Reduction
q.d.s=q.i.d=
>>>>>>>>
p.r------