Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Metabolic waste product removal (uric acid as well as urea) from the body
Electrolyte balance regulation (e.g. calcium, sodium and potassium)
Control of body water content and blood volume also known as
osmoregulation
Regulating blood PH and acid-base homeostasis
The Kidneys
Location: Located behind the peritoneal cavity on the posterior abdominal wall
and either side of the spine. The left kidney sits a bit higher than the right kidney
to accommodate the liver
Definition: A pair of organs in the dorsal region of the vertebrate abdominal
cavity, functioning to maintain proper water and electrolyte balance, regulate
acidbase concentration, and filter the blood
of metabolic wastes, which are then excreted as urine.
(http://www.medicinenet.com/script/main/art.asp?articlekey=4103 )
Main Function: The kidneys are the waste filtering and disposal system of the
body
Physical Description: Two reddish bean shaped organs that is about the size of a
fist
Significant Features and Functions:
The Bladder
Location: Located in the pelvis, just above and behind the pubic bone.
Definition: A hollow organ in the lower abdomen that stores urine.
(http://www.medicinenet.com/script/main/art.asp?articlekey=2472)
Main Function: Temporary storage reservoir for urine before eliminating it
Physical Description: A muscular sac, when empty, the bladder is about the size
and shape of a pear, the size varies due to the volume of urine within
Significant Features and Functions:
The wall of the bladder has four layers
The Ureters
Location: Each kidney has a ureter attached to it. The ureter is split into 2
locations, with the upper half in die abdomen and the lower half in the pelvic
area.
Definition: One of the two tubes that carry urine from the kidneys to the bladder.
Each ureter arises from a kidney, descends, and ends in the bladder.
(http://www.medicinenet.com/script/main/art.asp?articlekey=5909)
Main Function: To transport urine from the renal pelvis of the kidney to the
urinary bladder
Physical Description: Almost 12 inches in length, the ureter consists of a tube
with thick walls thats composed of a fibrous, a muscular and a mucus coat, all of
which are able to contract.
Significant Features and Functions:
The ureters walls consists out of muscles, that by contracting and relaxing forces
the urine away from the kidneys
The Ureters pass below the urinary bladder, thus allowing the compression from
the bladder to assist with the prevention of urine backflow. Should urine backflow
occur, the ureter as well as the urinary bladder may develop inflammation, which
could develop into a kidney infection.
The Urethra
Location: Passes from the bladder; - in females that it ends inferior to the clitoris
and superior to the vaginal opening, in males it ends at the tip of the penis
Definition: The tube through which urine moves from the bladder and out of the
body and that in men and male animals is also the means by which semen
leaves the body (http://www.merriam-webster.com/dictionary/urethra)
Main Function: To carry urine from the bladder emitting out of the body in both
males and female, however in addition to the aforementioned, the urethra in
males also to transport semen from the testes through the penis
Physical Description: A tubular structure that varies in length (depending
whether male of female); female 1.5 inches long, males 8 inches long
Significant Features and Functions:
The nephron is situated within the cortex with the tubule in part of the medulla.
The nephron consists of two major structures, the renal corpuscle and the
tubules. Within the renal corpuscle sits the glomerulus that leads into the
Bowmans capsule. The glomerulus is small ball-shaped structure composed of
capillary blood vessels. Basically like a sieve and anything bigger than the holes
will not to allow blood cells and proteins to pass through. From here the blood
flows through the peritubular capillaries, and the ultrafiltrate flows through the
tubule.
In the early parts of the tubule, almost all of the nutrients in the filtrate get
reabsorbed. These nutrients include glucose and amino acids and vitamins. Allot
of the sodium and water in the filtrate are reabsorbed and return to the blood.
However there are elements are secreted into the tubule along the way. Some of
the elements include metabolic wastes.
Aldosterone a hormone) assists the body to preserve or maintain the correct
sodium and water levels. ANP (atrial natriuretic peptide hormone) helps the body
get rid of excess water. By the time the filtrate enters the collecting duct, it has
been changed into urine. ADH (an antidiuretic hormone) works in the collecting
duct to regulate urine concentration.
The resulting urine passes from the renal tube through tubes called ureters and
into the bladder. The bladder is flexible and is used as storage until the urine is
allowed to pass through the urethra and out of the body.
The structure of the Kidney Nephron and Collecting duct is of such a nature that
it relates to the function it serves. Below is a table listing some of the structures
within the Kidney Nephron with a short description, structure (or composition)
and the function of the structures.
Name
Glomer
ulus
Description
A tiny ballshaped
structure
composed of
capillary blood
vessels..
Structure
Actively involved in the
filtration of plasma. The
capillaries have pores
that prohibits passage of
blood cells. The
Basement membrane
restricts passage of large
proteins.
Bowma
n's
Capsule
Thin-walled,
cup-shaped
structure that
surrounds the
glomerulus,
basically
catches the
bigger
substances
Function
The structure allows
waste products and
some water and salts
to pass from the blood
- as glucose or amino
acids, ions, peptides,
drugs and waste
products of organic
metabolism such as
creatinine and urea
Filtration in order to
eliminate organic
wastes, water and
additional inorganic
salts.
that the
glomerulus
could not filter
Proxima
l
convolu
ted
tubule
(PCT)
Longest part
of the renal
tubule - has a
simple
tall cuboidal
epithelium, wi
th a brush
border
(microvilli).
Loop of
Henle
long, Ushaped
portion of the
tubule
Distal
convolu
ted
tubule
The final
segment of
the nephron,
and it is found
Epithelial cells
are cuboidal, with very
few microvilli
Regulates the pH of
the filtrate and it is
also responsible for
secreting organic
acids, such as
creatinine and other
bases, into the filtrate.
(DCT)
Collecti
ng duct.
in the renal
cortex
Twisting tube
that collects
urine from the
nephrons and
moves it into
the renal
pelvis and
ureters
In conclusion, the excretory system is an important way for the human body to
remove waste. This process could be summarised in three essential steps:
Filtration blood filters through the kidneys where most of the water, ions,
urea and sugar are moved to the tubules
Selective reabsorption beneficial elements are reabsorbed back into the
blood from the tubules. The amount of water in the blood is regulated here
to maintain it at a constant rate. This is known as osmoregulation.
Excretion of waste urine (that consists of excess water, urea and ions)
are moved from the kidneys to the urinary bladder and released from the
body.
References
Shaw, L (2005) Anatomy & Physiology Access to HE, Cengage, Hampshire
Rea-Dupree, J and DuPree, P (2007) Anatomy & Physiology workbook for
Dummies, Wiley, Hoboken
Boyle, M and Indge, B and Senior, K (1999) Human Biology 1st Ed.
HarperCollins, London
Dr Peters, M (2013) BMA Illustrated Medical Dictionary, 3rd Ed, Dorling
Kindersley, London
Waugh, A and Grant, A (2014) Ross and Wilson Anatomy and Physiology in
Health and Illness, 12th Ed, Northampton shire
Internet Source
Glomerular Filtration. Boundless Anatomy and Physiology. Available at
https://www.boundless.com/physiology/textbooks/boundless-anatomy-andphysiology-textbook/the-urinary-system-25/kidney-physiology-240/glomerularfiltration-1172-1776/ accessed on 14 February 2015