CLINICAL STUDY REPORT

Study title
PREvalence of peripheral arterial disease in acute coronary Syndrome
patiETNs
Investigator(s): BALAN ADRIAN (seria VI, grupa 49)
Data set: 6002
Objectives:
Primary:
To evaluate the prevalence of Peripheral Arterial Disease (PAD) in patients
admitted in hospital with diagnosis of ACS or outpatients after an ACS (within last
6 months), ambulatory checked.

Secondary:
To indentify the Main Clinical Variables associated with a higher risk of PAD among
this population
To evaluate the therapeutic management of these patients
To train Cardiologists to measure Ankle / Brachial Index (ABI) in order to improve
diagnosis of PAD

Methodology: open-label, non-randomized, national, multicentric, prospective, noninterventional study

Number of patients/subjects: 100

Evaluated:
ABI (Cut-off for PAD 0,9)
Epidemiological data:
atherotrombotic risk factors
cardiovascular previous events
treatments prescribed at visit 1 (by therapeutic class)

Diagnosis and criteria for inclusion:

Inclusion Criteria: patients > 40 years admitted in hospital with diagnosis of Acute
Coronary Syndrome or outpatients after an ACS (within last 6 months), ambulatory
checked; informed consent singned
Exclusion Criteria: patients < 40 years; patients who did not sign the informed
consent form; patients enrolled in other studies

Criteria for evaluation:

Will be collected: demographic data of the patient, cardiovascular risk factors,

personal history of cardiovascular diseases, clinical data, diagnosis of coronary disease,
Ankle-Brachial Index (ABI), antiplatelet treatment recommended at baseline.

Sumary:
Population studied: 100 patients, with the following gender distribution: 64 % male and
36 % female and with mean age of 65.40 years ( 64.80 years in male group, respective
66.47 years in female one).
Cardiovascular risk factors
Cardiovascular risk factors
Hypertension

Diabetes mellitus

Smoking / History of smoking

Dyslipemia

Family history of
cardiovascular disease

Count

Column N %

No

33

33%

Yes

77

77%

No

62

62%

Yes

38

38%

No

58

58%

Yes

42

42%

No

10

10%

Yes

90

90%

No

39

39%

Yes

61

61%

Personal history of cardiovascular disease

73 of these patients (73 %) were having history of coronary disease (angina pectoris,
myocardial infarction etc), 18 patients ( 18 %) history of cerebrovascular disease (stroke,
TIA, carotid stenosis) and 33 of them ( 33 %) history of peripheral arterial disease.
Clinical data at baseline
Mean weight was 81.29 kg (81.27 kg in the male group and 81.33 kg in the female one),
mean heigh 170.24 cm (168.75 cm in the male group and 172.89 cm in the female one)
and mean waist 97.66 cm ( 96.68 cm in the male group, respective 99.43 cm in the
female one).

Clinical data
N

SBP

DBP

Heart rate

Valid

90

65

45

Missing

10

35

55

Mean value

141.33

82.41

74.50

Diagnosis in the coronary disease

74 of the patients ( 74 %) were diagnosed with angina pectoris and 26 of them ( 26
%) with myocardial infarction. Mean history of disease was