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9781284036015
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Basic Biostatistics
Biodiesel Production Using
Bioinformatics for Beginners
Biological Identification: D
Biomolecular Electronics: Bio
Biostatistics: The Bare Essent
Biotechnology Entrepreneurs
Exploring Bioinformatics 2E
The Fact Of The Embryo: A D
Basic Molecular Protocols In
Biological Safety
Biology N Therapeutic Poten
From Molecules to Networks:
Handbook Of Biological Sci
Homology, Genes, And Evolut
Imaging Life: Biological Sys
Life's Blueprint
Looking Inside the Brain: T
Neural Stem Cells In Hypoxi
Neuroscience And Multilingu
Plasma Membrane Domains
Presenting Scientific Researc
Quantum Effects in Biology
The Cognitive Neurosciences
The Future of the Brain: Ess
Transgenerational Epigenetic
Unnatural Selection
Science Unshackled
Epigenetics
Epigenetics in Psychiatry
Progress in Molecular Biolog
Cellular Connectomics:Recon
Computational Neuroscience
Neuroimaging Atlas of the H
Omega-3 Fatty Acids in Brai
Rosenberg's Molecular and Ge
The Stimulated Brain
Making Space
Recent Advances in Systems
Binding, Transport and Storag
Cell Cycle
Cell Engineering Second Edi
Cell Structure & Function (F
Cellular Mechanotransduction
Extracellular Matrix
Ganglion Cells: Morphology,
Growth in Length: Embryolog
Lewin's CELLS 3E
Methods in Cell Biology, Vo
Micropatterning In Cell Biolo
Micropatterning in Cell Biol
Nuclear pore complexes and
Oxidative Stress: Causes, Rol
Planar Cell Polarity
Sertoli Cell Biology
Stem Cells In Development A
Stem Cells: Cellular & Drug
The Stellate Cell (Vitamin AIn Search of Cell History
Cellular Endocrinology in He
9780128011218
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Nanoparticle-based approaches
Proteomics in Biomedicine a
Regulatory Affairs for Bioma
Semiconducting Silicon Nano
Switchable and Responsive Su
Applications of Modern Phys
Progress in Medicinal Chemi
Translational Systems Biolog
Materials and Strategies for
Soft Nanoparticles for Biome
Pattern Recognition and Sign
Human Brain Pathways
Metabolomics and Systems B
Cord Blood Stem Cells and R
Brain Transcriptome
Molecular Neuroscience: A L
Modulation of Sleep by Obesi
The Mitochondrion in Aging
Mark's Essentials of Medical
Introductory Immunology
Asperger Syndrome (Autism
Essential Neuroscience
AOSpine Masters Series Vol
Brain Metastases from Prima
Cancer Cell Signaling: Targe
Cancer Therapy: Prescribing
Cancer, Autism And Their Ep
Cancer:Oxidative Stress And
Catching Cancer: The Quest F
Contemporary Transoral Sur
Debating Cancer
Electroporation-based therapi
Emerging Applications of Mo
Endometrial Cancer: A Compr
Evolution by Tumor Neofuncti
Fighting Lung Cancer through
Flow Cytometric Analysis o
Free Radicals: The Role of A
Gastric Cancer: Risk Factors
Gliomas: Classification, Sym
Global Perspectives On Cance
Handbook of Targeted Cance
Horizons In Cancer Research
Human Papillomavirus: Bench
Immunological Pathogenesis
Innovative Brain Tumor Ther
Leiomyosarcoma: Risk Factors
Medulloblastoma Book, The
Molecular Diagnostics and T
Multiple Myeloma: Risk Fact
Neoplastic Mimics In Gastroi
Neuro-Oncology: The Essenti
Palliative Care To The Cance
Pandora'S Dna
Paraneoplastic Syndromes:
Pathophysiology Of Pheoch
Successes And Limitations O
The Cancer Revolution: Integ
Therapy for Hepatocellular C
World Cancer Report 2014
Autophagy: Cancer, Other Pat
9780124055285
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215.00
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Cancer research is at a crossroads. traditionally, cancer ha
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Aminoffs neurology and general medicine is the standard
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our healthy breasts and ovaries if you thought it might save your life? that's not a theoretical question for journalist lizzie stark's relatives, who grapple with the horrific
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esents original study results on the leading edge of neuroscience research. each article has been carefully selected in an attempt to present substantial research results a
ined as excessive sweat production beyond requirements for temperature regulation. it can be idiopathic, secondary to other systemic conditions such as endocrine or a
clinical reference on central nervous system infections is now in its thoroughly revised, updated Third Edition. More than 70 leading experts provide comprehensive, c
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ms) is generally understood to be an inflammatory autoimmune disease of the central nervous system. while we still are not certain of the root cause of ms, research res
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volves several parts of the body or the complete system. neurologic aspects of systemic disease, a two-part volume in the handbook of clinical neurology series, focuses
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disorder may be seen as a gateway condition from normalcy to pathology with blurred boundaries towards several concurrent disorders. this anxiety illness is responsi
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gic system is one of the most studied neurotransmitter systems in the central nervous system. Since the original studies of Dahlstrm and Fuxe in the mid-60s, when th
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erials science approach, this textEnglish
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e future, micro-scale technology seeks to fuse revolutionary concepts in science and engineering and then translate it into reality. Nanotechnology is an interdisciplina
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ineering of the cell surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phen
range electrochemical nanosensors, including the use of carbon nanotubes, glucose nanosensors, chemiresistor sensors using metal oxides and nanoparticles. part two
semi-precious metals have been used in medicine for many years. the properties of these metals and their alloys makes them suitable for an increasing number of med
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tells the researcher on a scientific level. these explanations describe relevant controls, troubleshooting, and reaction components for some of the most widely used neu
ost fundamental yet challenging concepts in evolutionary biology. this groundbreaking book provides the first
ve set of reviews covering such topics as the mechanisms of pluripotency in vivo and in vitro, hematopoietic stem cell development, intestinal stem cells and their defi
cted in an attempt to present substantial research results across a broad spectrum. in this continuing series compilation, the authors present and discuss varied topical d
expertise devoted to the theme of 'life'. the book forges connections between art, science and the humanities in a vibrant and thought-provoking collection that exposes
s. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation to genomics, pro
ition includes more bioinformatics-specific content and a new chapter on good software engineering practices to help people working in teams.
ribe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that ar
aduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous
aria vaccine development; liposomal delivery of antimicrobial agents in advances in liposome research; trends on microfluidic liposome production through hydrodyn
of microbes including photosynthetic organisms. this book may be useful for undergraduate and graduate students as well as researchers in the related area to understa
vity, and practical application of extracellular glycolipids of yeast. this book brings much-needed clarity to the complex topic of glycolipids and streamlines the rather
hemical sensing and manipulation. This book is concerned with the ingredients for a polymer-based platform which is able to culture and pattern life cells for a suffici
nding of mechanisms involved in skin physiology. The book is structured around some skin properties and functions, including optical and biomechanical properties, s
brain. a broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the
developing area. Continuing with the broad base style of both current molecular and traditional biotechnology, chapters have been updated to reflect current interest an
understanding how a technology works.-engineering principles are addressed, but in such a way that an instructor can skip the sections without hurting course conten
xtile, detergent, food and animal feed. the book carries up to date information and presents a wider perspective scope wise in the field of enzymology. the book would
ow being used increasingly for biomaterials and tissue engineering applications. this book discusses the properties and applications of silk for medical purposes.
explain our observations from deep subsurface ecosystems it is necessary to develop interdisciplinary approaches, ranging from microbiology and geochemistry to ph
and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction
el complex data. an expanding volume of biological data of various types, the so-called 'omics', is in need of accurate and efficient methods for modelling and pgms ar
e a host organism in order to fulfill its vital functions because it lacks the biochemical organizations that replication requires. This book discusses several topics that in
encourage tissue growth, further improving the strength of the implant. this book provides readers with a comprehensive review of biomedical foams.
epair and regeneration of the heart.
f this active and fast-changing field. drs. abul k. abbas, andrew h. lichtman, and shiv pillai present key updates in this new edition to cover the latest developments in a
challenges it presents for both conventional and alternative therapies. In his exploration of a productive reconciliation in their conflicting approaches, Haller maintains
undamental function. written by two leading brain scientists, it is an important contribution to our understanding of the evolution and functioning of the human brain.
h are the contractile machinery consisting of interactive myofilaments. since the abundance of troponin subunit proteins in myocytes and their muscle-specific expressi
ding a systematic overview of key aspects to be considered in the formulation of nanoparticulate systems for drug delivery to severe diseases. It also analyses drawbac
last centuryincluding X-rays, radiation treatment, laser surgery, high-resolution ultrasound scans, computerize
a distinct resource for surgeons and oncologists interested in transoral surgery. This text gives readers current, thoroughly illustrated, and data-driven information on a
cancer gene mutations is the key, and the identification of common gene mutations has been considered to be essential for diagnosis and treatment. despite extensive re
, including melanomas, sarcomas, superficial extreme melanoma, chest wall breast carcinoma, and colorectal cancers-extensive study of a number of cell lines, includ
early-stage and curable with loco-regional therapies. metastatic and/or recurrent disease still remains a therapeutic challenge and clearly represents an unmet medical n
ock developed after surgery. Patients without signs of infectious complications and symptoms of organ failure, as well as a group of healthy donors, were considered a
of medulloblastoma as a term and a distinct entity in nosology, and then it explores in-depth the diagnosis, genetics, neurosurgical and oncological management of med
a cells in the bone marrow (bm). mm is associated with lytic bone lesions, anemia, immunodeficiency, and renal impairment. multiple myeloma accounts for more than
h issue that should be integrated into the mainstream of cancer care as well as other life-threatening diseases. nowadays, it is recognized as a human right issue that pa
ark's relatives, who grapple with the horrific legacy of cancer built into the family dna. it is a brca
of cancer. These conditions are not directly caused by tumor metastasis, but rather the malignancies produce hormones and other proteins which act to disrupt the bod
ons About Systemic Therapy Were Largely Based On The Performance Status Of A Patient, Oncologists Today Also Take Into Account The Pathological And Molecul
r have had, cancer or indeed those wishing to avoid cancer.
neurological practice and general medicine. as neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking ge
t a wide range of symptoms and severities. Once seizures are well-controlled without impeding side effects or co-morbidities, patients with epilepsy can participate in
mpt to present substantial research results across a broad spectrum. Included in this volume are amygdala-induced modulation of cognitive brain structures; plasticity
mpt to present substantial research results across a broad spectrum. included in this volume are molecular mechanisms integrating adenylyl cyclase responsiveness to m
r systemic conditions such as endocrine or autonomic dysfunction, as well as a side effect to medication. an estimated 7.8 million americans suffer from hyperhidrosis
70 leading experts provide comprehensive, current information on all infectionsboth neural-specific and systemicthat involve the central nervous system.This edit
al brain function. This book provides an overview of the role of metabotropic glutamate receptors (mGluRs) in basic brain functioning, such as autonomic regulation,
certain of the root cause of ms, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. ms cau
al and cognitive functions. Under physiological conditions, only a few immune cells, such as: macrophages, lymphocytes and dendritic cells can cross the blood-brain
ndbook of clinical neurology series, focuses on the specific neurologic aspects of systemic disease. part 1 includes detailed coverage of cardiovascular disease, pulmo
ndbook of clinical neurology series, focuses on the specific neurologic aspects of systemic disease.part 2 includes coverage of gastrointestinal and hepatobiliary, endo
pects of systemic disease. part 3 includes coverage of oncologic disorders, organ transplantation, infectious diseases, tropical neurology, pregnancy, neuroanesthesia an
me to be transformed into the specialised physicians we now call neurologists. relying entirely upon hitherto unseen primary sources drawn from archives across britain
what we know about neural networks. how the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and
ent disorders. this anxiety illness is responsible for psychological suffering and personal dysfunction in a considerable proportion of individuals in the general populati
eld Review The Basic Principles Of Proteomics And Metabolomics And Propose The New Directions To Be Followed In Molecular Psychiatry. The Chapters Divided
Dahlstrm and Fuxe in the mid-60s, when they mapped the pattern of monoaminergic neurons using formaldehyde-induced flourescence technique developed by Falck
ed ultrasound for stimulation of somatosensory, hearing and other neural structures. It is well-known that focused ultrasound is used widely for local ablation of disease
And Managed And How Treatments Are Monitored. In This Volume The Latest Developments And Findings Are Presented By Experts In Their Respective Fields. Aft
eality. Nanotechnology is an interdisciplinary field that aims to connect what is seen with the naked eye and what is unseen on the molecular level. Diverse Applicatio
anipulate or augment cell functions and phenotypes. the book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, includi
ng metal oxides and nanoparticles. part two discusses spectrographic nanosensors such as surface-enhanced raman scattering (sers) nanoparticle sensors.
m suitable for an increasing number of medical applications. this book provides readers with a useful review of this group of materials' unique properties and applicati
onents for some of the most widely used neuroscience protocols that remain difficult for many neuroscientists to implement successfully. having this additional inform
elopment, intestinal stem cells and their defining niche, epithelial stem cells in adult skin, the mammary stem cell hierarchy, satellite cells, neural stem cells of the hipp
authors present and discuss varied topical data such as the s allele of the serotonin transporter and its lack of association with major depression in veterans; effects o
d thought-provoking collection that exposes both conventional and unconventional views on the meaning of life, the enigmatic boundaries between the living and the d
, and infection, in relation to genomics, proteomics, and transcriptomics. The topic of companion diagnostics is also covered.
le working in teams.
ate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mec
idic liposome production through hydrodynamic flow-focusing and microdroplet techniques for gene delivery applications; liposomes as important drug carriers in can
as researchers in the related area to understand the current status and present an overview of the whole process. this may also help researchers to see the limiting proce
pic of glycolipids and streamlines the rather confusing terminology used for glycolipids. it also provides a wealth of modern data on their composition, structure and pr
to culture and pattern life cells for a sufficient period of time, enables the integration of photonic devices, and provides means to integrate electronic readout.
ding optical and biomechanical properties, skin barrier function, and homeostasis, covered through several chapters describing either biological or physical models at d
molecular machinery that contributes to the brain's ability to maintain information across time. memory systems in the prefrontal cortex, hippocampus and amygdala a
ve been updated to reflect current interest and include new areas such as stem cell technology and important areas in drug discovery such as IP and patents. By present
p the sections without hurting course content-the author has been involved with many biotechnologies through his own direct research experiences. The text is more th
modern trends such as pharmacogenomics, evaluation of gene expression, recombinant proteins from methylotrophic yeast, identification of novel fermentation inhibito
in the field of enzymology. the book would be advantageous not only for undergraduate, pg and phd students but also to non-specialists who may acquaint themselves
from microbiology and geochemistry to physics and modeling. this volume will be of high interest to biologists, chemists and earth scientists all working on the deep
d a concise but comprehensive introduction to immunology. the authors bring clarity and readability to their audience, offering a complete survey of the most fundamen
fficient methods for modelling and pgms are expected to have a prominent role to play.
s. This book discusses several topics that include viral infections in obstetrics and gynecology; the management of HIV infection by Chinese medicine; antiviral activi
edition to cover the latest developments in antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial int
eir conflicting approaches, Haller maintains a healthy, scientific skepticism but still finds promise in some complementary and alternative (CAM ) therapies. The place
to severe diseases. It also analyses drawbacks arising from the use of conventional drug nanocarriers-recent engineering approaches in nanoparticle synthesis have fac
illustrated, and data-driven information on all aspects of transoral surgery. The authors are pioneers in the field, having performed thousands of transoral surgery cases
diagnosis and treatment. despite extensive research efforts and accumulated knowledge on cancer genes and pathways, the clinical benefits of this traditional approach
nsive study of a number of cell lines, including human breast cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irrever
ge and clearly represents an unmet medical need. substantial progress has been made over the last decade in different fields of gynecologic oncology that has translated
group of healthy donors, were considered as references. The comparative analysis of blood parameters that characterized humoral and cell immunity (concentrations o
urgical and oncological management of medulloblastoma patients, their outcome, and long-term complications. Also discussed are novel therapies and next generation
t. multiple myeloma accounts for more than 10% of all hematologic malignancies and about 1% of all cancers. multiple myeloma remains mostly incurable despite co
is recognized as a human right issue that patients and families have the right to receive this care. the who defined palliative care as the active total care of the patient's
d other proteins which act to disrupt the bodys homeostasis, thereby causing symptoms. The neurological complications of PNS are the result of an immune response
nto Account The Pathological And Molecular Characteristics Of The PatientS Tumor. Targeting Specific Molecular Pathways Important For Tumorigenesis Has Beco
nce provides an authoritative tool linking general medical conditions to specific neurological issues and disorders. this is also a valuable tool for the general practition
es, patients with epilepsy can participate in various social activities and can maintain good quality of life. In order to achieve the condition, there are emerging new ant
tion of cognitive brain structures; plasticity and pathology of dentritic intrinsic excitability; the neurotoxic effects of heavy metals; fundamental mechanisms of glutam
grating adenylyl cyclase responsiveness to metabolic control on long term emotional memory and associated disorders; homeostatic synaptic plasticity; reorganization
million americans suffer from hyperhidrosis with up to 1.3 million reporting severe disease. affected patients can experience limitations in occupational and social circu
nvolve the central nervous system.This edition includes new information on botulinum toxin as a biological weapon and a therapeutic agent, neurologic effects of viru
functioning, such as autonomic regulation, synaptic plasticity, and learning and memory. Also provided are up-to-date summaries of recent progress towards identifyin
enes seem the most probable targets. ms causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal d
nd dendritic cells can cross the blood-brain barrier and gain access to neural tissue. For many years, these findings supported the notion that the brain was an immunol
coverage of cardiovascular disease, pulmonary diseases, renal diseases, and rheumatologic and musculoskeletal disease. each chapter provides a complete introductio
e of gastrointestinal and hepatobiliary, endocrinologic, and metabolic diseases, as well as nutritional, environmental, and hematologic disorders. each chapter provides
al neurology, pregnancy, neuroanesthesia and other diseases and disorders. each chapter provides a complete introduction to the neurologic aspect and provides the be
y sources drawn from archives across britain, europe and north america, this book analyses the emergence of neurology in the context of the development of modern m
d via study of neuronal network control and network interactions. large networks can undergo major functional changes, resulting in substantially different brain functio
ortion of individuals in the general population. since its original definition in the dsm-iii (1980), the clinical and scientific interest in generalized anxiety disorder has g
Molecular Psychiatry. The Chapters Divided Into Two Sections Schizophrenia/Psychotic Disorders And Mood Disorders Deal With Findings In Diverse Tissues Fro
flourescence technique developed by Falck and Hillarp, the distribution and the biological roles of catecholamines have been in the center of interest. It is clear now th
d is used widely for local ablation of diseased or damaged biological tissues and has become one of the most popular, safe and effective methods for application in me
d By Experts In Their Respective Fields. After A Short Introduction Covering The Available Equipment And The Basic Techniques, The Imaging Features Of Various P
n on the molecular level. Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering examines the strengths and future potential of micro-sc
nical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. written by leaders in the field, it covers numerous cell
ng (sers) nanoparticle sensors.
t successfully. having this additional information will help researchers ensure that their experiments work the first time, and will also minimize the time spent working
, satellite cells, neural stem cells of the hippocampus, lung stem and progenitor cells in tissue homeostasis and disease, spermatogonial stem cell functions in physiolo
with major depression in veterans; effects of regular versus special school placement in students with down syndrome; the biology of telomeres in multipotential strom
atic boundaries between the living and the dead, and what may or may not follow afterwards. this collection arises from the darwin college lecture series of 2012 and i
key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization
liposomes as important drug carriers in cancer therapy; liposome application in the veterinary field; and design of liposomes with a pH-sensitive fluorescent dye and g
so help researchers to see the limiting process and promote research toward creating innovation based on the knowledge gained from this book.
n data on their composition, structure and properties, biosynthetic pathways, methods of isolation and identification, antifungal activity, and mechanisms of action.stud
rontal cortex, hippocampus and amygdala are considered as well. in addition, the volume covers recent contributions to our understanding of memory from in vivo im
discovery such as IP and patents. By presenting information in an easily assimilated form, this book makes an ideal undergraduate text for students of biology and chem
ct research experiences. The text is more than a compendium of information - it is an integrated work written by an author who has experienced first-hand the nuances
identification of novel fermentation inhibitors of bioethanol production, and polyhydroxyalkanoate-based biomaterials. The book highlights the practical utility of bio
n-specialists who may acquaint themselves with this rapidly growing field. we feel extremely proud in recommending this book as ideal reading for any of the above s
ing a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subjects fascinating appeal.the content of this new edi
ection by Chinese medicine; antiviral activity of lactoferrin; and antiviral effects of phytochemicals of the Mediterranean medicinal plants. (Imprint: Nova Biomedical
munity, cytokines, leukocyte-endothelial interaction, and more. with additional online features, this is an ideal resource for medical, graduate and undergraduate studen
and alternative (CAM ) therapies. The placebo forms the central focus of the book, as Haller elucidates the latest findings on how new research about the placebo effec
markers for the clinical diagnosis of acute myocardial infarction and other heart and muscle injuries. intensive research from protein structure to genetic diversity to po
proaches in nanoparticle synthesis have facilitated increasingly efficient delivery of the drug dose to the site of action. Here, special insight will be gained on the intro
formed thousands of transoral surgery cases and publishing and lecturing extensively on the subject.Opening with the history of transoral surgery, the book goes on to
clinical benefits of this traditional approach have been limited. recently, cancer genome sequencing has revealed an extensive amount of genetic heterogeneity where th
ast cancer using both reversible and irreversible electroporation techniques-in vitro study of delivery of various commonly prescribed/administered breast cancer chem
of gynecologic oncology that has translated into a better understanding of the biology and clinical behavior of endometrial cancer and its management. hence, this mo
umoral and cell immunity (concentrations of cytokines and their receptors, immunoglobulins, lipopolysaccharide and other active biomolecules) has been performed. A
ssed are novel therapies and next generation clinical trials. This landmark text is written by leading authorities in research and treatment of medulloblastoma. It provide
yeloma remains mostly incurable despite conventional intensive high dose chemotherapy followed by hematopoietic stem cell transplant. the costs associated with mul
care as the active total care of the patient's body, mind and spirit; whereby health care providers need to evaluate and alleviate the patient's physical, psychological an
PNS are the result of an immune response to tumor antigens. PNS have been associated with a variety of cancers, such as genitourinary, ovarian, and breast, but are m
ays Important For Tumorigenesis Has Become The Preferred Way Of Treatment For Many Types Of Malignancies. With These Advances Come New Challenges Inclu
lso a valuable tool for the general practitioner seeking to understand the neurological aspects of their medical practice. completely revised with new chapters covering
ve the condition, there are emerging new antiepileptic drugs with sufficient efficacy to both partial and generalized seizures, with minimum adverse events, applicable t
metals; fundamental mechanisms of glutamate neurotoxity; dendritic morphology and connectivity in the medial amygdala; cultured adult dorsal root ganglion neuron
meostatic synaptic plasticity; reorganization of elementary functions (ref) after brain injury and in the intact brain; the effects of acoustic stimulation on comatose patie
e limitations in occupational and social circumstances. as a result, patients with hyperhidrosis often experience decreased physical and emotional wellbeing, difficulty
therapeutic agent, neurologic effects of viruses causing hemorrhagic fevers, and infections that have recently become more prevalent or been found in new geographic
maries of recent progress towards identifying how mGluRs both mediate and represent novel pharmacotherapeutic targets for the treatment of various neurological and
generation, oligodendrocyte death, axonal damage, and gliosis. over the past five years ongoing research has greatly expanded our understanding of the pathogenesis o
ed the notion that the brain was an immunologically privileged organ. To date, increasing evidence strongly challenges this conjecture. In fact, neuroinflammation trigg
ach chapter provides a complete introduction to the neurologic aspect and provides best known diagnostic and treatment practices. the collection is a valuable and trus
ematologic disorders. each chapter provides a complete introduction to the neurologic aspect and provides the best known diagnostic and treatment practices. the colle
o the neurologic aspect and provides the best known diagnostic and treatment practices. the collection will be a valuable and trusted resource for clinical neurologists,
he context of the development of modern medicine in britain. the neurologists thus surveys the patterns of change and modernisation that influenced british medical cu
ulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. with chapters authored by experts in each topic, this
interest in generalized anxiety disorder has grown, becoming a challenge for researchers and practitioners nowadays. this book provides a modern viewpoint with intri
Deal With Findings In Diverse Tissues From Human And Preclinical Models In Order To Unravel The Biology And Biochemistry Behind The Establishment And Co
en in the center of interest. It is clear now that catecholaminergic transmission not only plays a pivotal role in the modulation of stress response, but is also involved in
and effective methods for application in medicine amongst existing physical technologies. The content of this book is related with completely different field of investig
hniques, The Imaging Features Of Various Pathological Findings In Retinal Diseases Are Presented. The Topics Cover The Outer Layers Including New Modalities Fo
he strengths and future potential of micro-scale technologies in a variety of industries. Highlighting the benefits, shortcomings, and emerging perspectives in the applic
leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosens
d will also minimize the time spent working on a technique only to discover that the problem was them, and not their materials.
rmatogonial stem cell functions in physiological and pathological conditions, the origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells,
biology of telomeres in multipotential stromal cells; genetic diversity of human and animal papillomaviruses; telomere length in lymphoid malignancies; telomerase an
e darwin college lecture series of 2012 and includes contributions from eight distinguished scholars, all of whom are held in esteem not only for their research, but also
onal modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathw
ngal activity, and mechanisms of action.studies of extracellular glycolipids of yeast now draw the attention of researchers in life science and biotechnology due to num
r understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies.
aduate text for students of biology and chemistry, as well as to postgraduates.
who has experienced first-hand the nuances associated with many of the major biotechnologies of general interest today.-intellectual property issues are discussed-the
e book highlights the practical utility of biotechnology and bioinformatics for bioenergy, production of high value biochemicals, modeling molecular interactions, drug
book as ideal reading for any of the above students engaged in basic and applied research. any library, industrial and academic platforms strongly suits this book as it i
scinating appeal.the content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. the superb
medical, graduate and undergraduate students of immunology who need a clear, introductory text for immunology courses.
n how new research about the placebo effect might lead to a more robust medical practice including both the objectivity of evidence-based medicine and the subjectiv
m protein structure to genetic diversity to posttranslational modification and pathological mutations has comprehensively established the molecular structure of troponi
e, special insight will be gained on the introduction of passive and active targeting concepts in the engineering of such nanoplatforms to gain control of their biologica
ry of transoral surgery, the book goes on to address endoscopic anatomy, general techniques, as well as tips for analysis and pathologic considerations, and provides co
ve amount of genetic heterogeneity where the long-expected common mutation drivers have been difficult, if not impossible, to identify. these realities ultimately chall
prescribed/administered breast cancer chemo and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen-discusses electrical properties of cance
cancer and its management. hence, this monograph provides a current overview of endometrial cancer spanning from its clinical epidemiology to molecular cancer th
active biomolecules) has been performed. An estimation of diagnostic and prognostic significances of these parameters has been performed as well. In the final chapt
nd treatment of medulloblastoma. It provides information based on clinical trials, major clinical series, and the outstanding experience and knowledge of the authors. I
ell transplant. the costs associated with multiple myeloma are among the highest. this book discusses the diagnosis of multiple myeloma along with the risk factors inv
viate the patient's physical, psychological and social distress. such care encompasses a broad, multidisciplinary approach that includes both the family and the commun
genitourinary, ovarian, and breast, but are most commonly associated with neuroendocrine tumors. These syndromes can even occur before the primary tumor is ident
hese Advances Come New Challenges Including The Optimization Of Therapy, Recognizing And Dealing With Side Effects And, Importantly, The Development Of Re
mpletely revised with new chapters covering metastatic disease, bladder disease, psychogenic disorders, dementia, and pre-operative and post-operative care of patients
, with minimum adverse events, applicable to both adults and children, and used as monotherapy or add-on therapy. Sulfonamide drugs have been originally developed
; cultured adult dorsal root ganglion neurons; cognitive function with diabetes mellitus; and the posterdorsal medial amygdala, emotion and the sexually dimorphic soc
ts of acoustic stimulation on comatose patients; the splitting of the brain; the role of mineralocorticoid receptors in major depressive disorder; betaine in the brain; clin
hysical and emotional wellbeing, difficulty in personal relationships, and can suffer from social stigmatization. this book discusses several different causes of hyperhid
prevalent or been found in new geographic locations. The updated coverage of therapeutics includes AIDS/HIV medications and other antiviral drugs, new antifungal
for the treatment of various neurological and neuropsychiatric disorders, such as depression, anxiety, schizophrenia, amyloidogenic disorders and substance abuse. (No
ded our understanding of the pathogenesis of ms, detailed insight into the epidemiology and genetic factors related to ms, the introduction of new technologies and test
conjecture. In fact, neuroinflammation triggers a significant infiltration of immune cells into the cerebral parenchyma. The infiltration of inflammatory cells is accomp
ractices. the collection is a valuable and trusted resource for clinical neurologists, research neurologists, neuroscientists, and general medical professionals; a first stop
diagnostic and treatment practices. the collection is a valuable and trusted resource for clinical neurologists, research neurologists, neuroscientists, and general medical
nd trusted resource for clinical neurologists, research neurologists and neuroscientists and general medical professionals as a first stop for a comprehensive and focused
ernisation that influenced british medical culture throughout the nineteenth and twentieth centuries. in so doing, it ultimately seeks an account of how neurological kno
pters authored by experts in each topic, this book advances the understanding of:how the brain carries out important tasks via networks how these networks interact in
ook provides a modern viewpoint with intriguing insights on relevant topics, including historical frameworks, epidemiology, basic neurobiological sciences, clinical pr
hemistry Behind The Establishment And Course Of These Illnesses As Well As Potential Biomarkers For Clinical Applications. More Than An Update, This Publicatio
on of stress response, but is also involved in numerous cortical functions, such as cognition, memory, learning, mood and behavior. Additionally, the catecholaminergic
ed with completely different field of investigation, namely, with application of focused ultrasound for activation of peripheral receptor structures. Stimulation of variou
Outer Layers Including New Modalities For Choroid Imaging, Out-Layer Diseases Such As The Various Types Of Macular Degeneration, Retinal Diseases Such As D
ngs, and emerging perspectives in the application of nano-scale technologies, this book is a comprehensive reference source for synthetic chemists, engineers, graduate
s in cell therapy, tissue engineering, biosensing, and diagnosis.the interface of chemistry, materials science, and biology presents many opportunities for developing inn
of facultative adult hepatic progenitor cells, nephron progenitor cells, adult stem cell niches, cancer stem cells, pluripotency and cellular heterogeneity, and cellular me
gth in lymphoid malignancies; telomerase and telomere maintenance in the blight fungus ustilago maydis; roles of mirnas in cancers; and genetic programming for mu
n esteem not only for their research, but also for their ability to communicate their subject to popular audiences.
explores the components of signaling pathways and how they are "wired" into pathways and circuits that can process information. The book concludes with a unique c
life science and biotechnology due to numerous recently revealed biological properties of these compounds. these compounds are scientifically and practically promis
tellectual property issues are discussed-the transition from the research laboratory into clinical testing is included<I>An introduction to biotechnology</I> is a biotech
mic platforms strongly suits this book as it is a very relevant in-demand title on key industrial enzymes. academic fraternity, genetic engineers and biotechnologists wo
of basic and clinical immunology. the superbly drawn figures are now in full color, complemented by full color plates throughout the book. the text is further enhanced
evidence-based medicine and the subjectivity and narrative truth of the physician-patient relationship. The book offers a thoughtful tour of key topics in the standoff b
stablished the molecular structure of troponin. the advanced knowledge gained from basic research of troponin allows for a better understanding of the current method
oplatforms to gain control of their biological fate-significant procedures to synthesize advanced nanomedicines are analyzed. Proper formulation strategies, in case stud
d pathologic considerations, and provides comprehensive coverage of surgeries for the head and neck subsites. Also included are valuable chapters on surgery for chem
e, to identify. these realities ultimately challenge the conceptual framework of current cancer biology.this book introduces a new concept of genome theory of cancer e
ifen-discusses electrical properties of cancer cells as biochemical explanations alone does not answer many biological processes and electrical characteristics of cells n
linical epidemiology to molecular cancer therapeutics. the most relevant clinical aspects such as imaging, new surgical and radiation techniques, and the role of endoc
s been performed as well. In the final chapters, the properties of the new perspective hypercrosslinked polymeric hemosorbents are presented. The monograph could b
experience and knowledge of the authors. It contains many great illustrations, which help the reader to understand the new knowledge easily. It also includes authorita
iple myeloma along with the risk factors involved and the treatments that are available.
at includes both the family and the community and is provided in a range of settings, from the hospital, to the community health center, to home. this unique and timel
ven occur before the primary tumor is identified. Historically, these conditions were considered rare, but given the difficulties with diagnosis, the exact prevalence is u
s And, Importantly, The Development Of Resistance. <Br>This Book Provides An Up-To-Date Overview Of The Advances And Limitations Of Targeted Therapy For
operative and post-operative care of patients with neurological disorders this new edition will again be the go to reference for both neurologists and general practitione
amide drugs have been originally developed as potent antimicrobial agents, and several antiepileptic sulfonamides show efficacy in epilepsy. This book will describe a
ala, emotion and the sexually dimorphic social behavior network. (Imprint: Nova Biomedical)
epressive disorder; betaine in the brain; clinical outcome prediction using bayesian regression and artificial neural networks; pathological changes of event-related bra
scusses several different causes of hyperhidrosis, as well as treatment options and outcomes.
ns and other antiviral drugs, new antifungal medications, and vaccinations against Lyme disease and bacterial meningitis.
infiltration of inflammatory cells is accompanied by the release of a number of cytokines that target neurons, astrocytes and microglia. This interaction between the im
d general medical professionals; a first stop for a focused review of the state of the art for understanding the neurologic impact of each covered disease.
logists, neuroscientists, and general medical professionals: a first stop for a focused review of the state of the art for understanding the neurologic impact of each cove
a first stop for a comprehensive and focused review of the state of the art for understanding the neurologic impact of each covered disease.
ly seeks an account of how neurological knowledge acquired such an expansive view of human nature as to become concerned in the last decades of the twentieth cent
via networks how these networks interact in normal brain function major mechanisms that control network function the interaction of the normal networks to produce m
y, basic neurobiological sciences, clinical presentation and complexity, and major treatment options. the list of contributors include professors, researchers, phd studen
ons. More Than An Update, This Publication Indicates The Next Steps To Discover Biomarkers And Understand Psychiatric Disorders More Comprehensively.<Br>T
ehavior. Additionally, the catecholaminergic system appears to control vital hypothalamic functions. Several physiological processes, including growth, sexual regulat
al receptor structures. Stimulation of various neural structures was implemented with the use of short pulses (stimuli) of focused ultrasound in the MHz-frequency ran
r Degeneration, Retinal Diseases Such As Diabetic Retinopathy And Vascular Occlusion, And Retina And Vitreous Interface Pathologies. The Final Chapters Are Dedi
e for synthetic chemists, engineers, graduate students, and researchers with an interest in the multidisciplinary applications, as well as the ongoing research in the field.
sents many opportunities for developing innovative tools to diagnose and treat various diseases. however, cell surface engineering using chemistry and materials scien
y and cellular heterogeneity, and cellular mechanisms of somatic stem cell aging.
mation. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, fol
unds are scientifically and practically promising in medicine and agriculture due to their biosurfactant and fungicidal properties, as well as a number of other biologica
troduction to biotechnology</I> is a biotechnology textbook aimed at undergraduates. It covers the basics of cell biology, biochemistry and molecular biology, and intr
y, genetic engineers and biotechnologists would be greatly enriched with the current knowledge on key enzymes of industrial relevance.
ghout the book. the text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights.
oughtful tour of key topics in the standoff between EBM and CAM: how and why the double blinded, randomized clinical trial (RCT) came to be called the gold stan
d. Proper formulation strategies, in case studies from recent literature, are exhaustively described-potential use of multifunctional nanostructures for simultaneous sele
ed are valuable chapters on surgery for chemoradiation failures, reconstruction techniques for surgical defects, and oncologic and functional outcomes using open surg
a new concept of genome theory of cancer evolution, in an attempt to unify the field.
cesses and electrical characteristics of cells need to be harnessed for better treatment outcomes, especially to those who are unresponsive to conventional chemo therap
radiation techniques, and the role of endocrine therapy and chemotherapy in the systemic treatment of endometrial cancer will also be discussed.
bents are presented. The monograph could be interesting for a wide array of specialists in the fields of resuscitation, healthcare therapy, oncology and surgery, as well a
w knowledge easily. It also includes authoritative and expert opinions and advice regarding the treatment and management of the patients with medulloblastoma.
ealth center, to home. this unique and timely book captures the progress and vision of many dedicated groups throughout the middle east and the usa who have been w
ies with diagnosis, the exact prevalence is unknown. This book focuses on the symptoms, diagnosis, and treatment of PNS.
s And Limitations Of Targeted Therapy For Several Tumor Entities Including Breast Cancer, Colon Cancer, Gastrointestinal Stromal Tumors, Lung Cancer, Melanoma
s; pathological changes of event-related brain oscillations in parkinsons disease; the impact of sub thalamic stimulation on autonomic dysfunction in parkinsons disea
ction of new treatments targeting ms. this collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest mult
d microglia. This interaction between the immune system and the central nervous system modulates many cerebral functions, such as: neural remodeling, synaptic plas
pact of each covered disease.
tanding the neurologic impact of each covered disease.
covered disease.
ned in the last decades of the twentieth century with the human sciences, philosophy, art and literature.
raction of the normal networks to produce more complex behaviors how brain disorders can result from abnormal interactions how therapy of disorders can be advanc
include professors, researchers, phd students, clinical psychiatrists and psychologists; they belong to different universities and training institutions and all of them pos
ic Disorders More Comprehensively.<Br>This Publication Is Valuable Reading For Psychiatrists, Neuroscientists And Analytical Chemists Interested In The Basics O
processes, including growth, sexual regulation, and salt and water balance are regulated by catecholamines, either directly or via complex circuitries involving numero
cused ultrasound in the MHz-frequency range.
e Pathologies. The Final Chapters Are Dedicated To The Practicality Of Using Oct For The Pre- And Postsurgical Evaluation Of The Posterior Segment And For The D
neering using chemistry and materials science approaches is a new and diverse field.
iochemistry and molecular biology, and introduces laboratory techniques specific to the technologies addressed in the book; it addresses specific biotechnologies at bo
trial (RCT) came to be called the gold standard in modern medicine; the challenge of postmodern medicine that countered the positivism of evidence-based medicin
ctional nanostructures for simultaneous selective disease imaging and efficient image-guided drug delivery is discussed. Additional attention is given to the potential in
ic and functional outcomes using open surgery, chemoradiation, and transoral surgery.
unresponsive to conventional chemo therapies-discusses low and high voltage electroporation of primary, adult, human, mesenchymal cells using bleomycin chemo dr
are therapy, oncology and surgery, as well as for researchers aimed toward the development of new types of biocompatible materials.
he middle east and the usa who have been working to advocate for and develop palliative care services in the region.
l Stromal Tumors, Lung Cancer, Melanoma, Ovarian Cancer And Renal Cell Carcinoma.
e and clinical applications of the latest multiple sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology
ns, such as: neural remodeling, synaptic plasticity, neurotransmitter releasing, stress-associated response, cognitive and mental disease progression, and others.
ons how therapy of disorders can be advanced through this network approachthis book will benefit neuroscience researchers and graduate students with an interest in n
and training institutions and all of them possess a distinguished expertise in the specific fields of interest.
lytical Chemists Interested In The Basics Of Proteomics And Metabolomics, Psychiatric Definitions And The Most Advanced Hypotheses About The Pathobiology Of
on Of The Posterior Segment And For The Differential Diagnosis Of Vitreoretinal Diseases As Well As In The Management Of Patients With Retinal And Neuro-Opht
k; it addresses specific biotechnologies at both the theoretical and applications levels. Biotechnology is a field that encompasses both basic science and engineering. Th
ed the positivism of evidence-based medicine; the politics of modern CAM and the rise of the National Center for Complementary and Alternative Medicine; an in-dep
ditional attention is given to the potential introduction of theragnostic nanomedicines into the clinic to develop personalized pharmacotherapies-discusses the latest an
esenchymal cells using bleomycin chemo drug Includes nanosecond, low voltage pulse electroporation of breast cancer cells using Tamoxifen, the hormone drug comm
arch community and the clinical neurology community of researchers and practitioners.
rs and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders.
ced Hypotheses About The Pathobiology Of Schizophrenia, Depression And Bipolar Disorder.
asses both basic science and engineering. There are currently few, if any, biotechnology textbooks that adequately address both areas. Engineering books are equation-h
mentary and Alternative Medicine; an in-depth case study of homeopathy explaining why this modality has emerged as a poster-child for CAM; and finally an assessm
d pharmacotherapies-discusses the latest and most significant advances in the development of nanomedicines against cancer, inflammatory diseases, autoimmune dise
ls using Tamoxifen, the hormone drug commonly used<I>Electroporation-based therapies for cancer</I> looks at electroporation-based therapies for cancer. Cancer ki
both areas. Engineering books are equation-heavy and are written in a manner that is very difficult for the non-engineer to understand. Numerous other attempts to pres
ster-child for CAM; and finally an assessment of CAMs popularity despite its poor performance in clinical trials.
er, inflammatory diseases, autoimmune diseases, pain treatment, infectious diseases, blood and cardiovascular diseases, metabolic diseases, central nervous system dis
oration-based therapies for cancer. Cancer kills about one American per minute, amounting to over 500,000 deaths in the US and millions, worldwide, each year. There
nderstand. Numerous other attempts to present biotechnology are written in a flowery manner with little substance. The author holds one of the first PhDs granted in b
tabolic diseases, central nervous system diseases and gene therapy<I>Nanoparticle-based approaches to targeting drugs for severe diseases</I> is devoted to the analy
S and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring an
thor holds one of the first PhDs granted in both biosciences and bioengineering. He is more than an author enamoured with the wow-factor associated with biotechnolo
r severe diseases</I> is devoted to the analysis of the latest developments in the use of passive and/or active targeting nano-strategies for controlling the biodistribution
ities, especially for inoperable, recurring and chemo-resistant cancers, that do not respond well to current treatment regimen. Electrical-pulse-mediated, enhanced drug
h the wow-factor associated with biotechnology; he is a practicing researcher in gene therapy, cell/tissue engineering, and other areas and has been involved with emerg
-strategies for controlling the biodistribution profiles of pharmacotherapy agents. Special attention is given to recent advances in these engineering approaches: specifi
n. Electrical-pulse-mediated, enhanced drug delivery technique, known as electroporation is one of the ways to effectively treat these patients. Towards this end, this b
ther areas and has been involved with emerging technologies for over a decade. Having made the assertion that there is no acceptable text for teaching a course to intro
ces in these engineering approaches: specifically, to target nanomedicines against severe diseases, and to the development of multifunctional nanoplatforms for combin
treat these patients. Towards this end, this book provides a comprehensive overview of electroporation-based clinical studies in the hospitals for various cancer treatme
acceptable text for teaching a course to introduce biotechnology to both scientists and engineers, the author committed himself to resolving the issue by writing his ow
of multifunctional nanoplatforms for combined selective diagnosis and effective pharmacotherapy. Current pharmacotherapy against severe diseases frequently fails du
es in the hospitals for various cancer treatments including melanomas, head and neck cancers, chest wall breast carcinomas and colorectal cancers and research studies
y against severe diseases frequently fails due to the little or negligible specificity of drug molecules for non-healthy cells. Even more advanced pharmacotherapy agen
and colorectal cancers and research studies in the lab using cell lines, primary cells, and animals. This technique is especially suitable for low and middle-income cou
Even more advanced pharmacotherapy agents can exhibit a very low accumulation into the disease site, and an extensive biodistribution into healthy tissues. As a conse
ally suitable for low and middle-income countries, where due to lack of infrastructure and resources, many cancers are diagnosed at late stages and this safe, effective,
odistribution into healthy tissues. As a consequence, long-term pharmacotherapy is characterized by significant inefficacy and severe toxicity. In order to meet the chal
nosed at late stages and this safe, effective, economical, out-patient-based and quick (it only takes a few minutes to treat a tumor) technique is a boon to these patients
nd severe toxicity. In order to meet the challenge, the introduction of nanotechnology into pharmacology is under intense investigation. Nano-pharmacology, which pr
tumor) technique is a boon to these patients for palliative and other care with enhanced quality of life. From basics to clinical medical applications of electroporation a
nvestigation. Nano-pharmacology, which primarily involves the formulation of nanoparticulate carriers for drug molecules, is considered a revolutionary concept in the
cal medical applications of electroporation are discussed by interdisciplinary authors including practicing oncological surgeons, medical professional, and academic an
is considered a revolutionary concept in the disease arena. The use of biodegradable nanoplatforms loaded with pharmacotherapy agents can result in improved drug
therapy agents can result in improved drug localization into the disease site with negligible distribution into non-targeted sites. As a result, the therapeutic activity of s
tes. As a result, the therapeutic activity of such molecules will be significantly enhanced, and the systemic side effects will be minimized as well. However, recent in v
be minimized as well. However, recent in vivo investigations have shown the limitations of the use of conventional nanocarriers. Interestingly, novel nano-engineering
arriers. Interestingly, novel nano-engineering strategies have been introduced in the formulation of nanoparticulate platforms for the delivery of drugs to non-healthy tis
s for the delivery of drugs to non-healthy tissues. Such approaches are even capable of overcoming multi-drug resistances expressed by non-healthy cells. This book p
expressed by non-healthy cells. This book provides an in-depth and detailed analysis of the above problems, and a comprehensive discussion of the available solutions
hensive discussion of the available solutions. It focuses on aspects of the formulation of drug nanocarriers, alongside characterization techniques, toxicity issues, regula