Documenti di Didattica
Documenti di Professioni
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Biomaterials
l ffor
Orthopaedic Surgeons
Tariq Nayfeh, M.D./Ph.D.
Outline
Introduction
oduc o
Basic Definitions
Joint Mechanics
Mechanics of Materials
Bending Theory
Biomaterials
To Pass Exams?
This area is actually a low yield area for time spent
studying and the number of questions asked
Basic Definitions
Biomechanics
o ec a cs is
s the
e science
sc e ce of
o the
e
action of forces, internal or external
on the living body.
Statics is the study of forces on
bodies at rest
Dynamics is the study of the motion
of bodies and the forces that
produce the motion
Basic Definitions
Principle Quantities
Basic
as c Quantities
Qua
es
Length
Time
Mass
Derived Quantities
Velocity
Velocit (length/time)
Acceleration (length/time2)
Force (mass length/time2)
Sca a qua
Scalar
quantities
es have
a e magnitude
ag ude
but no direction.
Time, speed (not velocity), mass, volume
Vectors
Fy
Fx
Moments
A moment
o e (torque)
( o que) is
s the
e rotational
oa o a
effect of a force about a point.
F
=
d
M=Fxd
First Law:
An object at rest will remain at rest and
an object in motion will continue in
motion with a constant velocity unless it
experiences a net external force
Inertia is the tendency of an object to
either remain at rest or to maintain uniform
motion in a straight line
The weight of a body is a vector quantity
that is equal to the force of gravity acting
on it
By
y combining
co b
g the
e first
s and
a d second
seco d
laws: For equilibrium to occur the
sum of the forces and moments
must be equal to zero
F 0
Third Law:
For every action
there is an equal and
opposite reaction.
Joint Mechanics
How do joints
j
maintain stability?
What produces
joint movement?
Joint Mechanics
Joint Mechanics
Joint
o
reaction
eac o
forces occur at the
joint center
Joint Mechanics
When
e the
e muscle
usc e and
a d joint
jo
reaction
eac o
forces are balanced equilibrium
occurs and the body segments do
not accelerate
Illustrative Problem
F
W=20 N
G= 15 N
B R G W 0
R B 15 20
R B 35
M 0
B 3 G 15 W 30 0
20 30 15 15
B
275 N
3
R 240 N
Illustrative Problem
Hip
p Reaction
eac o forces
o ces in single
s g e leg
eg
stance
10
Illustrative Problem
This
s pe
person
so is
s trying
t y g to liftt a 20
0 kg
g
object.
Illustrative Problem
If the p
person bends
forward
Lw = 25 cm
Lp = 40 cm
Mspine = 450x0.25+200x0.4
Mspine =192.5 Nm
11
Hip
p jjoint contact forces
Single leg stance 2 to 3 x BW
Walking
- 3 x BW
Stairs, running
- 5 to 7 x BW
Mechanics of Materials
In o
order
de to
o understand
u de s a d how
o materials
a e as
behave we need to define some
basic quantities.
12
Stress
Stress is the intensity
y
of internal force.
A
Beer and Johnston, Mechanics of Materials
AO/ASIF
13
14
Strain
Strain (Engineering):
Relative measure of the
deformation (six
components) of a body as a
result of loading.
L
L
AO/ASIF
15
Shear strain
Usually
Usua
y expressed
e p essed as an
a angle
a g e radians
ad a s
16
Hoop stress
Hoop stress is the stress in a
direction perpendicular to the
axis of an item
***As the
thickness of the
item decreases
the hoop stress
increases***
Why is this
important?
pr
t
pr
2
2t
Hoop Stress
As humans age,
g , the
diameter of their
bones increase, but
the thickness
decreases
We will see later that this
change is not bad for ordinary
human activity. It matters
most when we as surgeons
intervene.
17
Material Testing
In o
order
de to
o characterize
c a ac e e how
o materials
a e as
behave we have to create standardize
methods to test them and document
the behavior.
Materials Testing
Materials of standardized sizes and shapes
p are
placed in testing machines and loaded
following standardized protocols
18
Stress-Strain Curves
Standardized curves used to help quantify
how a material will respond to a given load.
load
AO/ASIF
Yield Strength:
g
The stress level at which
a material begins to deform plastically
Ultimate Strength: The stress level at
which a material fails
Modulus of Elasticity: The linear slope
of the materials elastic stress-strain
behavior.
Ductility: The deformation to failure
Toughness: Energy to failure (the area
under the stress strain curve)
19
AO/ASIF
AO/ASIF
20
Types of failure
Ductile
B ittl
Brittle
21
22
Stiffness
Unloaded:
A=cross section area
E=Youngs modulus of elasticity
F
u
F = SEA
ax u = Saxu
L
Force-Displacement Curves
Similar to stress-strain
curves
Depends
p
on
Material
Geometry
23
Force-Displacement Curves
Question
The linear relationship between an applied stress and the resultant
deformation defines a material's
1- modulus of elasticity.
2- brittleness.
3- yield strength.
4- ultimate strength.
5- toughness.
24
Bending of Beams
Most
os bo
bones
es and
a d orthopaedic
o opaed c
implants are subjected to axial,
bending, and torsion loading
Most failures occur secondary to
bending and torsion
25
26
eccentric
load
eccentric
load
coompression tensioon
coompression tension
coompression tensioon
centric
load
Lo w s t re s s
High
stress
27
Bending Resistance
The
e resistance
es s a ce of
o a beam
bea to
o bending
be d g
is directly proportional to its
moment of inertia
28
The
e bending
be d g stiffness
s
ess of
o a half
a pin
p is
s
proportional to one half the radius of
the pin to what power?
2
3
4
One third
One fourth
Relative bending
resistance
Solid rod
Flat beam
3.5
I beam edge on
I beam flat
0.6
Hollow cylinder
5.3
Identical size
of
cross sectional
area
29
R1
R2
64
d14
d 24
64
4 4
54
64
64
4
4
R2 R1 5 4
625 256
1.44 100%
4
R1
256
4
850Kg. 800Kg.
60Kg.
Bone-implant composite
20Kg.
AO/ASIF
30
31
32
torque
shear
Mechanical Properties of
Materials
Isotropy
py
Material properties
do not depend on
direction
Steel
Aluminum
Anisotropy
py
Material properties
depend on the
direction of loading
Bone
Tendons
Ligaments
Cement
33
Anisotropy
Bone is an
anisotropic
material
Hence failure
depends on load
direction and
loading type
Bone Mechanics
Cortical bone is
weakest in directions
that cause tensile
stresses.
In the transverse
direction the bone is
acting as a brittle
material
34
a compression
p
crack begins
g
at the fulcrum.
bone is weaker in tension than in compression.
bone is weaker in compression than in tension.
the forces are equally resolved between tension and
compression.
5. the forces are resolved into pure tension.
Bending forces in the long bones most commonly result in what type of fracture
pattern?
1- Short oblique
2- Transverse with butterfly
3- Linear shear of 45
4- Spiral
5- Segmental
35
AO/ASIF
Bending forces in the long bones most commonly result in what type of fracture
pattern?
1- Short oblique
2- Transverse with butterfly
3- Linear shear of 45
4- Spiral
5- Segmental
36
A 27
27-year-old
year old patient sustains the
closed femoral fracture shown. This
fracture pattern is most likely the
result of which of the following
forces?
1.
Pure torsion
2.
Pure bending
3.
Pure compression
4.
Four-point bending
5.
37
Clinical Question
Case 1: A 75 year old female
with osteoporosis falls and
sustains a supracondylar
femur fracture. The patient
undergoes ORIF with a
locked supracondylar plate.
She is allowed to increase
her weight bearing to full
weight bearing at 6 weeks.
Two weeks later she
presents with increasing
pain, swelling and can not
bear weight.
Clinical Example
Case 2: A 75
5 year
yea old
o d female
e a e with
osteoporosis falls and sustains an
intertrochanteric hip fracture. She
undergoes ORIF with an
intramedulary device and is allowed
to weight bear as tolerated the next
day Her fracture goes on to heal
day.
without complications.
38
Clinical Example
Case 3: An 83 y
year old male
with multiple medical
problems presents with
severe right hip pain and
the inability to bear
weight. He had undergone
a revision of his right total
hip 10 years
ea s ago to a
cementless stem.
Clinical Case
Why
y did
d d the
e patient
pa e in Case 2 do well
e
while the patients in Case 1 and
Case 3 have their implants fail?
39
Fatigue
Fatigue
g
testing
g is done using
g the same type
yp
of samples and machines that are used to
create stress-strain curves. However, the
samples are loaded cyclically to failure.
The goal of testing is to determine how
many loading cycles at a given load a
material can withstand before failing.
g
**The failure stress levels are not the
same as the yield stress and ultimate
stress.**
Fatigue
Fatigue
g
testing
gg
generated fatigue
g
life curves.
40
Fatigue Life
Endurance
Limit
Fatigue Life
41
Bone Fatigue
Bone
o e has
as no
o in vitro
o endurance
e du a ce
limit!
In vivo bone heals
If bone fails to heal when subjected
to cyclic loads we get stress
fractures
Clinical Examples
In Case 1 above
abo e the
e patient
pa e was
as
allowed to weight bear before her
fracture healed. In this case the
stress from walking on the bone
resulted in rapid failure with
relatively few cycles.
42
Case 3
The
e applied
app ed stress
s ess
to the small
diameter implant
again resulted in
fatigue failure of
the stem
Stress Concentration
When a structural member contains a
discontinuity such as a hole or a sudden
discontinuity,
change in cross section, high localized
stresses may occur near the discontinuity.
43
Stress Concentration
The highest
g
stress
concentration occurs
near a sharp point
y max n 1 2
1.
2.
bone is anisotropic.
3
3.
bone is viscoelastic.
viscoelastic
4.
5.
44
Viscoelasticity
Viscoelasticty
y is a term used to describe
materials that demonstrate time-dependant
behavior to loading.
Visco is derived from viscocity (fluid like)
Elastic come from elasticity (solid like)
Viscoelasticity
As
simple
p e model
ode for
o an
a elastic
e as c
material is a simple spring in which
instantaneous displacement occurs
to an applied load.
The energy
ene g of
displacement is stored as
potential energy and
recovered when the load
is removed.
Buckwalter, et al. Orthopaedic Basic Science
45
Viscoelasticity
Viscous
scous be
behavior
a o can
ca be modeled
ode ed as
a dashpot (shock absorber).
Deflection occurs in response to the
rate of force application
IIn this
thi case th
the
energy produced
from loading is
dissipated as heat.
Buckwalter, et al. Orthopaedic Basic Science
Viscoelasticity
Viscoelastic
scoe as c Behavior
e a o is
s modeled
ode ed as
a combination of elastic and viscous
materials.
46
The biomechanical p
properties
p
of ligaments
g
and bone demonstate
1.
a time-dependent behavior.
2.
a rate-independent behavior.
3.
4.
modeling
g with linear elastic-spring
p g
elements.
5.
47
Stress Relaxation
48
Stress Shielding
Wolffs
Wolff
s law
If you dont use it, you lose it!
Stress
Shielding
P
E
p
Ess
Eb
E
190
10 b
p p b
17
Eb
F A
P Fp Fb
P Ap p Ab b (10 Ap Ab ) b
P
(10 Ap Ab )
p 10
P
(10 Ap Ab )
49
Stress shielding
2.
Polyethylene debris-induced
osteolysis
3.
Senile osteoporosis
4.
5.
Diffuse osteopenia
50
Stainless Steel
51
Cobalt-Chromium Alloys
Titanium
52
Ceramics
Polymers
Polymers
y
are large
g molecules made from
combinations of smaller molecules
Nylon, PMMA, Polyethylene
53
Polymers
Polyethylene
Semi-crystalline
y
polymer
p y
54
2.
3
3.
4.
5.
Crosslinking
C oss
Crosslinking
g is
s done
do e to
o create
c ea e larger
a ge
molecular polyethylene molecules
that can theoretically be more wear
resistant
There are two common methods for
crosslinking
g
Irradiation
Free radical generating chemical
55
Crosslinking
56
Crosslinking
Tribology
The study of Friction, Lubrication,
and Wear.
57
Friction
is
LOAD
FRICTION FORCE
DIRECTION OF
MOTION
58
Lubrication.
materials
applied
to the interface
reducing friction and
wear.
Lubrication.
Lubrication
reduces Wear
reduces Friction
59
Lubrication modes
Boundary
Lubrication
Hydrodynamic
Lubrication
Hydrostatic Lubrication
STRIBECK CURVE
Coefficient
of Friction
()
BL
ML
FFL
Sommerfeld Number
(viscosity x sliding speed x radius / load)
60
Boundary Lubrication
Boundary Lubrication
No
o pressure
p essu e build
bu d up in the
e
lubricant.
Loading is 100% carried by the
asperities in the contact area.
The contact area is protected by
absorbed molecules of the lubricant
and / or a thin oxide layer.
The characteristics for boundary
lubrication is the absence of
Hydrodynamic pressure.
61
No Friction or Wear
Hydrodynamic Lubrication
Bearings
ea gs are
a e supported
suppo ed by a thin
layer of fluid which is pulled into the
bearing through viscous
entrainment, compressed, creating a
sufficient hydrodynamic pressure to
support load.
h
HD h >0.25m
EHD h ~0.025m
- 2.5 m
62
Hydrodynamic Lubrication
Pressure builds as
speed increases.
The surface
asperities are
completely separated
by a lubricant film.
63
Hydrostatic Lubrication
Bearings
ea gs
are
a e supported
suppo ed on
o a thick
c
film of fluid supplied from an
external pressure source.
64
2.
3.
4.
5.
Clearance
65
Radius Cup
R2
-- Radius
Head R1
-= Radial
Clearance
-Clearance
allows a fluid
Is there an optimal
clearance?
No
N
one clearance,
l
it
i
is a ratio to head
diameter
The bigger the head
gets, the bigger the
clearance gets
We must consider
manufacturing
capabilities Nominal
and Ranges etc
The lubricant fluid in
Vivo
V
ti ht
66
tight
and too high
clearances
may end up
in high wear
rates
t due
d to
t
an increase in
friction
Radiolucencies
observed in superior
acetabulum in 10% of
the cases to date.
Reduced
Clearance
bearings need further
assessment.
67
Regular BHR
80
Urin
ne Output g/24hr
70
60
50
40
30
20
10
0
Pre Op
5 day
2 month
6 month
1 year
4 year
68