Natural products and plant disease resistance

RA Dixon - Nature, 2001 - nature.com.sci-hub.org

... limiting enzyme is conceptually a simple strategy, but in most cases the flux control points in the
pathway are not understood. Transferred DNA (T-DNA) activation tagging has recently been
applied to the characterization of transcriptional regulators of natural product pathways ...
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dari nih.gov
Opportunities for enzyme engineering in natural product biosynthesis
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P Bernhardt, SE O'connor - Current opinion in chemical biology, 2009 - Elsevier

Organisms from all kingdoms of life produce a plethora of natural products that display a
range of biological activities. One key limitation of developing these natural products into
pharmaceuticals is the inability to perform effective, fast, and inexpensive structureactivity ...
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dari vtt.fi
Pharmacological properties of the ubiquitous natural product betulin
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S Alakurtti, T Mkel, S Koskimies - European journal of , 2006 - Elsevier

... Please enable JavaScript to use all the features on this page. European Journal of Pharmaceutical
Sciences. Volume 29, Issue 1, September 2006, Pages 113. Cover image Cover image. Review.
Pharmacological properties of the ubiquitous natural product betulin. ...
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An enzyme-release assay for natural cytotoxicity

C Korzeniewski, DM Callewaert - Journal of immunological methods, 1983 - Elsevier
For the best product experience, we recommend you upgrade to a newer version of IE or use
a different browser: Firefox or Chrome. For additional information please see the ScienceDirect
Blog page. ... An enzyme-release assay for natural cytotoxicity . ...
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A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and
incorporation in natural product biosynthesis
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W Zhang, ML Bolla, D Kahne - Journal of the American , 2010 - ACS Publications

A number of natural products contain a 2-amino-3-hydroxycyclopent-2-enone five
membered ring, termed C5N, which is condensed via an amide linkage to a variety of
polyketide-derived polyenoic acid scaffolds. Bacterial genome mining indicates three ...
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Racemisation in asymmetric synthesis. Dynamic kinetic resolution and related processes

inenzyme and metal catalysis
FF Huerta, ABE Minidis, JE Bckvall - Chemical Society Reviews, 2001 - pubs.rsc.org.sci-hub.org
... of the bromide source and the lipase employed led to an optimised system where an immobilised
phosphonium bromide was used together with cross-linked enzyme crystals from Candida ... These
can serve as useful precursors for drug or natural product synthesis (Scheme 20). ...
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Natural products in drug discovery and development

GM Cragg, DJ Newman, KM Snader - Journal of natural products, 1997 - ACS Publications
... product; ND ) derived from a natural product; S ) synthetic; S* ) synthetic modeled on a natural
product parent. ... cardiotonic, cerebral vasodilator, chelator, choloretic, chrysotherapeutic, cognition
enhancer, coronary vasodilator, cystic fibrosis, diuretic, enzyme, gastropro- kinetic ...
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Designed divergent evolution of enzyme function
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Y Yoshikuni, TE Ferrin, JD Keasling - Nature, 2006 - nature.com.sci-hub.org

... REVIEWS. Mining and engineering natural-product biosynthetic pathways Nature Chemical
Biology Perspective (01 Jul 2007). See all 4 matches for Reviews. ... RESEARCH. Biosynthesis
of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme ...
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dari ibin.gov.in

The influence of natural products upon drug discovery

DJ Newman, GM Cragg, KM Snader - Natural product reports, 2000 - pubs.rsc.org.sci-hub.org
... In the nomenclature of Cragg et al., 84 these would be classified as S* compounds;
synthetic in nature but derived from a natural product prototype. 5.3 Cardiovascular:
angiotensin converting enzyme inhibitors (ACE inhibitors). ...
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The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol
by the cytochrome P450 enzyme CYP1B1
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GA Potter, LH Patterson, E Wanogho, PJ Perry - British journal of , 2002 - nature.com.sci-hub.org

... Resveratrol is a natural product found in red wine, and has been shown to have cancer
preventative properties (Jang et al, 1997; Jang and Pezzuto, 1999). ... The enzyme CYP1B1 belongs
to the cytochrome P450 enzyme family (Spink et al, 1994; Sutter et al, 1994). ...
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