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Several Hormones are Involved in Control of Salt, Water and Osmotic Pressure
Blood pressure, activity of nerves and muscles and other functions depend upon
close regulation of body ______ & _________.
ADH (antidiuretic hormone) _______ ___________ by causing water pores to be
inserted in the collecting duct of the kidney
Aldosterone __________ ____ ____________ by the kidney (distal tubule)
Secretion of these hormones is controlled by ______________ _______:
o if the blood osmotic pressure is too high ADH secretion is increased
o if the blood volume falls aldosterone will increase
o a number of hormones are involved in the control of Ca
Growth of the ovaries and testes and secretion of sex hormones is controlled by
FSH and LH
At birth oxytocin causes contraction of uterine muscles, aiding in delivery
Milk production involves many hormones, including prolactin
Milk ejection (letdown) when the baby suckles is also caused by oxytocin
The immediate response to stress is the ______ or ______ reaction, which has
both nervous and hormonal components
The hormonal component is the release of large amounts of __________ (and
some norepinephrine) by the adrenal medulla; this hormone stimulates the heart,
lungs and other organs involved in the emergency response
Long term stress will cause release of large amounts of ________ from the
adrenal cortex (essential for life); blood glucose is raised
Deleterious effects of prolonged stress are increased blood pressure and inhibition
of the immune system
Survey of the Major Endocrine Organs & Their Hormones & Functions
(Considerably Simplified)
Gland
Posterior
Pituitary
Thyroid
Parathyroid
Hormones
Target Organ
Functions
Adrenal Cortex
Thyroid
FSH & LH
Ovaries
Testes
Secretion of Hormones
Growth of Sex Glands
Reproductive Functions
Prolactin
Mammary Gland
Milk Production
Growth Hormone
Most Tissues
ADH
Kidney
Water Retention
Oxytocin
Mammary Gland
Uterus
Milk Ejection
Childbirth
Thyroxine, T3
Most Tissues
Calcitonin
Bone
PTH
(Parathormone)
Bone
Kidney
Kidney
Many Tissues
Many Tissues
Many Organs
Pancreas
Skin, Liver
&Kidney
Kidney
Insulin
Muscle, Fat,
Liver
Glucagon
Liver
Raises Blood Ca
Bone Marrow
Cytokines:
o Small proteins
o Act on same cell that produces them (autocrine) or on nearby cells
(paracrine);
o rarely they enter the blood and are transported to distant parts of the body
o Mainly involved in defense of the body (many are produced by white
blood cells)
Examples:
o Nerve growth factor
o Tumor necrosis factor
o Vascular endothelial growth factor (VEGF): involved in angiogenesis
(production of new capillaries
o Interleukins
o Prolactin & growth hormone: act as both hormones and cytokines