Drug Name

Generic name:
Rosuvastatin
calcium
Brand Name:
TORUS
Dosage:
20mg OD
Date Medication
Prescribed:
September 11,2014

Classification

Mechanism of
Action

Indication

Contraindication

Side Effects

Nursing
Interventions

Antihyperlipidemic
drug
HMG-CoA
reductase inhibitor

>a fungal metabolite

that inhibits the
enzyme(HMG-CoA)
that catalyzes the first
step in cholesterol
synthesis pathway,
resulting in a decrease
in serum cholesterol,
serum LDLs and
either increase or no
change in serum
HDLs.

>as an adjunct to
diet in the
treatment of
elevated total
cholesterol and
LDL cholesterol
and triglyceride
levels in patients
with primary
hypercholesterole
mia.

>contraindicated with
allergy to any
component of the
product, active liver dse.
or persistent elevated
serum transaminase,
pregnancy, lactation
>use cautiously with
impaired hepatic
function, alcoholism,
renal impairment,
advanced age,
hypothyroidism

>CNS: headache,
dizziness,
insomnia,
hypertonia,
paresthesia,
depression,
anxiety, vertigo,
neuralgia

>establish baseline
serum lipid levels
and liver function
test results before
beginning therapy

>adjunct to diet
to slow
atherosclerosis
progression in
patients with
elevated
cholesterol
>as an adjunct to
diet for the
treatment of
patients with
elevated serum
triglyceride levels
>to reduce LDL-

>CV:
hypertension,
angina pectoris,
vasodilation,
palpitation,
peripheral edema

>consult dietician
about low
cholesterol diets
>administer drugs
at bedtime(highest
rate of cholesterol
synthesis occur
between midnight
and 5am)

>GI: nausea,
dyspepsia,
>monitor patients
diarrhea,
for closely for signs
constipation,
of injury
gastroenteritis,
vomiting,
flatulence,
peridontal
abscess, gastritis,
liver failure
>RESPIRATORY

C, total
cholesterol, and
ApoB in patients
with homozygous
familiar
hypercholesterole
mia as an adjunct
to other lipidlowering
treatments or if
such treatments
are available.

: pharyngitis,
rhinitis, sinusitis,
cough, dyspnea,
pneumonia
Other: arthritis,
arthralgia,
rhabdomyolysis,
myopathy, flulike
symptoms