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International Journal of Recent Advances in Pharmaceutical Research

April 2013; 3(2): 1-20


____________________________________________________________________________________________________________________________________________

Natures Aphrodisiacs - A Review of Current Scientific Literature


(1)ALOK

SEMWAL*, (2) RATENDRA KUMAR , (1) RAMANDEEP SINGH

(1)- Himachal
(2)- Meerut

Institute of Pharmacy, Paonta Sahib-173025, H.P (India)


Institute of Engineering & Technology, Meerut-250005, UP (India)

Abstract
Despite progress made in modern medical science herbal drugs constitute a major share of all the officially recognized
systems of health in India viz. Ayurveda, Yoga, Unani, Siddha, Homeopathy and Naturopathy. More than 70% of Indias 1.1
billion populations still use these non-allopathic systems of medicine. Various synthetic drugs like Sildenafil citrate,
Tadalafil citrate, Vardenafil, etc are used to treat ED but these drugs also have fatal side effects. The use of synthetic
aphrodisiacs results in the dilation of blood vessels in other parts of the body causing headache and fainting. Other side
effects include facial flushing, stomach upset, blurred vision and sensitivity to light which usually occur at higher doses.
Thus, there is growing need to look for aphrodisiacs more of herbal origin as opposed to synthetic compounds which are
known to cause severe unwanted side effects. Unlike the old-time aphrodisiacs, which were meant only to increase sex
drive and/or sexual pleasure, modern stimulants including Viagra, may rightly be called medications, since their purpose
is to correct problems that make sex difficult or impossible. Besides of the fact that several plant sources contain
aphrodisiac ingredients (phytochemicals) which can be beneficial as an immune modulator, sex stimulant and also as
medication in erectile dysfunctions, there is very low range of research work carried out in this field. This review contains
a collection of more than 200 medicinally important plants which are not only aphrodisiac in nature but also used to treat
ED. All the herbal plants in this review are verified from the Current Scientific Literature as well as traditional book.

Keywords: Erection, Erectile dysfunction (ED), Aphrodite, Sexual stimulants, Herbal.

1.0. INTRODUCTION
Male sexual problems include libido, erection,
ejaculation and orgasm. Male sexual response cycle
is called normal if all the steps are timely and
sequentially if any one of the following is not in
sequence or delayed than it leads sexual
dysfunction in humans. Male sexual dysfunction
(MSD) could be caused by various factors. These
include: psychological disorders (performance
anxiety, strained relationship, depression, stress,
guilt and fear of sexual failure), androgen
deficiencies (testosterone deficiency, hyperprolactinemia), chronic medical conditions (diabetes,
hypertension,
vascular
insufficiency
(atherosclerosis, venous leakage), penile disease
(Peyronies, priapism, phinosis, smooth muscle
dysfunction), pelvic surgery (to correct arterial or
inflow
disorder),
neurological
disorders
(Parkinsons disease, stroke, cerebral trauma
Alzhemiers spinal cord or nerve injury), drugs (side

_________________________________________________
*Correspondence

Alok Semwal
Assistant Professor
Himachal Institute of Pharmacy,
Paonta Sahib, H.P
E-mail Id: alokm.pharm01@gmail.com

effects) (anti-hypertensives, central agents,,


psychiatric medications, antiulcer, antidepressants,
and anti-androgens), life style (chronic alcohol
abuse, cigarette smoking), aging (decrease in
hormonal level with age) and systemic diseases
(cardiac, hepatic, renal pulmonary, cancer,
metabolic, post-organ transplant) [1-3]. One of the
measure sexual problems arising in the modern
time is due to erectile dysfunction which is also
associated with depression, endocrine, neurologic,
vascular, and systemic disorder [4]. Erectile
dysfunction is a broad category that includes
inability to achieve erection, or the ability to achieve
only brief erections [5]. Besides of ED there are
various sexual dysfunctions like Disorders of
ejaculations, disorders of orgasm, and failure of
detumescence. .
By the several years clinical and
epidemiological studies it has been proved that
several risk factors are associated with ED. These
risk factors include smoking, age, obesity, and
diabetes and also various stress conditions. An
important point to notice here is that these risk
factors are the same as the risk factors of
cardiovascular disease. So even ED is not a life
threatening disease, it may represent as an early

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

sign of cardiovascular disease [6]. Synthetic drugs


like Sildenafil citrate, Tadalafil citrate, Vardenafil,
Tadalafil, Alprostadil, Papaverin are used to treat
ED but these drugs also have fatal side effects like
sudden hypotension, hypersensitivity reaction,
abnormal vision, infertility, suicidal tendencies,
mental disorders and tremors [7]. The use of
synthetic aphrodisiacs results in the dilation of
blood vessels in other parts of the body causing
headache and fainting. Other side effects include
facial flushing, stomach upset, blurred vision and
sensitivity to light which usually occur at higher
doses. The world health organization survey
suggests that a very big portion of the world
populations rely on medicines that are obtained
from plant sources in their primary healthcare. The
increase in such popularity of herbal medicines also
brought the attention towards the safer use of such
herbal medicines which are used frequently such as
aphrodisiacs.
2.0. APHRODISIACS
Sexual stimulants are still often called
"aphrodisiacs" (after Aphrodite, the Greek goddess
of love). Aphrodisiacs are the agents which are used
extensively by the human beings seeking to improve
their sexual life and help in erectile dysfunctions
(ED) sometimes called impotence.
Ayurveda has a whole science of
Aphrodisiacs. It is one of the seven branches of its
medical
system.
Ayurvedic
Aphrodisiacs
(Vajikarana in Sanskrit) are more than substances
exiting sexual activity; they are tonics that nurture
and give direct sustenance to the reproductive
tissues. Others help promote the creative
transformation of sexual energy for the benefit of
the body-mind. Sexual desire is controlled and
regulated by the central nervous system which
integrates tactile, olfactory, specific auditory and
mental stimuli. The aphrodisiac drugs act by

altering the level of specific neurotransmitters or


specific sex hormones into the body [8]. Most of the
aphrodisiacs agent acts by altering the testosterone
and progesterone concentration in the body.
2.1 Mechanism
potentials

involved

in

Aphrodisiac

On sexual stimulation (visual (or) otherwise the


famines of the axons of parasympathetic nerves
release nitric oxide (NO) gas. The gas diffuses into
smooth muscle cells that line those arteries of the
corpus carvenosum (spongy erectile tissue) and
activates the enzyme guanylate cyclase (GC). The
later
converts
the
nucleotide
guanosine
triphosphate (GTP) into cyclic guanosine
monophosphate (cGMP). The cGMP in turn causes
the smooth muscle cells around the penis to relax,
leading to dilation and increased flux of blood into
the penile tissue. This blood is essentially trapped in
the penis and results in an erection. The erection
ceases after a while because cGMP is hydrolyzed by
phosphodiesterase type-5 enzyme (PDE-5) into
inactive GMP. (The PDE-5 enzyme resides in the
penile tissues). Aphrodisiac potentials inhibit the
hydrolyzing action of PDE-5 with the result that
active cGMP can accumulate. Undisturbed and
prolong the erection through increased blood flow
[9]. Possible mode of action of aphrodisiac potential
of medicinal plants is given in Figure 1.
3.0.
PLANTS
POTENTIALS

CONTAINING

APHRODISIAC

According to recent scientific literature several


medicinal plants have been identified or evaluated
for their aphrodisiac potential. Some of the plants
are given in Table 1. Besides of the fact that these
plants are aphrodisiacs in nature and claimed to
have good aphrodisiac potential their actual action
is not yet proved by scientific methods.

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

Aphrodisiac bioactive principles


Peripheral activity
Central

Steroidal saponins
Central acting

Intermediate in
steroidal pathway
of androgen
production

Binds to enzymes
involved in
androgen
production

Increases levels of
LH and FSH

Alkaloids

Flavonoid
s

Increase the
release of NO from
endothelia and
nerve endings of
male rats

Elevates testicular
cholesterol content
of male rat

Steroidogenesis
Dehydroepiandrosterone
biosynthesis

Relaxes corpus
arvernosum smooth
muscle in the male
rat copulatory organ

Steroid

Increase in
dehydroepiandrosterone

Dilates blood
vessels in
sexual organs
of male rats

Acts centrally as
Gamma amino
butyric acid (GABA)
antagonist

Increase in
testosterone

Enhanced sexual behavior in


male rats
Enhanced sexual
pleasure

Enhanced
sexual desire

Enhanced sexual
motivation

Enhanced sexual
performance

Increased % index of
libido
Increased MF
Reduced ML
Increased % Mounted

Increased IF
Reduced IL
Increased % intermitted

Prolonged EF
Prolonged EL
Reduced PEI
Increased % ejaculated
Increased % copulatory efficiency
Decreased % intercopulatory interval

Figure 1: Possible mode of action of aphrodisiac bioactive principles in male rats [10]

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

Table 1: Medicinal plants having aphrodisiac potential


Sr. No.

Name of Plant

Common name

Family

Part used

Reference

Bhindi

Malvaceae

Root

[11]

2.

Abelmoschus esculantus
(L.)
Abelmoschus moschatus

Musk mallow

Malvaceae

Seed

[12-13]

3.

Abrus preacatorium Linn. Ganja

Fabaceae

Seed

[14]

4.

Abrus precatorius L.

Crab's Eye

Paplionaceae

Seed

[15-16]

Abutilon indicum (Linn.)

Thuthi

Malvaceae

Seed, root,
bark, leaf

[12]

6.

Acacia catechu Willd.

Catechu

Mimosaceae

Heartwood

[12,18]

7.

Acacia nilotica L. Willd.

Gum Arabic tree

Fabaceae

Bark

[19]

8.

Achyranthes aspera Linn.

Apamarg, Latjeera

Amaranthaceae

Root

[11]

9.

Attesh

Ranunculaceae

Root

[11]

10.

Aconitum heterophyllum
Wall.
Acorus calamus Linn.

Sweet flag

Araceae

Rhizome

[20-21]

11.

Actiniopteris radiata Sw.

Morshikha

[22]

12.

Adenanthera pavonina

Baragunchi

13.

Alchornia floribunda Mull. Niando

Actinopteridacea Whole plant


e
Mimosaceae
Bark, seeds,
leaves
Euphorbiaceae
Root

14.

Allium sativum L.

Garlic

Liliaceae

Bulb

[12,14,28]

15.

Allium tuberosum

Chiense chive

Zingiberaceae

Seed

[25-26]

16.

Aloe excels Berger

Zimbabwe Aloe

Asphodelaceae

Leaf

[29]

17.

Aloe vera

Liliaceae

leaves

[133]

18.

Alpinia galanga Willd.

Kumari
Ghritakumari
Java galangal

Zingiberaceae

Rhizome

[30]

19.

Amaranthus spinosus L.

Chaulai

Amaranthaceae

[11]

20.

Anacyclus pyrethrum

Akarakarabha

Compositae

Leaves, Whole
plant
Root

21.

Arachis hypogaea Linn.

Peanut

Fabaceae

Seeds

[23]

22.

Argyreia nervosa

Adhoguda

Convolvulaceae

Root

[34]

1.

5.

[23]
[24]

[31]

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

Jack tree

Moraceae

Asparagus

25.

Artocarpus heterophyllus
Linn.
Asparagus racemosus
Willd.
Asphaltum bitumen

[23]

Liliaceae

Fruit, Seed,
Leaves, root
Root

Shilajit

Pitch

[129]

26.

Azadirachita indica

Neem

Meliaceae

Root

[11 ]

27.

Bacopa monnieri L.

Brahmi

Scrophulariaceae Whole plant

[11]

28.

Bauhinia tomentosa Linn. Manja Mandaram

Caesalpiniaceae

Seed

[12]

29.

Bauhinia vahlii

Caesalpiniaceae

Seed

[12]

30.

Bauhinia variegate Linn.

Camels Foot
climber
Bauhinia

Caesalpiniaceae

Bark

[12]

31.

Benincasa hispida Cogn.

Ash gourd

Cucurbitaceae

Fruit

[12]

32.

Blepharis edulis Linn.

Utangan/ Shikhi

Acanthaceae

Seeds

[35]

33.

Blepharis sindica

Acanthaceae

Seeds

[127]

34.

Boerhavia diffusa L.

Untkantalo/Bhangari
Punarnava

Nyctaginaceae

Root

[11]

35.

Boesenbergia rotunda L.

Temu kunci

Zingeberaceae

Rhizomes

[25,36]

36.

Bombax ceiba Linn.

Silk-Cotton Tree

Bombacaceae

Bark

[12]

37.

Bussea occidentalis

Kpayeli

Caesalpiniaceae

Bark, seed

[37]

38.

Butea frondosa Roxb.

Flame-of-the-forest Papilionaceae

Whole plant

[12, 25]

39.

Butea superb Roxb

Red kwao kruva

Fabaceae

palm pollen

[135]

40.

Cajanus cajan (L.) Millsp.

Arhar

Fabaceae

Root

[11]

41.

Cannabis indica L.

Indian hemp

Cannabinaceae

Leaf

[38]

42.

Cannabis sativa

Bhang

Cannabinaceae

Leaf

[11 ]

43.

Pitipiti

Capparidaceae

Root

[39]

44.

Capparis erythrocarpus
Isert.
Capsicum annuum L.

Capsicum

Solanaceae

Seed

[40]

45.

Carica papaya L.

Papita

Caricaceae

Fruit

[11]

46.

Carpolobia alba G. Don

Polygalaceae

Stem bark, Twig

[134].

47.

Cassia occidentalis Linn.

Osunsun, Guineabissau
Kasondhi

Fabaceae

Leaf

[41]

48.

Cassia sieberiana DC

African laburnum

Caesalpiniaceae

Leaf

[37]

23.
24.

[32-33]

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

Chenopodium album

Amaranthaceae

lamb's quarters, [128]


melde, goosefoot

49.
50.

lamb's quarters,
melde, goosefoot
and fat-hen

Chenopodium album L.

White goosefoot

Chenopodiaceae

Seed

[42-44]

51.

Chione venosa (Sw,) Urb.

Fatpork

Rubiaceae

Bark and roots

[136]

52.

Chlorophytum borivilium

Liliaceae

Roots

[105]

53.

Chlorophytum tuberosum
Baker.
Cissus quadrangularis

Safed Musli, white


musli
Safed musli

Liliaceae

Whole plant

[45]

Veldt
Grape or Devil's
Backbone
Edible stemmed
vine
colocynth, bitter
apple, bitter
cucumber,
watermelondesert

Vitaceae

Edible stemmed
vine

[106]

Vitaceae

Root

[12]

Cucurbilaceae

Fruit & seed

[107]

Cucurbitaceae

Seed

[108]

Agnimantha, Jaya,
Verbenaceae
Sriparni,
Ganikarika,
Jayanthi, Tarkari,
Nadeyi, Vai jayanthi

Root

[109]

[46]

54.
Cissus quadrangularis
Linn.
Citrullus colocythis

55.
56.
57.

Citrullus lanatus
Clerodendrum phlomoidis

58.
59.

Cocculs cardifolia Linn.

Guduchi

Menispermaceae

60.

Cocos nucifera Linn.

Coconut

Arecaceae

Stem, leaf,
Root
Endosperm

61.

Cola acuminate Schott.

Cola

Malvaceae

Seed

[48]

62.

Cola caricaefolia G.Don

Bumoguan Leaf

Sterculiaceae

Leaf

[37]

63.

Cola gabonensis Schott &


Endl.
Cola nitida Schott & Endl.

Kola nut

Sterculiaceae

Fruit

[24]

Kola nut

Sterculiaceae

Seed

[24]

Cola pachycarpa Schott &


Endl.
Cola rostrata Schott &
Endl.

Kola nut

Sterculiaceae

Seed

[24]

Kola nut

Sterculiaceae

Seed

[24]

Commiphora wightii

Guggal, Guggul or M Burseraceae


ukul myrrh tree

Stem

[110]

Commiphora caudata Wt.


& Arn.
Commiphora mukul Hook.
ex Stocks

Emporium of
medicinal plants
Indian bdellium
tree

Burseraceae

Root, leaf

[12]

Burseraceae

Root, leaf

[12]

64.
65.
66.
67.
68.
69.

[14,47]

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

70.

Convolvulus microphyllus

Shankhpushpi

Convolvulaceae

Leaves

[111]

71.

Corchorus depressus

Cham Ghans

Tiliaceae

Whole plant

[112]

72.

Coriandrum sativum Linn. Coriander

Apiaceae

Leaf

[42]

73.

Ivory coast

Rubiaceae

Stem, Bark

[39]

74.

Corynanthe pachycerus K
Schum.
Crocus sativus Linn.

Saffaron

Iridaceae

Stigma

[25]

75.

Crotalaria burhia

Saniya

Crotalaria burhia

Whole plant

[113]

Cucumis callosus

Melon, Muskmelon,
Cantaloupe,
Honeydew, Sugar
melon
Pumpkin

Cucurbitaceae

Fruit

[114]

Cucurbetaceae

Seed

[137]

76.
77.

Cucurbita pepo L.

78.

Curculigo orchioides
Gaertn.

Musali

Hypoxidaceae/
Amaryllidaceae

Rhizome

[137-141]

79.

Curcuma amada Roxb.

Mango ginger

Zingiberaceae

Rhizome

[12-13]

80.

Poaceae

Whole plant

[12]

Orchidaceae

Root

[20,49]

82.

Cymbopogon citrates (DC.) Lemongrass


Stapf
Dactylorhiza
Marsh Orchis
hatagirea (D. Don) Soo.
Dalbergia sissoo Roxb.
Shisham

Fabaceae

Wood

[41-42]

83.

Daucus carota L.

Carrot

Umbelliferae

Root

[50]

84.

Desmodium gangeticum
Linn.

Desmodium

Fabaceae
(Papilionaceae)

Root

[12]

85.

Dioscorea bulbifera Linn.

Wild Yam

Dioscoreaceae

Whole plant

[41]

86.

Diospyros melanoxylon
Roxb.
Dolichos lablab Linn.

East Indian ebony

Ebenaceae

Flower

[12, 41]

Flat bean, sem

Fabaceae

Seeds

[23]

Putjev

Euphorbiaceae

Leaf juice

[41]

89.

Drypetes roxburghii
(Wall.)
Durio Zibenthinus Murr.

Durian Fruit

Bombacaceae

Fresh fruit

[25,51]

90.

Echinacea purpurea L.

Compositae

Leaves

[52]

91.

Indian head, comb


flower
Isongoroit

Ekerbegia capensis
Sparrm.
Emblica officinalis Gaertn. Emblic

Meliaceae

Root

[29]

Euphorbiaceae

Fruit

[53-54]

Eriodendron
Anfractuosum DC.

Bombaceae

Whole plant

[46]

81.

87.
88.

92.
93.

White silk cotton


tree

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

94.

Erthroxylem catuaba

Catuaba

Erthroxylaceae

Bark

[130]

95.

Euadenia eminens Hook.f.

Dinsinkro

Capparidaceae

Root

[39]

Euphorbia hirta L

Asthma weed, Cats Euphorbiaceae


hair, Egele, Nonan
kurchiya, Odane
inenmili

Whole plant

[134].

97.

Euphorbia hirta L.

Dudhi

Euphorbiaceae

Leaves

[37]

98.

Eurycoma longifolia Jack

Tongkat Ali

Simarubaceae

Whole plant

[55-63]

99.

Evolvulus alsinoides L.

Shankhahuli

Convolvulacae

Whole plant

[23]

100.

Rubiaceae

Stem

[64-65]

101.

Fadogia agrestis Schweinf. Black aphrodisiac


Ex Heim
Ferula hermonis
Shilsh-el-zallouh

Umbelliferae

Root

[66]

102.

Ficus arnottiana Miq.

Paras Pipal

Moraceae

Bark

[67]

103.

Ficus racemosa L.

Gular

Moraceae

Fruit

[11]

104.

Ficus religiosa Linn.

Peepal tree

Moraceae

Bark

[12]

105.

Ficus retusa

Chilkan

Moraceae

Latex

[68]

106.

Ficus sycomorus (mig)

Baure

Moraceae

Root

[144]

107.

White-berry bush

Euphorbiaceae

Whole Plant

[48]

108.

Flueggea virosa Roxb. ex


Willd.
Garcinia afzelii Engl

Bitter kola

Guttiferae

Bark

[37]

109

Garcinia kola Heckel

Bitter kola

Guttiferae

Bark

[37]

110.

Ginko biloba

Ginkgo

Ginkgoaceae

Leaves, Seeds

[131]

111.

Glycyrrhiza glabra Linn.

Liquorice

Papilionaceae

Root

[137]

112.

Gmelina arborea Roxb.

Coomb teak

Verbenaceae

Fruit

[12]

113.

Gossypium arboretum
Linn.

Kapas

Malvaceae

[23]

114.

Grewia asiatica L.

Phalsa

Tiliaceae

Bark, seeds,
Leaves, root
Fruit

Tiliaceae

Fruit

[115]

Simaroubaceae

Bark

[37]

96.

Grewia tenax
115.
116.

White Crossberry,
Phalsa Cherry,
Raisin bush
Harissonia abyssinica Oliv Zigua

[42]

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

117.

Hibiscus rosa-sinesis

China rose

Malvaceae

Leaf

[12]

118.

Hibiscus sabdariffa Linn.

Roselle

Malvaceae

Seed, leaf

[12]

119.

Asclepiadaceae

Root

[12]

120.

Holostemma ada-kodien
Holostemma
Schult.
Hygrophila schulli (Ham.) Marsh Barbel

Acanthaceae

Root, leaf, seed

[12]

121.

Inalia catappa L.

Combretaceae

122.

Indigofera linnaei

India
almond,Umbrella
Vasuka

Fabaceae

[142]
Stem bark,
Kernel (Seeds)
Leaves and seed [116]

123.

Ipomoea digitata

Vidari kandha

Convolvulaceae

Root

[132]

124.

Ipomoea mauritiana Jacq. Giant potato

Convolvulaceae

Root

[12]

125.

Kaempferia parviflora

Krachaidum

Zingiberaceae

Rhizomes

[69]

126.

Khaya Senegale
nsis (Hochst)
Lagenaria vulgaris Ser.

African mahogany, Mimosaceae


dry zone mahogany
Bottle gourd
Cucurbitaceae

Root

[145]

Fruit

[12]

Hama-fufu

Apocynaceae

Root, Bark

[39]

129.

Landolphia dulcis
(Sabine) Pichon
Lepidium meyenii Walp.

Maca

Brassicaceae

Root

[70-71]

130.

Linum usitatissimum L.

Alsi

Linaceae

Seed

[11]

131.

Lycium barbarum

Solanaceae

Fruit

[117]

132.

Mangifera indica L.

Chinese wolfberry,
Chinese boxthorn,
Mango

Anacardiaceae

Bark

[12]

133.

Arrowroot

Zingiberaceae

Rhizome

[12]

134.

Maranta arundinacea
Linn.
Massularia acuminata

Chewing stick

Rubiaceae

Stem

[72]

135

Massularia acuminata

Bioko and Annobon Rubiacea

Stem bark, Root

[134].

136.

Vingar

Celastraceae

[134].

Senegal

Caesalpiniaceae

Leaves, Stem,
Root
Twig or Stem

139.

Maytenus senegalensis
(Lam.) Exell
Mezoneuron
benthamianum Baill
Microdesmis keayana J.
Leonard
Mimosa hamata

140.

Mimosa pudica L.

Mundi, Bander-kiFabaceae
Rakhi, Gulabi babul
Thottasiniki
Mimosoideae

141.

Mirabilis jalapa L.

Four o clock plant

142.

Momordica charantia
Descourt

Bitter Melon

127.
128.

137.
138.

Pandaceae

Stem
bark, leaves and
Seeds

[37]
[144, 145]
[118]

Aerial part

[73]

Nyctaginaceae

Root

[54]

Cucurbitaceae

Leaf

[74]

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____________________________________________________________________________________________________________________________________________

143.

Mondia whitei Linn.

144.

White's ginger

Periplocaceae

Root

[75]

Montanoa tomentosa Cerv. Zoapatle

Asteraceae

Whole plant

[76]

145.

Morinda lucida

Brimstonetree

Rubiacaeae

Leaves

[77]

146.

Moringa oleifera

Moringa

Moringaceae

Leaves

[119]

147.

Mucuna pruriens Linn.

Leguminosae

Seed

Fabaceae

Seed

[120],
[121]
[41]

Musaceae

[134]

Myristicaceae

Leaves, Roots,
Fruits
Seed

[41]

148.

velvet bean or
cowitch
Mucuna pruriens Linn. DC. Poonai kali

149.

Musa paradisiaca L.

150.

Myristica fragrans Houtt.

Plantain Ogede,
Ayaba,
Nutmeg

151.

Nerium indicum Mill.

Kaner/Kanail

Apocynaceae

Roots

152.

Nyctanthes arbartristis

Oleaceae

Flower and seed [122]

153.

Ocimum gratissimum

Night-flowering
Jasmine
Vana Tulsi

Labiatae

Leaves

[12]

154.

Orchis latifolia
Linn.
Oxyantllus unilocularis
Hiern
Pagenum harmala

Munjaataka

Orchidaceae

Roots

[78]

Ghana akan

Rubiaceae

Fruit, leaf

[37]

Nitrariaceae

Seed

[123]

157.

Esfand, wild rue,


Syrian rue
Palisota hirusta K. Schum. Ghana

Commelinaceae

Leaf

[79]

158

Panax ginseng

Ginseng

Araliaceae

Root

[80]

159.

Papaver somniferum L.

Poppy plant

Papaveraceae

Flower

[12]

160.

Passiflora incarnate L.

Wild Passion
Flower
Dorawa

Passifloraceae

Leaf

[81]

Fabaceae

Bark

[145]

Pierre
Yohimbin
Burra Gokhru

Rubiaceae

Bark

[82]

163.

Pausinystalia yohimbe
(K.Schum.)
Pedalium murex

Pedaliaceae

Whole plant

[84]

164.

Pfaffia paniculata

Suma

Papilionaceae

Root

[83]

165.

Phyllanthus amarus

Bahupatra

Euphorbiacea

Leaves

166.

Phoenix dactylifera

Date palm

Arecaceae

Pollen

[124],
[125]
[143]

167.

Piper betle Linn.

Vettrilai

Piperaceae

Leaf

[73]

168.

Piper guineense
Schumach.

West African
Pepper

Piperaceae

Root

[39]

155.
156.

161.

Parkia biglobos a

162.

[12, 25]

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____________________________________________________________________________________________________________________________________________

169.

Piper officinarum DC

170.

Piperaceae

Fruit

[12]

Annonaceae

Fruit, root, leaf

[85]

Liliaceae

Root

[20]

172.

Polyalthia suaveolens
Engl. & Diels
Polygonatum multiflorum Solomon's Seal
(L.) All
Prunus amygdalus batsch Badama

Rosaceae

Kernel

[23]

173.

Psoralea corylifolia Linn.

Bavaci

Fabaceae

Fruit

[23]

174.

Punica granatum L.

Anar

Punicaceae

Fruit

[11]

175.

Rauwolfia vomitoria Afzel Afzel. poison


devil's pepper

Apocynaceae

Root

[86-87]

Ballu

Ericaceae

Leaf, flower

[20]

Snow Rose

Ericaceae

Leaf, flower

[20]

178.

Rhododendron
anthopogon
Rhododendron lepidotum
Wall. ex D. Don
Ricinus communis L.

Castor

Euphorbiaceae

Seed

[12]

179.

Rosa damascene Mill

Rose

Rosaceae

Petal

[88]

180.

Ruta chalepensis L.

Garden rue

Rutaceae

Leaves

[144]

181.

Saccharum spontaneum
Linn.
Santalum album Linn.

Kasa

Poaceae

Root stock

[14,28]

Sandal wood

Santalaceae

Heart wood

[88]

Haritaki

Lamiaceae

Aerial parts

[136]

Gajapipali

Arecaceae

Fruit

[14, 28]

Violet tree

Polygalaceae

Root bark

[25]

186.

Satureja khuzestanica
Jamzad
Scindapsus officinalis
Schtt.
Securidaca
longepedunculata Slash
Sesamum indicum Linn.

Tilli / Til

Pedaliaceae

Seds

[41]

187.

Shorea robusta geartn

Sal, Kabba

[23]

188.

Sida acuta Burn.F.

Bala

Dipterocarpaceae Bark, leaves,


fruit
Malvaceae
Whole plant

189.

Sida cordifolia Linn.

Countary-mallow

Malvaceae

Root, seed

[12]

190.

Sida rhombifolia

Bagauli

Malvaceae

Root

[11]

191.

Solanum indicum Linn.

Indian night Shade

Solanaceae

Root

[12]

192.

Solanum melongena Linn. Brinjal

Solanaceae

Unripe fruit

[12]

193.

Solanum nigrum
Linn.

Solanaceae

Berries

[12]

171.

176.
177.

182.
183.
184.
185.

Chavica
officinarum
Polyalthia

Aguaragua

[11]

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____________________________________________________________________________________________________________________________________________

Botobotonisan

Asteraceae

Whole plant

[12]

Mundi

Asteraceae

Seeds

[11]

Atkapali

Bignoniaceae

[137, 143]

Strychnine tree

Loganiaceae

Root, bark,
flower
Seed

Clove

Myrtaceae

Iboga

Apocynaceae

Tabernanthe

Apocynaceae

Dried flower
bud
Root, bark,
stem
Root

[90-91]

200.

Sphaeranthus africanus
Linn.
Sphaeranthus indicus
Linn.
Stereospermumsuaveolens
DC.
Strychnos nux-vomica
Linn.
Syzygium aromaticum (L.)
Merrill & Perry
Tabernanthe iboga (L.)
Nutt.
Tabernanthe manii Baill.

201.

Tamarindus indica L.

Tamarind

Fabaceae

Bark

[93]

202.

Tamarix aphylla (L.) Karst Athel tamarisk

Tamariaceae

Bark

[42]

203.

Taxus baccata Linn.

Birmi

Taxaceae

Leaf

[12,14]

204.

Terminalia arjuna Roxb.

Arjuna

Combretaceae

Bark

[12]

205.

Terminalia catappa L.

Combretaceae
Menispermaceae

207.

Tinospora cordifolia
(Willd) Miers Hk.
Tribulus terrestris L. fruit

Stem bark,
Kernel (Seeds)
Whole plant

[134

206.

India almond,
Umbrella tree
Tinospora
Puncturevine

Zygophyllaceae

Fruit, seed

[94-97]

208.

Trichopus zeylanicus

Senna

Trichopodaceae

Leaves

[98]

209.

Trichosanthes dioica L
Roxb. Wild
Turnera
Aphrodisiaca
Turrea heterophylla Sm.
Sm.

Methi

Fabaceae

Seed

[12]

Damiana

Trneraceae

Areal part

[99]

Ahunanyakwa

Meliaceae

Root, bark,
Seed

[39]

Tynanthus panurensis
(Bur.)
Vitex negundo

Clavo huasca

Bignoniaceae

Bark, wood

[100-101]

Five-leaved chaste
tree
Valeriana jatamansi Wall. Jatamansi

Verbenaceae

Fruit

[126]

Valerianaceae

Root

[104]

215.

Vanda tessellata (Roxb.)


Hook. ex Don.

Rasna

Orchidaceae

Flower, Root

[102-103]

216.

Waltheria Indica

Hankufa

Sterculiaceae

The whole fruit

[145]

217.

Withania somnifera Linn.

Ashwagandha

Solanaceae

Leaf, Root

[12,41,42]

218.

Wrightia tinctoria (Roxb.) Ivory tree


R.Br.

Apocynaceae

Seed, Leaf, bark

[12]

194.
195.
196.
197.
198.
199.

210.
211.
212.
213.
214.

[89]

[24, 92]
[24,92]

[12-13]

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____________________________________________________________________________________________________________________________________________

219.

Ziziphusabyssin ica

Magarya

Rhamnaceae

Leaves

[145]

220.

Zingiber officinale Roscoe

Gingembre

Zingeberaceae

Rhizome

[48]

4.0 CONCLUSION
Sexual function is an important component of
quality of life and subject for well being in humans.
In modern time several factors like obesity, anxiety,
stress conditions, various disease conditions and
excessive use of medicines of synthetic origin has
increased the risk of sexual problems. Sexual
problems are related to sexual desire and male
erectile dysfunction. Successful treatment of sexual
dysfunction may improve not only sexual
relationships, but also the overall quality of life.
Thus, this review has dealt with screening of

medicinal plants from current scientific literature.


Since there are a number of traditional medicines
available with varied claims regarding their
therapeutic activity, it is necessary that research be
undertaken based on modern scientific methods
possibly leading to more panaceas in traditional
medicine. Scientists from divergent fields are
investigating new plants with an eye to their
aphrodisiac usefulness. These plants should be
subjected to animal and human studies to
determine their effectiveness and to develop herbal
formulations to treat sexual dysfunction.

REFERENCES
[1]. Guay AT, Spark RF, Bansal S, Cunningham GR,
Goodman NF, Nankin HR, Petak SM, and Perez
JB. American Association of Clinical
Endocrinologist: Medical Guidelines for
Clinical Practice for the evaluation and
treatment of male sexual dysfunction. A
couples problem. Endocrinol. Pract. 2003;
9(1):78-95.

[5]. Santosh BT, Chitme HR, Rabbani G, Jafar M.


Leptadenia Reticulata on stress modulated
sexual behavior of male rats. Research journal
of pharmacy 2011; 2(10): 27-36.

[2]. Feldman HA, Goldstein I, Hatzichristou DG,


Krane RJ, and McKinlay JB. Impotence and its
medical and psychosocial correlates: results of
the Massachusetts Male Aging Study. J. Urol.
1994;151:5461.

[7]. Kasper DL, Fauci AS, Longa DL, Braunwald E,


Hauser SL, Jameson JL. Harrisons Principles of
Internal Medicine 2005;16.

[3]. Kandeel FR, Koussa VKT, and Swerdloff RS.


Male sexual function and its disorders:
Physiology,
Pathophysiology,
Clinical
Investigation and, Treatment. Endocr. Rev.
2001;22(3): 342-388.
[4]. Malviya N, Jain S, Gupta VB, Vyas S. Indigenous
herbal remedies used by tribals of Madhya
Pradesh
for improving
their
sexual
performance and problem associated with
sexuality International Journal of Research in
Ayurveda and Pharmacy 2011;2(2):399-402.

[6]. Cirino G, Fusco F, Imbimbo C, Mirone V.


Pharmacology of erectile dysfunction in man.
Pharmacology and Therapeutics 2006;111:
400-423.

[8]. Patel DK, Kumar R, Prasad SK, Hemlata S.


Pharmacologically screened aphrodisiac plantA review of current scientific literature. Asian
pacific journal of tropical biomedicines
2011;131-138.
[9]. Chew KK, Stuckey BGA, Thompson PL. Erectile
dysfunction, sildenafil and cardiovascular risk.
Med. J. Aust, 172, 2000, 270-283.
[10]. Yakubu MT, Akanji MA. Effect of aqueous
extract of Massularia acuminate steam on
sexual behavior of male wister rats. Evidence
based complementary and alternative
medicine 2011.

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

13

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

[11]. Khan A, Khan A. Folk medicines for male


sexual disorders. Indian J. Traditional
Knowledge 2005;4 (3): 317-324.
[12]. Joy PP, Thomas J, Mathew S, Skaria PB.
Medicinal
Plants,
Kerala
Agricultural
University, Aromatic and Medicinal Plants
Research Station 1998.
[13]. Thomas J, Joy PP, Mathew S, Skaria BP, Duethi
PP, Joseph TS. Agronomic Practices for
Aromatic and Medicinal Plants Kerala
Agricultural University and Directorate of
Arecanut & Spices Development (Min. of Agri.,
Govt. of India), Calicut, Kerala, India, 2000.
[14]. Meena KA, Bansal P, Kumar S. Plants-herbal
wealth as a potential source of ayurvedic
drugs. Asian Journal of Traditional Medicines
2009; 4(4): 152-170.
[15]. Meena Misra. Editorial, The key to medicinal
plants research revolves around the detection,
isolation, and characterisation of antioxidants
as therapeutic agents, Journal of Medicinal
Plants Research 2009; 3(10):1.
[16]. Jahan S, Rasool S, Khan MA, Ahmad M, Zafar M,
Abbasi AM. Antifertility effects of ethanolic
seed extract of Abrus precatorius L. on sperm
production and DNA integrity in adult male
mice. J. Med. Plants Res. 2009; 3(10):809-814.
[17]. Husain A, Virmani OP, Popli SP, Misra LN,
Gupta MM, Srivastava GN, et al. Dictionary of
Indian Medicinal Plants, CIMAP, Lucknow,
India 1992: 546.
[18]. New TR, A biology of acacias, Oxford
University Press, Melbourne 1984: 193.
[19]. Kala PC. Indigenous uses, population density
and conservation of threatened medicinal
plants inprotected areas of the Indian
Himalayas, Conservation Biology 2005;19(2):
368-378.
[20]. Kapoor LD. CRC Handbook of Med. Ayurvedic
Plants, CRC Press 1990:18.
[21]. Willaman JJ, Li HL. Alkaloid bearing plants and
their contained alkaloids. J. Nat. Prod. Suppl.
1970;33 (3A).

[22]. Sikarwar RLS, Pathak B, Jaiswal A. Some


unique ethnomedicinal perceptions of tribal
communities of Chitrakoot, Madhya Pradesh.
Indian Journal of Traditional Knowledge 2008;
7(4): 613-617.
[23]. Agrawal SS. Clinically useful herbal drugs,
Ahuja Publications, Delhi; 2005:100-123.
[24]. Cousins D, Huffman MA. Medicinal properties
in the diet of gorillas: an ethnopharmacological evaluation. African Study
Monographs 2002; 23(2): 65-89.
[25]. Sumalatha K, Kumar SA, Lakshmi SM. Review
on Natural Aphrodisiac potentials to treat
Sexual dysfunction. International Journal of
Pharmacy & Therapeutics 2010;1: 10-18.
[26]. Kojima A, Nagato Y, Hinata K. Degree of
Apomixis in Chinese Chive (Allium tuberosum)
estimated by Esterase isozyme analysis. Japan
J. Breed 1991;4:73-83.
[27]. Choudhary R. Benificial effect of Allium
sativum
and
Allium
tuberosum
on
experimental
Hyperlipidemia
and
Atherosclerosis. Pak. J. Physiol. 2008; 4(2) 7-9.
[28]. Chopra R.N, Nayar SL, Chopra IC. Glossary of
Indian medicinal plants, NISCIR, CSIR, Delhi:
2002.
[29]. Gundidza GM, Mmbengwa VM, Magwa ML,
Ramalivhana NJ, Mukwevho NT, Ndaradzi W,
Samie A. Aphrodisiac properties of some
Zimbabwean medicinal plants formulations.
African Journal of Biotechnology 2009;
8(22):6402-6407.
[30]. Anand RM, Nandakumar N, Karunakarn L,
Ragunathan M, Murugan V. A Survey of
medicinal plants in Kollimalai hill tracts, Tamil
Nadu. Natural Products Radiance 2006; 5(2):
139-143.
[31]. Sharma Vikas, Thakur Mayank, Chauhan NS,
and Dixit VK. Evaluation of the Anabolic,
Aphrodisiac and Reproductive Activity of
Anacyclus Pyrethrum DC in Male rats. scientia
pharmaceutica 2009; 77:97-110.

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

14

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

[32]. Satyavati GV, Raina MK, Sharma M. Medicinal


Plants of India, Ind. Council on Med. Res. 1976,
New Delhi, Vol. 1.

[42]. Jaiswal S, Singh SV, Singh B, Singh HN. Plants


used for tissue healing of animals. Natural
Products Radiance 2004; 3(4): 284-292.

[33]. Dange PS, Kanitkar UK, Pendse GS. Amylase


and lipase activiities in the roots of A.
racemosus. Planta Medica, 1969;17: 393.

[43]. Burkill HM. The useful plants of West Tropical


Africa, Families AD. Royal Botanic Gardens,
Kew, United Kingdom 1985; 2(1):1960.

[34]. Subramoniam A, Madhavachandran V, Ravu K,


and Anuja VS. Aphrodisiac property of
elephant creeper Argyreia nervosa. Journal of
Endocrinology
&
Reproduction
2007;
11(2):82-85

[44]. Vanwyk BE, Gericke . Peoples plants: a guide


to useful plants of southern Africa, Briza
Publications, Pretoria, South Africa 2000: 351.

[35]. Pandey M, Pathak A. Investigation of


Aphrodisiac potentials of Blepharis edulis
Linn. Claimed by tribals of malwa region of
Madhya Pradesh. International Journal of
Pharma Tech. Research 2009;1(3):769-776.
[36]. Ching LYA, Wah ST, Sukari AM, Lian CEG,
Rahmani M, Khalid K. Characterization of
flavonoid derivatives from Boesenbergia
rotunda (L.). The Malaysian Journal of
Analytical Sciences 2007; 11(1): 154-159.
[37]. Sugiyama Y, Koman J. The Flora of Bossou: its
utilization by Chimpanzees and Humans.
African Study Monographs 1992;13(3): 127 169.
[38]. Grierson Abraham G. The hemp plant in
Sanskrit and Hindi literature. The Indian
Antiquary 1894; 23: 260-262.
[39]. Agbovie T, Amponsah K, Crentsil OR, Dennis F,
Odamtten GT, Djan WO. Conservation and
Sustainable Use of Medicinal Plants in Ghana.
Ethnobotanical Survey 2002.
[40]. Elferink RGJ. Aphrodisiac Use in PreColumbian Aztec and Inca Cultures. Journal of
the History of Sexuality 2000; 9(1/2): 25-36.
[41]. Singh K.P, Kumar V, Tiwari KR, Sharma A, Rao
CV, Singh R.H. Medico-Ethnobotany of
Chatara Block of District Sonebhadra, Uttar
Pradesh, India. Advances in Biological
Research 2010; 4(1): 65-80.

[45]. Maiti S, Geetha KA. Horticulture Floriculture


(Ornamental, Medicinal & Aromatic Crops).
Medicinal and Aromatic Plants in India 2007.
[46]. Prasanth PR, Kumar A. Ethno-medico botany
of medicinal plants for the treatment of
diabetic activity in Krishna district, Andhra
Pradesh. International Journal of Pharma
Research and Development 2008; 9: 1-9.
[47]. Dahanukar SA, Thatte UM. Therapeutic
approaches in Ayurveda Revisited, Poppular
Prakashan, Mumbai 1989; 109-10.
[48]. Mugisha MK, Origa HO. Traditional herbal
remedies used in the management of sexual
impotence and erectile dysfunction in western
Uganda. African Health Sciences 2005;5(1):
40-49.
[49]. Thakur M, Dixit VK. Aphrodisiac Activity of
Dactylorhiza hatagirea (D.Don) Soo in Male
Albino Rats. Evid Based Complement Alternat.
Med. 2007; 4(1): 29-31.
[50]. Woys WW. Heirloom Vegetable Gardening,
New York, Henry Holt and Company 1997.
[51]. Weenen H, Koolhaas EW, Apriyantono A.
Sulfur- Containing Volatiles of Durian Fruits
(Durio zibethinus Murr.). J. Agric. Food Chem.
1996;44(10):3291-3293.
[52]. Laughlin MG. Medicinal Plant review. Aust. J.
Med. Herbalism 4 (4): 1992.
[53]. Cynthia W. Love Potions - a guide to
aphrodisiacs. Optima Books 1993.

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

15

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

[54]. Ahmad SS. Medicinal wild plants from LahoreIslamabad motorway (m-2). Pak. J. Bot.
2007;39(2): 355-375.
[55]. Ang HH, Lee KL, Kiyoshi M. Sexual arousal in
sexually sluggish old male rats after oral
administration of Eurycoma longifolia Jack. J.
Basic Clin. Physiol. Pharmacol. 2004;15(3-4)
:303-309.
[56]. Ang HH, Ngai TH, Tan TH. Effects of Eurycoma
longifolia Jack on sexual qualities in middle
aged male rats. Phytomedicine 2003;10(6-7):
590-593.
[57]. Ang HH, Cheang HS. Effects of Eurycoma
longifolia jack on laevator ani muscle in both
uncastrated
and
testosterone-stimulated
castrated intact male rats. Arch. Pharm. Res.
2001; 24(5):437-440.
[58]. Ang HH, Ngai TH. Aphrodisiac evaluation in
noncopulator male rats after chronic
administration of Eurycoma longifolia Jack.
Fundam. Clin. Pharmacol. 2001;15(4): 265268.
[59]. Ang HH, Ikeda S, Gan EK. Evaluation of the
potency activity of aphrodisiac in Eurycoma
longifolia Jack. Phytother. Res. 2001;15(5):
435- 436.
[60]. Ang HH, Cheang HS, Yusof AP. Effects of
Eurycoma longifolia Jack (Tongkat Ali) on the
initiation
of
sexual
performance
of
inexperienced castrated male rats. Exp. Anim.
2000; 49(1):35-38.
[61]. Ang HH, Sim MK. Eurycoma longifolia
increases sexual motivation in sexually naive
male Rats. Arch. Pharm. Res. 1998; 21(6):
779-781.
[62]. Ang HH, Sim MK. Eurycoma longifolia Jack and
orientation activities in sexually experienced
male rats. Biol. Pharm. Bull. 1998;21(2):153155.
[63]. Ang HH, Chan KL, Gan EK, Yuen KH.
Enhancement of Sexual Motivation in Sexually
Naive Male Mice by Eurycoma longifolia.
Pharmaceutical Biology 1997;35(2):144-146.

[64]. Yakubu MT, Adewmi MA, Oladiji TA.


Alterations in serum lipid profile of male rats
by oral administration of Aqeous extracts of
Fadogia agrestis. Research Journal of
Medicinal Plants 2008; 2(2): 66-73.
[65]. Yakubu MT, Akanji MA, Oladiji AT. Aphrodisiac
potentials of the aqueous exract of Fadogia
agrestis (Schweinf. Ex Heirn) stem in male
albino rats. Asian Journal of Andrology
2005;7(4): 399- 404.
[66]. Hadidi KA, Aburajai T, Battah, AK. A
Comparative study of Ferula hermonis root
extract and sildenafil on copulatory behavior
of male rats. Fitoterapia 2003;74: 242-246.
[67]. Bakshi DNG, Sharma PS, Pal DC. A Lexicon of
Indian Medicinal Plants. Naya prakashan, New
Delhi 2001; (2):190.
[68]. Swapnadeep Parial, Jain DC, Joshi, SB.
Antidiabetic activity of Ficus retusa leaves.
Drug Invention today 2010;2(1):96-101.
[69]. Chaturapanich G, Chaiyakul S, Verawatnapakul
V, Pholpramool. Effect of Kaempferia
parviflora extract on reproductive parameters
and spermatic blood flow in male rats.
Reproduction research. 2008; 136: 515-522.
[70]. Gonzales GF, Gasco M, Cordova A, Chung A,
Rubio J, Villegas L. Effect of Lepidium meyenii
(Maca) on spermatogenesis in male rats
acutely exposed to high altitude (4340 m).
Journal of Endocrinology 2004;180: 8795.
[71]. Gonzales GF, Cordova A, Vega K, Chung A,
Villena A, Gonez C. Effect of Lepidium meyenii
(Maca), a root with aphrodisiac and fertilityenhancing properties, on serum reproductive
hormone levels in adult healthy men. Journal
of Endocrinology. 2003;176: 163-168.
[72]. Yakabu MT, Adewumi MA, Akanji AT, Oladiji.
Androgenic potentials of aq. extract of
Massularia acuminate (G.Don) Bullock ex
Hoyl.stem in male wistar rats. Journal of
ethanopharmacology 2008; 118 :508-513.
[73]. Sankaranarayanan S, Bama P, Ramachandran J,
Kalaichelvan
TP,
Deccaraman
M,

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

16

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

Vijayalakshimi M. et al. Ethnobotanical study


of medicinal plants used by traditional users in
Villupuram district of Tamil Nadu,India.
Journal of Medicinal Plants Research
2010;4(12): 1089-1101.
[74]. Sharma
VN.
Some
observations
on
hypoglycaemic
activity
of
Momordica
charantia. Indian J. Med. Res. 1960;48(4):47147.

[82]. Fabricant SD, Farnsworth RN. The Value of


Plants Used in Traditional Medicine for Drug
Discovery. Environmental Health Perspectives
2001;109(1): 69-75.
[83]. Arletti R, Benelli A, Cavazzuti E, Scarpetta G,
Bertolini A. Stimulating property of Turnera
diffusa and Pfaffia paniculata extracts on the
sexual-behavior
of
male
rats.
Psychopharmacology (Berl).1999;143(1):1519.

[75]. Watcho P, Fotsing D, Zelefack F, Nguelefack TB,


Kamtchouing P, Tsamo E et al Effects of
Mondia whitei extracts on the contractile
responses of isolated Rat vas deferens to the
potassium chloride and adrenaline. Indian J.
Pharmacol. 2006; 38(1):33-37.

[84]. Balamurugan G, Muralidharan P, Polapala S.


Aphrodisiac activity and curative effect of
Pedalium murex (L.) against ethanol-induced
infertility in male rats. Turk J. Biololgy 2010;
34:153-163.

[76]. Zepeda RER, Gloria LE, Lopez GM, Villarreal


LM, Chvez RE, Torres MJ. Montanoa
tomentosa glandular trichomes containing
kaurenoic acids chemical profile and
distribution. Fitoterapia 2009;80: 12-17.

[85]. Bouquet A, Cave A, Paris R. Plantes


medicinales du Congo-Brazzaville (III)
Medicinal Properties in the Diet of Gorillas 75
plantes medicinales et phytotherapie. Tome
1971;2: 154-158.

[77]. Yinusa Raji, Olumide S, Akinsomisoye Toyin M,


Salman. Antispermatogenic activity of Morinda
lucida extract in male rats. Asian J. Androl
2005;7(4): 405-410.

[86]. Ogunlesi M, Okiei W, Ofor E, Awonuga O.


Determination of the Concentrations of Zinc
and Vitamin C in Oysters and Some Medicinal
Plants used to Correct Male Factor Infertility.
Journal of Natural Products 2009;2: 89-97.

[78]. Thakur M, Dixit VK. Ameliorative Effect of


Fructo-Oligosaccharide Rich Extract of Orchis
latifolia Linn. On Sexual Dysfunction in
Hyperglycemic Male Rats. Sex Disabil. 2008;
26: 3746.
[79]. Benson BB, Berko AY, Berko MAJ, Coulibaly
KW, Ehile EE. Assessment of Sexual Stimulant
Potential of Total Flavonoids Extracted from
Leaves of Palisota Hirsuta Thunb. K. Schum
(Commelinaceae). European Journal of
Scientific Research 2008; 22(4):533-538.
[80]. Izzo, Angelo A, Mariana amato. Review-The
Aphrodisiac and adaptogenic properties of
ginseng. Fitoterapia 2000; 71: S1-S5.
[81]. Gilman FE. Passiflora incarnata-Wild Passion
Flower, Series of the Environmental
Horticulture Department, Florida Cooperative
Extension Service, Institute of Food and
Agricultural Sciences, University of Florida.
Fact Sheet FPS-457, 1999:1-3.

[87]. Principe P. The economic significance of plants


and their constituents as drugs In: Wagner H,
Hikino H, Famsworth NR, (Eds.), Economic and
Medicinal Research. Academic Press, London
1989;3:1-17.
[88]. Garg
SC. Essential oils as Therapeutics.
Natural Product Radiance 2005; 4(1):18-26.
[89]. Meena KA, Yadav KA, Panda P, Preet K, Rao
MM. Review on Stereospermum suaveolens DC
A Potential Herb. Drug Invention Today 2010;
2(5): 238-239.
[90]. Khan M.A. Akseer-e-Azam. Kanpur, India.
Matba Nizami 1886;(3): 563.
[91]. Baytar I, Cairo. Egypt. Matba Zahiyah Zaaherah
Mutawaffarah 1869:7-9.

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

17

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

[92]. Dubois L, Tabernanthe iboga Baillon. Bulliten


Agricole du Congo Belgium 1955; XLVI
(4):805-829.
[93]. Jain LD, Baheti MA, Jain RS. Khandelwal R.K.,
Use of medicinal plants among tribes in
Satpuda region of Dhule and Jalgaon districts
of Maharashtra-An Ethanobotanical survey.
Indian Journal of Traditional Knowledge
2010;9(1):152-157.
[94]. Singh KP, Singh PA, Gupta KA, Chaudhary S.
Beneficial effects of aqueous fruit extract of
Tribulus terrestris on testicular and serum
biochemistry of albino rats. J. Ecophysiol.
Occup. Hlth. 2009;9:217-223.
[95]. Saudan C, Baume N, Emery C, Strahm E, Saugy
M. Short term impact of Tribulus terrestris
intake on doping control analysis of
endogenous steroids. Forensic Science
International 2008; 178(1): e7-e10.
[96]. Gauthaman K, Adaikan PG, Prasad RN.
Aphrodisiac properties of Tribulus terrestris
extract (protodioscin) in normal and castrated
rats. Life Sci. 2002;71: 1385-1396.
[97]. Neychev VK, Mitev VI. The aphrodisiac herb
Tribulus terrestris does not influence the
androgen production in young men. J.
Ethnopharmacol. 2005;101: 319-323.
[98]. Subramoniam A, Madhavachandran V,
Rajasekharan S, Pushpangadan P. Aphrodisiac
property of Trichopus zeylanicus extract in
male mice. J of Ethanopharmacology 1997;
57(1): 21-27.
[99]. Kumar S, Madaan R, Sharma A. Evaluation of
Aphrodisiac activity of Turnera aphrodisiaca.
International Journal of Pharmacognosy and
Phytochemical Research 2009; 1(1);1-4.
[100]. Duke JA, Rodolfo V.
Amazonian
Ethnobotanical Dictionary. CRC Press;1994.
[101]. Taylor NDL. The Healing Power of
Rainforest Herbs, Square One Publishers;2005.
[102]. Jain BJ, Kumane CS, Bhattacharya S. Medicinal
flora of Madhya Pradesh and Chattisgarh-A

review. Indian Journal of


Knowledge 2006;5(2): 237-242.

Traditional

[103]. Kumar
SKP,
Subramoniam
A,
Pushpangadan P. Aphrodisiac activity of Vanda
tessellata (roxb.) hook. ex don extract in male
mice. Indian Journal of Pharmacology
2000;(32):300-304.
[104]. Maiti S. Breakthrough and research
heighlights National research centre for
medicinal and aromatic plants. Newsletter
2008; 9(2): 4-5.
[105]. Haque R., Saha S, Bera T. A peer reviewed of
general
literature
on
Chlorophytum
borivilianum commercial medicinal plant. Int.
J. Drug Develop. Res. 2011;3(1):140-155.
[106]. Mehar A, Agrahari AK, Pradhan AR. Indian
medicinal plants Cissus quadrangularis Linn.:
an ethnobotanical and ethnomedicinal review.
Herbal Tech. Industry 2010:1-3.
[107]. Venugopal SN. Simple formulation for
primary health care uses based on Ayurveda,
FRLGHT. Report 2002:1-38.
[108]. Vandal
R.
An
investigation
of
cardioprotective activity of Citrullus lanatus
(Thunb.) seed powder suspension on
experimentally induced cardiotoxicity in rats.
B. Pharma Thesis. Rajiv Gandhi University of
Health Science 2011:Karnataka, Bangalore.
[109]. Akonidi RB, Pawar KM, Challa RS. Natural
compounds to treat male infertility.
Pharmacologyonline 2009 ;(2): 240-251.
[110]. Siddiqui MZ. Guggul: an excellent herbal
panacea. Asian Pharm. Health Sci. 2011, 3539.
[111]. Mohammed S, Kasera PK, Shukla JK.
Unexploited plants of potential medicinal
values from the Indian Thar Desert. NPR.
2004;3(2): 69-71.
[112]. Mathur M. Ecology and Prospecting of some
Medicinal Plants of Aphrodisiac Potential,
Ph.D. Thesis. Jai Narain Vyas University
2005;Jodhpur.

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

18

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

[113]. Kataria S, Shrivastava B, Khajuria RK. Suri


KA. Sharma P. Antimicrobial activity of
Crotalaria burhia Buch. Ham. Root. IJNPR
2010; 1(4): 481-484.
[114]. Mathur M. Herbal Aphrodisiac their Need,
Biology and Status: Global and Regional
Scenario. Journal of Natural Products2012;
(5):131-146
[115]. Jaiswal S, Singh SV, Singh B, Singh HN.
Plants used for tissue healing of animals. NPR
2004;3(4): 284-292.
[116]. Kumar RS, Rajkapoor B, Perumal P.
Antitumor and cytotoxic activites of methanol
extract of Indigofera linnaie Ali. APJCP 2011;
12: 613-618.
[117]. Patel DK, Kumar R, Prasad SK, Hemalatha S.
Pharmacologically screened aphrodisiac plantA review of current scientific literature. Asia
Pac. J. Trop. Biomed. 201; 131-138.
[118]. Jain SC, Jain R, Vlietinck AJ. In vivo and in
vitro antimicrobial efficacy of Mimosa hamata.
IJBT 2004; (3): 271-273.
[119]. Faher JW. Moringa oleifera: A review of the
medicinal evidence for its nutritional,
therapeutic and prophylactic properties. Tree
for Life Journal 2005;1(5): 1-15.
[120]. Patel DK, Kumar R, Prasad SK, Hemalatha S.
Pharmacologically screened aphrodisiac plantA review of current scientific literature. Asia
Pac. J. Trop. Biomed. 2011;131-138.
[121]. Katzenschlager R, Evans A, Manson A,
Patsalos P, Ratnaraj N, Watt H et al. Mucuna
pruriens in Parkinson disease: a double blind
clinical and pharmacological study. J. Neurol.
Neurosurg. Psychiatry. 2004;75(12):16721677.
[122]. Hukkeri VI, Akki KS, Surben RR,
Gopalakrishna B, Byahatti VV, Rasendra SN.
Hepatoprotective activity of leaves of
Nyctanthes arbor-tristis Linn. Indi. J. Pharm.
Sci. 2006; 68:542-543.

[123]. Subhan F, Sultan S, Alam W, Tahir F, Dil AS.


Aphrodisiac potential of Peganum harmala
seeds. Hamdard Medicus 1998;4:69-72
[124]. Bankole HA, Magbagbeola OA, Adu OB,
Fatai AA, James BA. Biochemical Effect of
Ethanolic Extract of Phyllanthus amarus
(Euphorbiaceae) on Plasma Nitric Oxide and
Penile Cyclic Guanosine Monophosphate
(cGMP) in Mature Male Guinea Pigs. Asian. J.
Biochem. 2011;6:291-299.
[125]. Lgwe CV, Waogu LA, Usuwondu CO.
Assessment
of
the
hepatic
effect,
phytochemical and proximate composition of
Phyllanthus amarus. AJBT 2007; (6):728-731.
[126]. Tandon VR. Medicinal uses and biological
activities of Vitex negundo. NPR. 2007;4(3):
162-165.
[127]. Mohammed S, Kasera PK, Shukla JK.
Unexploited plants of potential medicinal
value from the Indian thar desert. Nature
product radiance 2004; 3(2).
[128]. Pande M, Pathak. Sexual function
improving effect of Chenopodium album
(Bathura sag) in normal male mice .Biomed.
Pharma. J. 2008;1: 325-332.
[129]. Frotan MH, Acharya SB. Pharmacological
studies of shilaji. Indian J Pharmacol 1984:
16:45.
[130]. Available from: http: // thamilar-nalasevai.
info/ Media/ healthcare/ Male Support_eng.
pdf. [Last accessed on 2011 Nov4].
[131]. Welt K, Weiss J, Koch S, Fitzl G. Protective
effects of Ginko biloba extract EGb 761 on the
myocardium of experimentally diabetic rats. II.
Ultrastructural and immunohistochemical
investigation on microvessels and interstitum.
Exp. Toxicol. Pathol. 1999;51:213-22.
[132]. Available
from
:http//himalayahealth
care.com/herbfinder/h_ipomoea.htm.[last
accessed on 2011 Nov 4].
[133]. Gundidza M, Masuku S, Humphrey G,
Magwa ML. Anti-diabetic activity of Aloe

_____________________________________________________________________________________
Alok et al.

Int J Recent Adv Pharm Res, 2013;3(2):1-20

ISSN: 2230-9306; www.ijrapronline.com

19

International Journal of Recent Advances in Pharmaceutical Research


April 2013; 3(2): 1-20
____________________________________________________________________________________________________________________________________________

excelsa. Cent. Afr. J. Med. 2005;51(11


12):115120.
[134]. Yakubu MT, Akanji MA, Oladiji AT. Male
Sexual Dysfunction and Methods used in
Assessing Medicinal Plants with Aphrodisiac
Potentials.
Pharmacognosy
Reviews
2007;(1):1.
[135]. Cherdshewasart W, Nimsakul N. Clinical
trial of Butea superba, an alternative herbal
treatment for erectile dysfunction. Asian J.
Androl. 2003;(5): 243-246.
[136]. Malviya N, Jain S, Gupta VB, Vyas S. Recent
studies on aphrodisiac herbs for the
management of male sexual dysfunction- A
Review: Acta Poloniae Pharmaceutica-Drug
Research 2011; (68): 3-8.
[137]. Joy PP, Thomas J, Mathew S, Skaria PB.
Medicinal
Plants,
Kerala
Agricultural
University. Aromatic and Medicinal Plants
Research Station, 1998.
[138]. Thomas J, Joy PP, Mathew S, Skaria BP,
Duethi PP, Joseph TS. Agronomic Practices for
Aromatic and Medicinal Plants Kerala
Agricultural University and Directorate of
Arecanut & Spices Development (Min. of Agri.,
Govt. of India), Calicut, Kerala, India, 2000.
[139]. Singh KP, Kumar V, Tiwari KR, Sharma A,
Rao CV, Singh RH. Medico-Ethnobotany of
Chatara Block of District Sonebhadra, Uttar
Pradesh, India. Advances in Biological
Research 2010;4(1):65-80.
[140]. Augustine AC, Souza LD. Conservation of
Curculigo
orchioidesAn
endangered
anticarcinogenic herb symp. Recent advances
Biotechnol. 1995; 22-24.

[141]. Bose RC, Samuel S, Jolly CI. Male sexual


dysfunction and medicinal plants with
Aphrodisiac potentials. Kerala Ayurveda News
& Views 2008;7(2), 19-23
[142]. Yakubu MT, Akanji, MA and Oladiji, A. T
Male sexual dysfunction and methodsused in
assessing medicinal plants with aphrodisiac
potentials Pharmacognosy reviews 2007;1:
49-56.
[143]. Qarawi AA. Stimulatory Effect of the
Aqueous Extract of Ruta chalepensis on the
Sex Organs and Hormones of Male Rats. The
Journal of Applied Research 2005;5(1): 206211.
[144]. Malviya N, Jain S, GuptaVB, Vyas S. Recent
studies on aphrodisiac herbs for the
management of male sexual dysfunction-A
Review: Acta Poloniae Pharmaceutica - Drug
Research 2011;68: 3-8.
[145]. Meena KA, Yadav KA, Panda P, Preet K, Rao
MM. Review on Stereospermum suaveolens DC
: A Potential Herb. Drug Invention Today 2010;
2(5):238-239.
[146]. Zambl A, Martin-Nizard F, Sahpaz S,
Reynaert ML, Staels B, Bordet R et al. Effects of
Microdesmis keayana alkaloids on vascular
parameters of erectile dysfunction. Phytother
Res. 2009; 23(6):892-5.
[147]. Faleyimu, OI, Oso AO. Medicinal utilization
of herbs for the treatment of erectile
dysfunction in lere local government area of
Kaduna state, Nigeria. Asian Journal of Natural
& Applied Sciences 2012;(1): 2.2012.

_____________________________________________________________________________________
Alok et al.

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