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Aloe vera is celebrated for its varied pharmacological properties and therapeutic uses,
one of which being a promising treatment for certain types of cancers. A systematic
review of Aloe vera had accumulated a good amount of data from extensive literature
search on dermatology studies and clinical trials and supports the use of Aloe vera as a
candidate for photodynamic therapy of some kinds of cancer. [1]
Aloe vera also contains a substance known as 1,8-dihydroxy-3-[hydroxymethyl]anthraquinone (or simply AE), which has been proven to induce cell death among T24
cells (human bladder cancer cell line). AE has notable anticancer effects and inhibits cell
viability while stimulating the arrest of G2/M of the cell cycle. [2]
References
[1] Feily A. & Namazi M. R. (2009). Aloe vera in dermatology: a brief review. Giornale
Italiano di Dermatologia e Venereologia, 144(1): 85-91. Retrieved 7 June 2013
from http://www.ncbi.nlm.nih.gov/pubmed/19218914
[2] Lin J. G. et al. (2006). Aloe-emodin induces apoptosis in T24 human bladder cancer
cells through the p53 dependent apoptotic pathway. Journal of Urology, 175(1): 343-347.
Retrieved 7 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/16406939
Ammania Vesieatoria
Ammania Vesieatoria is an obscure East Indian aquatic plant. The leaves are very acrid,
and are sometimes used as blisters. Source - http://books.google.com/books?
id=CzsoAAAAYAAJ&pg=PA759&lpg=PA759
Ammania Vesieatoria is an ingredient in Carctol, an Ayurvedic herbal preparation that
has been used as an anticancer treatment. Carctol is under strict legal restrictions in the
UK although the web site claims it has passed 'strict toxology tests'. Source
- http://www.carctolhome.com/introduction.php
Retrieved
June
2013
Artemisia annua
Artemisia annua, also known as sweet wormwood, sweet annie, sweet fern, sweet
sagewort, or annual wormwood, [1] sprang to fame as a possible anticancer herb in 2001
when two researchers at the University of Washington noted that wormwood showed
highly selective activity against breast cancer cells. [2]
In more recent research, artemisinin, a compound extracted from A. annua, has been
demonstrated to have activity against malaria and cancer cells [3][4] and to inhibit a
number of viruses, including herpes simplex 1 and hepatitis B and C. [5]
Artemisinin and its derivatives have been shown to induce apoptosis of prostate cancer
cells and to possess activity against breast cancer, leukemia, colon cancer, and other
cancer cells. [6] A significant body of scientific research investigating the anticancer
properties of Artemisia annua has been performed since 2008, which indicated the
potential for development of both therapeutic and preventative treatments.
(See herbs-info.com's full Artemisia article)
References
[1]
Artemisia
annua.
Wikipedia.
from http://en.wikipedia.org/wiki/Artemisia_annua
Retrieved
June
2013
2013
[4] Schaller J. (2006).The use of the herb artemisinin for babesia, malaria, and cancer:
All the practical information you need to make smart decisions on artemisinin.
CreateSpace.
Retrieved
4
June
2013
from http://books.google.com.ph/books/about/The_Use_of_the_Herb_Artemisinin_for_B
abe.html?id=IA6pBAAACAAJ
[5] Blazquez A. G. et al. (2013). Novel artemisinin derivatives with potential usefulness
against liver/colon cancer and viral hepatitis. Bioorganic & Medicinal Chemistry, pii:
S0968-0896(13)00385-4. doi: 10.1016/j.bmc.2013.04.059. Retrieved 4 June 2013
from http://www.ncbi.nlm.nih.gov/pubmed/23685181
Baptisia
Baptisia, also known as wild indigo, is a perennial indigenous to New England. As it
thrives in dry soil, it does not grow around streams or in areas of high precipitation.
Baptisia has a high polysaccharide content, which makes it an immunomodulator (it
stimulates the immune system). Applied topically, Baptisia soothes inflammation and
reduces redness. Historically, Baptisia was used as a natural antibiotic in the treatment of
both internal and external infections. Herbalists and homeopaths continue to use
Baptisia to treat a wide range of imbalances in the body. Baptisia promotes a sense of
mental clarity, motivation, and emotional well-being, all of which are seen as necessary
components in a holistic healing program.
As a decongestant for the lymph and other drainage systems, Baptisia is best prepared
as an infusion or in a tea with complementary herbs. Whole dried Baptisia herb can be
prepared as an infusion, or the whole herb can be coarsely ground and brewed as looseleaf tea or finely ground and administered in capsules made of vegetable cellulose.
Although traditionally a mortar and pestle was used to grind the Baptisia herb, a coffee
grinder will suffice.
[2]
Liver
cancer
herbal
treatment.
Retrieved
5
June
2013
from http://www.mahaaushadhi.com/info/ayurveda/digestivesystem/liver-cancer-herbaltreatment.html
[3] Ho Y. T. et al. (2009). Berberine induced apoptosis via promoting the expression of
caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human
tongue squamous carcinoma cancer cells. Anticancer Research, 29(10): 4063-4070.
Retrieved 5 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/19846952
[4] Chamberlain J. (2008). Cancer: The complete recovery guide: Everything that
everyone should know about cancer and how to recover from it. USA: Long Island Press.
Retrieved
5
June
2013
from http://books.google.com.ph/books/about/Cancer_The_Complete_Recovery_Guide.
html?id=lWhctJb302QC
Blackberry Bush
Blackberry bush owes much of its anticancer property to its ellagic acid content. Ellagic
acid is a phenol antioxidant that can induce cancer cell death through apoptosis
associated with decreased ATP production. More importantly however, this apoptotic
activity comes without any toxic effect on the viability of normal human lung fibroblast
cells. Ellagic acid expresses selective cytotoxicity and anti-proliferative activity as well. [1]
References
[1] Losso J. N., Bansode R. R., Trappey A., Bawadi H. A., & Truax R. (2004). In vitro antiproliferative activities of ellagic acid. Journal of Nutritional Biochemistry, 15(11): 672-678.
Retrieved 7 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/15590271
[1]
black walnut
Naturally occurring in fruits such as blackberries, anthocyanins are not produced by the
human body. While the addition of fresh blackberries, or blackberry jam, into your daily
diet can increase your body's defense against free radicals, the most efficient way to
unleash the fruit's disease-fighting power is to take blackberry extract in capsule form so
that the anthocyanins are not immediately digested (and thus will be delivered to the
gastrointestinal tract). [1]
References
[1] Roenker R. (2006). Elisting blackberries in the fight against cancer. University of
Kentucky
Odyssey.
Retrieved
5
June
2013
from http://www.research.uky.edu/odyssey/summer06/blackberries.html
Blepharis edulis
Blepharis edulis is a species of plant belonging to the family Acanthaceae and is
indigenous to the Middle East. Found today in Pakistan, India, and Egypt, it is used as
an herbal remedy in Ayurvedic (traditional Indian) medicine to treat cases of mental
confusion and nervousness. The seed of Blepharis edulis is a component of Carcatol, a
remedy used in Ayurveda to increase vitality in cancer patients.
Boswellia serrata has been studied for its anticancer properties, especially acetyl-11keto--boswellic acid (AKBA), the substance obtained from the gum resin of the said
herb. A study from the University of Texas MD Anderson Cancer Center has
demonstrated that AKBA inhibits the growth and proliferation of human pancreatic cancer
lines, induces apoptosis, and suppresses the metastasis of pancreatic cancer cells to the
spleen, liver, and lungs in an orthotopic nude mouse model. [1]
In another study, the oral administration of AKBA to mice resulted in the inhibition of
colorectal cancer growth. AKBA was also found to be highly effective against ascites
(accumulation of fluid in the peritoneal cavity) and suppressed the metastasis of the
cancer cells to the liver, lungs, and spleen in nude mice. [2]
It appears that Boswellia serrata's effectiveness against cancer lies on its ability to
regulate cellular epigenetic machinery [3] and to inhibit tumor growth and metastasis by
downregulating cancer-related biomarkers. [2]
Frankincense contains a number of compounds that hinder cancer cells from spreading
or migrating. Immunologist Mahmoud Suhail in a BBC News write-up states, "Cancer
starts when the DNA code within the cell's nucleus becomes corrupted. It seems
frankincense has a re-set function. It can tell the cell what the right DNA code should
be." [4]
A 2009 study from the University of Oklahoma Health Sciences Center had reported that
frankincense oil is effective in suppressing the viability of human bladder cancer cells,
inducing death among cancer cells. More to this, frankincense oil appears to exert its
anticancer effects without harming the normal bladder cells. [5] These findings are more
or less similar to those of a 2012 study from Long Hua Hospital Shanghai University of
Traditional Chinese Medicine, China. This Chinese study had demonstrated too that
frankincense essential oil suppresses viability and stimulates cell death among cancer
cells (in this case, human pancreatic cancer cells). Human pancreatic cancer cells seem
to be sensitive to frankincense essential oil distillate fractions with higher-molecularweight compounds. [6]
References
[1] Park B., Prasad S., Yadav V., Sung B., & Aggarwal B. B. (2011). Boswellic acid
suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude
mouse model through modulation of multiple targets. PLoS One, 6(10): e26943. doi:
10.1371/journal.pone.0026943.
Retrieved
6
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/22066019
[2] Yadav V. R. et al. (2012). Boswellic acid inhibits growth and metastasis of human
colorectal cancer in orthotopic mouse model by downregulating inflammatory,
proliferative, invasive and angiogenic biomarkers. International Journal of Cancer,
130(9):
2176-2184.
doi:
10.1002/ijc.26251.
Retrieved
24th
July
2013
from http://www.ncbi.nlm.nih.gov/pubmed/21702037
[3] Takahashi M. et al. (2012). Boswellic acid exerts antitumor effects in colorectal cancer
cells by modulating expression of the let-7 and miR-200 microRNA family.
Carcinogenesis, 33(12):
[4] Howell J. (2010). Frankincense: Could it be a cure for cancer? BBC World News.
Retrieved 15 June 2013 from http://news.bbc.co.uk/2/hi/middle_east/8505251.stm
[5] Frank M. B. et al. (2009). Frankincense oil derived from Boswellia carteri induces
tumor cell specific cytotoxicity. BMC Complementary and Alternative Medicine, 9:6. doi:
10.1186/1472-6882-9-6.
Retrieved
15
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/19296830?dopt=Citation
[6] Ni X. et al. (2012). Frankincense essential oil prepared from hydrodistillation of
Boswellia sacra gum resins induces human pancreatic cancer cell death in cultures and
in a xenograft murine model. BMC Complementary and Alternative Medicine, 12: 253.
doi:
10.1186/1472-6882-12-253.
Retrieved
15
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/23237355
Retrieved
June
2013
research indicates that Cascara sagrada not only increases vitality but also protects
against colon cancer.
Chamomile (Matricaria)
Chamomile contains chemical constituents with anticancer properties. One of these is
apigenin, a plant flavone with antioxidant and anticancer activities. It is principally linked
to a decreased cancer risk, especially to cancers of the breast, digestive tract, skin,
prostate, and blood. [1]
References
[1] Shukla S. & Gupta S. (2010). Apigenin: A promising molecule for cancer prevention.
Pharmaceutical
Research,
27(6):
962-978.
Retrieved
7
April
2013
from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874462/
June
2013
[2] Tierra M.. (2003). Treating cancer with herbs: An integrative approach. USA: Lotus
Press. Retrieved 6 June 2013 from http://books.google.com.ph/books?id=c57O-lp24H8C
indicates that it is a powerful supplier of anthocyanins, which can inhibit the growth of
tumors and existing cancer cells.
References
[1] Shifko R. (2010). Clove oil health benefits. Retrieved 6
from http://www.livestrong.com/article/116469-clove-oil-health-benefits/
June
2013
[2] Peirce A. (1999). The American Pharmaceutical Association practical guide to natural
medicines.
NY:
HarperCollins.
Retrieved
6
June
2013
from http://books.google.com.ph/books/about/The_Apha_Practical_Guide_to_Natural_M
edi.html?id=AUaleKfk3kQC
Reference
[1] Fugh-Berman, Adriane. 2003. The 5-Minute Herb and Dietary Supplement Guide.
Lippincot Williams & Wilkins: Philadelphia, PA.
[2] Sigstedt S. C. et al. (2008). Evaluation of aqueous extracts of Taraxacum officinale on
growth and invasion of breast and prostate cancer cells. International Journal of
Oncology,
32(5):
1085-1090.
Retrieved
1
March
2013
from from
http://www.ncbi.nlm.nih.gov/pubmed/18425335
Echinacea
Of the nine different species of Echinacea, only three, namely, E. purpurea, E.
angustifolia, and E. pallida, are used in marketed products. Native to North America, E.
angustifolia was used by the Plains Indians to aid in preventing exhaustion. Other tribes
used E. angustifolia to treat headaches and sore throats.
Echinacea can be purchased in capsules, tinctures, and teas. It can also be purchased
as a liquid extract. All three commonly sold varieties of Echinacea are thought to have
antifungal, antibacterial, and antiviral properties. Used to protect against sun damage,
Echinacea is thought to be effective in preventing skin cancer. E. purpurea was
commonly used by physicians to treat infections until it fell out of popularity in favor of
antibiotics. Today, Echinacea is sometimes administered by physicians to cancer patients
as a supplement to the normal course of treatment.
References
[1] Lindholm et al. (2002). Selective cytotoxicity evaluation in anticancer drug screening
of fractionated plant extracts. Journal of Biomolecular Screening, 7(4): 333-340.
Retrieved 5 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/12230887/
[2] Lpez-Lzaro M. et al. (2003). Anti-tumour activity of Digitalis purpurea L. subsp.
heywoodii. Planta Medica, 69(8): 701-704. Retrieved 5 March 2013
from http://www.ncbi.nlm.nih.gov/pubmed/14531018
[3] Lee J. Y., Woo E., & Kang K. W. (2006). Screening of new chemopreventive
compounds from Digitalis purpurea. Die Pharmazie, 61(4): 356-358. Retrieved 5 March
2013 from http://www.ncbi.nlm.nih.gov/pubmed/16649555
[3]
References
[1]
PrevPharma:
Objectives
of
company.
from http://www.prevpharma.com/company.htm
[2]
PrevPharma:
Core
technologies.
from http://www.prevpharma.com/Technology.htm
Retrieved
Retrieved
6
6
June
June
2013
2013
[3]
Phytolacca
syrup.
Cancer
Salves.
Retrieved
6
June
2013
from http://www.cancersalves.com/botanical_approaches/sms_formulas/phytolacca_syru
p.html
cancer-cell death. [2] In cases of ovarian cancer, gingerol was found to reduce
inflammation and boost immune function. It has been stated by researchers that gingerol
might protect against colon cancer. [3]
References
[1] Wichtl M. (2004). Herbal drugs and phytopharmaceuticals: A handbook for practice on
a scientific basis. Stuttgart, Germany: Medpharm Scientific Publishers. Retrieved 6 June
2013
from http://books.google.com.ph/books/about/Herbal_Drugs_and_Phytopharmaceuticals.
html?id=7PRyMWo5e28C
[2] Rhode J. et al. (2007). Ginger inhibits cell growth and modulates angiogenic factors in
ovarian cancer cells. BMC Complimentary and Alternative Medicine, 7: 44. Retrieved 6
June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/18096028
[3] Jeong C. H. et al. (2009). [6]-Gingerol suppresses colon cancer growth by targeting
leukotriene A4 hydrolase. Cancer Research, 69(13): 5584-5591. doi: 10.1158/00085472.CAN-09-0491.
Retrieved
6
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/19531649
Goldenseal
Native to North America, goldenseal has been used for centuries by indigenous peoples
to treat infections of the gums, mouth, and throat. Today, it is often used as a key
ingredient in natural toothpastes and mouthwash in order to inhibit bacterial growth and
to prevent tooth decay. Studies show that berberine, a potent compound in goldenseal,
has antibiotic properties. [1] Goldenseal is currently undergoing scientific analysis for its
potential to lower cholesterol. Low cholesterol is associated with a decreased risk for
developing certain types of cancer. [2]
References
[1] Sun Y., Xun K., Wang Y., & Chen X.. (2009). A systematic review of the anticancer
properties of berberine, a natural product from Chinese herbs. 2009. Anticancer Drugs,
20(9):
757-769.
Retrieved
6
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/19704371
[2] Efferth T. et al. (2005). Molecular determinants of response of tumor cells to
berberine. Cancer Genomics & Proteomics, 2(2): 115-124. Retrieved 6 June 2013
from http://cgp.iiarjournals.org/content/2/2/115.full.pdf
parasite infections, herpes, cough, and arthritis. [1] It often goes by the name "soursop,"
presumably because of the fruit's sour citrus flavor.
A 2012 study from the Department of Biochemistry and Molecular Biology, Omaha,
Nebraska, has shown that graviola is effective against pancreatic cells, tumor cells that
are known to be very resistant to conventional therapy. Graviola owes its ability to
eliminate cancer cells to its compounds that inhibit several signaling pathways used by
pancreatic cancer cells to regulate their metabolism, cell cycle, survival, and metastatic
properties. Because of such inhibition, the pancreatic tumors' rate to spread to other
organs and to form new cancer cell growth become remarkably slower. [2]
In another study from the Department of Food Science and Technology, Virginia Tech,
Blacksburg, Virginia, the extract from the graviola fruit had been found to inhibit the
growth of breast cancer cells. The expression of epidermal growth factor receptor
(EGFR) was also downregulated. [3] It should be noted that mutations that result in the
overexpression of EGFR have been strongly linked to a number of cancers
There has also been some controversy over Graviola due to "hyped" claims over its
cancer-killing
abilities.
These
have
been
comprehensively
discussed
here: http://www.hoax-slayer.com/soursop-cancer-cure.shtml. Here also is the original
study
that
is
behind
the
"10,000
times
stronger
than
chemo"
claim: http://www.ncbi.nlm.nih.gov/pubmed/8991944
References
[1] Find a vitamin or supplement. Graviola. WebMD. Retrieved 13 June 2013
from http://www.webmd.com/vitamins-supplements/ingredientmono-1054GRAVIOLA.aspx?activeIngredientId=1054&activeIngredientName =GRAVIOLA
[2] Torres M. P. et al. (2012). Graviola: a novel promising natural-derived drug that
inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo
through altering cell metabolism. Cancer Letters, 323(1): 29-40. doi:
10.1016/j.canlet.2012.03.031.
Retrieved
13
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/22475682
[3] Dai Y. et al. (2011). Selective growth inhibition of human breast cancer cells by
graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression.
Nutrition and Cancer, 63(5): 795-801. doi: 10.1080/01635581.2011.563027. Retrieved 13
June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21767082
Grape Seed
A research team from the University of Colorado Anschutz Medical Campus, Aurora, had
furnished evidence on the efficacy of grape seed extract against colorectal cancer. In this
study, the extract from grape seed induced the death of colorectal cancer cells. What's
more interesting is the fact that the more advanced the colorectal cancer cells were, the
better the grape seed extract suppresses and limits the growth and survival of these
cancer cells. The administration of grape seed extract was not only effective against
colorectal cancer but also safe to healthy cells of the bidy. [1]
Numerous studies have demonstrated that certain nutritive and nonnutritive
phytochemicals with potential cancer-preventive or antitumor activity can be isolated
from grape seeds. Of these compounds, proanthocyanidins are worthy of mention.
Grape seed proanthocyanidins have been found to suppress the potential of pancreatic
cancer cells to migrate or spread. [2]
Proanthocyanidins have also been reported to inhibit the process of angiogenesis
(creation of new blood vessels) induced by colon cancer and to suppress colon tumor
growth itself. [3] The proanthocyanidins in grape seed extract act against colon cancer
cells, significantly inhibiting cell viability while inducing cell death among cancer
cells. [4] Proanthocyanidins can accumulate in high amounts in the colon because they
are usually poorly absorbed along the gastrointestinal tract. [3] This is beneficial for the
body as this means that grape seed proanthocyanidins can suppress colon cancer more
efficiently in the colon.
References
[1] Derry M., Raina K., Agarwal R., & Agarwal C. (2012). Differential effects of grape
seed extract against human colorectal cancer cell lines: The intricate role of death
receptors and mitochondria. Cancer Letters, pii: S0304-3835(12)00732-X. Retrieved 15
June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/23268334
[2] Prasad R. & Katiyar S. K. (2012). Grape seed proanthocyanidins inhibit migration
potential of pancreatic cancer cells by promoting mesenchymal-to-epithelial transition
and targeting NF-?B. Cancer Letters, pii: S0304-3835(12)00474-0. doi:
10.1016/j.canlet.2012.08.003.
Retrieved
15
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/22902508
[3] Huang S. et al. (2012). Grape seed proanthocyanidins inhibit colon cancer-induced
angiogenesis through suppressing the expression of VEGF and Ang1. International
Journal of Molecular Medicine, 30(6): 1410-1416. Retrieved 15 June 2013
from http://www.ncbi.nlm.nih.gov/pubmed/23026853
[4] Engelbrecht A. M. et al. (2007). Proanthocyanidin from grape seeds inactivates the
PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line. Cancer
Letters,
258(1):
144-153.
Retrieved
15
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/17923279/
Guava (Psidium)
A study from Kyung Hee University, Seoul, Korea, had identified d-glucuronic acid,
quercetin 3-glucuronide, loganin, and xanthyletin from the butanol fraction of guava leaf
extract. The researchers of this study concluded that guava leaves could reduce lung
cancer cell metastasis and that the fraction from guava leaves can suppress the
June
2013
[3]
Introduction
to
Carctol.
Retrieved
from http://www.carctolhome.com/introduction.php
June
2013
June
2013
Liquorice Root
Liquorice (Glycyrrhiza glabra) root is one of the oldest botanical in Chinese medicine and
is most frequently used as an anti-inflammatory, antivirus, and antiulcer agent. A study
has shown that it provides protection against DNA damage that may be induced by
Medicinal Mushrooms
Medicinal mushrooms contain a wealth of bioactive compounds that exert cancerpreventive effects on the body and are themselves potentially novel anticancer agents.
These compounds have a variety of biological activities, including immunomodulating,
free radical-scavenging, anti-inflammatory, antibacterial, antifungal, antiviral,
hepatoprotective, antidiabetic, and anticancer. Because of such, it comes without
surprise that medicinal mushrooms have always played an integral role in traditional
Chinese medicine (TCM) as an herb that prevents or treats a variety of diseases,
including cancer. Modern research in fact associates the anticancer property of medicinal
mushrooms with the ability of their active constituents to intervene with intracellular
signaling pathways related to inflammation, cell differentiation and survival, apoptosis,
angiogenesis, tumor progression, and metastasis. [1]
A study from the Cancer Research Laboratory of the Methodist Research Institute,
Indianapolis, had demonstrated the therapeutic potential of medicinal mushrooms
against breast cancer. According to this study, medicinal mushrooms retard the
proliferation of highly invasive breast cancer cells by inducing cell cycle arrest at the
G2/M phase and inhibiting the expression of genes that regulate the cell cycle of cancer
cells. The ability of breast cancer cells to adhere, migrate, and invade was also
suppressed by the medicinal mushroom blend. [2]
Mushrooms belonging to the following genera have been found to be with anticancer
potential: Phellinus, Pleurotus, Agaricus, Ganoderma, Clitocybe, Antrodia, Trametes,
Cordyceps, Xerocomus, Calvatia, Schizophyllum, Flammulina, Suillus, Inonotus,
Inocybe, Funlia, Lactarius, Albatrellus, Russula, and Fomes. [3]
Numerous scientific studies (mostly from Asia) have investigated the anticancer
properties of Reishi Mushroom - Ganoderma lucidum. 122 are listed with a search of
PubMed. [4]
References
[1] Petrova R. D. (2012). New scientific approaches to cancer treatment: can medicinal
mushrooms defeat the curse of the century? International Journal of Medicinal
Mushrooms,
14(1):
1-20.
Retrieved
15
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/22339703
[2] Jiang J. & Sliva D. (2010). Novel medicinal mushroom blend suppresses growth and
invasiveness of human breast cancer cells. International Journal of Oncology, 37(6):
1529-1536. Retrieved 15 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21042722
[3] Patel S. & Goyal A. (2012). Recent developments in mushrooms as anti-cancer
therapeutics: a review. 3Biotech, 2(1): 1-15. Retrieved 15 June 2013
from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339609/
[4] Retrieved 6 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed?term=Reishi
%20mushroom%20cancer
Mistletoe
Mistletoe (Viscum album) extracts and the products from it, particularly Iscador, the most
commonly used oncological drug in Europe, have been used as part of the treatment for
cancer. In one prospective nonrandomized and randomized matched-pair study involving
10,226 cancer patients, Iscador treatment was determined to prolong the survival time of
cancer patients and to induce self-regulation. In fact, the mean survival time of the
Iscador group was around 40% longer than that of the control group. [1]
The use of mistletoe extract is also associated with better survival among cancer
patients, and a good number of studies highlighting the positive effects of mistletoe
extract on cancer patients are abundant. [2]
References
[1] Grossarth-Maticek R., Kiene H., Baumgartner S. M., & Ziegler R. (2001). Use of
Iscador, an extract of European mistletoe (Viscum album), in cancer treatment:
prospective nonrandomized and randomized matched-pair studies nested within a cohort
study. Alternative Therapies In Health And Medicine, 7(3): 57-66, 68-72, 74-76 passim.
Retrieved 7 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/11347286
[2] Ostermann T., Raak C., & Bussing A. (2009). Survival of cancer patients treated with
mistletoe extract (Iscador): A systematic literature review. BMC Cancer, 9: 451. doi:
10.1186/1471-2407-9-451.
Retrieved
7
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/20021637
of
Solanum
nigrum
(Beijing,
An
here
Retrieved
June
2013
[1] Griffiths G., Trueman L., Crowther T., Thomas B., & Smith B. (2002). Onions--a global
benefit to health. Phytotherapy Research, 16(7): 603-615. Retrieved 7 June 2013
from http://www.ncbi.nlm.nih.gov/pubmed/12410539
[2] Park J., Kim J., & Kim M. K. (2007). Onion flesh and onion peel enhance antioxidant
status in aged rats. Journal of Nutritional Science and Vitaminology (Tokyo), 53(1): 2129. Retrieved 7 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/17484375
[3] Galeone C. et al. (2006). Onion and garlic use and human cancer. American Journal
of
Clinical
Nutrition,
84(5):
1027-1032.
Retrieved
7
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/17093154
Oregano
Check out this fascinating firsthand account of an in vivo study finding strong results in
favor of Origanum onites effect on lung cancer in rats.
Poke Root
Poke root is an ingredient in Origanum onites,
treatment in the late 1900s.
[1]
Reference
[1]
Phytolacca
syrup.
Cancer
Salves.
Retrieved
6
June
2013
from http://www.cancersalves.com/botanical_approaches/sms_formulas/phytolacca_syru
p.html
[1]
Several scientific
Piper cubeba is an ingredient in Carctol, an Ayurvedic herbal preparation that has been
used as an anticancer treatment. Carctol is under strict legal restrictions in the UK
although the website claims it has passed "strict toxology tests." [3]
References
[1]
Piper
(genus).
Wikipedia.
Retrieved
from http://en.wikipedia.org/wiki/Piper_%28genus%29
[2] Retrieved 6
%20anticancer
June
2013
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed?term=piper
[3]
Introduction
to
Carctol.
Retrieved
from http://www.carctolhome.com/introduction.php
June
2013
Polygala senega
In vivo testing has confirmed that Polygala senega has the potential to protect against
chemically induced lung cancer. [1] The article can be accessed through PubMed.
References
[1] Paul S. et al. (2011). Anticancer potentials of root extract of Polygala senega against
benzo[a]pyrene-induced lung cancer in mice. Zhong Xi Yi Jie He Xue Bao, 9(3): 320-327.
Retrieved 6 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21419086
[1] The Health Experts of The Doctors' Prescription for Healthy Living. (2008). Natural
cancer cures: The definitive guide to using dietary supplements to fight and prevent
cancer. UK: Freedom Press. p.19.
[2] Cassileth B. (2010). Complementary therapies, herbs, and other OTC agents: red
clover (Trifolium pratense). Oncology (Wiliston Park), 24(10): 960. Retrieved 6 June
2013 from http://www.ncbi.nlm.nih.gov/pubmed/21138179
[3]
Ehrlich
S.
(2010).
Red
clover. University
of
Maryland
Center. http://www.umm.edu/altmed/articles/red-clover-000270.htm
Medical
June
2013
intracranial tumors but treated with Ruta, six of the seven glioma patients manifested
complete regression of tumors. [2]
References
[1] Preethi K. C., Kuttan G., & Kuttan R. (2006). Anti-tumour activity of Ruta graveolens
extract. Asian Pacific Organization for Cancer Prevention, 7(3): 439-443. Retrieved 7
June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/17059340
[2] Pathak S., Multani A. S., Banerji P., & Banerji P. (2003). Ruta 6 selectively induces
cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A
novel treatment for human brain cancer. International Journal of Oncology, 23(4): 975982. Retrieved 7 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/12963976
Saffron
The results of in vivo and in vitro experiments indicate that crocetin, a carotenoid
constituent in saffron, might have potential as an antitumor agent. [1] Saffron was found to
inhibit skin cancer in mice. [2]
References
[1] Gutheil W. G., Reed G., Ray A., Anant S., & Dhar A. (2012). Crocetin: An agent
derived from saffron for prevention and therapy for cancer. Current Pharmaceutical
Biotechnology,
13(1):173-179.
Retrieved
6
June
2013
from http://www.ncbi.nlm.nih.gov/pubmed/21466430
[2] Das I., Das S., & Saha T. (2010). Saffron suppresses oxidative stress in DMBAinduced skin carcinoma: A histopathological study. Acta Histochemica, 112(4): 317-327.
Retrieved 6 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed/19328523
Scrophularia
Scrophularia is a genus of around 200 species, several of which have found use in
herbal anticancer preparations or research. Scrophularia marilandica was used by the
Iroquois and was considered by Dr. Eli G. Jones, who had a forty-year career of treating
cancer patients, to be "the most important item in his repertoire." [1]
Some scientific studies have investigated Scrophularia for its anticancer activity:
1. http://www.ncbi.nlm.nih.gov/pubmed/15924924 (Scrophularia ningpoensis)
2. http://www.ncbi.nlm.nih.gov/pubmed/8339032 (Scrophularia ningpoensis)
3. http://www.ijpr.ir/3Db7a24b27fd5856f0882b5875009a9fa8%26fileName
%3Dfull_text.pdf (Scrophularia striata)
4. http://www.academicjournals.org/jmpr/PDF/pdf2011/4June/Azadmehr%20et%20al.pdf
(Scrophularia megalantha)
References
[1]
Retrieved
6
June
2013
from http://www.cancersalves.com/botanical_approaches/sms_formulas/seneca_elixir.ht
ml
June
2013
[2] The Health Experts of The Doctors' Prescription for Healthy Living. (2008). Natural
cancer cures: The definitive guide to using dietary supplements to fight and prevent
cancer. UK: Freedom Press. p.19
More on the Hoxsey Treatment:
1. http://web.archive.org/web/20110429092628/http://www.naturalnews.com/027020_can
cer_the_AMA_medicine.html
2. http://www.botanicaldog.com/proddetail.php?prod=Hoxsey
3. http://en.wikipedia.org/wiki/Hoxsey_Therapy
Smilax china
A few scientific studies on the action of Smilax china on cancer have been
done. [1] Smilax china is an ingredient in the product Carctol, an Ayurvedic herbal
preparation that has been used as an anticancer treatment. Carctol is under strict legal
restrictions in the UK although the website claims it has passed "strict toxology tests." [2]
References
[1] Retrieved 6 June 2013 from http://www.ncbi.nlm.nih.gov/pubmed?term=smilax
%20china%20cancer
[2]
Introduction
to
Carctol.
Retrieved
from http://www.carctolhome.com/introduction.php
June
2013
Stillingia sylvatica
To date, there are no reports associating Stillingia sylvatica use and cancer, although
one study from the Molecular Mechanisms of Tumor Promotion Section of the National
Cancer Institute in Maryland has demonstrated the ability of prostratin, a component of
S. sylvatica, to antagonize tumor promotion. [1]
References
[1] Szallasi Z., Krsmanovic L., & Blumberg P. M. (1993). Nonpromoting 12-deoxyphorbol
13-esters inhibit phorbol 12-myristate 13-acetate induced tumor promotion in CD-1
mouse skin. Cancer Research, 53(11): 2507-2512. Retrieved 7 June 2013
from http://www.ncbi.nlm.nih.gov/pubmed/8495413
Tribulus terrestris
Native to North Africa, Tribulus terrestris was first documented in the Brazilian
Pharmacopeia in 1950. [1] Scientific research indicates that T. terrestris might be
beneficial in the treatment and prevention of cancer. [2] T. terrestris is an ingredient in
Carctol, an Ayurvedic herbal preparation that has been used as an anticancer treatment.
Carctol is under strict legal restrictions in the UK although the website claims it has
passed "strict toxology tests." [3]
References
[1] Center for Mediterranean Corporation. (2005). A guide to medicinal plants in North
Africa. Malaga, Spain: International Union for Conservation of Nature and Natural
Resources Reproduction
June
2013
Retrieved
June
2013
Old herbal from Elizabeth Blackwell (1751) states white lily to have antitumor action. This
property is not mentioned by Culpeper. I did not find any related scientific studies of
Lilium album; however, a few related studies on other Lily species - of possible interest to
those doing further research - can be found: