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Biomarkers to Life.
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MILLIPLEX
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Species
Catalogue No.
Species
Catalogue No.
Adipokine
Rat
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Sepsis Panel 4
Human
HSP4MAG-63K
Adipocyte
Rat
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Sepsis Panel 5
Human
HSP5MAG-63K
Adiponectin
Rat
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Metabolic Hormone
Feline
FMHMAG-20K
Canine
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CVD Panel 2
Mouse
MCVD2MAG-77K
Liver Injury
Rat
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Cytokine/Chemokine Panel 2
Primate
PRCYTMAG2-40K
Cytokine/Chemokine Panel 2,
24-Plex Premix
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PRCYTMAG40K-PX24
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PRCYTMAG40K-PX24
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Canine
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Human
HSCRMAG-32K
PGE2
Human
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HSCRMAG32KPX14
Human
48-623MAG
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Rat
RV1MAG-26K
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Human
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Human
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Cystatin C
Rat
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HKI2MAG-99K
Human
HKI3MAG-99K
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HKI4MAG-99K
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HKI5MAG-99K
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HKI6MAG-99K
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MKI1MAG-94K
Mouse
MKI2MAG-94K
Canine
CKT1MAG-97K
GyroMark HT Kits
Species
Catalogue No.
Clusterin
Rat
GLP-1, Active
Multispecies
GYGLP1A-35K
GLP-1, Total
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GYGLP1T-36K
KIM-1
Rat
GYRKIM1-20K
Insulin
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Mouse
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GYRCLU-37K
GYRMI-13K
Catalogue No.
Catalogue No.
SPOTLIGHT
IP-10
5
0
24 h
48 h
Renin
10
5
0
24 h
48 h
48 h
72 h
15
5
0
Vehicle
Cisplatin
10
*
24 h
TIMP-1
48 h
72 h
VEGF
Vehicle
Cisplatin
6
4
2
24 h
KIM-1
20
72 h
Vehicle
Cisplatin
10
ng/mg uCr
ng/mg uCr
5
0
Vehicle
Cisplatin
10
72 h
15
0.25
ng/mg uCr
10
15
ng/mg uCr
ng/mg uCr
Vehicle
Cisplatin
ng/mg uCr
-2-Microglobulin
15
0.25
Vehicle
Cisplatin
0.15
0.10
0.05
24 h
48 h
72 h
0.00
24 h
48 h
72 h
merckmillipore.com/bmia
SPOTLIGHT
Species
Clusterin
Rat
GLP-1, Active
Catalogue No.
GYRCLU-37K
NEW!
Multi-species
GYGLP1A-35K
NEW!
GLP-1, Total
Multi-species
GYGLP1T-36K
NEW!
KIM-1
Rat
GYRKIM1-20K
NEW!
Insulin
Rat/Mouse
GYRMI-13K
NEW!
Insulin
Human
Coming Soon!
Glucagon
Human
Coming Soon!
-2-Microglobulin
Rat
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Cystatin C
Rat
Coming Soon!
ELISA (ng/mL)
Rat/Mouse Insulin
3.5
3
2.5
2
1.5
y = 1.3302x - 0.031
R = 0.9787
1
0.5
0
0.5
1.5
2.5
Gyros (ng/mL)
Standards (recombinant proteins validated to World Health Organization standards, when available)
Quality Controls (low, middle and high concentration values to confirm kit performance)
Capture and Detection Antibody Pairs (selected for optimal performance)
Preloaded CD (produced by Gyros)
2
merckmillipore.com/bmia
MILLIPLEX
map
CIRCULATING
merckmillipore.com/bmia
BO NE / C A NCER / CVD
Cardiovascular
Human Bone
Osteocalcin (OC)
BNP
FABP4
DKK1
Osteopontin (OPN)
Cathepsin D
NT proBNP
LIGHT
FGF-23
Osteoprotegerin
(OPG)
Ferritin
CK-MB
Oncostatin (OSM)
LIX/CXCL6/GCP-2
Galectin 3
CXCL16
Placental Growth
Factor (PLGF)
IGFBP3
Endocan-1 (ESM-1)
FABP3
IL-1
IL-6
Insulin
Leptin
PTH
SOST
TNF
Cancer Biomarkers
Human Circulating Cancer
Biomarker Panel 1
(Cat. No. HCCBP1MAG-58K)
AFP
IL-8/CXCL8
CA125
Leptin
CA15-3
MIF
CA19-9
Osteopontin (OPN)
CEA
Prolactin
CYFRA21-1
PSA (free)
sFas
PSA (total)
sFasL
SCF
FGF-2/FGF-basic
TGF
HCG
TNF
HE4
TRAIL
HGF
VEGF-A
IL-6
ADAMTS13
GDF-15
D-dimer
sICAM-1
GDF15
TRAP
Lipocalin-2/NGAL
NSE
TWEAK
Osteonectin
(SPARC)
YKL40
Osteoprotegerin
(OPG)
HB-EGF
BMP-9
HGF
EGF
IL-8/CXCL8
Endoglin
Leptin
Endothelin-1
Placental Growth
Factor (PLGF)
FGF-1/FGF-acidic
FGF-2/FGF-basic
Follistatin
G-CSF
Myeloperoxidase
(MPO)
Myoglobin
Serum Amyloid A
sP-Selectin
sVCAM-1
sL-Selectin
AGP
Platelet Factor 4
(PF4)
CRP
Fetuin A
Fibrinogen
Serum Amyloid P
von Willebrand
Factor (vWF)
VEGF-A
sE-Selectin
Pentraxin-3 (PTX3)
VEGF-C
Follistatin (FST)
VEGF-D
dPAPP-A
Thrombomodulin
sPECAM-1
Troponin T (TnT)
Human Apolipoproteins
(Cat. No. APOMAG-62K)
merckmillipore.com/bmia
Periostin
Antithrombin III
Vitronectin
DKK1
Troponin I (TnI)
Myeloperoxidase (MPO)
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RANKL
ACTH
HUMAN
Bone Metabolism
Apo AI
Apo CII
Apo AII
Apo CIII
Apo B
Apo E
Human Th17
(Cat. No. HTH17MAG-14K)
(Cat. No. HT17MG-14K-PX25)
29
HCC-1/CCL14
M-CSF
GM-CSF
IL-17E/IL-25
30
IL-11
MIG/CXCL9
IFN
IL-17F
38
IL-29/IFN1
MIP-3/CCL20
IL-1
IL-21
41
I-TAC/CXCL11
MIP-3/CCL19
IL-2
IL-22
NAP-2/CXCL7
IL-4
IL-23
IL-5
IL-27
IL-6
IL-28A
IL-9
IL-31
IL-10
IL-33
13
IL-12 (p70)
MIP-3/CCL20
21
IL-13
TNF
TNF/LTA
sCD40L
IL-9
LIX/CXCL6/GCP-2
EGF
IL-10
Lymphotactin/XCL1
Eotaxin/CCL11
IL-12 (p40)
FGF-2/FGF-basic
IL-12 (p70)
Flt3 ligand
IL-13
IL-17A
GM-CSF
IP-10/CXCL10
IL-15
GRO
MCP-1/CCL2
GM-CSF
IL-13
IL-17A
IFN2
MCP-3/CCL7
IFN
IL-17A
IFN
MDC/CCL22
IL-1
IL-21
IL-1
MIP-1/CCL3
IL-2
IL-23
IL-1
MIP-1/CCL4
IL-4
ITAC
IL-1ra
PDGF-AA
IL-5
MIP-1/CCL3
sCD137
IL-5
IL-2
PDGF-AB/BB
IL-6
MIP-1/CCL4
sFas
IL-6
IL-3
RANTES/CCL5
IL-7
MIP-3/CCL20
sFasL
IL-10
IL-4
TGF
IL-8/CXCL8
TNF
GM-CSF
IL-13
IL-5
TNF
IL-10
Granzyme A
MIP-1/CCL3
IL-6
TNF/LTA
Granzyme B
MIP-1/CCL4
IL-7
VEGF-A
IFN
Perforin
IL-2
TNF
IL-8/CXCL8
I-309/CCL1
BCA-1/CXCL13
LIF
CTACK/CCL27
ENA-78/CXCL5
23
sRAGE
sgp130
sTNF RI
MCP-2/CCL8
sIL-1RII
sVEGF R1
MCP-4/CCL13
sIL-2R
sVEGF R2
Eotaxin-2/CCL24/
MPIF-2
MIP-1/MIP-5/
CCL15
sIL-4R
sVEGF R3
Eotaxin-3/CCL26
SCF
IL-16
SDF-1/CXCL12
IL-20
TARC/CCL17
IL-21
TPO
IL-23
TRAIL/TNFSF10
IL-28A
TSLP
MMP-3
MMP-13
MMP-12
MMP-9
MMP-2
MMP-10
MMP-7
TIMP-1
TIMP-2
For Research Use Only.
IL-33/NF-HEV
(mature)
17
14
sEGFR
sTNF RII
25
IL-4
sCD30
sIL-1RI
Immunology
Immunology/Immune Response
merckmillipore.com/bmia
I M M U NO LO GY / M ETA BO LISM
Immunology/Immune
Response, continued
Human Liver Protein
Human Skin
AFP
FGF-19
TIMP-3
Fibronectin
Keratin-1,10
ANGPTL3
FGF-21
TIMP-2
TIMP-4
Human Serum
Albumin (HSA)
Keratin-6
ANGPTL4
FGF-23
LPS
ANGPTL6
HGF
Involucrin
Human Immunoglobulin
Isotyping
FABP1
Metabolism/
Endocrinology
IgG3
IgG1
IgG4
IgG2
IgM
IGFBP5
IGFBP2
IGFBP6
Serum/Plasma samples
(Cat. No. HADK1MAG-61K)
IGFBP3
IGFBP7
Adiponectin
PAI-1 (total)
Adipsin
Resistin
IGFBP4
Human IGF
(Cat. No. HIGFMAG-52K)
IGF-1
IGF-2
Serum/Plasma samples
(Cat. No. HADK2MAG-61K)
sFas
MIF
sFasL
PAI-1 (total)
HGF
Leptin
ACTH
GH
sICAM-1
sVCAM-1
IL-1
MCP-1/CCL2
AGRP
LH
IL-6
NGF
CNTF
TSH
IL-8/CXCL8
TNF
FSH
HSP70
MIP-1/CCL4
Human Adipocyte
IL-1
MMP-8
MCP-1/CCL2
HGF
NGF
IL-1
PAI-1 (total)
Lactotransferrin (LTF)
IL-6
Resistin
Lipocalin-2/NGAL
IL-8/CXCL8
TNF
Leptin
Thrombospondin-1 (TSP-1)
NEW!
Olfactomedin-4
(OLFM-4)
Proteinase-3
(PRTN-3)
merckmillipore.com/bmia
Amylin (active)
IL-6
Amylin (total)
Insulin
C-Peptide
Leptin
Ghrelin (active) %
MCP-1/CCL2
GIP (total)
Pancreatic
Polypeptide
GLP-1 (active)
NEW!
GLP-1 (total)
Glucagon
Prolactin
** To be discontinued
Resistin
Insulin
Granzyme B
IL-8/CXCL8
Lipocalin-2/NGAL
TIMP-1
Cortisol
PYY (total)
TNF
Human Neurodegenerative
Disease Panel 1
-2-Macroglobulin Complement C3
Apo AI
Apo CIII
Apo E
Complement Factor
H (CFH)
-1-Acid
Glycoprotein (AGP)
Ceruloplasmin (CP)
Contactin-1
Complement C4
PEDF
Fetuin A
CRP
SAP
Kallikrein-6
NEW!
KIM-1
Serum Amyloid P
FABP1
Osteopontin (OPN)
GST
PTH
IP-10
Renin
-1-Antitrypsin
EGF
Serum/Plasma samples
(Cat. No. HKI4MAG-99K)
Osteopontin (OPN)
Soluble Superoxide
Dismutase 1
(sSOD1)
Soluble Superoxide
Dismutase 2
(sSOD2)
NEW!
-1-Microglobulin
Osteoactivin
Collagen IV
TIMP-1
GST
Uromodulin
Lipocalin-2/NGAL
Human Neurodegenerative
Disease Panel 3
Human Neuropeptide
Serum/Plasma samples
(Cat. No. HKI6MAG-99K)
BDNF
PAI-1 (total)
-MSH
Neurotensin
Cathepsin D
PDGF-AA
-Endorphin
Orexin A
-2-Microglobulin
Cystatin C
sICAM-1
PDGF-AB/BB
Cortisol
Oxytocin
Clusterin
RBP4
MPO
RANTES
Melatonin
Substance P
sNCAM
sVCAM-1
Serum samples
(Cat. No. HKTX1MAG-38K) **
Toxicity
CSF samples
(Cat. No. HNDG4MAG-36K)
sRAGE
A1-42
S100B
GDNF
Urine samples
(Cat. No. HKI1MAG-99K)
NEW!
Serum samples
(Cat. No. HKTX2MAG-38K) **
Osteoactivin
FABP1
Renin
-2-Microglobulin
GST
TFF-3
Clusterin
GST
TIMP-1
Cystatin C
IP-10/CXCL10
NGF
Tau (Thr231)
Neuron-Specific
Enolase (NSE)
Tau (total)
Urine samples
(Cat. No. HKI2MAG-99K)
Urine samples
(Cat. No. HKTX3MAG-38K) **
KIM-1
NEW!
TFF-3
Renin
-1-Microglobulin
EGF
Albumin
Lipocalin-2/NGAL
Clusterin
Osteopontin (OPN)
Urine samples
(Cat. No. HKTX4MAG-38K) **
Cystatin C
Albumin
Cystatin C
-2-Microglobulin
Osteopontin (OPN)
Clusterin
Collagen IV
Renin
Osteopontin (OPN)
KIM-1
PARK7/DJ1
KIM-1
Calbindin
-Synuclein
PARK5/UCHL1
NEW!
Human Neurodegenerative
Disease Panel 4
A1-40
Human
Human Neurodegenerative
Disease Panel 2
Haptoglobin (HP)
Prealbumin
Neuroscience
NEW!
Uromodulin
RBP4
merckmillipore.com/bmia
Non-Human Primate
Cytokine/Chemokine
(Cat. No. PRCYTOMAG-40K)
(Cat. No. PCYTMG-40K-PX)
sCD40L
IL-12/23 (p40)
G-CSF
IL-13
GM-CSF
IL-15
IFN
IL-17A
IL-1
IL-18
IL-1ra
MCP-1/CCL2
IL-2
MIP-1/CCL3
IL-4
MIP-1/CCL4
IL-5
TGF
IL-6
TNF
IL-8/CXCL8
VEGF-A
23
sCD137
IL-117E/IL-25
Eotaxin/CCL11
IL-21
sFasL
IL-22
FGF-2/FGF-basic
IL-23
Bone Metabolism
Non-Human Primate
Metabolic Hormone
ACTH
Osteocalcin (OC)
DKK-1
Osteoprotegerin
(OPG)
Amylin (active)
Insulin
C-Peptide
Leptin
IL-6
Ghrelin (active) %
MCP-1/CCL2
Insulin
GIP (total)
Pancreatic
Polypeptide
Leptin
IL-6
SOST
TNF
PYY (total)
TNF
24
25
ACTH
GH
AGRP
LH
CNTF
TSH
FSH
Prolactin
Cancer Biomarkers
Mouse Angiogenesis / Growth
Factor Panel 1
(Cat. No. MAGPMAG-24K)
sALK-1
IL-6
Amphiregulin
IL-17A
Angiopoietin-2
KC/CXCL1
Betacellulin
Leptin
sCD31/sPECAM-1 MCP-1/CCL2
EGF
MIP-1/CCL3
Endoglin
PLGF-2
Fractalkine/CX3CL1 IL-28A
Endothelin-1
Prolactin
Granzyme A
IL-31
sFASL
SDF-1
Granzyme B
IL-33
FGF-2
TNF
IL-1
IP-10/CXCL10
Follistatin
VEGF-A
IL-2
MIP-3/CCL20
G-CSF
VEGF-C
IL-4
Perforin
HGF
VEGF-D
IL-6
RANTES/CCL5
IL-1
IL-16
TNF/LTA
IL-17A
Mouse Bone
FGF-23
Glucagon
Non-Human PrimateCytokine/
NEW!
Chemokine Panel 2
(Cat. No. PRCYT2MAG40K)
(Cat. No. PRCYTMAG40K-PX24)
(Cat. No. PRCYTMAG40K-PX25)
Metabolism/
Endocrinology
GLP-1 (active)
IL-10
Primate
Immunology
merckmillipore.com/bmia
Immunology/Immune Response
Mouse CVD1
PAI-1 (total)
sE-Selectin
sP-Selectin
sICAM
Thombomodulin
MMP-9
Mouse CVD2
(Cat. No. MCVD2MAG-77K)
NEW!
sCD30
sRAGE
sgp130
sTNF RI
Eotaxin/CCL11
IL-13
sIL-1RI
sTNF RII
G-CSF
IL-15
sIL-1RII
sVEGF R1
GM-CSF
IL-17A
sIL-2R
sVEGF R2
IFN
IP-10/CXCL10
sIL-4R
sVEGF R3
sIL-6R
Oncostatin-M
IL-1
KC/CXCL1
CXCL16
Placental Growth
Factor (PLGF-2)
IL-1
LIF
IL-2
LIX/CXCL6/GCP-2
Troponin I
Mouse Th17
IL-3
MCP-1/CCL2
Troponin T
IL-4
M-CSF
IL-5
MIG/CXCL9
sCD40L
IL-17E/IL-25
IL-6
MIP-1/CCL3
GM-CSF
IL-17F
IL-7
MIP-1/CCL4
IFN
IL-21
IL-9
MIP-2/CXCL2
IL-1
IL-22
IL-10
RANTES/CCL5
IL-2
IL-23
IL-12 (p40)
TNF
IL-4
IL-27
IL-12 (p70)
VEGF-A
IL-5
IL-28B
IL-6
IL-31
IL-10
IL-33
IL-12 (p70)
MIP-3/CCL20
IL-13
TNF
TNF/LTA
Endocan-1
FABP4
Follistatin
LIGHT
Lipocalin-2/NGAL
Pentraxin-3 (PTX3)
CRP
-1-Acid
glycoprotein (AGP)
Haptoglobin
-2-Macroglobulin
Serum Amyloid P
MCP-5/CCL12
IL-15
IL-22
MIP-3/CCL20
IL-17A
IL-17E/IL-25
MIP-3/CCL19
IL-28B
TARC/CCL17
25
MOUSE
sCD40L
CVD / IM M U NO LO GY
Cardiovascular
IL-33
IL-23
MDC/CCL22
IL-27
TIMP-1
merckmillipore.com/bmia
Metabolism/
Endocrinology
Mouse Adipokine
15
Serum/Plasma samples
(Cat. No. MADKMAG-71K)
sCD137
IL-5
IL-6
PAI-1 (total)
sFas
IL-6
Insulin
Resistin
sFasL
IL-10
Leptin
TNF
GM-CSF
IL-13
MCP-1/CCL2
Granzyme B
MIP-1/CCL4
IFN
RANTES/CCL5
Mouse Adipocyte
IL-2
TNF
IL-4
Rat/Mouse Neuropeptide
(Cat. No. RMNPMAG-83K) n
-MSH
Orexin A
-Endorphin
Oxytocin
Neurotensin
Substance P
Toxicity
Mouse Kidney Injury Panel 1
Urine samples
(Cat. No. MKI1MAG-94K)
-2-Microglobulin
Renin
PAI-1 (total)
IP-10/CXCL10
TIMP-1
IL-6
Resistin
Serum/Plasma samples
(Cat. No. MMMP1MAG-79K)
KIM-1
VEGF-A
Leptin
TNF
MMP-8
MMP-3
MMP-12
Serum/Plasma samples
(Cat. No. RBN1MAG-31K)
Glucagon
IgA
IgG2b
IgG1
IgG3
IgG2a
IgM
merckmillipore.com/bmia
Bone Metabolism
Pancreatic
Polypeptide
GLP-1 (active)
Osteopontin (OPN)
EGF
GIP (total)
IL-6
PYY (total)
Resistin
TNF
ACTH
Osteocalcin (OC)
DKK1
Osteoprotegerin
(OPG)
FGF-23
Insulin
Leptin
Insulin
NEW!
Lipocalin-2/NGAL
MCP-1/CCL2
MMP-12
Cystatin C
Leptin
MMP-3
NEW!
Clusterin
C-Peptide 2
Ghrelin (active) %
Mouse Immunoglobulin
Isotyping
Urine samples
(Cat. No. MKI2MAG-94K)
Amylin (active)
proMMP-9
MCP-1/CCL2
MMP-2
MMP-8
10
Neuroscience
Adiponectin
MMP-2
mouse
Immunology/Immune
Response, continued
PTH
SOST
IGFBP1
IGFBP5
IGFBP2
IGFBP6
ACTH
Osteopontin (OPN)
IGFBP3
IGFBP7
DKK-1
Osteoprotegerin
(OPG)
FGF-23
Mouse Pituitary
Insulin
Leptin
ACTH
LH
BDNF
Prolactin
FSH
TSH
GH3
PTH
SOST
Osteocalcin (OC)
RANKL
Metabolism/
Endocrinology
Neuroscience
Rat Adipokine
Serum/Plasma samples
(Cat. No. RADPKMAG-80K)
27
Rat/Mouse Neuropeptide
EGF
IL-12 (p70)
IL-1
MCP-1/CCL2
Eotaxin/CCL11
IL-13
IL-6
PAI-1 (active)
Insulin
PAI-1 (total)
G-CSF
IL-18
Leptin
TNF
GM-CSF
IP-10/CXCL10
GRO/KC/CINC-1
Leptin
Rat Adipocyte
IFN
LIX/CXCL6/GCP-2
IL-1
MCP-1/CCL2
IL-1
MIP-1/CCL3
Adiponectin
PAI-1 (active)
IL-2
MIP-2/CCL8
IL-1
PAI-1 (total)
IL-4
RANTES/CCL5
IL-6
TNF
IL-5
TNF
Leptin
IL-6
VEGF-A
NEW!
Serum/Plasma samples
(Cat. No. RADPNMAG-81K-01)
Adiponectin
IgG2c
IgG2a
IgM
Insulin
C-Peptide 2
Leptin
Ghrelin (active) %
MCP-1/CCL2
GIP (total)
Pancreatic
Polypeptide
GLP-1 (active)
Glucagon
IL-6
PYY (total)
TNF
ACTH
LH
BDNF
Prolactin
FSH
TSH
GH
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Corticosterone
Rat Thyroid
Calbindin
KIM-1
Clusterin
Osteopontin (OPN)
GST
TIMP-1
IP-10/CXCL10
VEGF-A
NEW!
Urine samples
(Cat. No. RKTX2MAG-37K)
AGP
Cystatin C
Albumin
EGF
-2-Microglobulin
Lipocalin-2/NGAL
NEW!
Caveolin-1
PAI-1 (total)
CINC-1/GRO/KC
TIMP-1
CTGF (Connective
Tissue Growth
Factor)
TNF
VEGF-A
TSH
NEW!
von Willebrand
Factor (vWF)
sICAM-1
NEW!
Fibrinogen
Haptoglobin
Urine samples
(Cat. No. RKTX1MAG-37K)
sE-Selectin
Substance P
MCP-1
Neurotensin
IL-6
Rat Pituitary
ACTH
Oxytocin
rat
IgG1
IgE
-Endorphin
IgG2b
Orexin A
IgA
-MSH
Toxicity
Rat Adiponectin
IL-10
Immunology/Immune
Response
T4
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11
Immunology
Immunology
Immunology
13
GM-CSF
IL-15
sFas
IL-13
GM-CSF
IL-6
IFN
IL-18
FLt3 ligand
IL-18
IFN
IL-8/CXCL8
IL-2
IP-10/CXCL10
GM-CSF
KC
IL-1
IL-10
IL-6
KC-like
IFN
MCP-1/CCL2
IL-1ra
IL-12
IL-7
MCP-1/CCL2
IL-1
PDGF-BB
IL-1
IL-18
IL-8/CXCL8
TNF
IL-2
RANTES
IL-2
TNF
IL-4
SCF
IL-4
IL-6
SDF-1
IL-8/CXCL8
TNF
IL-10
Metabolism/
Endocrinology
Amylin (total)
Insulin
Ghrelin (active) %
Leptin
GIP (total)
Pancreatic
Polypeptide
GLP-1 (active)
Glucagon
PYY (total)
Leptin
GIP (total)
Pancreatic
Polypeptide (PP)
Glucagon
Prolactin
FSH
TSH
NEW!
Ghrelin (active) %
TGF1
Insulin
GLP-1 (active)
LH
Amylin (active)
Canine Pituitary
ACTH
Metabolism/
Endocrinology
PYY (total)
TGF3
TGF2
Metabolism/
Endocrinology
Multi-species Steroid/Thyroid
Hormone
GH
Toxicity
Cortisol
T3
Estradiol
T4
Progesterone
NEW!
Clusterin
Lipocalin-2/NGAL
Cystatin C
MCP-1
KIM-1
Osteopontin (OPN)
IL-8/CXCL8
12
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Immunology
IL-12 (p40)
other
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Intracellular Multiplex
Assays
Phosphoprotein and Total Detection
New Challenges, Faster Answers
Your research can take you from studying circulating to
intracellular biomarkers or even both at the same time.
This is where our MILLIPLEX map intracellular multiplex
panels and MAPmate single plex assays help.
Multiplexing, using the Luminex xMAP platform,
provides faster answers to your intracellular questions
compared to traditional Western blots, mass spectrometry
and radioactive phosphorylation assays that require large
amounts of sample.
We proudly offer the widest range of analytes and
techniques in our MILLIPLEX map intracellular portfolios.
Directly compare the total vs. phosphoprotein levels
in your assay by reading them in the same well
Conduct these measurements using minimal sample
volumes
INTRACELLULAR
Q
uickly measure levels of multiple proteins within
panels using small samples
Plex up to 8 individual MAPmate kits to design your
own custom assays using our Cell Signaling Buffer
and Detection Kit*
Plex additional MAPmate kits into existing
MILLIPLEX map Cell Signaling kits*
Use tubulin or GAPDH as housekeeping/loading
controls by plexing into an existing MILLIPLEX map
Cell Signaling kit*
*Refer to the guidelines provided in the protocols. Buffer
compatibility information is available in this publication.
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ENO1
G6PI
Analyte
HIF-1
Akt
LDHA
Akt
Total
Phosphorylated
3 (Ser473)
LDHB
PKM2
TKT
Analyte
Total
Erk/MAPK 1/2
Erk/MAPK 1/2
Phosphorylated
3 (Thr185/Tyr187)
Analyte
JNK
JNK
3 (Thr183/Tyr185)
3
Analyte
STAT3
STAT3
Catalase
INTRACELLULAR
Phosphorylated
PRX2 (PRDX2)
SOD1
SOD2
TRX1
Total
PDH
Phosphorylated
3
PDH
3 (Ser232)
PDH
3 (Ser293)
PDH
3 (Ser300)
14
Total
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Total
Phosphorylated
3 (Tyr705)
Analyte
Total
Phosphorylated
Analyte
Akt
3 (Ser473)
Akt
3 (Ser473)
GSK3a
3 (Ser21)
BAD
3 (Ser112)
GSK3b
3 (Ser9)
Bcl-2
IGF1R
3 (Tyr1135/1136)
Active Caspase 8
IR
3 (Tyr1162/1163)
Active Caspase 9
IRS1
3 (Ser636)
JNK
3 (Thr183/Tyr185)
mTOR
3 (Ser2448)
p53
3 (Ser46)
p70S6 Kinase
3 (Thr389/412)
PTEN
3 (Ser380)
RPS6
3 (Ser235/236)
TSC2
3 (Ser939)
Total
Total
3
Cleaved PARP
GAPDH
Analyte
Total
Akt
GSK3a
GSK3b
IGF1R
IR
IRS1
mTOR
p70S6 Kinase
PTEN
RPS6
TSC2
Phosphorylated
Phosphorylated
Phosphorylated
3 (Ser70)
Active Caspase 3
Cell Signaling
Cell Signaling
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Total
Phosphorylated
Total
Phosphorylated
ATF2
3 (Thr71)
Chk1
3 (Ser345)
ErK/MAPK 1/2
3 (Thr185/Tyr187)
Chk2
3 (Thr68)
HSP27
3 (Ser78)
H2A.X
3 (Ser139)
JNK
3 (Thr183/Tyr185)
c-Jun
3 (Ser73)
MEK1
3 (Ser222)
MSK1
3 (Ser212)
p38 (SAPK2A/B)
3 (Thr180/Tyr182)
p53
3 (Ser15)
STAT1
3 (Tyr701)
MDM2
p21
p53
Analyte
EGFR
3 (Ser15)
Total
Phosphorylated
EGFR
3 (Thr654)
EGFR
3 (Thr669)
EGFR
3 (Tyr845)
EGFR
3 (Tyr1045)
EGFR
3 (Ser1047)
EGFR
3 (Tyr1068)
EGFR
3 (Tyr1086)
Total
Phosphorylated
cMet/HGFR
3 (pan Tyr)
EGFR
3 (pan Tyr)
ErbB2/HER2
3 (pan Tyr)
ErbB3
3 (pan Tyr)
ErbB4
3 (pan Tyr)
IGF1R
3 (pan Tyr)
IR
3 (pan Tyr)
Analyte
HSP27
3 (Ser78/Ser82)
3
HSP70
HSP90
Phosphorylated
HSP27
HSP60
Total
Total
cMet/HGFR
EGFR
ErbB2/HER2
ErbB3
ErbB4
IGF1R
IR
Phosphorylated
16
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Phosphorylated
Analyte
Akt
3 (Ser473)
STAT1
3 (Tyr701)
CREB
3 (Ser133)
STAT2
3 (Tyr690)
Erk/MAPK 1/2
3 (Thr185/Tyr187)
STAT3
3 (Tyr705)
NFkB
3 (Ser536)
STAT5A/B
3 (Tyr694/699)
JNK
3 (Thr183/Tyr185)
STAT6
3 (Tyr641)
p38
3 (Thr180/Tyr182)
p70S6 Kinase
3 (Thr389/412)
STAT3
3 (Ser727)
STAT5A/B
3 (Tyr694/699)
Analyte
Total
Total
Phosphorylated
Total
Phosphorylated
Total
Phosphorylated
CD3e
3 (pan Tyr)
CREB
3 (Ser133)
Erk/MAPK 1/2
3 (Thr185/Tyr187)
LAT
3 (pan Tyr)
Lck
3 (pan Tyr)
FADD
3 (Ser194)
Syk
3 (pan Tyr)
IkB
3 (Ser32)
ZAP-70
3 (pan Tyr)
IKK/b
3 (Ser177/Ser181)
NFkB
3 (Ser536)
TNFRI
TGF 6 Plex
(Cat. No. 48-614MAG) AB2
Analyte
Total
Phosphorylated
Akt
3 (Ser473)
Erk/MAPK 1/2
3 (Thr185/Tyr187)
SMAD2
3 (Ser465/467)
Analyte
Total
Cell Signaling
Phosphorylated
SMAD3
Blk
3 (Tyr389)
SMAD4
Fgr
3 (Tyr412)
TGFRII
Fyn
3 (Tyr420)
Hck
3 (Tyr411)
Lck
3 (Tyr394)
Lyn
3 (Tyr397)
Src
3 (Tyr419)
Yes
3 (Tyr421)
3 (Ser423/425)
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17
Phospho-specific and total MAPmate pairs, e.g.
total GSK3 and phospho-GSK3 (Ser9).
To select the appropriate buffer for your MAPmate
assays, please refer to the protocols, this publication
or the buffer selection tables on the website.
18
Magnetic and non-magnetic bead MAPmate assays.
MAPmate assays that require different assay
buffers.
Pan Tyr and site-specific MAPmate assays, e.g.
phospho-EGF Receptor (pan Tyr) and phospho-STAT1
(Tyr701).
More than 1 phospho-MAPmate assay for a single
target, e.g. pAkt, pSTAT3.
GAPDH and -Tubulin assays cannot be plexed with
kits or MAPmate assays containing pan Tyr assays.
Cat. No.
Species Homology
AB1
AB2
-Tubulin (Total)
46-713MAG
H,M,R
GAPDH (Total)
46-667MAG
46-601MAG
H,M,R
46-645MAG
H,M,R
46-605MAG
H,M,R
46-677MAG
H,M,R
46-675MAG
H,M,R
BAD (Ser112)
46-694MAG
H,M
BAD (Total)
46-695MAG
H,M
Caspase 3 (Active)
46-604MAG
H,M
c-Jun (Ser73)
46-622MAG
H,M,R
46-619MAG
c-Kit (Total)
46-620MAG
46-651MAG
c-Met/HGFR (Total)
46-650MAG
CREB (Ser133)
46-631MAG
H,M,R
CREB (Total)
46-632MAG
H,M,R
46-603MAG
46-606MAG
46-602MAG
H,M,R
46-609MAG
H,M,R
GSK3 (Ser9)
46-690MAG
H,M,R
GSK3 (Total)
46-689MAG
H,M,R
H2A.X (Ser139)
46-692MAG
H,M
HIF-1 (Total)
46-665MAG
H,M,R
merckmillipore.com/bmia
Cat. No.
Species Homology
AB1
AB2
HSP27 (Ser78)
46-607MAG
HSP27 (Total)
46-608MAG
46-627MAG
H,M,R
IRS1 (Total)
46-628MAG
H,M,R
IB (Ser32)
46-643MAG
IB (Total)
46-644MAG
JNK/SAPK1 (Thr183/Tyr185)
46-613MAG
H,M
JNK/SAPK1 (Total)
46-618MAG
H,M
Lck (Tyr394)
46-712MAG
H,M,R
MEK1 (Ser222)
46-670MAG
H,M,R
MEK1 (Total)
46-669MAG
H,M
mTOR (Ser2448)
46-686MAG
H,M,R
mTOR (Total)
46-685MAG
H,M,R
NFB (Ser536)
46-702MAG
NFB (Total)
46-701MAG
p21 (Total)
46-621MAG
p38/SAPK2 (Thr180/Tyr182)
46-610MAG
H,M,R
p38/SAPK2 (Total)
46-612MAG
H,M,R
p53 (Ser15)
46-663MAG
p53 (Total)
46-662MAG
p70S6K (Thr389/412)
46-629MAG
H,M,R
p70S6K (Total)
46-630MAG
H,M,R
46-656MAG
PTEN (Ser380)
46-679MAG
H,M,R
PTEN (Total)
46-678MAG
H,M,R
RPS6 (Ser235/Ser236)
46-714MAG
H,M,R
RPS6 (Total)
46-715MAG
H,M,R
Src (Tyr419)
46-710MAG
H,M,R
Src (Total)
46-709MAG
H,M,R
STAT1 (Tyr701)
46-655MAG
H,M
STAT1 (Total)
46-654MAG
H,M
STAT3 (Tyr705)
46-623MAG
H,M,R
STAT3 (Ser727)
46-624MAG
H,M,R
STAT3 (Total)
46-625MAG
H,M,R
STAT5A/B (Tyr694/Tyr699)
46-641MAG
H,M,R
46-716MAG
Tie2 (Total)
46-717MAG
46-718MAG
VEGFR2 (Total)
46-719MAG
H Human
Acceptable
M Mouse
Not Recommended
R Rat
merckmillipore.com/bmia
Recommended
INTRACELLU L A R M A Pm a te K I T S
19
Lysate Description
Cat. No.
HeLa: Unstim
47-205
HepG2: Insulin
47-227
Jurkat: Unstim
47-206
47-229
Jurkat: Anisomycin
47-207
HeLa: TNF+CalA
47-230
Jurkat: H2O2
47-208
47-231
A431: EGF
47-210
HepG2: DCA
47-232
HeLa:HS/Ars
47-211
HEK293: Serum
47-233
NIH3T3: PDGF-AB
47-213
HepG2:Unstim (2)
47-234
MCF7: IGF-1
47-216
HepG2: TGF
47-235
Daudi: IL-4
47-217
THP-1: Serum
47-236
A549: Camptothecin
47-218
HFF-1: Serum
47-237
NIH3T3: Anisomycin
47-219
HUVEC: Serum
47-238
Jurkat: Paclitaxel
47-220
HepG2: Unstim(3)
47-239
Ramos: PVD
47-224
NTERA-2: Unstim
47-241
HL-60: PVD
47-225
MCF-7: Unstim
47-242
HeLa: IFN
47-226
50-100
Lysate Description
20
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MILLIPLEX
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IL-4
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EZHIL4
IL-4
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EZMIL4
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CYT420
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EZHIL8
IL-10
Human
EZHIL10
IL-10
Mouse
EZMIL10
IL-12 (p70)
Human
EZHIL12P70
IL-13
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EZHIL13
IL-15
Human
EZHIL15
IL-17A
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EZRIL17A
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Adiponectin
10 - Pack
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EZHADP-61BK
Adiponectin
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TNF
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Adiponectin
Canine
EZCADP63K
TNF
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EZMTNFA
Human
EZHMWA-64K
TNF
Rat
RZRTNFA
Adiponectin High
Molecular Weight
10 - Pack
Amylin (active)
10 - Pack
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EZHA-52K
EZHA-52BK
Apo AIV
Human
EZHAPOA4-73K
BDNF
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Human
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C-Peptide
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a-Synuclein
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Human
EZBRAIN42
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EZBRAIN-SET
Brain Derived
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Human/Rat
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Proinsulin (total)
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Resistin
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EZHR-95K
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FGF-23
10 - Pack
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EZHFGF23-32K
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EZMFGF23-43K
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Ghrelin (active)
10 - Pack
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EZGRA-88K
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Ghrelin (total)
10 - Pack
Human
EZGRT-89K
EZGRT-89BK
Kit
Species
Adiponectin
Human
Ghrelin (total)
Rat
EZRGRT-91K
C-Peptide
Human
HCP-20K
GIP (total)
10 - Pack
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EZHGIP-54K
EZHGIP-54BK
C-Peptide
Canine
CCP-24HK
GIP (total)
10 - Pack
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Ghrelin (active)
Human
GHRA-88HK
Ghrelin (total)
Human
GLP-1 (active)
Multi-species
GLP1A-35HK
GLP-1 (total)
Multi-species
GLP1T-36HK
Glucagon
Multi-species
GL-32K
Insulin
Rat
RI-13K
Insulin
Porcine
EZRMGIP-55K
EZRMGIP-55BK
GLP-1 (active)
10 - Pack
Multi-species
EGLP-35K
EGLP-35BK
Multi-species
EZGLPHS-35K
GLP-1 (total)
10 - Pack
Multi-species
GLP-2 (total)
10 - Pack
Human/Rat
Glucagon n
Human/Rat/
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EZGLPHS-35BK
EZGLP1T-36K
EZGLP1T-36BK
Insulin Lispro
Catalogue No.
HADP-61HK
GHRT-89HK
PI-12K
LPI-16K
Human
Insulin
Rat
EZGLU-30K
Leptin
Human
EZGLU-30BK
Leptin
Multi-species
EZRMGH-45K
EZRMGH-45BK
Proinsulin
Human
HPI-15K
Human
PYY-67HK
PYY (total)
Human
PYYT-66HK
Rat/Mouse
IFN
Human
Cyt271
Insulin
10 - Pack
Human
EZHI-14K
EZHI-14BK
Insulin
10 - Pack
Rat/Mouse
EZRMI-13K
EZRMI-13BK
EZHIASF-14K
Laminin
Human
ECM310
Human
EZHL-80SK
EZHL-80BK
Leptin
10 - Pack
Mouse
EZML-82K
EZML-82BK
Leptin
10 - Pack
Rat
EZRL-83K
EZRL-83BK
Leptin
Canine
EZCL-31K
Lipocalin-2/NGAL
Mouse
EZMNGAL
Omentin-1
Human
EZH0MNTN1-29K
Pancreatic Polypeptide
10 - Pack
Human
EZHPP40K
EZHPP-40BK
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FGF-21
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24
Catalogue No.
HI-14K
SRI-13K
HL-81K
XL-85K
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Ordering Information
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DDHW00010-WW
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Merck Millipore, the M mark, Direct Detect and MILLIPLEX are registered trademarks of Merck KGaA, Darmstadt, Germany.
MAPmate is a trademark of Merck KGaA, Darmstadt, Germany.
All other trademarks belonging to third parties are the properties of their respective owners.
Lit. No. PF1089ENEU Rev. V 06/2014 MIL-180 BS GEN-14-10262-EX
2014 EMD Millipore Corporation, Billerica, MA, USA. All Rights Reserved.