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c

The word root kytos, as in cytoplasm, means


A) motion

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B)

a hollow

C)

color

D)

a thing formed

The ____________ produces an image of a specimen by passing visible


light through it.
A)

LM

B)

SEM

C)

TEM

D)

none of the above

A detailed three-dimensional view of cell structure is provided by


A)

light microscopy

B)

transmission electron microscopy

C)

scanning electron microscopy

D)

all of the above

____________ are an example of cells that are specialized for storage.


A)

epithelial cells

B)

fibroblast cells

C)

adipocytes

D)

oocytes

Which cells are designed to recognize and attack antigens?

A)

muscle cells

B)

neurons

C)

erythrocytes

D)

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leukocytes

Which of the following is not true of the plasma membrane?


A)

contains receptors for communication

B)

forms intercellular connections

C)

is a rigid sheet of molecules with little flexibility

D)

regulates material movement into and out of the cell

Extracellular fluid is also called


A)

cytosol

B)

intracellular fluid

C)

interstitial fluid

D)

cytoplasmic matrix

Plasma membranes contain all of the following except


A)

phospholipids

B)

peripheral steroids

C)

integral proteins

D)

glycolipids

Which of the following is not a protein-specific function of plasma


membranes?
A)

signal transduction

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B)

intercellular attachment

C)

enzyme activity

D)

physical isolation

All processes of moving materials across the plasma membrane are


classified as either
A)

diffusion or osmosis

B)

passive or active transport

C)

phagocytosis or pinocytosis

D)

endocytosis or exocytosis

Processes that move molecules passively across the cell membrane include
A)

diffusion

B)

bulk filtration

C)

osmosis

D)

all of the above

Diffusion is the tendency of molecules to move


A)

from a lower to a higher concentration

B)

down their concentration gradient

C)

into a cell by endocytosis

D)

out of a cell by exocytosis

Which of the following are types of endocytosis?


A)

facilitated diffusion and bulk filtration

B)

osmosis and active transport

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C)

pinocytosis and phagocytosis

D)

none of the above

A pocket formed by an inward folding of a membrane is called


A)

an evagination

B)

an invagination

C)

a secretory vesicle

D)

a vacuole

Cytosol
A)

has a high water content, with many dissolved solutes

B)

is the viscous, syruplike fluid component of cytoplasm

C)

contains carbohydrates and lipids that provide energy for the cell

D)

all of the above

Which organelles synthesize proteins?


A)

ribosomes

B)

nucleoli

C)

centrioles

D)

all of the above

Digestion and self-destruction are functions of which organelle?


A)

nucleus

B)

mitochondrion

C)

lysosome

D)

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CT

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peroxisome

Which one of the following does not accurately describe microtubules?


A)

composed of long chains of the protein tubulin

B)

largest diameter of the three components of the cytoskeleton

C)

associated with organelle movement and cell motility

D)

participate in cytoplasmic streaming and muscle contraction

Most of a cell's ATP is synthesized by membrane-bound organelles called


A)

ribosomes

B)

mitochondria

C)

lysosomes

D)

nucleoli

The rough endoplasmic reticulum functions in


A)

transport, respiration, and synthesis

B)

contraction, transport, and diffusion

C)

synthesis, storage, and transport

D)

storage, transport, and digestion

Which organelle modifies, packages, and sorts proteins for secretion or


use within the cell?
A)

Golgi apparatus

B)

lysosome

C)

endoplasmic reticulum

D)

nucleus

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The most organized level of genetic material, visible with a light


microscope only during cell division, is the
A)

histone

B)

chromatin

C)

chromosome

D)

nucleosome

Nucleoli make which of the following?


A)

smooth and rough endoplasmic reticulum

B)

ribosomal RNA and proteins

C)

histones and DNA

D)

all of the above

Which phase of a somatic cell's life cycle is the longest?


A)

prophase

B)

anaphase

C)

metaphase

D)

interphase

The correct sequence of the stages of mitosis is


A)

metaphase, anaphase, telophase, prophase

B)

prophase, anaphase, metaphase, telophase

C)

telophase, metaphase, anaphase, prophase

D)

prophase, metaphase, anaphase, telophase

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During which stage of mitosis does chromatin coil into chromosomes?


A)

metaphase

B)

telophase

C)

prophase

D)

anaphase

The two copies of DNA in duplicated chromosomes are connected at a


constricted region called the
A)

double helix

B)

centromere

C)

centrosome

D)

histone

____________ occurs when the chromosomes line up at the equatorial


plate of the cell.
A)

prophase

B)

metaphase

C)

anaphase

D)

telophase

Sister chromatids pull apart to form single-stranded chromosomes during


A)

anaphase

B)

telophase

C)

prophase

D)

metaphase

The completion of ____________ marks the end of cell division.

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B)

cytokinesis

C)

interphase

D)

anaphase

peripheral proteins are attached to the inner or outer membrane surface


integral proteins form channels that let water pass in and out of the cell
the lipid "tails" in the phospholipid bilayer form a sheet that repels water
the rigid composition of the plasma membrane forms a waterproof barrier

Of all the passive processes, the only one that does not require a concentration
gradient is
A
)
B
)
C
)
D
)

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prophase

The plasma membrane is effective in isolating the cytoplasm from the


extracellular fluid primarily because
A
)
B
)
C
)
D
)

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A)

diffusion
osmosis
bulk filtration
facilitated diffusion

A transport or carrier protein


A
)
B
)
C
)
D
)

spans the plasma membrane completely and is thus a transmembrane


protein
has an internal hydrophobic region and hydrophilic regions at both ends
may use energy from ATP to help a particular substance cross the
plasmalemma
all of the above

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What must happen when a concentration gradient is eliminated?


A
)
B
)
C
)
D
)

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active transport begins


diffusion and osmosis stop
all of the above

Which one of the following processes can only occur in a living cell?
A
)
B
)
C
)
D
)

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molecular motion ceases

diffusion
osmosis
bulk filtration
endocytosis

All of the following are directly associated, at least in part, with the lipid
components of the plasma membrane except
A
)
B
)
C
)
D
)

molecular bilayer framework


cholesterol molecules
catalytic enzymes
glycocalyx

A higher concentration of sodium ions in extracellular fluid versus cytosol is


most likely maintained by
A
)
B
)
C
)
D
)

blocking any passage of sodium through the plasma membrane


actively transporting sodium ions out of the cell
overcrowding the cytosol with potassium ions
none of the above

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Which of the following lists only non-membrane-bound organelles?


A
)
B
)
C
)
D
)

microvilli, ribosomes, centrioles, mitochondria, cytoskeleton


cytoskeleton, microvilli, centrioles, cilia, flagellum, ribosomes
microvilli, cytoskeleton, cilia, lysosomes, nucleus, ribosomes
cytoskeleton, endoplasmic reticulum, centrioles, nucleus, cilia, ribosomes

Which of the following lists only membrane-bound organelles?


A
)
B
)
C
)
D
)

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lysosomes, ribosomes, peroxisomes, endoplasmic reticulum, Golgi


apparatus
endoplasmic reticulum, Golgi apparatus, mitochondria, lysosomes,
peroxisomes
mitochondria, cilia, centrioles, Golgi apparatus, endoplasmic reticulum,
nucleus

Which one of the following organelles occurs in the fewest types of human
cells?
A
)
B
)
C
)
D
)

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microtubules, nucleus, lysosomes, ribosomes, mitochondria, cilia

nucleus
microtubule
flagellum
rough ER

Which of the following organelles are found in all living cells of the human
body?
A
)
B
)
C
)
D
)

nuclei
nucleoli
microvilli
microtubule

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The nucleus (and more specifically, the genes it contains) most directly
controls all of the cell's activities by
A
)
B
)
C
)
D
)

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regulating protein synthesis


synthesizing DNA and RNA
coordinating intracellular communication

Of the following, which organelle participates most directly in mitosis?


A
)
B
)
C
)
D
)

smooth endoplasmic reticulum


ribosome
centriole
nucleolus

Which series progresses from the thinnest to the thickest in diameter?


A
)
B
)
C
)
D
)

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controlling cell division

DNA > histone > chromosome > nucleosome


histone > chromosome > DNA > nucleosome
nucleosome > histone > DNA > chromosome
DNA > histone > nucleosome > chromosome

Although often described as somatic cell division, ____________ is actually


division of the nucleus.
A
)
B
)
C
)
D
)

meiosis
mitosis
cytokinesis
interphase

Mitosis plays a role in all of the following processes except

CT
A tissue growth and repair
)
B replacement of old or dying cells
)
C sex cell production
)
D embryo formation
)

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In an adult, which of the following usually have the longest G0 phase?


A
)
B
)
C
)
D
)

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blood cells
nerve cells
epithelial skin cells
the G0 phase is the same length in all of these

The longest part of a mature muscle cell's life cycle is


A
)
B
)
C
)
D
)

the G2 phase
the S phase
interphase
mitosis

During which stages of mitosis does a typical cell contain twice its normal
number of chromosomes? (1) prophase (2) metaphase (3) anaphase (4)
telophase
A 1 and 2
)
B 2 and 3
)
C 3 and 4
)
D all of the above
)

Which of the following organelles might function during or even after


apoptosis of the cell that contains them?

A
)
B
)
C
)
D
)

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Golgi apparatus
rough endoplasmic reticulum
lysosomes

Which property of cancer cells most directly contributes to metastasis?


A
)
B
)
C
)
D
)

invasiveness
dedifferentiation
production of angiogenesis factors
loss of contact inhibition

____________ is caused by a genetic defect in mitochondrial rather than


nuclear DNA.
A
)
B
)
C
)
D
)

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centrioles

cystic fibrosis
MELAS syndrome
adrenoleukodystrophy
Tay-Sachs disease

If organelles can proliferate in response to increased demand, then one could


expect to find far more ____________ in the liver cells of an alcoholic than in
a nondrinker.
A rough ER
)
B smooth ER
)
C mitochondria
)
D lysosomes
)

Which of the following cellular changes would generally be indicative of


cancer?
A anaplasia
)

B hyperplasia
)
C hypertrophy
)
D all of the above
)

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To destroy bacteria in the interstitial fluid, leukocytes would most likely


employ the process of
A
)
B
)
C
)
D
)

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receptor-mediated endocytosis
pinocytosis
bulk filtration
phagocytosis

When a cell begins to divide, its chromatin forms


A)

nucleoli.

B)

chromosomes.

C)

histones.

D)

none of these.

Which of the following describes integral membrane proteins?


A)

They only permit water movement into or out of the cell.

B)

They only transport large proteins into the cell.

C)

They extend across the phospholipid bilayer.

D)

They are attached to the external membrane surface.

Facilitated diffusion differs from active transport in that facilitated


diffusion
A)

expends no ATP.

B)
C)
D)

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moves molecules from an area of higher concentration to one of


lower concentration.
does not require a carrier protein for transport.
moves molecules in vesicles across a semipermeable
membrane.

Which plasma membrane structures serve in cell recognition and act as a


"personal ID card" for the cell?
A)

integral proteins and peripheral proteins

B)

glycolipids and glycoproteins

C)

phospholipids and cholesterol

D)

cholesterol and integral proteins

The __________ increase the outer surface area of the plasma


membrane to increase absorption.
A)

centrioles

B)

cilia

C)

microvilli

D)

flagella

The major functions of the Golgi apparatus are


A)

diffusion and osmosis.

B)

detoxification of substances and removal of waste products.

C)

synthesis of new proteins for the cytoplasm.

D)

packaging, sorting, and modification of new molecules.

Interphase of the cell cycle consists of the following parts:


A)

prophase, metaphase, anaphase, and telophase.

B)

G1, S, and G2.

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C)

mitosis and cytokinesis.

D)

all of these.

The organelle that provides most of the ATP needed by the cell is the
A)

endoplasmic reticulum.

B)

mitochondrion.

C)

lysosome.

D)

Golgi apparatus.

During which phase of mitosis do the sister chromatids begin to move


apart from each other at the middle of the cell?
A)

prophase

B)

metaphase

C)
anaphase
D)

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telophase

When a cell is not dividing, its DNA is in the form called


A)

chromatin.

B)

chromosomes.

C)

genes.

D)

nucleoli.

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