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Summary
Report
Patient 1 was a 48-year-old black woman, who
presented with a 3-year history of asymptomatic lesions
Correspondence: Dr John Moche, Johannesburg Hospital, Division of Dermatology, Area 553, No 7 York Road, Parktown, South Africa 2193
E-mail: moche@healthbridge.za.net
Conflict of interest: none declared.
Accepted for publication 30 September 2008
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(a)
(b)
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(b)
(c)
(d)
Figure 2 Patient 1. Biopsy from the face showing (a) prominent ochronotic fibres with solar elastosis and (b) multinucleated giant cells
with ochrophagocytosis. Biopsy from the neck showing (c) sarcoidal granulomas associated with calcified and degenerate ochronotic
fibres and (d) basophilia and swelling of collagen admixed with ochronotic fibres. Haematoxylin and eosin, original magnification (a) 20;
(b,c) 40.
(a)
(b)
Figure 3 Patient 2. (a) annular plaque on the face studded with milia-like papules and residualcosmetic ochronosis; (b) sarcoidal
granulomatous infiltrate associated with yellowish-brown ochronotic fibres (haematoxylin and eosin, original magnification 40).
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402
Acknowledgements
We thank E. Liebenberg, School of Pathology, University
of the Witwatersrand, for the microphotography.
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