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Title
Journal
Acodingindependentfunctionofgeneandpseudogene
Nature
mRNAsregulatestumourbiology
AChromatinMediatedReversibleDrugTolerantStatein
Cell
CancerCellSubpopulations
LongnoncodingRNAHOTAIRreprogramschromatinstate
Nature
topromotecancermetastasis
LeukemicIDH1andIDH2MutationsResultina
HypermethylationPhenotype,DisruptTET2Function,and CancerCell
ImpairHematopoieticDifferentiation
Tumourvascularizationviaendothelialdifferentiationof
Nature
glioblastomastemlikecells
Diversesomaticmutationpatternsandpathwayalterations
Nature
inhumancancers
KinaseDeadBRAFandOncogenicRASCooperatetoDrive
Cell
TumorProgressionthroughCRAF
RAFinhibitorsprimewildtypeRAFtoactivatetheMAPK
Nature
pathwayandenhancegrowth
Wntactivitydefinescoloncancerstemcellsandis
NatureCellBiology
regulatedbythemicroenvironment
Thetranscriptionalnetworkformesenchymal
Nature
transformationofbraintumours
MelanomasacquireresistancetoBRAF(V600E)inhibition
Nature
byRTKorNRASupregulation
COTdrivesresistancetoRAFinhibitionthroughMAPkinase
Nature
pathwayreactivation
AMycNetworkAccountsforSimilaritiesbetween
Cell
EmbryonicStemandCancerCellTranscriptionPrograms
RAFinhibitorstransactivateRAFdimersandERKsignalling
Nature
incellswithwildtypeBRAF
CoadministrationofaTumorPenetratingPeptide
Science
EnhancestheEfficacyofCancerDrugs
TheCommonFeatureofLeukemiaAssociatedIDH1and
IDH2MutationsIsaNeomorphicEnzymeActivity
CancerCell
ConvertingalphaKetoglutarateto2Hydroxyglutarate
Impairedhydroxylationof5methylcytosineinmyeloid
Nature
cancerswithmutantTET2
RNAiscreenidentifiesBrd4asatherapeutictargetinacute
Nature
myeloidleukaemia
BETBromodomainInhibitionasaTherapeuticStrategyto
Cell
TargetcMyc
BiomechanicalRemodelingoftheMicroenvironmentby
Cell
StromalCaveolin1FavorsTumorInvasionandMetastasis
Discoveryandpreclinicalvalidationofdrugindications
usingcompendiaofpublicgeneexpressiondata
Selectivekillingofcancercellsbyasmallmolecule
targetingthestressresponsetoROS
Functionalgenomicsrevealthattheserinesynthesis
pathwayisessentialinbreastcancer
CodingIndependentRegulationoftheTumorSuppressor
PTENbyCompetingEndogenousmRNAs
Oncometabolite2HydroxyglutarateIsaCompetitive
InhibitorofalphaKetoglutarateDependentDioxygenases

Authors

Year

DOI

PolisenoL.,SalmenaL.,ZhangJ.,Ca

2010 10.1038/nature09144

JSharmaS.V.,LeeD.Y.,LiB.,Quinla

2010 10.1016/j.cell.2010.02.027

GuptaR.A.,ShahN.,WangK.C.,Kim

2010 10.1038/nature08975

FigueroaM.E.,AbdelWahabO.,Lu

2010 10.1016/j.ccr.2010.11.015

RicciVitianiL.,PalliniR.,BiffoniM.,

2010 10.1038/nature09557

KanZ.,JaiswalB.S.,StinsonJ.,Janak

2010 10.1038/nature09208

HeidornS.J.,MilagreC.,Whittaker

2010 10.1016/j.cell.2009.12.040

HatzivassiliouG.,SongK.,YenI.,Br

2010 10.1038/nature08833

VermeulenL.,DeSousaEMeloF.,V

2010 10.1038/ncb2048

CarroM.S.,LimW.K.,AlvarezM.J.,

2010 10.1038/nature08712

NazarianR.,ShiH.,WangQ.,KongX

2010 10.1038/nature09626

JohannessenC.M.,BoehmJ.S.,Kim

2010 10.1038/nature09627

KimJ.,WooA.J.,ChuJ.,SnowJ.W.,

2010 10.1016/j.cell.2010.09.010

PoulikakosP.I.,ZhangC.,BollagG.,

2010 10.1038/nature08902

SugaharaK.N.,TeesaluT.,Prakash

2010 10.1126/science.1183057

WardP.S.,PatelJ.,WiseD.R.,Abde

2010 10.1016/j.ccr.2010.01.020

KoM.,HuangY.,JankowskaA.M.,P

2010 10.1038/nature09586

ZuberJ.,ShiJ.,WangE.,Rappaport

2011 10.1038/nature10334

DelmoreJ.E.,IssaG.C.,LemieuxM.

2011 10.1016/j.cell.2011.08.017

GoetzJ.G.,MinguetS.,NavarroLer

2011 10.1016/j.cell.2011.05.040

ScienceTranslationalMedicine SirotaM.,DudleyJ.T.,KimJ.,Chian

2011 10.1126/scitranslmed.3001318

Nature

RajL.,IdeT.,GurkarA.U.,FoleyM.,

2011 10.1038/nature10167

Nature

PossematoR.,MarksK.M.,ShaulY.

2011 10.1038/nature10350

Cell

TayY.,KatsL.,SalmenaL.,WeissD.

2011 10.1016/j.cell.2011.09.029

CancerCell

XuW.,YangH.,LiuY.,YangY.,Wan

2011 10.1016/j.ccr.2010.12.014

Crap?

Why?

crap

ceRNAsarebullshit

crap

lncRNAsarebullshit

crap

tumorstemcellsarebullshit

crap

ceRNAsarebullshit

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OncogeneinducedNrf2transcriptionpromotesROS
Nature
detoxificationandtumorigenesis
BRCA1tumoursuppressionoccursviaheterochromatin
Nature
mediatedsilencing
ThemicroRNAmiR34ainhibitsprostatecancerstemcells
NatureMedicine
andmetastasisbydirectlyrepressingCD44
InhibitionofBETrecruitmenttochromatinasaneffective
Nature
treatmentforMLLfusionleukaemia
CCL2recruitsinflammatorymonocytestofacilitatebreast
Nature
tumourmetastasis
AnExtensiveMicroRNAMediatedNetworkofRNARNA
InteractionsRegulatesEstablishedOncogenicPathwaysin Cell
Glioblastoma
Normalandneoplasticnonstemcellscanspontaneously
PNAS
converttoastemlikestate
Anendogenoustumourpromotingligandofthehuman
Nature
arylhydrocarbonreceptor
Senescencesurveillanceofpremalignanthepatocytes
Nature
limitslivercancerdevelopment
Arestrictedcellpopulationpropagatesglioblastoma
Nature
growthafterchemotherapy
Definingthemodeoftumourgrowthbyclonalanalysis
Nature
Systematicidentificationofgenomicmarkersofdrug
Nature
sensitivityincancercells
LineageTracingRevealsLgr5(+)StemCellActivityinMouse
Science
IntestinalAdenomas
TheCD47signalregulatoryproteinalpha(SIRPa)
PNAS
interactionisatherapeutictargetforhumansolidtumors
TumourmicroenvironmentelicitsinnateresistancetoRAF
Nature
inhibitorsthroughHGFsecretion
IntestinalInflammationTargetsCancerInducingActivityof
Science
theMicrobiota
Melanomaexosomeseducatebonemarrowprogenitor
NatureMedicine
cellstowardaprometastaticphenotypethroughMET
Interactionsbetweencancerstemcellsandtheirniche
Nature
governmetastaticcolonization
MelanomagenomesequencingrevealsfrequentPREX2
Nature
mutations
UnresponsivenessofcoloncancertoBRAF(V600E)
Nature
inhibitionthroughfeedbackactivationofEGFR
Widespreadpotentialforgrowthfactordrivenresistance
Nature
toanticancerkinaseinhibitors
IDHmutationimpairshistonedemethylationandresultsin
Nature
ablocktocelldifferentiation
TranscriptionalAmplificationinTumorCellswithElevatedc
Cell
Myc
SequentialApplicationofAnticancerDrugsEnhancesCell
Cell
DeathbyRewiringApoptoticSignalingNetworks
Fusobacteriumnucleatuminfectionisprevalentinhuman
GenomeResearch
colorectalcarcinoma
DNAbreaksandchromosomepulverizationfromerrorsin
Nature
mitosis
AmicroRNAregulonthatmediatesendothelialrecruitment
Nature
andmetastasisbycancercells

DeNicolaG.M.,KarrethF.A.,Humpt

2011 10.1038/nature10189

ZhuQ.,PaoG.M.,HuynhA.M.,Suh

2011 10.1038/nature10371

LiuC.,KelnarK.,LiuB.,ChenX.,Cal

2011 10.1038/nm.2284

DawsonM.A.,PrinjhaR.K.,Dittman

2011 10.1038/nature10509

QianB.Z.,LiJ.,ZhangH.,Kitamura

2011 10.1038/nature10138

SumazinP.,YangX.,ChiuH.S.,Chu

2011 10.1016/j.cell.2011.09.041

ChafferC.L.,BrueckmannI.,Scheel

2011 10.1073/pnas.1102454108

OpitzC.A.,LitzenburgerU.M.,Sahm

2011 10.1038/nature10491

KangT.W.,YevsaT.,WollerN.,Hoe

2011 10.1038/nature10599

ChenJ.,LiY.,YuT.S.,McKayR.M.,

2012 10.1038/nature11287

DriessensG.,BeckB.,CaauweA.,S

2012 10.1038/nature11344

GarnettM.J.,EdelmanE.J.,Heidorn

2012 10.1038/nature11005

SchepersA.G.,SnippertH.J.,Stange

2012 10.1126/science.1224676

WillinghamS.B.,VolkmerJ.P.,Gen

2012 10.1073/pnas.1121623109

StraussmanR.,MorikawaT.,SheeK

2012 10.1038/nature11183

ArthurJ.C.,PerezChanonaE.,Muh

2012 10.1126/science.1224820

PeinadoH.,AleckovicM.,Lavotshki

2012 10.1038/nm.2753

MalanchiI.,SantamariaMartinezA

2012 10.1038/nature10694

BergerM.F.,HodisE.,HeffernanT.P

2012 10.1038/nature11071

PrahalladA.,SunC.,HuangS.,DiNi

2012 10.1038/nature10868

WilsonT.R.,FridlyandJ.,YanY.,Pen

2012 10.1038/nature11249

LuC.,WardP.S.,KapoorG.S.,Rohle

2012 10.1038/nature10860

LinC.Y.,LovenJ.,RahlP.B.,Paranal

2012 10.1016/j.cell.2012.08.026

LeeM.J.,YeA.S.,GardinoA.K.,Heij

2012 10.1016/j.cell.2012.03.031

CastellarinM.,WarrenR.L.,Freema

2012 10.1101/gr.126516.111

CrastaK.,GanemN.J.,DagherR.,La

2012 10.1038/nature10802

PngK.J.,HalberN.,YoshidaM.,Tav

2012 10.1038/nature10661

crap

miRNAsarebullshit

crap

miRNAsarebullshit

52

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ReductiveglutaminemetabolismbyIDH1mediates
lipogenesisunderhypoxia

Nature

MetalloC.M.,GameiroP.A.,BellE.L

2012 10.1038/nature10602