Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Itraconazole
Page: 1
Revision: 06/13/2012
13288
Product Name:
Itraconazole
Synonyms:
4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]p
henyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one;
Intended Use:
Manufacturer Information
Company Name:
Emergency Contact:
+1 (800)424-9300
+1 (703)527-3887
Information:
www.caymanchem.com
+1 (734)971-3335
2. Hazards Identification
GHS Classification
Acute Toxicity: Oral, Category 4
Placard
Exclamation
Key word
GHS Hazard
Warning
Harmful if swallowed
Warning
Warning
Warning
point
Skin Corrosion/Irritation, Category 2
Exclamation
point
Exclamation
2A
point
Exclamation
exposure), Category 3
point
and dizziness
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Multi-region format
Inhalation? Yes
Skin? Yes
Eyes? Yes
Page: 2
Revision: 06/13/2012
Ingestion? Yes
Other: Injection
Potential Health Effects (Acute and Chronic): Causes skin and serious eye irritation.
Harmful if swallowed.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation or skin absorption.
May cause respiratory system irritation.
Target Organs:
Heart, Liver.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
3. Composition/Information on Ingredients
Hazardous Components (Chemical Name)
1.
Itraconazole
CAS #
84625-61-6
Concentration
EC#
Risk Phrases
100.0 %
617-596-9
R22-36/37/38
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
Immediately wash skin with soap and plenty of water for at least 20 minutes. Remove
contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
Hold eyelids apart and flush eyes with plenty of water for at least 20 minutes. Have eyes
examined and tested by medical personnel.
In Case of Ingestion:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
No data available.
No data available.
Flash Pt:
No data.
Autoignition Pt:
No data available.
Explosive Limits:
LEL: No data.
UEL: No data.
Environmental Precautions:
Released Or Spilled:
Multi-region format
Page: 3
Revision: 06/13/2012
Itraconazole
Itraconazole
CAS #
84625-61-6
CAS #
84625-61-6
OSHA PEL
ACGIH TLV
Other Limits
No data.
No data.
No data.
Britain EH40
France VL
No data.
No data.
Lab coat
Safety
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Eye Protection:
Safety glasses
Protective Gloves:
Lab coat
Work/Hygienic/Maintenance Practices:
[ ] Gas
A crystalline solid
Boiling Point:
No data.
Melting Point:
No data.
Autoignition Pt:
No data.
Flash Pt:
No data.
No data.
No data.
No data.
Evaporation Rate:
No data.
Solubility in Water:
No data.
Solubility Notes:
[ ] Liquid
[ X ] Solid
Other Information
Percent Volatile:
No data.
Formula:
C35H38Cl2N8O4
Molecular Weight:
705.60
Multi-region format
Page: 4
Revision: 06/13/2012
Unstable [
Stability Note(s):
Conditions To Avoid:
No data available.
Polymerization:
Will occur [
carbon dioxide
carbon monoxide
hydrogen chloride gas
nitrogen oxides
Stable [ X ]
The toxicological effects of this product have not been thoroughly studied.
No data available.
CAS #
Itraconazole
84625-61-6
NTP
IARC
ACGIH
OSHA
n.a.
n.a.
n.a.
n.a.
Xn: Harmful
Multi-region format
Itraconazole
CAS #
84625-61-6
Page: 5
Revision: 06/13/2012
Sec.302 (EHS)
Sec.304 RQ
Sec.313 (TRI)
Sec.110
No
No
No
No
CAA HAP,ODC
CWA NPDES
TSCA
CA PROP.65
No
No
No
No
Itraconazole
CAS #
84625-61-6
This SDS was prepared in accordance with 29 CFR 1910.1200, Regulation (EC) No.1272/2008,
and European Directive 67/548/EEC as amended.
Multi-region format