PREDISPOSING FACTORS:

Family History
Female
Middle age

PRECIPITATING FACTORS:
Diet
Obesity
Rapid weight loss
Use of oral contraceptives
Gallbladder, pancreatic or ileal disease
Low HDL cholesterol level
Hypertriglyceridemia
MRI RESULTS:
1. Dilated cystic side branches in direct
communication with pancreatic duct in the
region of uncinate process for which an IPMT
should be excluded

2. Multiple gallstones
3. Left renal cysts with wall calcifications
4. Tiny right renal corticocysts
5. Ascending and descending diverticula
CHOLELITHIASIS
Gallstones in the Bile duct

Increased Bile Cholesterol

Precipitate out of the bile

Irritation of Gallbladder
mucosa
Forms small crystals into
Gallbladders mucosal surface

Surface Changes
Enlarges to grossly visible stones
Increased Mucus Secretion
Several stones develop
Impaired Gallbladder
emptying

Obstruction

Distension

Bile Stasis

Contractile
function

Intraductal
Pressure

Biliary
Colic

RUQ
Pain

Injury

Bile
accumulates
in Liver

Jaundice

Biliary
Cirrhosis

Increase
Serum
Bilirubin

Abnormal
Fat
Digestion

Prorates/Tea
-collared
Urine

Anorexia
Nausea
Vomiting
Weight loss
Flatulence
Diarrhea
Fat
intolerance

Inflammation of
Gallbladder
Cholecystitis

Inflammat
Gallblad