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Higher National Diploma in Biomedical Science

Batch 2 & 3

Part 1 [LO: 3 & 4]

Re-sit

Qualification Higher National Diploma in Biomedical Science
Level 5
Module Name
Human Physiology
Module Number 04
Module Tutors Dr. Deepthi De Silva MBChB, MRCP(UK)
Dr. Minerva A De Silva MBBS, M Phil (Peradeniya)
Dr. W A D Lakmali Amarasiri MBBS, PhD (Kelaniya)
Time Allowed 2 hours (9.00am to 11:00am)
Exam Date 26
th
February 2013



Summary of Learning Outcomes


Part 1 consists of two questions of one hour each, which is clinically oriented and integrated.
These two questions are related to learning outcomes (3) and (4).


(3) Describe the components of homeostatic control systems.

(4) Discuss the coordination of organ systems in the maintenance of a constant internal
environment.







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Part 1 - (Answer BOTH questions)

Question 1

A 50 year old man complaining of a pain radiating down his left arm was diagnosed with a
myocardial infarction (heart attack). His blood pressure was 90/50 mmHg and pulse rate was
35/min.

a. Explain the reason for a heart attack causing pain radiating down his left arm. [30 marks]

b. State the normal blood pressure in an adult and comment on this patients blood pressure.
[15 marks]

c. Comment on this patients pulse rate. [10 marks]

d. Outline the pathway for excitation of the heart (transmission of the cardiac impulse).
[15 marks]

e. State the relationship between, pulse rate, cardiac output and blood pressure. [20 marks]

f. Explain the reason for this patients blood pressure. [10 marks]

[Total marks 100]


Question 2

The following is an arterial blood gas report of a 24 year old female who presented with difficulty
in breathing. Her respiratory rate was found to be 38/min.

pH : 7.31 (7.36 7.4)
PaO
2
: 58 mmHg (97 100 mmHg)
PaCO
2
: 48 mmHg (40 46 mmHg)
HCO
3
-
: 24 meq/L (22 26 meq/L)


a. Comment on her pH, PaCO
2
, PaO
2
and HCO
3
-
levels.

[5 x 4 marks=20 marks]

b. State the acid base imbalance in her. [10 marks]

c. State the 3 compensatory mechanisms likely to be activated in her. [15 marks]

d. List 3 buffers found in plasma and explain their importance. [15 marks]

e. List 3 buffers present in the kidney and explain their importance. [15 marks]

f. Explain the reason for her respiratory rate. [25 marks]

[Total marks 100]

~ End of Paper ~

BMS
Printed on: 2/23/2013 3:32:13 PM
BIO HP P 1| Feb 13 [B 2,3] RS