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DIGESTION
A Test
Answer Qs 1 to 4 by drawing a circle around
the best answer.
Answer the remaining questions in the spaces
provided.
Question 10 is for HL only.
Total marks: HL
46
SL
36
John Osborne
October 2014
1.
Which of the following is correct regarding the enzymes listed in the table?
Enzyme
Amylase
Lipase
Protease
A.
Substrate polysaccharide
emulsified fat
dipeptide or polypeptide
B.
dipeptide or polypeptide
polysaccharide
C.
Product
amino acids
small polysaccharides or
monosaccharides
D.
Product
2.
Lactose
B.
Sucrose
C.
Galactose
D.
Maltose
(Total 1 mark)
3.
In the digestive system, enzyme A has an optimum pH of 1.5 and enzyme B an optimum
pH of 7.
What are the possible substrates of these enzymes?
Enzyme A
Enzyme B
A.
proteins
amino acids
B.
lipids
proteins
C.
carbohydrates
lipids
D.
proteins
lipids
(Total 1 mark)
4.
Two cellular activities that support human life are absorption and assimilation. What is needed
for assimilation but not for absorption?
A.
B.
Blood capillaries
C.
Dissolved nutrients
D.
Microvilli
(Total 1 mark)
5.
[Source: P H Raven and G B Johnson, Biology, (2002), 6th edition, McGraw-Hill, page 1024]
(a)
(i)
1:
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2:
............................................................................................................................
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(2)
(ii)
6.
7.
State one other constituent of human diets that can be used as a respiratory
substrate.
...........................................................................................................................
(1)
(ii)
Outline two uses of carbohydrates in the human body, other than as a respiratory
substrate.
1. ......................................................................................................................
...........................................................................................................................
2. .......................................................................................................................
...........................................................................................................................
(2)
(b)
Monosaccharides are useful if energy is needed rapidly, but polysaccharides are a better
form of carbohydrate if energy is needed over a longer period.
(i)
1. ........................................................
2. ......................................................
(1)
(ii)
1. ........................................................
2. ......................................................
(1)
(Total 5 marks)
8.
(a)
Describe how the ileum uses active transport in the absorption of food.
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(3)
(b)
List two substances resulting from the breakdown of haemoglobin in the liver.
.....................................................................................................................................
(1)
(Total 4 marks)
9.
Researchers extracted an enzyme from the human digestive system and tested its
activity at
results are shown in the
Enzyme activity
1 2 3 4 pH
a) Deduce from where in the human digestive system this enzyme was extracted.
[1]
.....................................................................................................................................................
b) Outline the need for enzymes in the digestive system.
[2]
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c) State one function of the large intestine.
[1]
.....................................................................................................................................................
d) Explain how the structure of the villus is adapted for absorption.
[3]
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.. .....
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............................................................................................................................................................ .....
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(4)
(Total 7 marks)
10.
HL
Enzymes are used by living organisms to catalyse reactions. Some of these reactions occur in
the cytoplasm of cells. Other reactions take place outside cells, for example the digestion of
foods in the human gut.
(a)
State the name used by biochemists for the chains and cycles of reactions that occur
inside cells.
.....................................................................................................................................
(1)
(b)
Enzymes of digestion in humans are secreted by glands. They have a pH optimum
which allows them to work efficiently in the part of the gut into which they are secreted.
(i)
In the table below, identify the missing enzyme, the two glands, and the pH
optimum
Name of
enzyme
amylase
Gland secreting
the enzyme
Substrate
Products
starch
maltose
triglycerides
pH optimum
7
(4)
(ii)
Outline the effect of pH values above and below the optimum on enzyme structure.
.....................................................................................................................................
.....................................................................................................................................
.....................................................................................................................................
.....................................................................................................................................
.....................................................................................................................................
(2)
(c)
Enzymes that work inside cells are sometimes affected by non-competitive inhibitors.
Explain how a non-competitive inhibitor affects the activity of an enzyme.
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(3)
(Total 10 marks)
11.
Osteoporosis is a major health problem for many post-menopausal women. As the
ovaries reduce their secretion of estrogen, calcium is gradually lost from bones, weakening them
and increasing the chance of fractures. To test whether diet influences the rate of calcium loss,
ovaries were removed from groups of female rats and the rats were then either fed a control diet or
the same diet with one gram of a supplementary food per day. The rate at which the rats excreted
calcium was measured. The ratio of calcium loss between the control rats and the rats that were
Ratio
0 .6
0 .4
0 .2
0 .0
S u p p le m e n ta ry fo o d
[Source: Muhlbauer and Li, Nature, 1999, 401, pages 343344]
(a)
(i)
Identify which supplementary food was most effective in reducing calcium loss.
...........................................................................................................................
(1)
(ii)
Identify which supplementary food was least effective in reducing calcium loss.
...........................................................................................................................
(1)
(b)
Among the ten foods shown in the graph, seven are plant products (vegetables) and three
are animal products. Discuss whether the plant or the animal products were more
effective at reducing calcium loss.
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.....................................................................................................................................
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(3)
10
(c)
Suggest a trial, based on the results shown in the graph, that could be done to try to
reduce osteoporosis in humans.
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(3)
(Total 8 marks)
11