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ORODISPERSIBLE TABLETS
M.PHARM DISSERTATION PROTOCOL
SUBMITTED TO
2.
KARNATAKA COLLEGE OF
PHARMACY
# 33/2 Thirumenahalli
Hegde Nagar Main Road
Bengaluru - 560064
Karnataka.
3.
MASTER OF PHARMACY IN
PHARMACEUTICAL
TECHNOLOGY
4.
5.
Title of Topic:
6.
6.1
quick onset of action. Some drugs are absorbed from mouth, pharynx and oesophagus as
the saliva passes down into the stomach. In such cases, bioavailability of drug is
significantly greater than those observed from conventional tablet dosage form.
Orodispersible tablets are prepared by various techniques; mainly direct compression,
wet granulation, sublimation, lyophilisation and moulding. The simplicity and cost
effectiveness of the direct compression process have positioned this technique as an
attractive alternate to traditional granulation technologies.
There is therefore a need for dosage forms which have all the advantages of a tablet
formulation and the bioavailability and convenience of administration of a suspension. A
disintegrating tablet is one such dosage form which meets the needs. They are easy to
carry and can be reconstituted and administered to patients accurately and conveniently.
The oral tablet of antihypertensive drugs can improve symptoms and quality of patients
with respective to pediatric patients. The physical problems with swallowing (dysphagia)
can exacerbate compliance problems and undermine treatment efficacy.
The data was obtained from the literature survey and Internet source.
7.4 Has the Ethical Clearance been obtained from your Institution in case of 7.3 ?
NOT APPLICABLE
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polymers: In vitro and in vivo evaluation. Eur J Pharm Biopharm. 2011 Feb:in
press.
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11.3 Co-Guide
( DR. K.RAMESH )