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PEPTIC ULCER
DISEASE
DISEASE
PEPTIC ULCER
PEPTIC ULCER
DISEASE
DISEASE
Introduction
Peptic Ulcer
Ulcers average between one-uarter and one-!al" inc! in
dia#eter$ T!e% develop w!en digestive &uices produced in
t!e sto#ac!' intestines' and digestive glands da#age t!e
lining o" t!e sto#ac! or duodenu#$
T!e two i#portant digestive &uices are !%droc!loric acid and
t!e en(%#e pepsin$ )ot! substances are critical in t!e
brea*down and digestion o" starc!' "at' and proteins in
"ood$ T!e% pla% di""erent roles in ulcer+
,%droc!loric Acid$ A co##on #isbelieve is t!at e-cess
!%droc!loric acid' w!ic! is secreted in t!e sto#ac!' is
solel% responsible "or producing ulcers$
,$ p%lori- t!e bacteria t!at !as been t!e cause o"
#ost peptic ulcers$
Pepsin$ Is an en(%#e t!at brea*s down proteins in
"ood$ Since t!e sto#ac! and duodenu# are also
co#posed o" protein' !owever' t!e% too are
susceptible to t!e actions o" pepsin$
)icarbonate' w!ic! t!e #ucous la%er secretes'
neutrali(es t!e digestive acids$ ,or#one li*e
substances called prostaglandins !elp *eep t!e blood
vessels in t!e sto#ac! dilated' ensuring good blood
"low and protecting against in&ur%$
.Prostaglandins are also believed to sti#ulate
bicarbonate and #ucus production$
Patient Pro"ile
Age+ 23 %$o$
Status+ 4arried
5ccupation+ !ousewi"e
Citi(ens!ip+ 1ilipino
Digestive s%ste# is t!e series o" tube-li*e organ t!at converts our #eals
into c!e#ical co#pound t!at can be absorbed b% t!e bod%/s cells$ It also
separates out unneeded #aterials and "lus!ed t!e# out o" t!e bod%$ In all
t!ere/s about 3;-"oot-long.=-#eter-longI tube t!at begins wit! t!e #out!'
w!ere "ood enters t!e bod%' and ends wit! t!e anus' w!ere solid wastes
are e-pelled$ Along t!e wa%' "ood is bro*en down' sorted' and reprocessed
be"ore being circulated around t!e bod% to nouris! and replace cells and
suppl% energ% to our #uscles$
Mout, & T,roat
T!e digestive process begins !ere' w!ere "ood is grind into pieces and
prepared "or deliver% to t!e sto#ac!$ It t!en enters t!e p!ar%n-' or
t!roat a #uscular "unnel t!at pus!es t!at c!ewed "ood into t!e esop!agus
w!ile si#ultaneousl% bloc*ing o"" t!e trac!ea. @ind pipeI$
Salivar# Glan"s* T!ree pairs o" salivar% glands secrete saliva' a #i-ture o"
water' en(%#es and glue% protein called 4ucin' into t!e #out! to #oisten
t!e "ood$ En(%#es in t!e saliva interact wit! "ood and begin t!e process o"
c!e#ical digestion$
Teet,* )on% structures t!at tear' c!op' and grind "ood "or swallowing$
S!arp incisors and pointed canines in t!e "ront o" t!e #out! are designed
to tear into toug! "oods' w!ile "lattened pre#olars and #olars in t!e bac*
grind grains and plant #atter$
Ton!ue- T!is #uscular organ #aneuvers "ood around during c!ewing and
#i-es it wit! saliva to "or# a wet lu#p called a )5LUS$ T!e top and sides
o" t!e tongue are covered wit! little pro&ection called papillae' #an% o"
w!ic! contains taste buds$
Esop,a!us* T!e esop!agus is <;-inc!-long.:9-c#-longI #uscular tube t!at
connects t!e p!ar%n- to t!e sto#ac! $ @!en "ood enters t!e esop!agus' a
wave o" #uscular contractions called PERISTALSIS pus! and pull t!e "ood
to t!e sto#ac!$ 4ucus secretion *eep t!e lu#p o" "ood' or bolus sliding a
#ere "our to eig!t seconds$
Upper Esopa,a!eal Sp,incter* T!is valve' "ound &ust below t!e
intersection o" t!e t!roat and esop!agus' is a ring o" #uscles t!at rela-es
to let "ood enter t!e esop!agus$
Stomac,* t!is #uscular' e-pandable 8-s!aped pouc! is responsible "or
!olding and digesting "ood' as well as re#oving it/s nutrients$ @!en "ood
enters t!e sto#ac!' its #uscular walls contact and c!urn t!e "ood wit!
power"ul gastric acids t!at *ill bacteria and brea* down proteins$ T!e
result is a crea#% substance called C,C4E w!ic! t!e sto#ac! stores until
it is read% "or release into t!e s#all intestine$
0iver- weig!ing in at 3 pounds.<$3HgI' t!is wedge-s!aped organ is t!e bod%/s
largest gland$ T!e liver is an accessor% organ "or t!e digestive s%ste#$
A#ong its #an% roles is deto-i"ication o" t!e blood$ It also creates bile'
w!ic! is used to brea* down "ats$
Gall 1la""er* t!is plu#-si(e' green' #uscular sac !angs "ro# t!e liver$ T!e
gall bladder collects' stores' and concentrate bile "ro# t!e liver$
Pancreas- T!is long organ' positioned be!ind t!e sto#ac!' produces insulin
and en(%#es t!at aid digestion$ Pancreatic en(%#es !elp digest "ood in t!e
s#all intestine' w!ile insulin !elps regulate t!e a#ount o" sugar in t!e
blood$
Intestines* T!e s#all intestine #easures :; "eet.G#etersI in lengt! and <
inc!.:$9c#I in dia#eter$ T!ousands o" "olds and #illions o" "inger-li*e
pro&ection called 6ILL increase t!e sur"ace are o" t!e s#all intestine
'w!ic! absorb =;J o" nutrients and water t!e bod% will receive "ro#
digested "ood$
uo"enum* T!is is t!e "irst portion o" t!e s#all intestine' w!ere secretion
"ro# t!e liver and pancreas are received and #ost o" t!e c!e#ical
digestion ta*es place$
2e3unum* T!is is t!e long' coiled #iddle portion o" t!e s#all intestine t!at
stretc!es "ro# t!e duodenu# to t!e ileu#$
Ileum* t!is is t!e "inal portion o" t!e s#all intestine' w!ere re#aining
nutrients are absorbed and utili(ed$
T!e Large Intestine absorb t!e last bits o" nutrients and water "ro#
indigestible "oods' co#pacts t!e re#aining #atter' and eli#inates it as
"eces$
Ascen"in! (olon* t!e large intestine surrounds t!e s#all intestine li*e an
inverted C$ T!e "irst portion o" t!e large intestine' t!e ascending colon' is
sti#ulated verticall% on t!e rig!t side o" t!e bod%$ T!e ascending colon
e-tracts re#aining #oisture "ro# "ood be"ore its e-cretion$
Transverse (olon* Connecting t!e ascending and descending colons' t!is
part o" t!e large intestine is situated !ori(ontall% above t!e s#all
intestine$
escen"in! (olon* 1ound on t!e le"t side o" t!e bod%' t!e descending'
or le"t colon' stores stool t!e will be e#ptied into t!e rectu#
Rectum* 5nl% 9 inc!es.<:c#I long' t!e rectu# sits &ust above t!e anal
canal$ 1eces are stored !ere brie"l% prior to de"ecation$
Anus* T!is ring o" #uscles is t!e e-ternal opening o" t!e rectu#'
t!roug! w!ic! "ecal #atter is e-pelled$ Peristaltic waves in t!e colon
and contraction o" t!e abdo#inal #uscles trigger de"ecation$
PATH)PH/SI)0)G/
Damage to mucosa with
alcohol abuse, smoking, use
of NSAIDs
Infection with Helicobacter
Pylori
Damaged mucousal
Erosion of mucous
membrane
ow function of mucosal
cells! low "uality of
mucous
Erosi#e gastritis
Se#ere ulcerations$
Signs and symptoms:
%E&igastric &ain
%Hematemesis
%&ale
%&yrosis
'ucosal ulcerations
DIAA05STIC TEST
Aastroscop%
Endoscop%
Sto#ac! biops%
A0TI)I5TICS
-#etrodina(ole ' a#o-icillin '
clarit!ro#%cin
-to eradicate !$p%lori
-surgical intervention
)is#ut! salts
-suppress or eradicate !$p%lori
Dietar% #odi"ication
Surgical procedure
-vagoto#%
-)illrot! I and )illrot! II
4a!otom#
-A va!otom# is a surgical
procedure t!at is per"or#ed onl%
in !u#ans$ It is resection
.re#oval o"' or at least severingI
o" part o" t!e vagus nerve$
Antrecto#% .billrot! II
- is t!e resection' or surgical
re#oval' o" a part o" t!e sto#ac!
*nown as t!e antru#$ T!e antru# is
t!e lower t!ird o" t!e sto#ac! t!at
lies between t!e bod% o" t!e sto#ac!
and t!e p%loric canal' w!ic! e#pties
into t!e "irst part o" t!e
s#all intestine$
15LL5@ UP C,ECH UP
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4onitor I F 5
Stress relie"
E-ercises
Li"est%le c!anges
0o to spices F peppers