AP Biology Pedigree Problem Set

NOTE: Some genotypes cannot be determined in these problems- write ALL possible for those.
1. Jim and Jill are both tonge-rollers !TT or Tt " yo determine which#. They ha$e %
children. The children are shown in the pedigree below. &rite in the genotype for all
indi$idals on the pedigree. NOTE: 'n this pedigree( the indi$idals are only shown as
ha$ing the trait- it is p to yo to determine if they are homo)ygos or hetero)ygos-
half-shaded bo*es are NOT being sed for this e*ample.
2. Adriana and Ja$ier ha$e + children. Adriana has type A, blood and Ja$ier has type ,
blood. List the missing genotypes for the pedigree shown below. -'NT: &or. from
bottom to top.
'
A
'
,
'
,
'
,
'
,
i
,lood /enotypes
A 0 '
A
'
A
( '
A
i
, 0 '
,
'
,
( '
,
i
A, 0 '
A
'
,
1 0 ii
3. 2se the information yo ha$e learned abot pedigrees to constrct a pedigree for the
following family. 2se E for earlobe attachment. Shade the whole symbol for dominant
traits and half of the symbol for hetero)ygos traits. Unattached earlobes are
dominant to attached.
a. 3ather 0 hetero)ygos for nattached earlobes.
b. 4other 0 homo)ygos recessi$e for attached earlobes.
c. 4ale 5hild 6 0 hetero)ygos
d. 4ale 5hild 7 0 homo)ygos recessi$e
e. 3emale 5hild 0 hetero)ygos
4. 5onstrct a pedigree for the following family. 8o may ha$e to wor. bac.wards on some
of the indi$idals. 3ill in the missing phenotypes for indi$idals in the list below. 8o
ha$e been gi$en enogh cles to fill the genotypes !remember- if yo cannot determine
if they are homo)ygos dominant or hetero)ygos( then write both#.
a. 2se a rler to ma.e the diagram neat. Shade the whole symbol for dominant
indi$idals and shade half of the symbol for hetero)ygos indi$idals and there is
no shading for recessi$e. 2se the bac. or another sheet of paper if yo need more
room.
b. Dimples (D) are dominant oer no dimples.
c. John 0 9imples
d. 4ary 0 9imples
e. L.e !child of John and 4ary# 0 9imples !homo)ygos#
f. Sarah !child of John and 4ary# 0 No 9imples
g. 4ar. !child of John and 4ary# 0 9imples
h. Eli)abeth !wife of L.e# 0 No 9imples
i. Johnny !child of L.e and Eli)abeth# 0 : ;;;;;;;;;;;;;;;;;;;;;
<. 4atthew !child of L.e and Eli)abeth# 0 : ;;;;;;;;;;;;;;;;;;;;
.. Ann !child of L.e and Eli)abeth# 0 : ;;;;;;;;;;;;;;;;;;;;;;;;
l. 4argaret !wife of 4ar.# 0 9imples
m. =atherine !child of 4argaret and 4ar.# 0 hetero)ygos dimples
n. /race !child of 4argaret and 4ar.# 0 homo)ygos dimples
o. 5laire !child of 4argaret and 4ar.# 0 9imples
p. 4ichael !hsband of 5laire# 0 No 9imples
>. 5aroline !child of 5laire and 4ichael# 0 -etero)ygos 9imples
!. A man and woman marry. They ha$e fi$e children( 7 girls and + boys. The mother is a
carrier of hemophilia( an ?-lin.ed disorder. She passes the gene on to two of the boys
who died in childhood and one of the daghters is also a carrier. ,oth daghters marry
men withot hemophilia and ha$e + children !7 boys and a girl#. The carrier daghter
has one son with hemophilia. One of the non-carrier daghter@s sons marries a woman
who is a carrier and they ha$e twin daghters. 5onstrct a pedigree to show the
inheritance pattern of this family. "hat is the percent chance that each
da#ghter $ill also be a carrier%
Type
A
&. The great-great maternal grandmother of a boy was a carrier for color-blindness( an ?-
lin.ed disorder. -is great ncle on his mother@s side was colorblind bt this great
ncle@s father was naffected. The boy@s mother has 7 brothers !6 colorblind( 6
naffected# and 6 sister !naffected#. The boy@s grandmother on his mother@s side had 6
brother who was colorblind and + sisters. Two of these sisters were naffected and one
was a carrier. The boy@s great grandmother on his mother@s side had % sisters. The boy
has one naffected sister and he is colorblind. 5onstrct a pedigree to show the
inheritance pattern of this family. "hat is the probability o' the boy(s sons being
colorblind i' he marries a non)carrier%
*. An naffected man marries a woman who is a carrier for 9chenne 4sclar
9ystrophy( which is attribted to an ?-lin.ed gene. They ha$e for children( one with
9chenne( one carrier daghter and a daghter and son who are naffected. The child
with 9chenne 4sclar 9ystrophy dies in childhood. The carrier daghter marries
and has three children of her own( two of which are carriers and one of which is
naffected. 5onstrct a pedigree to show the inheritance pattern of this family. "hat
is the most li+ely se, o' these t$o carrier children gien the 'act that they
are #na''ected by the -)lin+ed gene%
?
-
0 normal
?
h
0 hemophilia !a genetic disease or abnormality#
8 0 8 chromosome !males only#
?
5
0 normal
?
c
0 5olorblind !a genetic disease or abnormality#
8 0 8 chromosome !males only#
?
9
0 normal
?
d
0 9chenne 49 !a genetic disease or abnormality#
8 0 8 chromosome !males only#
Bonus Problem:
Use the $ords to this song to dra$ a pedigree.
./m 0y 1$n 2randpa
!Lon)o A Oscar #
't sonds fnny( ' .now(
,t it really is so(
Oh( 'Bm my own grandpa.
'Bm my own grandpa.
'Bm my own grandpa.
't sonds fnny( ' .now(
,t it really is so(
Oh( 'Bm my own grandpa.
Now many( many years ago( when ' was twenty-three(
' was married to a widow who was pretty as cold be.
This widow had a grown-p daghter who had hair of red.
4y father fell in lo$e with her( and soon they( too( were wed.
This made my dad my son-in-law and changed my $ery life(
4y daghter was my mother( case she was my fatherBs wife.
To complicate the matter( e$en thogh it broght me <oy(
' soon became the father of a boncing baby boy.
4y little baby then became a brother-in-law to 9ad(
And so became my ncle( thogh it made me $ery sad.
3or if he was my ncle( then that also made him brother
Of the widowBs grown-p daghter( who( of corse( was my stepmother.
3atherBs wife then had a son who .ept him on the rn(
And he became my grandchild( for he was my daghterBs son.
4y wife is now my motherBs mother( and it ma.es me ble(
,ecase( althogh she is my wife( sheBs my grandmother( too.
Now if my wife is my grandmother( then 'Bm her grandchild(
And e$erytime ' thin. of it( it nearly dri$es me wild(
3or now ' ha$e become the strangest case yo e$er saw
As hsband of my grandmother( ' am my own grandpaC
'Bm my own grandpa.
'Bm my own grandpa.
't sonds fnny( ' .now( bt it really is so(
Oh( 'Bm my own grandpa.