HEMATOLOGY

1. Branch of science concerned with the study

of blood, blood-forming tissues and
disorders associated with them
2. Connective tissue composed of a liquid
extracellular matrix that dissolves and
suspends various cells and cell fragments.
3. Liquid extracellular matrix of the blood
4. Color when it has high O
2
? Low O
2
?
5. Withdrawal of blood from a vein using a
needle and collecting tube?
6. Give one common site for venipuncture?
7. Procedure wherein blood is withdrawn from
an artery; used to determine the level of
oxygen in oxygenated blood
8. WBCs are ____ dense than RBCs but ____
than blood plasma, hence, they form a very
thin ____ .
9. Most of the plasma proteins are synthesized
by?
10. Plasma proteins which are produced during
certain immune responses?
11. 2 Reasons for higher hematocrit in males
than in females?
12. A significant drop in hematocrit indicates?
13. Occurs when the percentage of RBCs is
abnormally high
14. Before birth, hemopoiesis occurs in the ____
of an embryo and later in the ___, ___, ____
and ____ of a fetus.
15. Becomes the primary site of hemopoiesis in
the last three months before birth?
16. Red bone marrow cells which are derived
from mesenchyme
17. Cells which have the capacity to develop
into many different type of cells
18. Withdrawal of a small amount of red bone
marrow with a fine needle and syringe
19. Removal of a core of red bone marrow with
a large needle
20. Form the reticular fibers which make the
stroma supporting red bone marrow cells
21. Enlarged and leaky capillaries that surround
red bone marrow and fibers.
22. T or F. Formed elements do not divide once
they leave red bone marrow.
23. Cells which differentiate from myeloid stem
cells?
24. T or F. Progenitor cells are no longer
capable of reproducing themselves and are
committed to giving rise to more specific
elements of blood.
25. Hormones which regulate the differentiation
and proliferation of particular progenitor
cells.
26. Increases the number of red blood cell
precursors
27. Cells found between the kidney tubules
responsible for the production of EPO
28. Stimulate proliferation of progenitor cells in
red bone marrow and regulate the activities
of cells involved in non-specific defenses
and immune responses.
29. Artificial form of erythropoietin used in
treating diminished RBC production that
accompanies end-stage kidney disease
30. T or F. Hb molecules are synthesized after
loss of the nucleus.
31. Ringlike non-protein pigment in Hb?
32. The gaseous hormone, ______, produced
by the endothelial cells that line blood
vessels, that binds to Hb and causes
vasodilation
33. RBCs live only for how many days?
34. Production of RBCs starts in the red bone
marrow with a precursor cell called?
35. During the first weeks after birth, the ___,
not the kidneys, produces most EPO.
36. T or F. Agranular leukocytes do not possess
cytoplasmic granules.
37. Describe the nucleus of a lymphocyte?
38. Size of lymphocytes?
39. 3 types of lymphocytes
40. An increase in the number of WBCs above
10,000 per L
41. Process by which WBCs leave the
bloodstream, rolling along the endothelium,
sticking to it and then squeezing into the
endothelial cells?
42. Among WBCs, __________ respond most
quickly respond to tissue destruction by
bacteria
43. Proteins of neutrophils which exhibit a broad
range of antibiotic activity against bacteria
and fungi
44. Under the influence of the hormone ______,
myeloid stem cells develop into
megakaryocyte-colony-forming cells that in
turn develop into precursor cells called
______.
45. Replacement of cancerous or abnormal red
bone marrow with healthy red bone marrow
in order to establish normal blood cell
counts.
46. When arteries or arterioles are damaged,
the circularly arranged smooth muscle in
their walls contracts immediately, a reaction
called?
47. Hormone in platelets that cause proliferation
of vascular endothelial cells, vascular
smooth muscle fibers and fibroblasts.
48. Process of sticking of platelets to parts of a
damaged blood vessel
49. Mass formed by the accumulation and
attachment of a large number of platelets
50. Straw-colored liquid composed of blood
plasma minus the clotting proteins
51. Gel formed when blood is drawn out of the
body; consists of a network of insoluble
fibrin fibers which trap formed elements
52. Process of gel formation, a series of
reactions which culminates in the formation
of fibrin threads
53. In the extrinsic pathway, a tissue protein
called (2), leaks into the blood.
54. Endothelial cells and WBCs produce a
prostaglandin called _______ that opposes
the actions of thromboxane A2.
55. Blocks the action of several factors,
including XII, X and II.
56. An anticoagulant produced by mast cells
and basophils which combines with anti-
thrombin and increases its effectiveness in
blocking thrombin.
57. Autoimmune condition in which the RBCs of
the fetus have been targeted and lysed by
the mothers antibodies
58. Characterized by an enlarged brain,
edematous and yellow
59. Diagnostic test for HDN (Hemolytic Disease
of the Newborn)
60. A condition where abnormal amounts of fluid
build up in two or more body areas causing
swelling
61. Group of hereditary hemolytic anemias
associated with deficient Hgb synthesis
62. In HbS, glutamic acid is replaced by _____
63. Piling up of too many RBCs trying to enter
small BVs
64. Also known as the Kissing virus