MATERIAL SAFETY DATA SHEET

2-CHLORO-5-(TRICHLOROMETHYL)PYRIDINE
Emergency Phone: 800-992-5994
Dow AgroSciences LLC
Indianapolis, IN 46268
Effective Date: 3/10/03
Product Code: 49728
MSDS: 004942
1
1. PRODUCT AND COMPANY IDENTIFICATION:
PRODUCT: 2-Chloro-5-(Trichloromethyl)Pyridine
COMPANY IDENTIFICATION:
Dow AgroSciences
9330 Zionsville Road
Indianapolis, IN 46268-1189
2. COMPOSITION/INFORMATION ON INGREDIENTS:
2-Chloro-5- CAS#069045-78-9 96.0%
trichloromethylpyridine
2,3,6-trichloropyridine CAS# 006515-09-9 0.2%
Related chlorinated pyridines 3.8%
This document is prepared pursuant to the OSHA Hazard
Communication Standard (29 CFR 1910.1200). In addition,
other substances not Hazardous per this OSHA Standard
may be listed. Where proprietary ingredient shows, the
identity may be made available as provided in this
standard.
3. HAZARDOUS IDENTIFICATIONS:
EMERGENCY OVERVIEW
Hazardous Chemical. White solid. May cause eye irritation
with corneal injury. May cause skin irritation, even a burn.
Oral LD
50
is between 500 and 1000 mg/kg.
EMERGENCY PHONE NUMBER: 800-992-5994
POTENTIAL HEALTH EFFECTS: This section includes
possible adverse effects, which could occur if this material
is not handled in the recommended manner.
EYE: May cause slight eye irritation. May cause slight
temporary corneal injury.
SKIN: Prolonged or repeated exposure may cause skin
irritation, even a burn. May cause more severe response if
skin is damp. Prolonged skin contact is unlikely to result in
absorption of harmful amounts. The dermal LD
50
has not
been determined. Has caused allergic skin reactions when
tested in guinea pigs.
INGESTION: Low toxicity if swallowed. The oral LD
50
for
rats is between 500 and 1000 mg/kg. Small amounts
swallowed incidental normal handling operations are not
likely to cause injury. Observations in animals include liver
and kidney effects.
INHALATION: Prolonged exposure is not expected to
cause adverse effects.
SYSTEMIC (OTHER TARGET ORGAN) EFFECTS:
In animals, effects have been reported on the following
organ: liver.
CANCER INFORMATION: No relevant information found.
TERATOLOGY (BIRTH DEFECTS): No relevant
information found.
REPRODUCTIVE EFFECTS: No relevant information
found.
4. FIRST AID:
EYES: Flush eyes thoroughly with water for several
minutes. Remove contact lenses after initial 1-2 minutes
and continue flushing for several additional minutes. If
effects occur, consult a physician, preferably an
ophthalmologist.
SKIN: Remove material from skin immediately by washing
with soap and plenty of water. Remove contaminated
clothing and shoes while washing. Seek medical attention if
irritation persists. Wash clothing before reuse. Discard
items, which cannot be decontaminated, including leather
articles such as shoes, belts, and watchbands.
INGESTION: If swallowed, seek medical attention. Do not
induce vomiting unless directed to do so by medical
personnel.
INHALATION: Move person to fresh air; if effects occur,
consult a physician.
NOTE TO PHYSICIAN: If burn is present, treat as any
thermal burn, after decontamination. No specific antidote.
Treatment of exposure should be directed at the control of
symptoms and the clinical condition of the patient.
5. FIRE FIGHTING MEASURES:
FLASH POINT: Information not available
METHOD USED: Information not available
MATERIAL SAFETY DATA SHEET
2-CHLORO-5-(TRICHLOROMETHYL)PYRIDINE
Emergency Phone: 800-992-5994
Dow AgroSciences LLC
Indianapolis, IN 46268
Effective Date: 3/10/03
Product Code: 49728
MSDS: 004942
2
FLAMMABLE LIMITS
LFL: Information not available
UFL: Information not available
EXTINGUISHING MEDIA: CO
2
, dry chemical
FIRE AND EXPLOSION HAZARDS: If product is involved
in fire, noxious, toxic fumes may be produced.
FIRE-FIGHTING EQUIPMENT: Wear positive-pressure,
self-contained breathing apparatus and full protective
clothing.
6. ACCIDENTAL RELEASE MEASURES:
ACTION TO TAKE FOR SPILLS: Wear protective clothing
to avoid contact during cleanup of spills and leaks. Sweep
up or otherwise collect spilled material for disposal. Do not
use water for cleanup. Report large spills to Dow
AgroSciences at 800-992-5994.
7. HANDLING AND STORAGE:
PRECAUTIONS TO BE TAKEN IN HANDLING AND
STORAGE: Avoid contact with eyes, skin and clothing.
Wash thoroughly after handling. Store in the original
container in a dry area.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION:
These precautions are suggested for conditions where the
potential for exposure exists. Emergency conditions may
require additional precautions.
EXPOSURE GUIDELINE(S):
2-Chloro-5 trichloromethylpyridine (2-Tet): Dow
AgroSciences Industrial Hygiene Guide is 0.1 ppm.
ENGINEERING CONTROLS: Provide general and/or local
exhaust ventilation to control airborne levels below the
exposure guidelines.
RECOMMENDATIONS FOR MANUFACTURING,
COMMERCIAL BLENDING, AND PACKAGING
WORKERS:
RESPIRATORY PROTECTION: Atmospheric levels should
be maintained below the exposure guideline.
SKIN PROTECTION: Use protective clothing chemically
resistant to this material. Selection of specific items such as
faceshield, gloves, boots, apron or full-body suit will depend
on operation. Remove contaminated clothing immediately,
wash skin area with soap and water, and launder clothing
before reuse or dispose of properly. Items, which cannot be
decontaminated, such as shoes, belts and watchbands,
should be removed and disposed of properly.
EYE/FACE PROTECTION: Use safety glasses.
APPLICATORS AND ALL OTHER HANDLERS: Refer to
the product label for personal protective clothing and
equipment.
9. PHYSICAL AND CHEMICAL PROPERTIES:
BOILING POINT: 266
o
C, (511
o
F)
VAPOR PRESSURE: Low
VAPOR DENSITY: Information not available
SOLUBILITY IN WATER: Very low
SPECIFIC GRAVITY: Not applicable
MELTING POINT: 53
o
-55
o
C, (127
o
-131
o
F)
APPEARANCE: White solid at room temperature
0ODOR: Information not available
10. STABILITY AND REACTIVITY:
STABILITY: (CONDITIONS TO AVOID) High
temperatures, such as open flame and welding arcs, may
induce thermal decomposition.
INCOMPATIBILITY: (SPECIFIC MATERIALS TO AVOID)
Do not store in unlined containers. Avoid contact with
metals such as aluminum and magnesium.
HAZARDOUS DECOMPOSITION PRODUCTS: Thermal
decomposition will lead to formation of hydrogen chloride
and other toxic gases.
HAZARDOUS POLYMERIZATION: Not known to occur.
11. TOXICOLOGICAL INFORMATION:
MUTAGENICITY: In-vitro mutagenicity studies were
negative in some cases and positive in other cases.
MATERIAL SAFETY DATA SHEET
2-CHLORO-5-(TRICHLOROMETHYL)PYRIDINE
Emergency Phone: 800-992-5994
Dow AgroSciences LLC
Indianapolis, IN 46268
Effective Date: 3/10/03
Product Code: 49728
MSDS: 004942
3
12. ECOLOGICAL INFORMATION:
ENVIRONMENTAL FATE
MOVEMENT & PARTITIONING:
Bioconcentration potential is moderate (BCF between 100
and 3000 or Log Pow between 3 and 5).
Log octanol/water partition coefficient (log Pow) is
estimated using a structural fragment method to be 3.35.
Log octanol/water partition coefficient (log Pow) is
estimated to be 3.39.
Henry's Law Constant (H) is estimated to be 1059E-05 atm-
m3/mol.
Potential for mobility in soil is low (Koc between 500 and
2000).
Soil organic carbon/water partition coefficient (Koc) is
estimated to be 1560.
DEGRADATION & PERSISTENCE:
Biodegradation under aerobic static laboratory conditions is
low.
(BOD20 or BOD28/ThOD between 2.5 and 10%).
5-Day biochemical oxygen demand (BOD5) is 0.04 p/p.
10-Day biochemical oxygen demand (BOD10) is 0.05 p/p.
28-Day biochemical oxygen demand (BOD28) is 0.12 p/p.
Theoretical oxygen demand (ThOD) is calculated to be
0.97 p/p.
ECOTOXICOLOGY:
Not expected to be acutely toxic to aquatic organisms.
Acute LC
50
in fathead minnow (Pimephales promelas) is
>99 mg/L.
Acute LC
50
in water flea (Daphnia magna) is >99 mg/L.
13. DISPOSAL CONSIDERATIONS:
DISPOSAL METHOD: If product cannot be recycled,
dispose of by burning in an approved incinerator. Follow all
local, state, and federal requirements for disposal. Contact
Dow AgroSciences for further information.
14. TRANSPORT INFORMATION:
For DOT regulatory information, if required, consult
transportation regulations, product-shipping papers, or
contact your Dow AgroSciences representative.
15. REGULATORY INFORMATION:
NOTICE: The information herein is presented in good faith
and believed to be accurate as of the effective date shown
above. However, no warranty, express or implied, is given.
Regulatory requirements are subject to change and may
differ from one location to another; it is the buyers
responsibility to ensure that its activities comply with
federal, state or provincial, and local laws. The following
specific information is made for the purpose of complying
with numerous federal, state or provincial, and local laws
and regulations.
U.S. REGULATIONS
SARA 313 INFORMATION: To the best of our knowledge,
this product contains no chemical subject to SARA Title III
Section 313 supplier notification requirements.
SARA HAZARD CATEGORY: This product has been
reviewed according to the EPA "Hazard Categories"
promulgated under Sections 311 and 312 of the Superfund
Amendment and Reauthorization Act of 1986 (SARA Title
III) and is considered, under applicable definitions, to meet
the following categories:
An immediate health hazard
A delayed health hazard
TOXIC SUBSTANCES CONTROL ACT (TSCA): All
ingredients are on the TSCA inventory or are not required
to be listed on the TSCA inventory.
NOTICE: The following information is required to be
included on the MSDS according to a consent order for
PMN substance P-83-1163 (2,3,6-trichloropyridine), which
is a minor component of this product:
HUMAN HEALTH HAZARD STATEMENTS FOR P-83-
1163: May cause liver effects.
HUMAN HEALTH PRECAUTIONARY STATEMENTS:
Avoid skin contact; avoid breathing the substance; use
respiratory protection; use skin protection.
ENVIRONMENTAL HAZARD STATEMENTS: May be
toxic to fish and toxic to aquatic organisms.
MATERIAL SAFETY DATA SHEET
2-CHLORO-5-(TRICHLOROMETHYL)PYRIDINE
Emergency Phone: 800-992-5994
Dow AgroSciences LLC
Indianapolis, IN 46268
Effective Date: 3/10/03
Product Code: 49728
MSDS: 004942
4
ENVIRONMENTAL HAZARD PRECAUTIONARY
STATEMENTS: Disposal Restrictions apply.
SNUR: 2-Chloro-5-Trichloromethylpyridine is a halogenated
pyridine. The distribution and use of halogenated pyridines
is regulated by a Significant New Use Rule (SNUR)
regarding Premanufacturing Notice 83-1163. (See 40 CFR
721-8675)
STATE RIGHT-TO-KNOW: This product is not known to
contain any substances subject to the disclosure
requirements of:
New Jersey
Pennsylvania
OSHA HAZARD COMMUNICATION STANDARD: This
product is a "Hazardous Chemical" as defined by the OSHA
Hazard Communication Standard, 29 CFR 1910.1200.
NATIONAL FIRE PROTECTION ASSOCIATION (NFPA)
RATINGS:
Category Rating
Health 2
Flammability 1
Reactivity 0
COMPREHENSIVE ENVIRONMENTAL RESPONSE
COMPENSATION AND LIABILITY ACT (CERCLA, or
SUPERFUND): To the best of our knowledge, this product
contains no chemical subject to reporting under CERCLA.
16. OTHER INFORMATION:
MSDS STATUS: Revised Section: 3, 4, 8 & 12
Reference: DR-0178-0150
Replaces MSDS dated: 9/13/00
The Information Herein Is Given In Good Faith, But No
Warranty, Express or Implied, Is Made. Consult Dow
AgroSciences for Further Information.