FC Derm (SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa 27 August 2012 Paper 1 (3 hours)
All questions to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer)

a) b)

Write short notes on disseminated intravascular coagulation. (10) Write short notes on methods that may be employed to detect infective organisms in formalin-fixed skin biopsy specimens. (15) [25] The distribution and functions of melanocytes in the skin. The components and role of innate immunity. The pathogenesis of atopic eczema. (8) (9) (8) [25]

a) b) c)

Write short notes on the factors that could influence the following a) Structure and appearance of the nail unit. (8) b) Skin thickness. (9) c) The healing of a wound in a 75-year-old man with a traumatic injury of the leg. (8) [25] a) Describe in detail the anatomical structure, distribution and function of the eccrine, apocrine sweat glands and sebaceous glands. (10) b) Comment on changes that occur in the apocrine, eccrine and sebaceous glands during the human life cycle. (5) c) Discuss clinical conditions that affect the apocrine and eccrine glands. (10) [25]

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FC Derm (SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa 28 August 2012 Paper 2 (3 hours)
All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer)

Discuss a) The difference between necrosis and apoptosis. b) The different types of necrosis with the aid of examples. c) Atrophy and its relevance to ageing. d) Hyperplasia and its relevance to the skin .

(5) (10) (5) (5) [25]

Write short notes on the following a) The mechanisms of spread by malignant neoplasm. (7) b) The differences between an ephelis, a lentigo, a melanocytic naevus and a melanoma. (6) c) Routine histochemical stains commonly employed in the evaluation of skin biopsy specimens, citing examples of the possible diagnostic applications thereof. (12) [25] Write notes on the following a) The skin as a target organ for hormone action, (give specific examples where appropriate). (10) b) Control of skin blood flow. (10) c) Nociceptors in the skin. (5) [25] a) b) c) Write notes on the anatomy and function of the Pacinian corpuscle . (5) Discuss the cross sectional anatomy of the anagen hair follicle. (10) Discuss the dermo-epidermal junction ultra structure and clinical relevance. (10) [25]

FC Derm (SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa 29 August 2012 Paper 3 (3 hours)

All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer)

Discuss Type III and IV hypersensitivity reactions under the following headings a) Definition. b) Mechanisms. c) List examples that are relevant to dermatology.

(4) (15) (6) [25]

Describe the physiological role of the skin in a) Defence against infection. b) Regulation of body temperature. c) Calcium homeostasis.

(10) (10) (5) [25]

Write notes on Langerhans cells in the epidermis a) The general biology and origin. (5) b) Structure including the ultrastructure. (4) c) Main functions. (10) d) The important histochemical methods used to identify Langerhans cells in the epidermis. (6) [25] a) b) Write notes describing the embryonic development of the epidermis. Write notes describing the embryonic development of the dermis. (15) (10) [25]

NB: Please not do not write about the development of the epidermal derivatives or the junction between the epidermis and dermis.