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MATERIAL SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

1. Identification of the substance/mixture and of the company/undertaking


1.1 Product identifier Trade name Substance name Substance No. : BUTADIENE : 1,3-Butadiene : 203-450-8 (EINECS)

1.2 Relevant identified uses of the substance or mixture and uses advised against Use of the Substance/Mixture : Manufacture of substances, Distribution of substance, Use as intermediate, Formulation, Use as a fuel, Manufacture of rubber products, Polymer production, Polymer processing, Use in laboratories

1.3 Details of the supplier of the safety data sheet


Company Basell Polyolefine GmbH Brhler Strae 60 D-50389 Wesseling Germany Socit du Craqueur de L'Aubette S.A.S. B.P. 14 13131 Berre l'Etang Cedex France Compagnie Petrochemique de Berre S.A.S Chemin Departemental 21A 13130 Berre l'Etang Cedex France Telephone +49 (0)2236 72 0 Registration number 01-2119471988-16-0007

1.4 Emergency telephone


Emergency telephone +49(0)2236 72 2555

+33 (0) 4 42 74 42 74

01-2119471988-16

Site Number: +33 (0) 4 42 74 42 74 Poison control: +33 (0) 4 91 75 25 25

+33(0)8 20 30 03 35

01-2119471988-16-0008

Site Number: +33 (0) 4 42 74 42 74 Poison control: +33 (0) 4 91 75 25 25

E-mail address Responsible/issuing person

: product.safety@lyondellbasell.com

2. Hazards identification
2.1 Classification of the substance or mixture Classification (REGULATION (EC) No 1272/2008) Flammable Gases, Category 1 Germ cell mutagenicity, Category 1B Carcinogenicity, Category 1A Classification (67/548/EEC, 1999/45/EC) 1 / 39 H220: Extremely flammable gas. H280: Contains gas under pressure; may explode if heated. H340: May cause genetic defects. H350: May cause cancer.

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Extremely flammable. Toxic.

R12: Extremely flammable. R45: May cause cancer. R46: May cause heritable genetic damage.

2.2 Label elements Labeling (REGULATION (EC) No 1272/2008) Hazard pictograms :

Signal Word Hazard Statements

: :

Danger H220 H280 H340 H350 Extremely flammable gas. Contains gas under pressure; may explode if heated. May cause genetic defects. May cause cancer.

Precautionary Statements

Prevention: P202 P210 P281 Response: P377 P381 Storage: P410 + P403

Do not handle until all safety precautions have been read and understood. Keep away from open flames/hot surfaces. - No smoking. Use personal protective equipment as required. Leaking gas fire: Do not extinguish, unless leak can be stopped safely. Eliminate all ignition sources if safe to do so. Protect from sunlight. Store in a wellventilated place.

2.3 Other hazards This substance is not considered to be persistent, bioaccumulating nor toxic (PBT). This substance is not considered to be very persistent nor very bioaccumulating (vPvB).

3. Composition/information on ingredients
3.1 Substances Chemical Name 1,3-butadiene CAS-No. EINECS-No. / ELINCS No./EC-No. 106-99-0 203-450-8 Concentration [%] >= 99

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MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

4. First aid measures


4.1 Description of first-aid measures General advice : This product is of low acute toxicity. May cause cancer by inhalation. Product is genotoxic. Contact with liquid may cause frostbite. Always observe self-protection methods Move out of dangerous area. Remove contaminated clothes except in the case of frostbite. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Show this material safety data sheet to the doctor in attendance. : Remove victim to fresh air and keep at rest in a position comfortable for breathing. Do not leave the victim unattended. Keep patient warm and at rest. Immediately seek medical attention. If breathing is difficult, give oxygen. If unconscious place in recovery position and seek medical advice. In the event of unconsciousness, apnea or cardiac arrest (no pulse) apply cardiopulmonary resuscitation. : Non-irritating to the skin. Dermal contact with rapidly evaporating liquid could result in freezing of the tissues or frostbite. If frostbite has not occurred, immediately flush affected area with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. If frostbite has occurred, seek medical attention immediately; do not rub the affected area or flush with water. To prevent further damage, do not attempt to remove frozen clothing from affected area. Get medical attention immediately if irritation persists. : If eye tissue is frozen, seek medical attention immediately. If tissue is not frozen, thoroughly flush the eyes with large amounts of clean low-pressure water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation persists seek medical attention. : Ingestion is not a route of exposure for gases.

If inhaled

In case of skin contact

In case of eye contact

If swallowed

4.2 Most important symptoms and effects, both acute and delayed Symptoms : Inhalation of very high concentrations may cause asphyxia, anesthesia, CNS depresssion (primarily fatigue, dizziness and loss of concentration, with collapse, coma and death in cases of severe overexposure), and possible cardiac sensitization. 3 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Hazards

: Epinephrine and other sympathomimetic drugs may initiate cardiac arrhythmias (irregular beating) in persons exposed to this material. Skin or eye contact with rapidly evaporating liquid could result in freezing of the tissues or frostbite.

4.3 Indication of immediate medical attention and special treatment needed Treatment : Treat symptomatically. Treatment of overexposure should be directed at the control of symptoms and the clinical condition of the patient. Treat frost-bitten areas as needed.

5. Fire-fighting measures
5.1 Extinguishing media Suitable extinguishing media : SMALL FIRE: Use dry chemical, CO2, water spray or regular foam. LARGE FIRE: Use water spray, water fog or regular foam. Do not use straight streams. : Do not extinguish a leaking gas fire unless leak can be stopped.

Unsuitable extinguishing media

5.2 Special hazards arising from the substance or mixture Specific hazards during fire fighting : May polymerize explosively when involved in a fire. Vapors may travel long distances along the ground before reaching a source of ignition and flashing back. Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety devices; icing may occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. Always stay away from tanks engulfed in fire. For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn. Move containers from fire area if you can do it without risk. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. Thermal decomposition may produce oxides of carbon and other toxic gases and liberate heat and pressure. Reacts with air to form peroxides.

5.3 Precautions for fire-fighters Special protective equipment for fire-fighters Further information : Wear an approved positive pressure self-contained breathing apparatus and firefighter turnout gear. : Use water spray to cool unopened containers. 4 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

6. Accidental release measures


6.1 Personal precautions, protective equipment and emergency procedures Personal precautions : Use personal protective equipment. Eliminate all sources of ignition. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Spillages of liquid product will create a fire hazard and form an explosive atmosphere Avoid direct contact with released material. Stay upwind. Keep non-involved personnel away from the area of spillage.

6.2 Environmental precautions Environmental precautions : An authoritative evaluation of environmental exposure and risk indicates that no special risk management practices are needed to control environmental release.

6.3 Methods and materials for containment and cleaning up Methods for cleaning up : Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13). Eliminate all sources of ignition. Let evaporate. All equipment used when handling this product must be grounded. Stop leak if you can do it without risk. Isolate area until gas has dispersed. Water spray may reduce vapor; but may not prevent ignition in closed spaces. Prevent entry into waterways, sewers, basements or confined areas. Caution: When in contact with refrigerated/cryogenic liquids, many materials become brittle and are likely to break without warning.

6.4 Reference to other sections See section 8 for additional PPE information., See section 13 for disposal information.

7. Handling and storage


7.1 Precautions for safe handling Advice on safe handling : Do not handle near heat, sparks, or open flame. Do not enter storage areas unless adequately ventilated. Metal containers involved in the transfer of this material should be grounded and bonded. Bonding and grounding measures may not be enough if nonconductive flammables are involved. Check atmosphere for explosiveness and oxygen deficiencies. 5 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Wear recommended personal protective equipment. Handle empty containers with care; vapor residue may be flammable/explosive. Isolate, vent, drain, wash and purge systems or equipment before maintenance or repair. All equipment must conform to applicable electrical code. Use only non-sparking tools. Do not pressurize, cut, weld, braze solder, drill, or grind on containers. While moving cylinder, always keep in place removable valve cover. Securely chain cylinders when in use and protect against physical damage. Do not pressurize or expose empty containers to open flame, sparks, or heat. Do not enter areas where used or stored until adequately ventilated. Advice on protection against fire and explosion Fire-fighting class : Take precautionary measures against static discharge. : Extremely flammable gas.

7.2 Conditions for safe storage, including any incompatibilities Requirements for storage areas and containers : Keep storage containers clean, dry and free of oxygen. Store in accordance with the particular national regulations. Oxygen intrusion into the vessel headspace may support the formation of peroxides and promote popcorn polymer growth. Popcorn polymer may plug safety-venting devices, plug lines and foul equipment. Polymer formation may build sufficient mechanical force to rupture equipment. Store in tightly closed containers segregated from oxidizers and other combustible material. Provide electrical equipment with spark resistant construction.

7.3 Specific end uses : (Refer to exposure scenario section for specific information).

8. Exposure controls/personal protection


8.1 Control parameters Occupational Exposure Limits
Component 1,3-butadiene Source US (ACGIH) OEL (NL) NIOSH TWA TWA IDLH Type: 2 ppm 46.2 mg/m3 2,000 ppm Value Note None. None. None.

6 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

DN(M)EL

End Use: Workers Routes of exposure: Inhalation Potential health effects: Long term, Systemic effects Value: 2.21 mg/m3 End Use: General Population Routes of exposure: Inhalation Potential health effects: Long term, Systemic effects Value: 0.0664 mg/m3

DN(M)EL

PNEC

Not applicable (gas).

8.2 Exposure controls Engineering measures Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. Personal protective equipment Respiratory protection : When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. Use only approved supplied air or self-contained breathing apparatus operated in positive pressure mode. If needed, wear a supplied air respirator conforming to a European norm standard such as EN 139 or equivalent. Wear a respirator conforming to EN 371 with Type AX filter designed for low boiling compounds.

Hand protection

: Wear insulated gloves if contact with liquid is possible. The selected gloves must satisfy the European norm standard EN 511 for protection against the cold.

Eye protection

: Safety glasses are the minimum requirements. Use chemical type goggles and face shield when handling liquified gases. The selected goggles or glasses must satisfy the European norm standard EN 166.

Skin and body protection

: Clothing such as insulated impervious gloves to protect against exposure to cold liquid or gas should be worn. Choose body protection according to the amount and concentration of the dangerous substance at the work place. Use PPE that is chemical resistant to the product and prevents skin contact. Fire retardant clothing is appropriate for routine occupational use. 7 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

The selected clothing must satisfy the European norm standard EN 533. Hygiene measures : Selection of appropriate personal protective equipment should be based on an evaluation of the performance characteristics of the protective equipment relative to the task(s) to be performed, conditions present, duration of use, and the hazards and/or potential hazards that may be encountered during use. Consult the appropriate European norm (EN) standard before deciding on the type of personal protective equipment that is appropriate for a particular set of circumstances. Emergency eye wash fountains and safety showers should be available in the immediate vicinity of any potential exposure. Use good personal hygiene practices. Wash hands before eating, drinking, smoking, or using toilet facilities. Take off contaminated clothing and wash before reuse. Environmental exposure controls General advice : See section 6.

9. Physical and chemical properties


9.1 Information on basic physical and chemical properties Appearance Color Odor Flash point Lower explosion limit : gaseous at 20 C (1,013 hPa) : colorless : Faint, mild hydrocarbon odor. : Note: Not applicable (gas). : 2 vol% Note: (% vol in air). : 12 vol% Note: (% vol in air). : The substance or mixture is not classified as oxidizing. : 420 C

Upper explosion limit

Oxidizing properties Autoignition temperature Molecular Weight pH Melting point/range Freezing point Boiling point/boiling range

: 54.09 g/mol : Note: Not applicable. : -108.9 C Note: no data available : -4.41 C 8 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Density Water solubility

: Note: Not applicable (gas). : 0.735 g/l at 20 C : log Pow: 1.99 : Note: Not applicable (gas). : Note: Not applicable (gas). : Not applicable. : (No chemical groups associated with explosive properties.)

Partition coefficient: noctanol/water Viscosity, dynamic Viscosity, kinematic Explosive properties

9.2 Other information

10. Stability and reactivity


10.1 Reactivity The product is normally supplied in a stabilized form. If the permissible storage period and/or storage temperature is noticeably exceeded, the product may polymerize with heat evolution. 1,3-butadiene may react with oxygen to form unstable butadiene peroxides. Butadiene peroxides are thermally unstable, shock sensitive and may lead to the formation of popcorn polymer. 10.2 Chemical stability This product is stable with an appropriate level of TBC inhibitor (minimum 10 ppm), but reactive (unstable) without. 10.3 Possibility of hazardous reactions Hazardous reactions : Polymerization may take place at elevated temperatures or in the presence of oxidizers. The formation of popcorn polymer can build sufficient mechanical force to rupture process equipment. Polymer may also plug safety venting devices.

10.4 Conditions to avoid Conditions to avoid : All sources of ignition, high temperature and oxygen intrusion into storage and transportation vessels. Elevated temperature or catalysis can cause violent rupture of containers.

10.5 Incompatible materials Materials to avoid : Phenol, ethanol, chlorine dioxide, crotonaldehyde, nitric acid, oxygen and other strong oxidizers, and acetylide forming materials such as copper, magnesium, mercury, silver and monel. Contact may form violently explosive peroxides.

10.6 Hazardous decomposition products Hazardous decomposition products : Explosive peroxides. 4-Vinylcyclohexene-1 9 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Thermal decomposition

: Note: Carbon dioxide, carbon monoxide, smoke, fumes and unburned hydrocarbons.

11. Toxicological information


11.1 Information on toxicological effects Acute toxicity Acute oral toxicity Acute inhalation toxicity : Remarks: Not relevant - gas at room temperature. : LC50: 270 mg/l Exposure time: 4 HOURS Species: mouse Remarks: This substance has a low order of acute toxicity by the inhalation route. : Remarks: Not applicable (gas).

Acute dermal toxicity Skin corrosion/irritation Skin irritation

: Classification: Non-irritating to the skin. Remarks: Liquid contact may cause cryogenic burns (frostbite).

Serious eye damage/eye irritation Eye irritation : Classification: No eye irritation Remarks: Liquid contact may cause cryogenic burns (frostbite).

Respiratory or skin sensitization Sensitization Germ cell mutagenicity Remarks : In non-human studies, 1,3-butadiene is genotoxic in vitro and is genotoxic in vivo in both somatic and germ cells in the mouse. The available data on several groups of 1,3butadiene-exposed workers did not show any association between 1,3-butadiene exposure and increased gene mutations, primarily HPRT mutations. No 1,3-butadienerelated chromosome aberrations have been demonstrated in humans. : Remarks: Not expected to be a sensitizer.

Carcinogenicity Remarks : Human carcinogen.,May cause cancer.,Animal data demonstrate marked species difference in carcinogenic response to butadiene. In the mouse, long term inhalation exposure is associated with an increased incidence of benign and malignant cancers in a wide range of tissues, whereas a more limited tumor profile is seen in the rat. Epidemiology studies suggest butadiene may be carcinogenic in humans 10 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

with a concern for cancers of the lymphohematopoietic system.

Reproductive toxicity

Remarks

: There is no evidence that 1,3-butadiene has an adverse effect on fertility in the mouse, rat or other species. It has an adverse effect on germ cells in male mice and the ovary and testes are target organs for 1,3-butadiene toxicity in mice but evidence indicates that fertility is unaffected. ,The available evidence indicates that 1,3-butadiene has low potential for developmental toxicity in humans.1,3-Butadiene caused developmental toxicity in rats and mice, in the presence of maternal toxicity, manifested as retardation in fetal development. There was no evidence of developmental toxicity in the absence of maternal toxicity.

Target Organ Systemic Toxicant - Single exposure : Remarks: The substance or mixture is not classified as specific target organ toxicant, single exposure. Target Organ Systemic Toxicant - Repeated exposure : Target Organs: Heart, Testes, ovary, Liver, Blood, Stomach, Lungs Remarks: 1,3- Butadiene is highly toxic in the mouse, producing lesions in a range of tissues (including ovary, testis, lung, liver, bone marrow, thymus, fore stomach and heart) after repeated inhalation exposure. No comparable changes occurred in rats or other laboratory animal species, hence the relevance of these findings to humans is that it is unclear. Further information : Butadiene is of slight acute toxicity, although inhalation exposure to high concentrations may cause dizziness, CNS depression, loss of consciousness and cardiac sensitization, while concentrated vapors are irritating to the eye and respiratory tract. Clear species differences are apparent in its repeat toxicity profile, with adverse lesions reported in a range of tissues in the mouse, whereas no comparable changes occurred in rats or other species of laboratory animal. It is not a teratogen, however mild fetotoxicity (primarily retarded development) has been observed in rodents and generally at maternally toxic exposures. Adverse changes in the reproductive system of the mouse (including testicular- and ovarian atrophy, and altered sperm head morphology) have been noted following repeated inhalation exposure, but there was no detrimental effect on fertility or reproduction. It induces micronuclei, chromosomal aberrations and dominant lethal mutations in mice after inhalation. Animal data demonstrate that it is carcinogenic in the mouse, inducing benign and malignant cancers in a wide range of tissues, however a more limited tumor profile is seen in the rat. 11 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Epidemiology studies suggest butadiene is carcinogenic in humans with concern for cancers of the lymphohematopoietic system.

12. Ecological information


12.1 Toxicity Toxicity to fish : LC50: 43 - 45 mg/l Exposure time: 96 HOURS Species: fish. Remarks: Based on Quantitative structure-activity relationship (QSAR) estimation.

Toxicity to daphnia and other aquatic invertebrates.

: LC50: 24 - 33 mg/l Exposure time: 48 HOURS Species: Daphnia Remarks: Based on Quantitative structure-activity relationship (QSAR) estimation.

Toxicity to algae

: EC50: 11 - 33 mg/l Exposure time: 96 HOURS Species: algae Remarks: Based on Quantitative structure-activity relationship (QSAR) estimation.

Toxicity to bacteria

: Remarks: no data available : Remarks: no data available : Remarks: No Data Available.

Toxicity to fish (Chronic toxicity) Toxicity to daphnia and other aquatic invertebrates. (Chronic toxicity)

12.2 Persistence and degradability Biodegradability : Remarks: Not readily biodegradable.

12.3 Bioaccumulative potential Bioaccumulation : Remarks: Bioaccumulation is unlikely. 12 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

12.4 Mobility in soil Mobility : Remarks: Not expected to adsorb to soil or sediment due to the low log Kow<3

Distribution among environmental compartments

: Remarks: High degree of volatilization from surface waters and soil is expected, with propylene partitioning mainly to air.

Additional : Remarks: adviceEnvironmental fate Does not undergo hydrolysis. and pathways 12.5 Results of PBT and vPvB assessment This substance is not considered to be persistent, bioaccumulating nor toxic (PBT)., This substance is not considered to be very persistent nor very bioaccumulating (vPvB). 12.6 Other adverse effects Additional ecological information 1,3-butadiene : Due to the physio-chemical characteristics of this material, no reliable test data are available.

13. Disposal considerations


13.1 Waste treatment methods Product : Preferred disposal for this volatile, flammable product is through combustion. Use flare if pressure warrants. Assure emissions comply with applicable regulations. Contaminated product, soil, water, and empty containers may be hazardous wastes due to possible presence of flammable gases. Dispose of in accordance with local regulations. Contaminated product, soil, water, container residues and spill cleanup materials may be hazardous wastes. Proper grounding procedures to avoid static electricity should be followed. The product should not be allowed to enter drains, water courses or the soil.

14. Transport information

IMDG UN-Number

: 1010 13 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Description of the goods Class Labels EmS Number 1 EmS Number 2 Marine pollutant RID UN-Number Description of the goods Transport hazard class(es) Classification Code Hazard identification No Labels Environmentally hazardous

: : : : :

BUTADIENES, STABILIZED, 2.1 2.1 F-D S-U

: no

: : : : : :

1010 BUTADIENES, STABILIZED 2 2F 239 2.1 : no

15. Regulatory information


15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture Water contaminating class (Germany) US (ACGIH) : WGK 2 water endangering

: Known carcinogen. Eczema injuries of an allergic nature. : Not classifiable as a human carcinogen. : Not Classifiable Monograph 60 [1994], Supplement 7 [1987] : Carcinogenic to Humans Monograph 97 [in preparation], Monograph 71 [1999] : known human carcinogen

International Agency for Research on Cancer

National Toxicology Program

Notification status All ingredients are on the following inventories or are exempted from listing
Country Australia Canada China European Union Japan Korea Philippines United States of America New Zealand Notification AICS DSL IECS EINECS ENCS/ISHL ECL PICCS TSCA NZIoC

Contact product.safety@lyondellbasell.com for additional global inventory information.


15.2 Chemical Safety Assessment A Chemical Safety Assessment has been carried out for this substance. 14 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

16. Other information


Material safety datasheet sections which have been updated: Updated with substance registration requirements according to EC 1907/2006 Annex II and (EC) No.1272/2008 CLP. November 29 2010 Full text of R-phrases referred to under sections 2 and 3 R12 R45 R46 Extremely flammable. May cause cancer. May cause heritable genetic damage.

Full text of H-Statements referred to under sections 2 and 3. H220 H280 H340 H350 Extremely flammable gas. Contains gas under pressure; may explode if heated. May cause genetic defects. May cause cancer.

Disclaimer Multiple legal entities and registration numbers may be displayed in Section 1. The Recipient shall refer to the shipping documents to identify the legal entity that supplied this product. This document is generated for the purpose of distributing health, safety, and environmental data. Information is correct to the best of our knowledge at the date of the MSDS publication. It is not a specification sheet nor should any displayed data be construed as a specification. The information on this MSDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, expressed or implied, regarding its correctness. Some information presented and conclusions drawn herein are from sources other than direct test data on the substance itself. The conditions or methods of handling, storage, use and disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage, or expense arising out of or in any way connected with handling, storage, use, or disposal of this product. If the product is used as a component in another product, this MSDS information may not be applicable.

15 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Annex Section 1 Title Use Descriptor

Processes, tasks, activities covered

Section 2 Field for additional statements to explainscenario if required. Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure Contributing Scenarios

Exposure Scenario Title Manufacture of 1,3-butadiene;CAS RN106-99-0 Sector of Use: Industrial (SU3) Process Categories: PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b, PROC15 Environmental Release Categories: ERC1, ERC4 Manufacture of the Substance or use as an intermediate or process chemical or extraction agent. Includes recycling/ recovery, material transfers, storage, sampling, associated laboratory activities, maintenance and loading (including marine vessel/barge, road/rail car and bulk container). Operational conditions and risk management measures

Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures, 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. 16 / 39

General measures (carcinogens) [G18]

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

General exposures (closed systems) [CS15]. General exposures (closed systems)

Handle substance within a closed system [E47].

Handle substance within a predominantly closed system [CS15]. provided with extract ventilation [E49].; With sample collection [CS56]. With Sample via a closed loop or other system to avoid exposure occasional controlled exposure [E8]Provide a good standard of general ventilation (not less [CS137] than 3 to 5 air changes per hour). [E11].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. General exposures (closed systems) Handle substance within a predominantly closed system [CS15]. Use in contained batch provided with extract ventilation [E49].; Sample via a closed processes [CS37]. loop or other system to avoid exposure [E8]; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]; Avoid carrying out activities involving exposure for more than 15 minutes [OC26]. General exposures (open systems) Handle substance within a predominantly closed system [CS16]. Batch process [CS55]. With provided with extract ventilation [E49].; Sample via a closed sample collection [CS56]. loop or other system to avoid exposure [E8]; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]; Avoid carrying out activities involving exposure for more than 15 minutes [OC26]. Process sampling [CS2]. Sample via a closed loop or other system to avoid exposure [E8]Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Avoid carrying out activities involving exposure for more than 15 minutes [OC26]. Laboratory activities [CS36]. Use a high performance fume cupboard [E86], or [G9] alternatively [G10], Handle within a fume cupboard or implement equivalent measures to minimise exposures [E12], Wear a full face respirator conforming to EN140 with Type A filter or better [PPE24] Bulk transfers [CS14]. (open systems) Use dry break couplings for material transfer [E75].Ensure [CS108]With potential for aerosol material transfers are under containment or extract ventilation generation [CS138]. [E66]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Bulk transfers [CS14]. (closed Use dry break couplings for material transfer [E75].Avoid systems) [CS107]; carrying out activities involving exposure for more than 1 hour [OC27]. Equipment cleaning and maintenance Drain down the flush system prior to equipment break-in or [CS39]. maintenance [E55]; Provide extract ventilation to points where emissions occur [E54]; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]; Clear sp[ills immediately [C&H13]; Wear a respirator conforming to EN140 with Type A filter or better. [PPE22]; Retain drain downs in sealed storage pending disposal or for subsequent recycle [ENVT4] Storage [CS67]With occasional Sample via a closed loop or other system to avoid exposure controlled exposure [CS137] [E8]Provide extract ventilation to material transfer points and other openings [E82].; Store substance within a closed system [E84]. Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the 17 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

risks are considered to be controlled for ecological receptors. Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment Section 5 Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Distribution of 1,3-butadiene;CAS RN106-99-0 Sector of Use: Industrial (SU3, SU8, SU9) Process Categories: PROC1, PROC2, PROC3, PROC4, PROC8a, PROC8b, PROC9, PROC15 Environmental Release Categories: ERC1-7 Loading (including marine vessel/barge, rail/road car and IBC loading) and repacking (including drums and small packs) of substance, including its distribution and associated laboratory activities Operational conditions and risk management measures

Processes, tasks, activities covered

Section 2 Field for additional statements to explain scenario if required. Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions

Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a 18 / 39

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BUTADIENE
Version 1.0 Revision Date 11/29/2010

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affecting worker exposure Contributing Scenarios

General measures (carcinogens) [G18]

General exposures (closed systems) [CS15]. General exposures (closed systems) [CS15]. ; With sample collection [CS56]. With occasional controlled exposure [CS137] General exposures (closed systems) [CS15]. Use in contained batch processes [CS37].

good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Handle substance within a closed system [E47]. Handle substance within a closed system [E47].Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a closed system [E47].Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a closed system [E47].Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 4 hours [OC28]Clear transfer lines prior to de-coupling [E39].; Transfer via enclosed lines [E52]. Handle substance within a closed system [E47].Sample via a closed loop or other system to avoid exposure [E8] Use a high performance fume cupboard [E86], or [G9] alternatively [G10], Handle within a fume cupboard or implement equivalent measures to minimise exposures [E12], and, Wear a full face respirator conforming to EN140 with Type A filter or better [PPE24]; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. 19 / 39

General exposures (open systems) [CS16]. Batch process [CS55]. ; With sample collection [CS56].

Process sampling [CS2]. Laboratory activities [CS36].

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Bulk transfers [CS14]. ; (closed systems) [CS107]

Clear transfer lines prior to de-coupling [E39].; Transfer via enclosed lines [E52].Ensure material transfers are under containment or extract ventilation [E66]. Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Bulk transfers [CS14]. ; (open Clear transfer lines prior to de-coupling [E39].; Transfer via systems) [CS108] enclosed lines [E52].Ensure material transfers are under containment or extract ventilation [E66]. Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Drum and small package filling [CS6]. Transfer via enclosed lines [E52].Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].; Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Equipment cleaning and maintenance Drain down and flush system prior to equipment break-in or [CS39]. maintenance [E55].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Clear spills immediately [C&H13]. Retain drain downs in sealed storage pending disposal or for subsequent recycle [ENVT4]. Storage [CS67]With occasional Transfer via enclosed lines [E52].Provide extract ventilation to controlled exposure [CS137] points where emissions occur [E54]. Avoid carrying out activities involving exposure for more than 4 hours [OC28] Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment Is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors. Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment Section 5 Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure

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Version 1.0 Revision Date 11/29/2010

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Selection of relevant RMM Core Phrases

Good practice RMM phrases may be incorporated in this section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Exposure Scenario Title Formulation & (re)packaging of substances and mixtures of 1,3butadiene;CAS RN106-99-0 Sector of Use: Industrial (SU3, SU10) Process Categories: PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9, PROC14, PROC15 Environmental Release Categories: ERC2 Formulation, packing and re-packing of the substance and its mixtures in batch or continuous operations, including storage, materials transfers, mixing, large and small scale packing, maintenance and associated laboratory activities Operational conditions and risk management measures Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in 21 / 39

Section 1 Title Use Descriptor

Processes, tasks, activities covered

Section 2 Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure Contributing Scenarios

General measures (carcinogens) [G18]

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20].

General exposures (closed systems) [CS15]. General exposures (closed systems) [CS15]. ; With sample collection [CS56]. With occasional controlled exposure [CS137]

Handle substance within a closed system [E47]. Handle substance within a closed system [E47].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a closed system [E47].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Formulate in enclosed or ventilated mixing vessels [E46].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Samlple via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a closed system [E47].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a closed system [E47].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Use High Performance fumecupboard [E86]; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Clear transfer lines prior to de-coupling [E39].; Transfer via enclosed lines [E52].Ensure material transfers are under containment or extract ventilation [E66].

General exposures (closed systems) [CS15]. Use in contained batch processes [CS37].

General exposures (open systems) [CS16]. Batch process [CS55]. ; With sample collection [CS56]. ; With potential for aerosol generation [CS138].

Batch processes at elevated temperatures [CS136].

Process sampling [CS2].

Laboratory activities [CS36].

Bulk transfers [CS14].

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Mixing operations (open systems) [CS30]. With potential for aerosol generation [CS138].

Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Wear a respirator conforming to EN140 with Type A filter or better. [PPE22] Manual [CS34]. ; Transfer Use drum pumps or carefully pour from container [E64].Provide from/pouring from containers [CS22]. extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid spillage when withdrawing pump [C&H16]. Avoid carrying out activities involving exposure for more than 4 hours [OC28] Drum/batch transfers [CS8]. Use drum pumps or carefully pour from container [E64].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Production or preparation or articles Limit the substance content in the product to 1% by tabletting, compression, extrusion [OC16].Provide a good standard of general or controlled or pelletisation [CS100] ventilation (10 to 15 air changes per hour) [E40].Wear a respirator conforming to EN140 with Type A filter or better. [PPE22] Drum and small package filling [CS6]. Clear transfer lines prior to de-coupling [E39].; Transfer via enclosed lines [E52].Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Equipment cleaning and maintenance Drain down and flush system prior to equipment break-in or [CS39]. maintenance [E55].Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Apply vessel entry procedures including use of forced supplied air [AP15]. Wear a respirator conforming to EN140 with Type A filter or better. [PPE22] Storage [CS67]With occasional Provide a good standard of general or controlled ventilation (10 controlled exposure [CS137] to 15 air changes per hour) [E40].; Ensure material transfers are under containment or extract ventilation [E66]. ; Store substance within a closed system [E84].Avoid carrying out activities involving exposure for more than 4 hours [OC28] Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors. Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment 23 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Section 5

Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Use in Fuels of 1,3-butadiene;CAS RN106-99-0 Sector of Use: Industrial (SU3,) Process Categories: PROC1, PROC2, PROC3, PROC8a, PROC8b, PROC16 Environmental Release Categories: ERC7 Covers the use as a fuel (or fuel additive) and includes activities associated with its transfer, use, equipment maintenance and handling of waste. Operational conditions and risk management measures Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS.

Processes, tasks, activities covered

Section 2 Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure Contributing Scenarios

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General measures (carcinogens) [G18]

Bulk transfers [CS14].

Drum/batch transfers [CS8].

General exposures (closed systems) [CS15]. General exposures (closed systems) [CS15]. With occasional controlled exposure [CS137]

Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Transfer via enclosed lines [E52].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Use drum pumps [E53].Provide extract ventilation to material transfer points and other openings [E82].; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Handle substance within a closed system [E47]. Handle substance within a closed system [E47].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 4 hours [OC28] Handle substance within a closed system [E47].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 1 hour [OC27] Handle substance within a predominantly closed system provided with extract ventilation [E49].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a predominantly closed system provided with extract ventilation [E49].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Drain down and flush system prior to equipment break-in or maintenance [E55].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Wear a full face respirator conforming to EN140 with Type A filter or better. [PPE24]

General exposures (closed systems) [CS15]. Batch process [CS55].

General exposures (open systems) [CS16]. ; (closed systems) [CS107]

General exposures (open systems) [CS16]. ; (closed systems) [CS107] Batch process [CS55].

Equipment maintenance [CS5].

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Storage [CS67]

Handle substance within a closed system [E47].No specific measures identified [EI18]. Storage [CS67]With occasional Provide a good standard of general or controlled ventilation (10 controlled exposure [CS137] to 15 air changes per hour) [E40].; Provide extract ventilation to points where emissions occur [E54]. Avoid carrying out activities involving exposure for more than 4 hours [OC28] Disposal of wastes [CS28]. Transfer via enclosed lines [E52].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors. Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment Section 5 Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Use in laboratory reagents of 1,3-butadiene;CAS RN106-99-0 Sector of Use: Industrial (SU3) Process Categories: PROC10, PROC15 Environmental Release Categories: ERC 2, ERC 4 Use of the substance within laboratory settings, including material transfers and equipment cleaningtransfers and equipment cleaning Operational conditions and risk management measures Control of worker exposure 26 / 39

Processes, tasks, activities covered

Section 2 Section 2.1

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure Contributing Scenarios

Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Use high-performance fume cupboard [E86].

General measures (carcinogens) [G18]

Laboratory activities [CS36]. Small scale [CS61]. Handling small quantities (<1000ml) for more than 4 hours/day - inside fume cupboard. Cleaning [CS47]. Rolling, Brushing Provide a good standard of general or controlled ventilation (10 [CS51]. ; Vessel and container to 15 air changes per hour) [E40].; Use high-performance fume cleaning [CS103] Cleaning equiment, cupboard [E86] glassware etc under general ventilation for 15 min - 1 hour/day Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors. 27 / 39

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according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

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Section 3 3.1. Health

Exposure Estimation When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. Guidance to check compliance with the Exposure Scenario Confirm that RMMs and OCs are as described or of equivalent efficiency.

3.2. Environment Section 4 4.1. Health 4.2. Environment Section 5

Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Use in rubber manufacturing and processing of 1,3butadiene;CAS RN 106-99-0 Sector of Use: Industrial (SU3, SU10) Process Categories: PROC1, PROC2, PROC3, PROC4, PROC5, PROC6, PROC7, PROC8a, PROC8b, PROC13, PROC14, PROC21 Environmental Release Categories: ERC 4, ERC 6D Manufacture of tyres and general rubber articles, including processing of raw (uncured) rubber, handling and mixing of rubber additives, vulcanising, cooling and finishing. Operational conditions and risk management measures Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. 28 / 39

Processes, tasks, activities covered

Section 2 Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Contributing Scenarios

General measures (carcinogens) [G18]

Material transfers [CS3]. Material transfers [CS3]. With occasional controlled exposure [CS137] Material transfers [CS3]. Dedicated facility [CS81].Large Containers

Bulk weighing [CS91](closed systems) [CS107]. Bulk weighing [CS91]With occasional controlled exposure [CS137]

Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Handle substance within a closed system [E47]. Transfer via enclosed lines [E52].Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Use drum pumps [E53].Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].; Ensure material transfers are under containment or extract ventilation [E66]. Handle substance within a closed system [E47]. Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 4 hours [OC28] Transfer via enclosed lines [E52].Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 4 hours [OC28] Formulate in enclosed or ventilated mixing vessels [E46].Ensure material transfers are under containment or extract ventilation [E66]. ; Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more 29 / 39

Small scale weighing [CS90] Dedicated facility [CS81].

Additive premixing [CS92] Batch process [CS55]. ; (closed systems) [CS107]

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

than 4 hours [OC28]

Additive premixing [CS92]

Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Material transfers [CS3]. Dedicated Transfer via enclosed lines [E52].Ensure material transfers are facility [CS81]. under containment or extract ventilation [E66]. Material transfers [CS3]. Small Transfer via enclosed lines [E52].Ensure material transfers are Containers under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 4 hours [OC28] Additive premixing [CS92] Mixing Provide extract ventilation to points where emissions occur operations (open systems) [CS30]. [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 15 minutes [OC26] or Wear a respirator conforming to EN140 with Type A filter or better [PPE20]. Calendering (including Banburys) Limit the substance content in the product to 1% [CS64] [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Pressing uncured rubber blanks Limit the substance content in the product to 1% [OC16].Ensure [CS73] material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Vulcanisation [CS70] Limit the substance content in the product to 1% [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Cooling cured articles [CS71] Limit the substance content in the product to 1% [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Laboratory activities [CS36]. Use high-performance fume cupboard [E86]. Drain down and Equipment maintenance [CS5]. flush system prior to equipment break-in or maintenance [E55].Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Wear a respirator conforming to EN140 with Type A filter or better. [PPE22] Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the 30 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

risks are considered to be controlled for ecological receptors. Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment Section 5 Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Use in polymer production of 1,3-butadiene;CAS RN 106-99-0 Sector of Use: Industrial (SU3, SU10) Process Categories: PROC1, PROC2, PROC3, PROC4, PROC5, PROC6, PROC8a, PROC8b, PROC9, PROC14, PROC21 Environmental Release Categories: ERC6A. ERC6C Manufacture of polymers from monomers in continuous and batch processes, include sparging, discharging, and reactor maintenance and immediate polymer product formation (i.e. compounding, pelletisation, product off-gassing). Operational conditions and risk management measures

Processes, tasks, activities covered

Section 2 Field for additional statements to explain scenario if required. Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management

Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable

31 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Other Operational Conditions affecting worker exposure Contributing Scenarios

General measures (carcinogens) [G18]

General exposures (closed systems) [CS15]. Continuous process [CS54]. ; No sampling [CS57]. Bulk transfers [CS14]. Transport [CS58]. ; With sample collection [CS56].

Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Handle substance within a closed system [E47].

Polymerisation (bulk and batch) [CS65]Continuous process [CS54]. ; With sample collection [CS56].

Polymerisation (bulk and batch) [CS65]Batch process [CS55]. ; With sample collection [CS56]. Elevated Temperature

Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 4 hours [OC28] Handle substance within a closed system [E47].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Provide extract ventilation to points where emissions occur [E54]. ; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Handle substance within a closed system [E47].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Provide extract ventilation to points where emissions occur [E54]. ; Sample via a closed loop or other system to avoid exposure [E8]Avoid carrying out activities involving exposure for more than 1 hour [OC27].

32 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Finishing operations [CS102] Batch process [CS55]. ; With sample collection [CS56].

Intermediate polymer storage [CS66]

Additivation and stabilisation [CS69]

Mixing in containers [CS23]. Batch process [CS55].

Pelletizing [CS53]. Extrusion and masterbatching [CS88]

Pelletizing [CS53].

Pelletisation and pellet screening [CS68](open systems) [CS108] Bulk transfers [CS14]. Continuous process [CS54]. ; With sample collection [CS56].

Transport [CS58]. With sample collection [CS56]. Equipment maintenance [CS5].

Limit the substance content in the product to 5% [OC17].; Handle substance within a closed system [E47].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Provide extract ventilation to points where emissions occur [E54]. ; Sample via a closed loop or other system to avoid exposure [E8] Limit the substance content in the product to 5% [OC17].; Handle substance within a closed system [E47].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8] Limit the substance content in the product to 5% [OC17].; Handle substance within a closed system [E47].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8] Handle substance within a closed system [E47].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8] Limit the substance content in the product to 1% [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Limit the substance content in the product to 1% [OC16].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Limit the substance content in the product to 1% [OC16].Ensure material transfers are under containment or extract ventilation [E66]. Handle substance within a closed system [E47].Ensure material transfers are under containment or extract ventilation [E66]. ; Sample via a closed loop or other system to avoid exposure [E8]; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Ensure material transfers are under containment or extract ventilation [E66]. Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Drain down and flush system prior to equipment break-in or maintenance [E55].Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Clear spills immediately [C&H13]. Avoid carrying out activities involving exposure for more than 4 hours [OC28]Wear a respirator conforming to EN140 with Type A filter or better. [PPE22]Retain drain downs in sealed storage pending disposal or for subsequent recycle [ENVT4].

33 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Storage [CS67]With occasional controlled exposure [CS137]

Provide extract ventilation to points where emissions occur [E54]. ; Sample via a closed loop or other system to avoid exposure [E8]; Store substance within a closed system [E84].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors. Section 3 3.1. Health Exposure Estimation When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. Guidance to check compliance with the Exposure Scenario Confirm that RMMs and OCs are as described or of equivalent efficiency.

3.2. Environment Section 4 4.1. Health 4.2. Environment Section 5

Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Use in polymer processing of 1,3-butadiene;CAS RN106-99-0 Sector of Use: Industrial (SU3, SU10) Process Categories: PROC1, PROC2, PROC3, PROC4, PROC5, PROC6, PROC8a, PROC8b, PROC9, PROC13, PROC14, PROC21 Environmental Release Categories: ERC 4 Processing of formulated polymers including material transfers, additives handling (e.g. pigments, stabilisers, fillers, plasticisers, etc.), moulding, curing and forming activities, material re-works, storage and associated maintenance. Operational conditions and risk management measures Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. 34 / 39

Processes, tasks, activities covered

Section 2 Section 2.1 Product characteristics Physical form of product

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure Contributing Scenarios

Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Handle substance within a closed system [E47]. Limit the substance content in the product to 1% [OC16].; Handle substance within a closed system [E47].Ensure material transfers are under containment or extract ventilation [E66]. Limit the substance content in the product to 1% [OC16].Ensure material transfers are under containment or extract ventilation [E66]. Handle substance within a closed system [E47]. Limit the substance content in the product to 1% [OC16].Provide extract ventilation to points where emissions occur [E54]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Limit the substance content in the product to 1% [OC16].Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. 35 / 39

General measures (carcinogens) [G18]

Bulk transfers [CS14]. ; (closed systems) [CS107] Bulk transfers [CS14]. ; (closed systems) [CS107] With occasional controlled exposure [CS137] Bulk transfers [CS14]. Dedicated facility [CS81]. Bulk weighing [CS91](closed systems) [CS107]. Bulk weighing [CS91]With occasional controlled exposure [CS137]

Small scale weighing [CS90]

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Additive premixing [CS92](closed systems) [CS107]

Limit the substance content in the product to 1% [OC16].; Handle substance within a closed system [E47].Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Additive premixing [CS92](open Limit the substance content in the product to 1% [OC16].Ensure systems) [CS108]; With sample material transfers are under containment or extract ventilation collection [CS56]. [E66]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Additive premixing [CS92]General Limit the substance content in the product to 1% [OC16].Ensure exposures (open systems) [CS16]. material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Bulk transfers [CS14]. Drum/batch Limit the substance content in the product to 1% [OC16].Ensure transfers [CS8]. material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Bulk transfers [CS14]. Small package Transfer via enclosed lines [E52].; Limit the substance content filling [CS7]. in the product to 1% [OC16].Ensure material transfers are under containment or extract ventilation [E66]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Calendering (including Banburys) Limit the substance content in the product to 1% [CS64] [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Production of articles by dipping and Limit the substance content in the product to 1% pouring [CS113]. [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Extrusion and masterbatching [CS88] Limit the substance content in the product to 1% [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Injection moulding of articles [CS89] Restrict area of openings to equipment [E68].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Equipment maintenance [CS5]. Drain down system prior to equipment break-in or maintenance [E65].Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40]. Storage [CS67]With occasional Limit the substance content in the product to 1% [OC16].Store controlled exposure [CS137] substance within a closed system [E84].; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The 36 / 39

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment Section 5 Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Section 1 Title Use Descriptor Exposure Scenario Title Use in polymer processing of 1,3-butadiene;CAS RN 106-99-0 Sector of Use: Professional (SU22) Process Categories: PROC1, PROC2, PROC8a, PROC8b, PROC14, PROC21 Environmental Release Categories: ERC 8A, ERC 8D Processing of formulated polymers including material transfers, moulding and forming activities, material re-works and associated maintenance. Operational conditions and risk management measures Control of worker exposure Liquid, vapour pressure > 10 kPa [OC5]. Covers percentage substance in the product up to 100 % (unless stated differently) [G13]. Not applicable Covers daily exposures up to 8 hours (unless stated differently) [G2] Not applicable Assumes use at not > 20C above ambient [G15]; Assumes a good basic standard of occupational hygiene is implemented [G1]. 37 / 39

Processes, tasks, activities covered

Section 2 Section 2.1 Product characteristics Physical form of product Concentration of substance in product Amounts used Frequency and duration of use Human factors not influenced by risk management Other Operational Conditions affecting worker exposure

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Contributing Scenarios

General measures (carcinogens) [G18]

Bulk transfers [CS14]. ; (closed systems) [CS107] Bulk transfers [CS14]. ; (closed systems) [CS107] With occasional controlled exposure [CS137]

Risk Management Measures Note: list RMM standard phrases according to the control hierarchy indicated in the ECHA template: 1. Technical measures to prevent release, 2. Technical measures to prevent dispersion, 3. Organisational measures , 4. Personal protection. Phrases between brackets are good practice advice only, beyond REACH Chemical Safety Assessment and may be communicated in Section 5 of the ES or within the main sections of the SDS. Consider technical advances and process upgrades (including automation) for the elimination of releases. Minimise exposure using measures such as closed systems, dedicated facilities and suitable general / local exhaust ventilation. Drain down systems and clear transfer lines prior to breaking containment. Clean / flush equipment, where possible, prior to maintenance. Where there is potential for exposure: Restrict access to authorised persons; provide specific activity training to operators to minimise exposures; wear suitable gloves and coveralls to prevent skin contamination; wear respiratory protection when its use is identified for certain contributing scenarios; clear up spills immediately and dispose of wastes safely. Ensure safe systems of work or equivalent arrangements are in place to manage risks. Regularly inspect, test and maintain all control measures. Consider the need for risk based health surveillance. [G20]. Handle substance within a closed system [E47]. Limit the substance content in the product to 1% [OC16].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Ensure material transfers are under containment or extract ventilation [E66]. Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Limit the substance content in the product to 1% [OC16].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].; Ensure material transfers are under containment or extract ventilation [E66]. Avoid carrying out activities involving exposure for more than 1 hour [OC27]. Limit the substance content in the product to 1% [OC16].Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation at openings [E60]. ; Provide a good standard of general or controlled ventilation (10 to 15 air changes per hour) [E40].Avoid carrying out activities involving exposure for more than 1 hour [OC27] No specific measures identified [EI18]. Drain down and flush system prior to equipment break-in or maintenance [E55].; Limit the substance content in the product to 1% [OC16].Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11].Wear a respirator conforming to EN140 with Type A filter or better. [PPE22] Handle substance within a closed system [E47].; Limit the substance content in the product to 1% [OC16]. 38 / 39

Material transfers [CS3].

Injection moulding of articles [CS89]

Rework of articles [CS86] Equipment maintenance [CS5].

Storage [CS67]

MATERIAL SAFETY DATA SHEET


according to Regulation (EC) No. 1907/2006

BUTADIENE
Version 1.0 Revision Date 11/29/2010

Gen. Variant: SDS_NL Print Date 11/29/2010 MSDS No.: BE227

Storage [CS67]With occasional controlled exposure [CS137]

Limit the substance content in the product to 1% [OC16].Store substance within a closed system [E84].; Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). [E11]. Section 2.2 Control of environmental exposure The exposure of aquatic, terrestrial, sediment and sewage treatment microorganisms is considered to be negligible because the substance partitions primarily to air when found in the environment. Emission of butadiene to the air compartment is regulated by the VOC directive and the carcinogen directive. The limits in place of both of these directives would also limit exposure to ecological receptors. Hence the risks are considered to be controlled for ecological receptors Section 3 Exposure Estimation 3.1. Health When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted DNELs and the resulting risk characterisation ratios are expected to be less than 1. 3.2. Environment Section 4 Guidance to check compliance with the Exposure Scenario 4.1. Health Confirm that RMMs and OCs are as described or of equivalent efficiency. 4.2. Environment Section 5 Additional good practice advice beyond the REACH Chemical Safety Assessment Note: The measures reported in this section have not been taken into account in the exposure estimates related to the exposure scenario above. They are not subject to obligation laid down in Article 37 (4) of REACH. Control of Worker Exposure Selection of relevant Contributing Good practice RMM phrases may be incorporated in this Scenario phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system. Control of environmental exposure Selection of relevant RMM Core Good practice RMM phrases may be incorporated in this Phrases section or consolidated into the main sections of the SDS, depending on the preference of the Registrant and functionality of the available e-SDS system.

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