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CIPA
(Congenital Insensitivity to Pain with Anhidrosis) Congenital
Insensitivity to
Pain with
Anhidrosis
CIPA
Congenital insensitivity to pain with anhidrosis is a condition that most people are born with, it means you cant feel pain and temperature.
Causes of CIPA
This condition is inherited in a recessive pattern, which means both copies of the gene in each cell have mutations. They typically do not show signs and symptoms of the condition.
Risks?
Not feeling pain or temperature. You cant take care of yourself Injuries are very common Eye injuries, fever and burns, infections
Symptoms
Cant feel pain Cant feel heat
Diagnosed
People with congenital insensitivity to pain with anhidrosis (CIPA) should receive a physical exam and provide a family history. During the patient interview, a clinician should focus on the patient's receptiveness to pain and history of injuries.
Treatments
Treatments for CIPA do not always work, there are some cases where naloxone may be used as a treatment. Naloxone is a chemical that acts within the nervous system of the body by blocking the nervous system from causing the inactions that occur within the group of cells that receives the message to initiate the sensation of pain, heat, or cold. Most treatments are hard to narrow down for this condition because each CIPA patient may have other conditions including the absence of sweat glands, nerve fibers, ulcers, and other conditions.
Prognosis
The prognosis is poor. It is unpredictable. Usually patients dont live to be an adult.
How to prevent it
CIPA is not preventable it is proved that it is hereditary
Facts continued
People with CIPA heal slowly from skin and bone injuries. Repeated trauma can lead to chronic bone infections (osteomyelitis) or a condition called Charcot joints, where the bones and tissue surrounding joints are destroyed.
More Facts
Most CIPA patients die by the age of three simply from overheating People with CIPA suffer from untreated ulcerations of the lips, mouth and tongue, dental infections, minor breaks in the bones and other conditions that can lead to infection, that would cause intense pain in any other person It is more common in homogeneous populations Anhidrosis is the inability to sweat
Websites
http://ghr.nlm.nih.gov/condition/congenital-insensitivity-to-pain-withanhidrosis http://ghr.nlm.nih.gov/condition/congenital-insensitivity-to-pain-withanhidrosis#inheritance http://www.sharecare.com/health/genetic-disorders/how-cipa-diagnosed http://www.medhelp.org/posts/Neurology/Genetics-of-CongenitalInsensitivity-to-Pain-with-Anhidrosis-CIPA/show/293378 http://ghr.nlm.nih.gov/condition/congenital-insensitivity-to-pain-withanhidrosis http://house.wikia.com/wiki/CIPA