Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
html
proper disposal of your medication. 4. Forget a dose Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. 5. Chemical properties
Name:Anastrozole Molecular Formula:C17H19N5 CAS Registry Number:120511-73-1 InChI:InChI=1/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h 5-7,11-12H,8H2,1-4H3 Appearance:crystalline solid Molecular Weight:293.37 Density:1.08 g/cm3 Boiling Point:469.7 oC at 760 mmHg Melting Point:81-82 Flash Point:469.7 oC at 760 mmHg Storage Temperature:Store in original container in a cool dark place. Refractive index:1.791 Solubility:Insoluble
Biological Activity:Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active. Usage:An aromatase inhibitor. Used as an antineoplastic.