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Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders. Here we show differential, highly specific, spatially distributed effects of ECT on regional brain structure in two populations: patients with unipolar or bipolar disorder. The mode of action of ECT has even been ascribed to a "barbaric" form of placebo effect.
Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders. Here we show differential, highly specific, spatially distributed effects of ECT on regio…