B.Sc.

Biotechnology Semester V BBT 514: Biometrics and Quality Control (QC)

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Total 45 L
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Application of statistics to biological systems Introduction and brief history, average, mean, mode, median, variation and standard deviation and examples for problem solving. Experimental designs Principles and types of experimental designs, comparison of different designs, replication, randomization, control and tests of significance (students t test, F test, chi square test and ANOVA). Biometrics Introduction and brief history, biometric techniques used in crop improvement; biometrics in relation to biosciences. Major contributions of famous statisticians/biometricians. Polygenic variation Introduction, polygenic characters, type of polygenic variation, source of variability, difference between qualitative and quantitative traits, loss of variability, features of polygenic traits, assessment of variation, some definitions and technical terms for application of biometrics. Correlation in plant breeding Types of correlation. Comparison between simple, partial and multiple correlations. Applications of correlation in breeding. Limitations, some important definitions. Path coefficient analysis Path coefficient and its types, comparison of correlation and path coefficient analysis. Direct, indirect effect and interpretation of results. Diallele analysis Types of diallele crosses, characteristics of a tester, Line X Tester analysis, comparison of Line X Tester analysis and diallele cross. Adaptation in crop plants Some definitions, adaptability, types and causes of adaptation, factors affecting adaptability, types of environmental coadaptation. Stability analysis Different models, comparison of models, advantages of stability analysis, varieties released based on stability analysis. Genetic variances Classification, types of variances and their comparison. Gene action in breeding. Some genetic estimates. Breeding procedures in relation to gene action. Heritability and genetic advance Types of heritability, genetic advance. Advantages and disadvantages of genetic advance. Interpretation of results. Combining ability (CA) Some definitions, types of CA, combining ability and heritability, combining ability and heterosis. Merits and demerits of CA and interpretation of results.

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Heterosis and inbreeding depression Genetic basis, factors affecting and estimation of heterosis and inbreeding depression. Effects of inbreeding and outbreeding. Quality assurance (Q A) Basics of Q.A., sampling procedures, size of sample, collection/analysis, effect of size and heterogeneity on accuracy, standard, control, blank, comparison of results, statistical quality control and reliability. References 1. Stability parameters for comparing varieties, Eberhart, S. A. and Russell, W. A., Crop Sci. 6, 3640 (1966). 2. Statistical Methods for Agricultural Workers, Panse, V. G., Sukhatme, P. V., ICAR, New Delhi (1967). 3. Biometrical Methods in Quantitative Genetic Analysis, Singh, R. K. and Chaudhary, B.D., Kalyani Publications, New Delhi (1985). 4. A Handbook of Agricultural Statistics, Chandel, S.R.S., Anchal Prakashan Mandir, New Delhi (1993). 5. Statistics, Spiegel, M. R. and Stephens, L. J., Tata McGrawHill Publishing Co., New Delhi (1998). 6. Plant Breeding, Allard, R. W., John Wiley & Sons, New York (1999). 7. Plant Breeding, Principles and Methods, Singh, B. D., 7th Edn., Kalyani Publi., New Delhi (2005).

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5L