Drug Name Dosage Indications Mechanism of Action Contraindications Adverse Reaction Nursing Consideration

100mg/5ml 5ml o Mild to moderate pain Unknown. Produces anti- o Contraindicated in CNS : headache, dizziness,
Name: Ibuprofen PRN, Oral o Fever inflammatory, analgesic, and patients hypersensitive
o Juvenile arthritis anti-pyretic effects, possibly to drug and in those
Brand Name: by inhibiting prostaglandin with angio-edema,
Children’s Motrin synthesis. syndrome of nasal
polyps, or
Classification: bronchospastic reaction
Non-steroidal anti- to aspirin or other
inflammatory drugs NSAIDs.
o Contraindicated in
pregnant women.
o Use cautiously in
patients GI disorders,
history of peptic ulcer
disease, hepatic or
renal disease, cardiac
decompensation,
hypertension,
preexisting asthma, or
known intrinsic
coagulation defects
o Check renal and
nervousness, aseptic
minigitis
CV: peripheral edema, fluid
retention, edema
EENT: tinnitus
GI: epigastric distress,
nausea, occult blood loss,
peptic ulceration, diarrhea,
constipation, abdominal
pain, bloating, GI fullness,
dyspepsia, flatulence, heart
burn, decreased appetite
GU: acute renal failure,
azotemia, cystitis, hematuria
Hema to lo gic: prolonged
bleeding time, anemia,
neutroenia, pancytopenia,
thrombocytopenia, aplastic
anemia, leucopenia,
agranulocytosis
Meta bo lic: hypoglycemia,
hyperkalemia
Res pir ato ry :
bronchospasm
hepatic function
periodically in patients
on long-term therapy.
Stop drug if
abnormalities occur
and notify prescriber.
o Because of their
antipyretic and anti-
inflammatory actions,
NSAIDs may mask
signs and symptoms
of infection
o Blurred and
diminished vision and
changes in color vision
have occurred
o It may take 1 or 2
weeks before full anti-
inflammatory effects
occur
o Serious GI toxicity,
including peptic ulcers
and bleeding, in
patient taking NSAIDs,
despite lack of
symptoms
o If patient consumes
three or more
alcoholic drinks per
day, use of ibuprofen
may lead to stomach
bleeding
o Alert: don’t confuse
Trendar with Trandate
Source: Nursing 2005 Drug Handbook 25th Edition