TEST PAPER

Gastro Intestinal System & Disorders

Marks
50

Time 30 mins
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Q.1. Fill in the Blanks (Each blank carry one mark)

1. The movements that propel the food particles through the digestive
tract are called ___________________.
2. ___________ ulcer: Causes sharp pain in the stomach soon after eating
3 Gastroesophageal Reflux Disease (GERD) is also known as
________________.
4. Inflammation of the lining of stomach is called ___________________.
5. Most commonly used Antacids are _________________ and
_________________
salts.
6. _________________________ acts by blocking H+, K+ -ATPase enzyme
system .
7. _________________ agents increase both gastric emptying and lower
esophageal
sphincter pressure or tone .
8. Vomiting is also known as ________________ .
9. Domperidone inhibits __________________ receptors in CTZ and thus acts
as an
anti-emetic, and in the GIT works as a prokinetic.
10. Amoebiasis is caused by a parasite known as ___________________.
11. Passage of small amounts of hard, dry bowel movements (stools),
usually fewer

than three times a week is also known as __________________.

12. _____________________ are drugs which help in easing the passage of
stools.
13. Sites of Peptic ulcer are - ______________ Ulcer, _______ Ulcer and
___________________ Ulcer.
14. ___________________ is most preferred antibiotic for the treatment of
H.Pylori
infection.
15. The

parietal cells have 3 kinds of receptors on their surface :

_________________ receptor
_________________ receptor
_________________ receptor

Q.2 Write (True) in front of the True statement and (False) for the
False
Statement.
1. Liver, gall bladder, salivary glands and pancreas are minor accessory
organs.(
).
2. Three activities are involved in the digestive process: mechanical
digestion,
chemical digestion, and absorption. (
).
3. Since both H+ and Cl- ions are outside the cell, they can combine
together to form
HCl in the presence of H2O . (
).
4. Infection with H. pylori bacteria (i.e. H. pylori-associated ulcers-are rare
and are
reported to be overall just only 10% cases) (
).
5. Gastric ulcer is typically relieved by eating, or by drinking milk (
).
6. Helicobacter pylori produces gyrase enzyme that produces ammonia
(damages stomach tissues) (
).
7. Antacids reduce volume of HCl secreted. (

).

8. Emollient laxatives are best used to prevent constipation in people who

need to avoid straining e.g. after recent surgery. (
).
9. Irritation and inflammation of the digestive tract, commonly known as
food poisoning (
).
10. Irritable bowel syndrome (disease where patient has constipation
alternating with diarrhea) (
).
Q.3 Match the following :
A
1 First step of digestion
2. Mucous cell
3.
4.
5.
6.

Parietal cells
Intrinsic factor
CTZ
Hiatus Hernia

7. Odynophagia
8. Stool softeners
9. Osmotic Laxatives
10.Haematemesis
11.Melena
12.Overuse of laxatives

B
a. needed for absorption of vitamin
B12
b. Protrusion of the stomach above
Diaphragm
c. vomiting of blood
d. Docusate sodium
e. secretes alkaline mucus
f. 5HT3 & D2 receptors & is outside
BBB
g. pain during swallowing
h. secrete hydrochloric acid
i. black faeces containing blood
j. leads to inactive bowel
k. breaks down food into a fine pulp
l. magnesium hydroxide ,lactulose

Answers : (1 - ), (2 ),(3 ),(4 ),(5 (8),

(9 - ),(10 - ), (11 - ), (12 - ).

),(6 -

),(7-

),

Q.4. Choose the correct answer ( Please tick the right answer)
1. Chief cells are responsible for secretion of a. Mucus
b. Pepsinogen
c. Gastrin
d. Hydrochloric acid

2. Primary symptoms may be bloating, fullness & gas

distention of
abdomen in
a.
b.
c.
d.

Ulcer-like dyspepsia
Motility-like dyspepsia
Reflux-like dyspepsia
Functional or non-ulcer dyspepsia

3. Enterochromaffin -like cells or mast cells secretes a. Mucus

b. Acetylcholine
c. Gastrin
d. Histamine
Q 5. Explain the following terms (One mark each)
1. Dyspepsia :
_________________________________________________________________________
_________________________________________
2. Stimulant Laxatives :
________________________________________________________________________
____________________________________________________________
3. Short coming of H2 receptors Antagonists : (3 marks)

__________________________________________________________
__________________________________________________________
__________________________________________________________
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