Announcements 06

The American Association for Clinical Chemistry extends its sincere thanks to the following companies for their
generous support through their contributions.
Bio-Rad Laboratories Abbott Diagnostics

Registration Portfolios Hotel Keycards (selected hotels) Educational Sessions Workshop Refreshments
IVD Technology Magazine/ Canon Communications

International Marketing Seminar
Cardinal Health, Scientific Products Distribution ACON Laboratories, Inc.

Exhibitor Lanyards Past Presidents Award
Olympus America, Inc., Diagnostic Systems Group

Exhibit Hall Refreshment Breaks Lead Retrieval Cards Award for Outstanding Contributions in
Dade Behring, Inc.

Edwin F. Ullman Award for
Selected Area of Research
Technological Innovation Notepads and Pens
Bayer HealthCare, Diagnostics Division

AACC Lectureship Award Award for Outstanding Contributions
to Clinical Chemistry The Morton K. Schwartz Award for Significant Contributions in Cancer Research Diagnostics
Diagnostic Products Corporation

Sigi Ziering Award for Outstanding
Ortho-Clinical Diagnostics
Program and Exhibit Guides Award for Outstanding Clinical Laboratory
Contribution for a Publication in the Journal Clinical Chemistry
Contributions to Patient Safety
BD Diagnostics, Preanalytical Systems

International Travel Fellowship
Diagnostica Stago, Inc.

ClinPack Door Drop Bags (selected hotels)
Quest Diagnostics Hospital Services

Award for Outstanding Contributions
in Education
DiaSorin
Educational Session
Roche Diagnostics
Award for Outstanding Scientific
Beckman Coulter, Inc.

Award for Outstanding Contributions through
Achievements by a Young Investigator

As of June 2006
Service to the Profession of Clinical Chemistry
Fujirebio Diagnostics, Inc.

Attendee Lanyards
CLINICAL LABORATORY NEWS SPECIAL EDITION
2006 AACC AWARD WINNERS
Clinical Laboratory Science Leaders Receive Awards

At the opening plenary sessions of the 2006 AACC Annual Meeting, several eminent scientists were recognized for their outstanding achievements in the field of clinical laboratory science and their excellent contributions to the profession. AACC president John E. Sherwin, PhD, FACB, and representatives of the sponsoring companies presented the awards. AACC and CLN salute these leaders.
The AACC Lectureship Award
Sponsored by an educational grant from Bayer HealthCare Diagnostics Division 1995 (she was the first recipient). She is a fellow of the American Association for the Advancement of Science, the American Institute of Chemists, and the Royal Society of Chemistry. Dr. Al Free, her late husband of nearly 53 years, was also a Bayer chemist. Together, they are enshrined in the Science and Engineering Hall of Fame and the National Inventors Hall of Fame. lina, her responsibilities focus on service and education. She teaches a variety of UNC students, including undergraduates in the clinical laboratory science program, secondyear medical and dental students, graduate students, residents, and fellows. She often presents programs and lectures covering a range of laboratory topics to other healthcare providers, including clinicians, nurses, and clinical laboratory scientists. She is codirector of the University of North Carolina Hospitals postdoctoral training program in clinical chemistry. An AACC member since 1982, Dr. Hammett-Stabler has served on a number of committees, including the 2000 and 2003 Annual Meeting Organizing Committees. She chaired the editorial board of Clinical Chemistry News. She is past-chair of the TDM and Toxicology Division, where she has held many other positions as well. Dr. Hammett-Stabler serves on the board of directors of the American Board of Clinical Chemistry and the National Registry of Certified Chemists. She is a member of several editorial boards, including Clinica Chimica Acta and Therapeutics and Toxins, and is an associate editor of Clinical Biochemistry. tate specific antigen for the early detection and clinical management of prostate cancer. Recently, he helped to develop the assay for the circulating tumor cell and established its utility as a prognostic marker for patients with metastatic breast cancer. Dr. Fritsche participated in the clinical trials leading to Food and Drug Administration clearance of all of the serum tumor marker tests currently in use. His current work focuses on the role of circulating DNA as a tumor marker.
Harvey V. Fineberg, MD, PhD

Dr. Fineberg is president of the Institute of Medicine of the National Academy of Sciences in Washington, D.C. He served as provost of Harvard University from 1997 to 2001, following 13 years as dean of the Harvard School of Public Health. He has devoted most of his academic career to the fields of health policy and medical decision making. Dr. Fineberg helped found and served as president of the Society for Medical Decision Making and also served as adviser and consultant to the U.S. Centers for Disease Control and Prevention and the World Health Organization. At the Institute of Medicine, he has chaired and served on a number of panels dealing with health policy issues, ranging from AIDS to vaccine safety. He is the author, co-author, and co-editor of numerous books and articles on such diverse topics as AIDS prevention, tuberculosis control, assessment of new medical technology, clinical and public health decision making, and understanding risk in society.
Award for Outstanding Clinical Laboratory Contributions to Patient Safety

Sponsored by Ortho-Clinical Diagnostics
Michael L. Astion, MD, PhD

Dr. Astion is a clinical pathologist who is an associate professor and director of reference laboratory services at the University of Washington Department of Laboratory Medicine in Seattle. His career is equally divided between teaching, clinical service, and research and development. He has authored more than 20 software titles and more than 30 papers. His software includes both laboratory tutorials and competency assessment exams, and these materials are now used by more than 15,000 clinical laboratory workers each year. He is the editor-in-chief of Laboratory Errors and Patient Safety, a newsletter dedicated to improving laboratory quality. Dr. Astion is a frequent speaker at professional meetings, where he lectures on issues related to laboratory test interpretation, autoantibody testing, medical errors, medical informatics, and competency assessment. His previous awards include the American Society for Clinical Laboratory Sciences Theriot Award for Excellence in Media, which he received twice for his educational software. A frequent winner of the AACC outstanding speaker award, Dr. Astion has been active in AACC, including as a symposium organizer on the 2005 Annual Meeting Organizing Committee. He currently heads the AACC patient safety task force.
Award for Outstanding Contributions Through Service to the Profession of Clinical Chemistry
Sponsored by Beckman Coulter, Inc.
Gary L. Myers, PhD, FACB

Dr. Myers is chief of the clinical chemistry branch at the Centers for Disease Control and Prevention in Atlanta. He also serves as the scientific director of the World Health Organization Collaborating Center for Reference and Research in Blood Lipids at the CDC. His 30-year career at the CDC has focused on improving the laboratory measurement of biochemical markers used to assess chronic disease risk, particularly cardiovascular disease. As the CDCs representative on the National Cholesterol Education Programs Laboratory Standardization Panel, he played a pivotal role in developing national guidelines to improve the reliability of cholesterol testing. He organized the Cholesterol Reference Method Laboratory Network, which has been a model for other such efforts. Dr. Myers has served AACC at all levels. He is currently president-elect and recently completed a three-year term on the board of directors. He chaired the Lipids and Lipoproteins Division, which presented him the Gerald R. Cooper Award for Outstanding Service. He chaired the 2002 Annual Meeting Organizing Committee and the 2006 Beckman Conference. Dr. Myers has served on many AACC committees. He chairs the National Academy of Clinical Biochemistrys Committee for a Laboratory Medicine Practice Guideline for Emerging Cardiac Markers and is involved with various other national and international organizations dealing with laboratory measurement and standardization issues. He serves on the National Kidney Disease Education Programs Laboratory Working Group, the American Diabetes Associations Insulin Standardization Working Group, the International Federation of Clinical Chemistrys Working Group on Hemoglobin A1c Standardization, and the National Institutes of Healths C-peptide Standardization Committee. Dr. Myers also serves on the board of the Clinical and Laboratory Standards Institute and chairs its Global Advisory Committee. He has published more than 80 articles, book chapters, and editorials. See AACC Awards, continued on page 12
The Morton K. Schwartz Award for Significant Contributions in Cancer Research Diagnostics
Sponsored by Bayer Healthcare Diagnostics Division
Award for Outstanding Contributions To Clinical Chemistry

Sponsored by Bayer HealthCare Diagnostics Division
Herbert A. Fritsche, PhD, FACB

Dr. Fritsche has served as chief of clinical chemistry at M.D. Anderson Cancer Center in Houston for the past 37 years. He has served in all elected positions in AACCs Texas Section and chaired the national Education Committee and the Education Committee of the Immunology Division. He has served as president of the Clinical Ligand Assay Society and is a member of the editorial board of six journals. He has lectured at many international meetings and has published more than 150 papers and 30 book chapters in the field of cancer diagnostics. He is a member of the scientific advisory boards of six companies; holds four patents and two patent applications; is co-author of a recent textbook, Tumor Markers; and is the meeting director of a biennial conference on cancer diagnostics sponsored by M.D. Anderson. He has been active in the field of cancer diagnostics since 1969. He was one of the early proponents of the direct serum assay for carcinoembryonic antigen (CEA) for breast cancer monitoring. He was one of the first to develop immunonephelometric assays for serum immunoglobulins and to apply the beta-2 microglobulin assay for multiple myeloma, to implement the serum lactate dehydrogenase-1 assay as a complement to alpha-fetoprotein and human chorionic gonadotropin for monitoring patients with germ cell tumors, and to use serum pros-
Helen M. Free, DSc

Dr. Free has spent her entire scientific career of more than 60 years at Bayer Healthcare Diagnostics Division (formerly Miles Laboratories) in Elkhart, Ind., where she continues as a professional relations consultant in the diabetes care division. Her work has ranged from her start as a control chemist to senior new products manager of microbiological test systems to director of specialty test systems to director of marketing services. She has taught management at Indiana University at South Bend for 20 years. She has served AACC in many capacities, including two terms on the board of directors; as a member of the Professional Relations Commission, Nominating Committee, and Public Relations Committee; as chair of the Committee on Divisional Affairs and Chicago Section; and as president in 1990. She is a past president of the National Registry of Certified Chemists. Dr. Free is a 50-year member of the American Chemical Society (ACS), which she served as president in 1993. The ACS presented her its Garvan Medal for distinguished service to chemistry by a woman, and in her honor, instituted the Helen M. Free Award in Public Outreach in
Award for Outstanding Contributions in Education

Sponsored by Quest Diagnostics Nichols Institute
Catherine A. Hammett-Stabler, PhD, DABCC, FACB

Dr. Hammett-Stabler is director of the clinical toxicology, clinical pharmacology, and pediatric metabolism laboratories and associate director of the core laboratory of the McLendon Clinical Laboratories at the University of North Carolina Hospital in Chapel Hill. As an associate professor in the department of pathology and laboratory medicine at the University of North Caro-
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AACC Awards, continued from page 10 Award for Outstanding Contributions In a Selected Area of Research
Sponsored by Olympus America Inc., Diagnostic Systems Group
Hugo Katus, MD
Dr. Katus is chief of internal medicine and director of the cardiovascular medicine department of the University of Heidelberg in Germany. He is president-elect of the Academy of Cardiology of the German Society of Cardiology and editor of Clinical Research in Cardiology (formerly Zeitschrift fr Kardiologie), the official journal of the German Cardiac Society. After years of work in the field, in 1984 he was the first to develop a cardiac-specific troponin assay that demonstrated in initial clinical trials the superior performance of this marker in patients with suspected myocardial infarction. In cooperation with Boehringer Mannheim (now Roche Diagnostics), he improved the analytical performance of the troponin T assay to make it useful for large-scale clinical chemistry testing. He holds with Roche Diagnostics an international patent on the troponin T assay. In cooperation with clinical partners, he then showed the superior performance of the troponin T assay in large randomized multi-center trials. These results documented for the first time the clinical significance of minor myocardial injury, which had remained undetected by CK-MB isoenzyme analyses. This work has markedly affected the diagnostic approaches in suspected myocardial injury and led to a new definition of myocardial infarction, which is now based on a troponin standard. Troponin measurements have also proven useful for diagnosis and risk stratification in various other disorders, such as myocarditis, heart failure, end-stage renal disease, and pulmonary embolism. In recent years, Dr. Katuss scientific interests have shifted to the genetic basis of cardiomyopathies and heart failure. He now serves as coordinator of the cardiovascular genomic research initiative of the German Ministry of Science.
used to detect alkaline phosphatase labels and other hydrolytic enzymes. He has also played an important role in adapting chemiluminescent and bioluminescent assays to point-of-care testing. His second defining work, in collaboration with Dr. Peter Wilding, is with analytical microchips. Dr. Kricka played a critical role in the development of micro-fabricated clinical analysis devices and devices that isolate cells, analyze DNA, test for fertility, assist in vitro fertilization, test for drugs and hormones, and integrate tests for malignancy. These miniaturization techniques resulted in the first demonstration of numerous analytically useful processes in microchips, including immunoassay, assessment of sperm motility, and DNA amplification. Today many laboratories and companies have research and development programs based on Dr. Krickas discoveries. Dr. Kricka holds 30 U.S. patents and is the author or co-author of over 350 articles, abstracts, book chapters, and papers, and of 20 books. He is editor-in-chief of Luminescence; a member of the editorial boards of Clinical Chemistry, Lab-on-a-chip, and Analytical Biochemistry; and past editor of the Journal of Immunoassay.
ing his educational and research activities to promote clinical chemistry in Istanbul, Turkey, and Oslo, Norway.
The Sigi Ziering Award for Outstanding Contribution for a Publication in the Journal Clinical Chemistry
Sponsored by Diagnostic Products Corporation (DPC)
David J. Warren, PhD

Dr. Warren is a senior scientist in the central laboratory at the Norwegian Radium Hospital in Oslo. During his postdoctoral research at Memorial SloanKettering Cancer Center, he worked with a group that demonstrated that a neutrophil differentiation factor (GCSF) therapy ameliorated the neutropenia associated with cytotoxic chemotherapy and accelerated neutrophil recovery following bone marrow transplantation. This growth factor is now in extensive clinical use. Dr. Warrens research also helped to elucidate the role played by G-CSF in the pathology and therapy of a variety of inherited neutropenic states including cyclic hematopoiesis and congenital agranulocytopenias. As a visiting scientist at the University of Bergen in Norway, Dr. Warren developed a number of new assays, including a unique method for the determination of the levels of cytotoxic nucleotide accumulation into the leukocyte DNA of acute lymphocytic leukemia patients receiving 6-mercaptopurine maintenance therapy. Subsequent projects on drug metabolism led him to establish methodologies for the efficient expression of recombinant proteins. His current research interests include the development of single-chain antibodies as reagents in immunometric assays for tumor marker antigens and the characterization of the extracellular domain of the ovarian marker CA125. His winning article, Use of an In Vivo Biotinylated Single-Chain Antibody as Capture Reagent in an Immunometric Assay to Decrease the Incidence of Interference from Heterophilic Antibodies, describes an elegant new approach to eliminate common inferences in immunometric methods, which if successfully implemented could produce more accurate results in these widely used tests. The papers co-authors were Johan Bjerner, Elisabeth Paus, Ole P. Brmer, and Kjell Nusad.
International Travel Fellowship

Sponsored by BD Diagnostics Preanalytical Systems
the Clinical Chemistry Board of Editors, as well as chair of the Membership Committee and the Division Management Group. Under his leadership, 2005 was an exciting and busy year for AACC, as he pursued twin major goals of increasing the number of young scientists entering the field and increasing clinician awareness of AACC and laboratory medicine. The Society for Young Clinical Laboratorians speaker series began recruiting graduate students into the field of laboratory medicine, and this effort is paying off with new trainees and an increased number of postdoctoral training programs. An initiative to increase interactions with clinical societies led to AACC members presenting at meetings of societies such as the American Diabetes Association and the American Association of Clinical Endocrinologists. The National Academy of Clinical Biochemistry and AACC completed negotiations that led to the successful merger of NACB into AACC, which will truly make the NACB the Academy of AACC and a place to honor members with distinguished academic careers. Progress on numerous other association efforts continued as well, including publication of all of the back issues of Clinical Chemistry from 1954 through 1996 on the Web site and initiation of a proteomics conference by the new Proteomics Division.
Sarfraz Ahmad, PhD

Dr. Ahmad is chief research scientist and research manager at the Florida Hospital Cancer Institute in Orlando. Before joining that institution in 2002, he spent ten years in research and teaching at Loyola University of Chicago and the University of Illinois at Chicagos department of medicine. Dr. Ahmads research and teaching interests include cellular and molecular hemostasis, thrombosis, and cancer biology, particularly related to the pathogenic mechanisms in immune disorders such as heparin-induced thrombocytopenia. His investigations are also aimed toward the development of novel anticoagulant, antithrombin, antiplatelet, and thrombolytic drugs for the management of cardiovascular/hematological patients. His past research interests focused on protein/enzyme purification and characterization, lectinglycoprotein interactions, pathophysiology and signaling mechanisms in sepsis/shock syndrome, interferon/cytokine-mediated tyrosine phosphorylation in hematopoietic cells, immune response in T-cell signaling, and skeletal muscle metabolism research. In these various areas of research, Dr. Ahmad has published 80 articles and book chapters and more than 200 abstracts. He is a reviewer for several biomedical journals and has received numerous awards for his research contributions. Dr. Ahmad is an active member of several national and international scientific societies, and has been an executive committee member of the Association of Scientists of Indian Origin in America (ASIOA) for more than a decade. He has traveled worldwide as a speaker at various national and international platforms. In addition to his ties to U.S. institutions, he has maintained international research collaborations with Danish, German, Indian, Italian, and Turkish biomedical institutions. He plans to use this International Travel Fellowship Award dur-
Award for Outstanding Scientific Achievements by a Young Investigator

Sponsored by Roche Diagnostics
Roshini S. Abraham, PhD

Dr. Abraham is an assistant professor of medicine and laboratory medicine and pathology at the Mayo College of Medicine and co-director of the clinical immunology laboratory (where she is director of the cellular and molecular immunology section) at the Mayo Clinic in Rochester, Minn. During her postdoctoral fellowship at the Mayo Clinic, she investigated the immunogenetic mechanisms that contribute to the pathophysiology of systemic lupus erythematosus and Type 1 diabetes in human leukocyte antigen (HLA) transgenic animal models as the principal investigator on two grants. She then joined the faculty, with a research focus on B cell clonal evolution and differentiation in the pathogenesis of immunoglobulin light chain amyloidosis, a bone marrow plasma cell dyscrasia. She was also actively involved in the clinical immunology laboratory in the dysproteinemia area. Her current clinical laboratory and research interests are in the area of laboratory diagnosis of primary immunodeficiencies and the assessment of immune competence, function, and reconstitution in a variety of clinical settings, including solid organ transplantation, hematopoietic stem cell transplantation, immunotherapy, and cancer vaccines. She is also involved in teaching clinical immunology to graduate students, pathology residents, clinical chemistry fellows, and allied laboratory health staff. Together with many collaborators and trainees, she has authored 25 peer-reviewed papers and 21 abstracts. She is a manuscript reviewer for Clinical Immunology and the Journal of Allergy and Clinical Immunology. She received the 2003 George Grannis Young Investigator Award from the National Academy of Clinical Biochemistry CLN (NACB).
The Edwin F. Ullman Award

Sponsored by Dade Behring, Inc.
Larry J. Kricka, PhD

Dr. Kricka is professor of pathology and laboratory medicine at the University of Pennsylvania and director of the general chemistry laboratory at the Hospital of the University of Pennsylvania in Philadelphia. He has served AACC in countless capacities, the foremost as president in 2001. This award recognizes an individual for contributions that advance the technology of clinical laboratory sciences, and two of Dr. Krickas efforts, in particular, have had a profound effect on the field. The first involves chemiluminescence and bioluminescence: He was instrumental in the development of two of the three major chemiluminescent technologies currently used in routine testing, including an enhanced luminescence system for peroxidase labels and the 1,2-dioxetane substrate, now widely
The AACC Past Presidents Award

Sponsored by Cardinal Health, Scientific Products Distribution
Mitchell G. Scott, PhD, DABCC, FACB

Dr. Scott is co-medical director of clinical chemistry and decentralized testing at Barnes-Jewish Hospital and professor in the division of laboratory medicine, in the department of pathology and immunology at Washington University in St. Louis. He is co-director of the clinical chemistry postdoctoral training program at Washington University, where he has helped train more than 50 fellows and 100 residents. He has served AACC in many capacities, including on the Program Coordinating Commission, Meetings Management Group, and executive committee of
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The NACB 2006 Award Winners Praising the Achievements of Laboratory Leaders
Through its annual awards program, NACB, the Academy of AACC, celebrates the achievements of colleagues who have made significant contributions through scholarship and service to the profession. Chaired by Dr. Elizabeth Frank, the NACB Awards Committee wishes to thank the sponsors of these awards and to congratulate the 2006 Academy award winners.
NACB DISTINGUISHED SCIENTIST AWARD approach of non-invasive prenatal diagnosis. Directors, Commission for Educational and ization of gene dosage mutations in genetic
For Outstanding Research Advances In the Field of Clinical Biochemistry
Sponsored by Dade Behring, Inc. He has also applied this strategy to the detection of cancers which are common in Hong Kong, including nasopharyngeal cancer and liver cancer. Scientific Affairs (Chair), AACC Press Board of Editors, Commission on Publications (Chair), Delta Project, Governance Implementation Task Force, Program Coordinating Commission, and the Public Relations Program (Chair, HI5). He is a member and past newsletter editor of the Pediatric and Maternal-Fetal Division. Dr. Sherwin is also a Past-President of the National Academy of Clinical Biochemistry, a member of the NACB Finance Committee, and has served on the Publications and Nominating Committee. He has served twice on the NACB Board of Directors.
Y. M. Dennis Lo, MD
Professor Dennis Lo received his preclinical medical training from the University of Cambridge. He then moved to Oxford University where he pursued his clinical medical training. Following qualification, he further obtained his Doctor of Philosophy and Doctor of Medicine degrees from Oxford. Dennis Lo began his academic career in Oxford as a Junior Research Fellow in Natural Sciences at Herford College, following by appointments to the University Lectureship in Clinical Biochemistry and a Fellowship at Green College. Dr. Lo was an Honorary Consultant Chemical Pathologist at the John Radcliffe Hospital, the main teaching hospital of Oxford Medical School. He returned to Hong Kong in 1997 and joined The Chinese University of Hong Kong (CUHK). Dr. Lo is the Associate Dean (Research) and the Dr. Li Ka Shing Professor of Medicine and Professor of Chemical Pathology of the Faculty of Medicine of CUHK. He has also been recently appointed as the Director of the new Li Ka Shing Institute of Health Sciences. Dr. Los main research interest is the study of cell-free DNA and RNA molecules which exist in the plasma of human subjects. He discovered in 1997 that an unborn fetus will release its DNA into the plasma of a pregnant woman. This finding has opened up a new
NACB ALVIN DUBIN AWARD

For Outstanding Contributions To the Profession and the Academy Sponsored by Abbott Diagnostics
John E. Sherwin, PhD, DABCC, FACB

JohnSherwin,PhD,DABCC, FACB is Chief, Genetic Disease Laboratory of the California Department of Health Services. He earned degrees at the University of Arizona, Tucson, and the University of California, Santa Barbara, and did postdoctoral training with Dr. Masaki Furuya at the University of Tokyo and Dr. Samuel Natelson at Michael Reese Hospital in Chicago. He has held positions as hospital laboratory director, senior technical director, general manager, and chief operating officer of multimillion-dollar reference laboratories, and a consultant to physicians and the diagnostics industry. Dr. Sherwin is President of AACC and has served the Association in a variety of capacities including local section offices, Educational Resources Committee, Committee on Pediatric Clinical Chemistry, Committee on Education, Annual Meeting Organizing Committee Co-Chair Selected Topics, Symposium Committee, House of Representatives, Council Steering Committee, Board of
N A C B G E O R G E G R A N N IS AWARD
For Outstanding Scientific or Clinical Report Sponsored by NACB with support from the AACC Ohio Valley Section
Linnea M. Baudhuin, PhD

Linnea M. Baudhuin received her PhD in Clinical Chemistry from Cleveland State University, in conjunction with the Cleveland Clinic Foundation, in Cleveland, Ohio in 2002. Her graduate research projects were focused on the characterization and identification of molecular markers and signaling pathways of lysolipids in ovarian cancer. After completing her graduate studies, Dr. Baudhuin joined the Mayo Clinic in Rochester, Minn. as a post-doctoral fellow in Clinical Chemistry and Clinical Molecular Genetics. Here, Dr. Baudhuin expanded her research interests to include novel risk markers for cardiovascular disease, molecular character-
disease, and development of clinical molecular genetic testing algorithms for hereditary colorectal cancer. Dr. Baudhuin joined the staff of the Mayo Clinic in 2005 as Assistant Professor of Laboratory Medicine within the Mayo Clinic College of Medicine and codirector of both Cardiovascular Laboratory Medicine and the Nucleotide Polymorphism Laboratory in the Department of Laboratory Medicine and Pathology. Her current research interests include pharmacogenetics, molecular markers for cardiovascular and endocrine disease, and clinical cardiovascular molecular genetics. Dr. Baudhuin has published 16 peerreviewed articles in journals such as the Journal of Molecular Diagnostics, Gastroenterology, FASEB Journal, and Clinical Biochemistry as well as a book chapter in the Handbook of Cell Signaling. Dr. Baudhuin has been the recipient of several awards, including the 2004 Richard Marshall Education Award given by the Midwest Section of the AACC, the 2001 Young Investigator in Breast Cancer Research Award and the 2001 Graduate Student Award in Research both from the Cleveland Clinic Foundation, and honorable mention at the 2001 AACC Student Poster Contest. She is currently Chair of AACCs Society for Young Clinical Laboratorians and a diplomate of the American Board of Medical CLN Genetics, Clinical Molecular Genetics.
Stop by the AACC Booth
for the latest info on all our educational programs.
#2051
NACB Honors New Academy Fellows

The National Academy of Clinical Biochemistry (NACB) is proud to announce the following new Academy Fellows. As NACB members these distinguished scientists are all doctorate-level professionals dedicated to enhancing the scholarship and practice of clinical biochemistry. New Fellows will be honored during the NACB awards luncheon on Wednesday, July 26. The official Academy of AACC, NACB honors the achievements of its members, and through an active education and publication program, enlists their support and expertise to bring about positive change in the current practice of clinical biochemistry. To learn more about the Academy and its activities, stop by the NACB desk in the AACC Booth (2051) or visit NACBs Web site at www.nacb.org. New NACB Fellows Tito Bacarese-Hamilton, PhD Loring Bjornson, PhD Bonny Bukaveckas, PhD David Bullock, PhD Leslie Burnett, MD, PhD Olukayode Dada, PhD Mary Lou Gantzer, PhD Amit Ghoshal, PhD Sorin Giju, PhD
Accepted since summer 2005.
Harold Harrison, MD, PhD That Ngo, PhD Maurice Owen, PhD Richard Pang, PhD Jagannadha Peela, MD Gurbuz Polat, MD Lori Sokoll, PhD Andrea Terrell, PhD Young Wang, MD
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At AACC, we appreciate and value the dedication of our members and member volunteers who have significantly contributed to AACCs growth and success over the decades. We are pleased to recognize members celebrating their 25 and 50 year anniversaries of continuous membership.
25 YEAR MEMBERS
Victor A. Hruszczyk Judith Huse Jean-Fritz Jean-Baptiste Stanley C. Kammerer Thais Edwina Keegan David W. Kinniburgh Henrietta L. Kohn Mitchell Scott Laks Dennis E. Leavelle Douglas E. Lewis Frank Ju-feng Liu Ronald G. Markevitch Samuel E. Mathews Gina Micci Alvine Mills Michel H. Miron Pei-Sheng Mo David L Morris Albert R. Nazareth James Nielsen Stephen Noel Jose Maria Olivella Navarro Barnabas H. Pataky Linda S. Pellegrino
Penny I. Peng Susan E. Puskas Roberta G. Reed Nader Rifai Joe C. Rutledge Ron B. Schifman Frederick Alexandre Smith Colen Bruce Smith Wolfgang Stein Galen G. Stickney W. Allen Taylor James L. Wittliff Thomas E. Worthy Randall W. Yatscoff Jack Zakowski
50 YEAR MEMBERS
Akira Abe G. Robert Ainslie Marilyn K. Barreca Dennis Mark Bleile William Z. Borer Sheila Carol Boss Jean-Pierre Braun Michael D. Burke Georges Chong David Chou Norman B. Coffman Robert J. Cornette Richard A. Cox Joyce P. De Maio Robert Farnham William F. Fitter Valerio M. Genta Barbara J. Gillian Frans K. Gorus Christine Grudzien Patricia A. Harper Edward D. Helton Richard Hoffman
Samuel Frankel S. Lawrence Jacobs Gerald Kessler Stanley Towers Lane Theodore Peters
As of 4/22/2006
We are grateful to ALL our members, who through their worldwide leadership and dedication to the profession, continue to make AACC the premier organization for clinical laboratory scientists.
AACC Divisions Recognize Contributions to Laboratory Medicine

AACCs divisions routinely recognize the achievements and contributions of their colleagues through awards and travel grants. Congratulations to these award winners for 2006.
A NIMAL C LINICAL C HEMISTRY D IVISION Award for Outstanding Contributions To Animal Clinical Chemistry Sponsored by Bayer Diagnostics Recipient: Douglas J. Weiss, DUM, PhD, University of Minnesota, St. Paul, Minn. C LINICAL & D IAGNOSTIC I MMUNOLOGY D IVISION International Travel Grant Recipient: Dilshad Ahmad Khan Army Medical College, Wah, Pakistan therapy on the activated clotting time. Recipient: S. El Rouby
Research Grant Recipient Role of alcohol induced liver damage on the regulation of vessel maturation. Recipient: Subir Kuman Das, PhD
H ISTORY D IVISION Sam Meites Award for Enhancing Our Knowledge of the History Of Clinical Chemistry Recipient: Louis Rosenfeld, PhD Brooklyn, N.Y. I NDUSTRY D IVISION Industry Division Service Award Recipient: To be announced
International Travel Grant Recipient: Dragana Begovic, KBC, Dr. Dragisa Misovic, Belgrade, Serbia & Montenegro Outstanding Article in Fats of Life Newsletter Recipient: Jose Ordovas for Gene-Diet Interactions, Blood Lipids, and Cardiovascular Disease Risk: The Rise of Nutrigenetics. Summer 2005, Fats of Life. Poster Award Winners Three awards are given for outstanding abstracts accepted at the AACC Annual Meeting in the area of lipoproteins and vascular diseases. Recipients are announced in Fats of Life.
M ANAGEMENT S CIENCES D IVISION Award for Outstanding Contributions to Management Sciences Recipient: Carl Garber, PhD, Quest Diagnostics, Lyndhurst, N.J.
Simultaneous determination of seven N-acetyltransferase -2 polymorphisms by allele-specifc primer extension assay. Recipient: Ysheng Zhu
International Travel Grant Recipient: Sorin Giju Clinical Country Hospital Timisoara, Romania Outstanding Research in Clinical and Diagnostic Immunology Reducing autoantibody interference in thyroglobulin testing. Recipient: Andrew Hoofnagle, MD, PhD University of Washington, Seattle, Wash.
C RITICAL AND P OINT - OF -C ARE T ESTING D IVISION Point-of-Care Coordinator of the Year Recipient: Edwina F. Szelag Holmes Regional Medical Center Health First, Inc, Melbourne, Fla.
Young Investigator Award for Outstanding Research in Molecular Pathology or Pharmacogenomics Correlation of venous and capillary trough and C-2 cyclosporin A concentrations by ILC/MS/MS with CYP3A4* and CYP3A5*3 geotypes in transplant patients. Recipient: Paul Janetto, PhD
N UTRITION D IVISION Gary Labbe Award for Contributions to Laboratory Assessment of Nutritional Status Recipient: To be announced. P EDIATRIC & M ATERNAL -F ETAL D IVISION Award for Outstanding Contributions to Pediatric and Maternal-Fetal Clinical Chemistry Recipient: George Brotea, PhD Ortho-Clinical Diagnostics, Inc., Rochester, N.Y. T HERAPEUTIC D RUG M ONITORING & C LINICAL T OXICOLOGY D IVISION TDM/Toxicology Young Investigator Award Recipient: To be announced.
Best Abstract of Interest To the Industry Division Recipient: To be announced.

L IPOPROTEINS AND V ASCULAR D ISEASES D IVISION Cooper Award for Outstanding Contributions to Service in the Area of Lipoproteins and Vascular Diseases Recipient: G. Russell Warnick Berkeley Heart Lab, Alameda, Calif.
International Travel Grant Recipient: Shivananda Nayak, Eric Williams Medical Science Complex, Mount Hope, Trinidad & Tobago.
M OLECULAR P ATHOLOGY D IVISION Outstanding Research in the Area of Molecular Pathology Or Pharmacogenomics
Abstract Award Winners Outstanding Research in Critical Care or Point-of-Care Testing The influence of prior oral anticoagulation
Pacific Biometrics Research Foundation Award for Contributions to the Technology of Clinical Chemistry Recipient: To be announced.
VA N S LY K E F O U N D AT I O N ( V S F ) 2 0 0 5 H O N O R R O L L
We would like to recognize contributors who have made donations totaling $100 or more from January 1, 2005, through March 31, 2006. We also thank all of the donors to the VSF who have helped to fulfill our mission to advance clinical laboratory medicine worldwide. For a current donor list, please go to http://www.aacc.org/vsf/honor_roll.stm.
CORPORATE MEMBERS Leaders ($100,000 and more) Roche Diagnostics Ortho Diagnostics Systems Johnson & Johnson Abbott Diagnostics Patrons ($25,000 to $49,999) Beckman Coulter Contributors ($10,000 to $24,999) Washington University of St. Louis Subscribers ($5,000 to $9,999) International Federation of Clinical Chemistry Diagnostic Products Corporation Donors ($100 to $4,999) Protedyne Corporation AACC LOCAL SECTIONS & DIVISIONS Sponsors ($10,000 to $49,999) TDM & Clinical Toxicology Division Lipoproteins and Vascular Diseases Division Sustainers ($5,000 to $9,999) Rocky Mountain Local Section Management Sciences Division Patrons ($1,000 to $4,999) Capital Local Section Immunology Division Michigan Local Section Molecular Pathology Division Pacific Northwest Local Section Southern California Local Section Contributors ($100 to $999) Southeast Local Section INDIVIDUAL MEMBERS Leaders ($100,000 and more) Gopal Savjani Gerald and Sandy Gallwas Sponsors ($10,000 to $49,999) Jocelyn Hicks Richard Nadeau Bernard Brody Kerri Weinert Richard Flaherty Robert Habig Sustainers ($5,000 to $9,999) Mary Lou Gantzer Laurence Demers Robert Stout Patrons ($1,000 to $4,999) Henry Diederichs Charles Galanaugh James Lo William Ottinger Bret Wien Mitchell Scott Jan Krouwer Bryce Cunningham Thomas Moyer John Sherwin Frederick Brazda Ann Gronowski Salvador Sena Ellis Jacobs Susan Evans Anthony Okorodudu Mathias Mueller Basil Doumas E. Freund Jack Tomas Shirley Welch Julius Kerkay Roger Calam Roger Bertholf William Luft D. Robert Dufour Donald Powers Cipriano Cipriani Nathan Gochman Tsan Liu Carl Garber Sara Michelmore Steven Wong Sam Berkman Fred Apple Masashi Itano Alan Runck Marion Mixson Contributors ($100 to $999) Donald Cannon Jane Schwartz Jean Joseph Harold Brown Kathleen Croes Scott Wilkin Sidney Tam John Mason Clara Sumeghy Vijaykant Kambli Christine Papadea Susan Gross Theodore Mifflin Katherine Chen James Ritchie Olive Wolfe Carlotta Eisen Peter Tsivis Kathleen Quill Geza Balas Zheng Zeng Jean Rhame Earl Soules Daniel Farkas Ruth McNair Thomas Yeung Enno Logemann Barbara Cooper Anthony Girgenti Harold Choitz Helen Churella Barry Dowell Stuart Dubin William Feldman Richard Lent Thomas Liddy Howard Ludwick Douglas Stickle Nathan Radin Harold Williams Fumio Yoshino Cheong Ngoi Jesse Goodwin Robert Johnson Mark Meyerhoff Irwin Oreskes Eugene Garcia Sarah Mook John Russo Terry Shirey Edward Ashwood Harald Drews Dalamaga Androniki Luciano Marchetti Samuel Mathews Harvey Kaufman Phyllis Feinblum Spohia Kakari Charles Hawker Jean Travers Wendy Sakano Ching-Nan Ou Sally Hojvat Michael Bennett Toshifumi Niwa Larry Broussard Special Gifts The Foundation extends special thanks to Mr. Gopal Savjani whose generous donation enabled the creation the Past Presidents Scholarship program. For further information about this new educational opportunity go to www. aacc.org/vsf/past_pres_scholarship.stm. The VSF also thanks Jerry and Sandy Gallwas for their generous gifts, which fund multi-year AACC memberships for deserving scientists from emerging areas of the world to provide them with access to AACC program and services, see www.aacc.org/ia/gallwas.stm. Planned Gifts The VSF gratefully acknowledges the following generous bequests from the following donors: Earl J. Scherago Betty K. Smith Contributions were made in memory of: Andrew Maturen, PhD Donald Soules, PhD Henry Weinert, PhD Donald Senn, PhD
16
Clinical Laboratory News

EDITORIAL STAFF EditorNancy Sasavage, PhD Senior EditorsJulie McDowell and
PLENARY SPEAKER SPOTLIGHT
William R. Clarke, MD
The Convergence of Diagnostics and the Transformation of Medicine

Wednesday, July 26, 8:4510:15 a.m. Current Position: Executive Vice President, Chief Medical and Technology Officer, GE Healthcare (Waukesha, Wis.) Education: Duke University, Durham, N.C.MD, MS, 1979; BA, 1974. Previous Positions: Executive Vice President, Research and Development, Amersham Health; Director of Biological Sciences, Glaxo Wellcome U.K.; Associate Professor, Department of Anesthesiology/Critical Care Medicine and Pediatrics, University of Washington School of Medicine.
a staff of 925 and administered an annual budget in excess of $145 million. His multinational R&D division supervised all aspects of pharmaceutical discovery, development, registration, and post-market support for Amersham. Clarke was Amershams lead spokesperson in multiple forums that addressed the impact of the new generation of molecular diagnostics on medical practice. Prior to his tenure at Amersham, Clarke spent three years as Director of Biological Sciences at Glaxo Wellcome U.K. (Uxbridge, U.K.), with responsibility for pre-clinical disease-focused biological research. He also chaired the Glaxo Wellcome Global Imaging Strategy Committee, which formulated corporate strategy and developed partnerships between industry and government. Before his time in industry, Clarke spent more than fifteen years in the academic world as a practicing academic physician with a specialty in pediatric critical care and pediatric anesthesiology. He also has research interests in pulmonary pharmacology and genetics. Clarkes most recent academic appointment was as Associate Professor in the Departments of Anesthesiology/Critical Care Medicine and Pediatrics at the University of Washington School of Medicine. Clarke received his BA in Chemistry, MS in Physiology and Pharmacology, and MD from Duke University (Durham, N.C.). He was also educated at the University of Washington School of Medicine, the University of Pennsylvania, and the Stockholm School of Economics. In his plenary lecture, Clarke will explain the role that molecular in vitro diagnostics play in directing clinicians towards the effective use of highly specific in vivo molecular imaging diagnostics. He will also highlight the convergence of in vivo and in vitro diagnostics with new targeted therapies in relevant CLN clinical disciplines such as oncology.
Richard Pizzi
Managing EditorBill Malone ContributorGeorge Linzer BUSINESS STAFF V.P. Marketing ProgramsJerry Goldsmith Circulation ManagerMickie Napoleoni BOARD OF EDITORS ChairSteve Manzella, PhD, York Hospital, Wednesdays Plenary Speaker, William R. Clarke, MD
York, Pa.
MembersJanine M. Cisek, MT(ASCP),
St. Lukes Hospital, Kansas City, Mo. Thomas Daly, MD, Eli Lilly and Company, Indianapolis, Ind. David Grenache, PhD, University of North Carolina at Chapel Hill, Chapel Hill, N.C. Jack A. Maggiore, PhD, BioSafe Laboratories, Chicago, Ill. Alan T. Remaley, MD, PhD, National Institutes of Health, Bethesda, Md.
AACC OFFICERS PresidentJohn E. Sherwin, PhD President-ElectGary L. Myers, PhD TreasurerLarry A. Broussard, PhD SecretaryRobert L. Murray, JDS, PhD Past-PresidentMitchell G. Scott, PhD ADVERTISING SALES
Emphasizing Molecular Diagnostics And Disease Prevention

In his current position as Executive Vice President at GE Healthcare (Waukesha, Wis.), William R. Clarke, MD, oversees a global technology and medical innovation portfolio with an average annual budget of approximately $1 billion. He also directs medical and regulatory strategy and policy for GE Healthcare and sits on the companys Executive Committee. Diagnostic technologies are at the center of GE Healthcares new early health model of care, which focuses on earlier diagnosis, pre-symptomatic disease detection, and disease prevention, and that makes Clarke ideally suited to convey the importance of molecular diagnostics to the future of medical care. Before joining GE Healthcare in April 2004, Clarke was the head of Global Research and Development at Amersham Health (Buckinghamshire, U.K.), where he managed
Scherago International, Inc. 525 Washington Blvd., Suite 3310 Jersey City, NJ 07310. Phone: (201) 653-4777. Fax: (201) 653-5705. E-mail: aacc@scherago.com.
PresidentH.L. Burklund Vice President SalesJack Ryan Marketing DirectorSteven A. Hamburger Trafc ManagerOlga Guerra SUBSCRIPTIONS
American Association for Clinical Chemistry, Inc. 1850 K Street, NW, Suite 625, Washington, DC 20006. Phone: (202) 857-0717 or (800) 892-1400. Fax: (202) 887-5093. E-mail: custserv@aacc.org. Subscriptions to Clinical Laboratory News are free to qualied laboratory professionals in the United States. AACC members outside the U.S. pay $60 for postage. The subscription price for those who do not qualify for a free subscription is $60/year in the U.S. and $95/year outside the U.S. Back issues may be ordered for $10 as available. For more information, contact the AACC Customer Service Department at (800) 892-1400 or (202) 857-0717 or custserv@aacc.org.
EDITORIAL CORRESPONDENCE
Mitochondria: The Missing Link Among Degenerative Diseases, Cancer and Aging, and the Next Molecular Diagnostics Frontier
Thursday, July 27, 12:302:00 p.m. Current Position: Donald Bren Professor of Molecular Genetics, Department of Ecology and Evolutionary Biology, University of California, Irvine (UCI); Director, Center for Molecular & Mitochondrial Medicine and Genetics (MAMMAG), UCI. Education: Yale UniversityPhD, 1975. Previous Positions: Robert W. Woodruff Professor of Molecular Genetics and Director of the Center for Molecular Medicine, Emory University; Professor of Genetics, Stanford University School of Medicine.
may be the key to the degenerative aspects of aging. In studying mitochondrial genetic evolution, Wallaces research group used mtDNA variation to reconstruct the origins and ancient migrations of women, and determined that all mtDNA lineages trace back to a single African origin some 200,000 years ago. His mitochondrial Eve theory has been a foundation of the new field of molecular anthropology and is hailed as a significant achievement in paleoanthropology. And there are other practical applications for Wallaces work still on the horizon. Medications currently under development in his MAMMAG labcalled catalytic antioxidantsmay someday help mitigate damage done to the mitochondria when mtDNA mutations accumulate. A member of the National Academy of Sciences, in 1994 Wallace received the William Allan Award, the American Society of Human Genetics highest recognition for contributions to human genetics. He also shared the Passano Award 2000 for mitochondrial genetics and received the 2000 Metropolitan Life Foundation Research Award for Medical Research in Alzheimers Disease. Wallaces mitochondrial research has fostered the exploration of the relationship between human evolution and some of the most common and disabling diseases. In his plenary lecture, Wallace will explain how the degenerative effects of aging may largely be fueled by accumulated mitochondrial mutations and the resulting malfunction of organs and systems throughout the body. He will also illustrate how many mtDNA malfunctions have their roots in evolutionary adaptations hidden in the history of the human species, and describe the ways in which mitochondrial research can lead to further CLN understanding of major diseases.
Douglas C. Wallace, PhD
Thursdays Plenary Speaker, Douglas C. Wallace, PhD
A Founder of Mitochondrial Genetics

One of the worlds leading scientists whose work ranges from tracing the origins of the human species to finding the causes of degenerative diseases, cancer and aging, Douglas Wallace, PhD, is one of the founders of the field of human mitochondrial genetics. Currently the Donald Bren Professor of Molecular Genetics at the University of California, Irvine, and director of the universitys Center for Molecular and Mitochondrial Medicine and Genetics (MAMMAG), Wallaces pioneering research has bridged the fields of microbiology, human genetics, medicine, and anthropology. In the early 1970s, Wallace demonstrated that mitochondrial DNA (mtDNA) mutations can cause certain forms of diabetes, cardiac and muscle disease, blindness, deafness, seizures, movement disorders, and dementias. He has shown that mtDNA mutations accumulate in our tissues with age, and thus
Nancy Sasavage, PhD, Editor Clinical Laboratory News, 1850 K Street, NW, Suite 625, Washington, DC 20006. Phone: (202) 857-0717 or (800) 892-1400. Fax: (202) 835-8725. E-mail: nsasavage@aacc.org. Contents copyright 2006 by the American Association for Clinical Chemistry, Inc., except as noted. Printed in the U.S.A.
Clinical Laboratory News (ISSN 0161-9640) is the authoritative source for timely analysis of issues and trends affecting clinical laboratories, clinical laboratorians, and the practice of clinical laboratory science.
2006 ANNUAL MEETING
Welcome to the 2006 Clinical Laboratory Exposition

July 25-27, 2006 Chicago, IL
AACC and ASCLS welcome you to the 2006 Clinical Lab Expo. Once again, the Expo has broken previous records for number of exhibitors and number of booths, with more than 700 exhibitors in more than 1,700 booths. While you are visiting the exhibit hall, dont forget to check out the more than 800 posters that will be presented in groups during exhibit hours. You will want to plan your time carefully to make sure that you see the exhibitors that offer the products and services you are looking for. The product locator terminals in the registration area can help you plan your exposition time. We also encourage you to use your expo visit time today to walk around and make appointments for later in the weekthe exhibitors will have more time for one-on-one discussions on Wednesday and Thursday. Also, note that exhibit hours for Thursday have been changed. Exhibits will open at 8:30 a.m. and close at 2:00 p.m. We wish you a very successful and enjoyable visit to the 2006 Annual Meeting.
HOURS
Registration
McCormick Place Convention Center
Saturday, July 22 Sunday, July 23 Monday, July 24 Tuesday, July 25 Wednesday, July 26 Thursday, July 27 12 noon 5:00 p.m. 8:00 a.m. 6:30 p.m. 7:00 a.m. 5:00 p.m. 7:00 a.m. 5:00 p.m. 7:00 a.m. 5:00 p.m. 8:00 a.m. 4:00 p.m.
The AACC Booth (#2051 on the exhibit floor) will be open during exposition hours.
Clinical Lab Expo
Thanks to the Annual Meeting Organizing Committee

expresses its gratitude to the Annual Meeting Organizing Committee (AMOC) for its hard work in putting together another exceptional meeting. The AMOC has spent the past 18 months planning and organizing an exciting program featuring a number of new session formatsall designed to provide attendees the type of learning environment that provides the best educational experience. In addition to five outstanding Plenaries, this years program offers half-day and full-day Symposia, truly Interactive Workshops, Short Courses, and early morning and noontime Brown Bag sessions for small group discussions. New for 2006 are sessions called Meet the Expertsseven sessions that feature interactive discussions with the plenary speakers and other invited experts in the field, and two Chairs Invited Sessions organized by AMOC Chair Dr. Daniel Farkas lab workforce issues and lab medicine in the consumer environment. And dont forget, please turn in the ACCENT evaluation forms at each session you attend.
Tuesday, July 25 Wednesday, July 26 Thursday, July 27
9:30 a.m. 5:00 p.m. 9:30 a.m. 5:00 p.m. 8:30 a.m. 2:00 p.m.
AACC
Across from the Registration Area.

Sunday, July 23 Monday, July 24 Tuesday, July 25 Wednesday, July 26 Thursday, July 27 9:00 a.m. 5:00 p.m. 9:00 a.m. 5:00 p.m. 9:00 a.m. 5:30 p.m. 9:00 a.m. 5:30 p.m. 8:30 a.m. 2:00 p.m.
AACC Bookstore
Plenary Sessions
Sunday, July 23 Monday, July 24 Tuesday, July 25 Wednesday, July 26 Thursday, July 27 5:00 p.m. 6:30 p.m. 8:45 a.m. 10:15 a.m. 8:45 a.m. 10:15 a.m. 8:45 a.m. 10:15 a.m. 12:30 p.m. 2:00 p.m.
2006 Annual Meeting Organizing Committee

ChairDaniel H. Farkas, PhD, HCLD, Chondrogene, Inc., Toronto, Canada Vice-ChairsThomas Annesley, PhD, University of Michigan, Ann Arbor, Mich. Stephen Kahn, PhD, Loyola University Medical Center, Maywood, Ill. Symposia CoordinatorsAndrea Ferreira-Gonzalez, PhD, Medical College of Virginia, Richmond, Va.; Rogerio Rabelo, MD, PhD, Fleury Diagnostics, So Paulo, Brazil Workshop/Short Course CoordinatorsMarcy Anderson, PhD, Medical Automation Systems, Charlottesville, Va.; Kenneth Bahk, PhD, Nanosphere, Inc., Northbrook, Ill. Brown Bag CoordinatorJoan Gordon, Maine Molecular QC, Inc., Scarborough, Maine Abstracts CoordinatorKristen Skogerboe, PhD, Seattle University, Seattle, Wash. Volunteer CoordinatorDeanna Klosinski, PhD, Petoskey, Mich. StaffGail Mutnik, MPA, AACC, Washington, D.C.
Interactive Workshops and Short Courses

Sunday, July 23 Monday, July 24 Tuesday, July 25 Wednesday, July 26 10:30 a.m. 12 noon 1:30 p.m. 4:00 p.m. 10:30 a.m. 12 noon 2:30 p.m. 5:00 p.m. 10:30 a.m. 12 noon 2:30 p.m. 5:00 p.m. 10:30 a.m. 12 noon 2:30 p.m. 5:00 p.m.
Future AACC Annual Meetings
Brown Bag Sessions

Monday, July 24 7:30 a.m. 8:30 a.m. 12:30 p.m. 1:30 p.m. 7:30 a.m. 8:30 a.m. 12:30 p.m. 1:30 p.m. 7:30 a.m. 8:30 a.m. 12:30 p.m. 1:30 p.m.
2007
July 1519 San Diego, Calif.
2008
July 2731 Washington, D.C.
2009
July 1923 Chicago, Ill.
Tuesday, July 25 Wednesday, July 26
For information on other sessions, please see the program guide.

Employer-Managed Healthcare: Corporations Get Back into the Healthcare Business

Tuesday, July 25, 8:4510:15 a.m. Current Position: President, QuadMed, LLC and QuadMed Corporate Health Services (West Allis, Wis.) Education: Marquette University Medical School (now Medical College of Wisconsin, Milwaukee), MD Previous Positions: Faculty of University of Washington School of Medicine; Internal medicine practice in Bellevue, Wash.
substantial expansion of Quad/Graphics on-site medical facilities, which now number four. In his role as President of QuadMed, he oversees a staff of 240including 40 physicians and other medical providers. In addition, he practices internal medicine and specializes in nephrology, the study of the kidney and its functions. As President of QuadMed Corporate Health Services, Quadracci oversees a variety of corporate health care services, including health care clinic management and occupational medicine services such as executive physicals and pre-employment screenings. In addition, he currently oversees the management of health care clinics for Miller Brewing Co. and Briggs & Stratton. A graduate of Marquette University and the Marquette University Medical School (now the Medical College of Wisconsin) in Milwaukee, Quadracci spent more than 20 years on the faculty of the University of Washington School of Medicine in Seattle, where he ultimately became an Associate Professor of Medicine and Pathology before joining QuadMed. In addition, he practiced internal medicine for 18 years in Bellevue, Wash. He also established the Lake Washington Kidney Center in Bellevue in 1981 and served as its medical director for 15 years. For his plenary talk, Employer-Managed Healthcare: Corporations Get Back into the Healthcare Business, Quadracci will speak about the evolution of the QuadMed program, including why the company decided to bring laboratory services in-house and the implications of that move, as well as what he believes are the important factors that improve quality and control costs in CLN health care.
Leonard Quadracci, MD
Richard Pizzi
Managing EditorBill Malone BUSINESS STAFF V.P. Marketing ProgramsJerry Goldsmith Circulation ManagerMickie Napoleoni BOARD OF EDITORS ChairSteve Manzella, PhD, York Hospital, Tuesdays Plenary Speaker, Leonard Quadracci, MD
York, Pa.
Managing Health Care in the Corporate World For more than 35 years, Leonard Quadracci, MD, has been practicing medicine and directing health care services as the President of QuadMed, LLC, and QuadMed Corporate Health Services. Since joining the company in 1995, he has directed health care management for Quad/Graphics, a commercial printer based in Sussex, Wisconsin. While focusing on the quality, accessibility, and affordability of medical care for Quad/Graphics 12,000 employees, Quadracci has also emphasized wellness and preventive care, and has enabled the company to keep rising health care costs in check. For example, Quad/Graphics pays 20 percent less than the average Wisconsin employer for employee medical costs. During his tenure with QuadMed and Quad/Graphics, Quadracci has overseen the
Edwina Szelag Selected as 2006 Point-of-Care Coordinator of the Year

AACCs Critical and Point-of-Care Testing Division honors the contributions of point-of-care coordinators to excellence in health care through its Point-of-Care Coordinator of the Year program. This year the honor goes to Edwina Szelag from Holmes Regional Medical CenterHealth First, Inc. in Melbourne, Fla. As POCT Coordinator for Health First, a three-hospital integrated health care delivery system in Brevard County Florida, Ms. Szelag is responsible for leading and implementing initiatives that focus on performance improvement, quality assurance, communication, and education and accreditation compliance relating to POCT. The Health First system includes Holmes Regional Medical Center, Palm Bay Community Hospital, and Cape Canaveral Hospital. Services and specialties include womens and childrens, outpatient centers for surgery, endoscopies, wound care, pain management, diabetes, home care, hospice, cancer, heart, stroke, and rehabilitative services. In addition, the system is also home to the countys only trauma center and Vital Watch, or eICU. Under her guidance, the organization continues to be accredited for all bedside testing under CAP and JCAHO. Not only has the organization grown, but the POCT program has also expanded. In 1996, Health First POCT consisted of five different POCT tests; today it oversees 11 different test methods, over 1,700 operators, and volumes have grown exponentially. Ms. Szelag earned her Bachelor of Science degree in Medical Technology from Quinnipiac College in Connecticut. As a student intern in Yales School of Medicine Medical Technology Program, she worked in the clinical chemistry department at Yale New Haven Hospital. Upon relocation to Florida, she worked as a technologist in the blood bank at Plantation General Hospital in Plantation Florida and then became a senior technologist in hematology and coagulation at Broward General Medical Center in Fort Lauderdale, Fla. Prior to moving to Melbourne, she earned her Masters in Health Management from St. Thomas University in Miami. She joined the staff of Holmes Regional Medical Center in 1990, where she has held positions as a senior technologist in hematology and as senior technologist over the laboratorys STAT Lab. In 1995, Ms. Szelag became the assistant in laboratory administration for quality assurance and began to work with a bedside testing program still in its infancy. Her impact on improving the quality and safety of the POCT program has been far-reaching across the system and is best illustrated by her active participation and outstanding contributions in several continuum of care and performance improvement teams at all three hospitals, as well as the corporate level. Her program involves representatives from all areas involved in testing, and each is trained to the knowledge and standards expected for POCT. Regular meetings as well as newsletters and electronic-based testing modules help to keep communication and competency on the forefront. Ms. Szelag also remains an active instructor at new associate orientation, skill fairs, and a monthly adult diabetes support group. She continues to dedicate herself to defining best practices for POCT, and as such, has become a strong leader in the POCT community. In addition to forming and supervising the POCT program at Health First, Ms. Szelag has also been instrumental in creating the Florida East Coast Point-of-Care Testing Coordinators Conference which has been held each fall in Cocoa Beach, Fla. since 2000. In 2003, along with the support of other POCCs in the Central Florida area, this conference merged into the Central Florida POC Network . She is Co-Chair of this group, which was also responsible for hosting the recent AfterGlow event enjoyed by hundreds of POCCs in attendance at the AACC Annual Meeting held last year in Orlando. She continues to be a speaker at local, state, and national educational seminars on POCT topics, including implementation of critical care programs for POCT and issues in compliance. This auspicious award, sponsored by the AACC CPOCT Division and funded by Lifescan, Inc., includes a cash award, funding to attend the AACC Annual Meeting, and an elegant trophy. The award will be presented at the CPOCT Division Mixer on Tuesday, July 25, 68 p.m., at the Hyatt Regency Chicago Hotel.
The National Academy of Clinical Biochemistry

The Academy of AACC
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INDEX TO ADVERTISERS
2006 NACB Distinguished Abstract Awards

The NACB is proud to announce the following recipients of its 2006 Distinguished Abstract Awards. This Academy program is designed to recognize scientific excellence among abstracts accepted for presentation at the AACC 2006 Annual Meeting. The following 13 abstracts were chosen from 629 abstracts accepted for presentation at the meeting. A rigorous selection process is used that incorporates a primary review by AACC members followed by a second review performed by a group of NACB Fellows. Only those abstracts that meet strict criteria during both reviews are designated as Distinguished Abstracts. Tuesday, July 25, 10:00 a.m. A-27 Jacoline Brinkman Cystatin C is a predictor of cardiovascular morbidity and mortality independent of renal function and other cardiovascular risk factors. Tuesday, July 25, 10:00 a.m. A-87 Jasper Remijn Novel molecular defect in the platelet ADP receptor P2Y12 in a patient with a history of unexplained severe congenital bleeding. Tuesday, July 25, 2:00 p.m. B-18 Ronald Pang Serum proteomic profiling identified betathromboglobulin and platelet factor 4 as prognostic indicators in severe acute respiratory syndrome. Tuesday, July 25, 2:00 p.m. B-64 Yusheng Zhu, PhD Genotyping of VKROC1 polymorphisms (1639G>A) for patients on Warfarin therapy using allele-specific primer extension assay. Wednesday, July 26, 10:00 a.m. C-111 Irina Kirpich Free fatty acid composition of blood serum in patients with acute alcoholic psychosis. Wednesday, July 26, 2:00 p.m. D-3 Fred Apple, PhD Multibiomarker profiling for detection of adverse events in acute coronary syndrome patients. Wednesday, July 26, 2:00 p.m. D-21 David Gaze Oxidised low-density lipoprotein (ox-LDL)
is a poor short-term event marker in acute coronary syndrome patients who present to the emergency department.
Wednesday, July 26, 2:00 p.m. D-44 Qing Meng, PhD, MD The protective role of hydrogen sulfide in the pathogenesis of atherosclerosis. Wednesday, July 26, 2:00 p.m. D-52 David Pritchard, PhD Activated Factor XII Type A strongly predicts all cause mortality after hospitalization with chest pain. Thursday, July 27, 9:00 a.m. E-4 Romolo Dorizzi, MD Diagnostic odds ratios of different S-100 B protein concentrations in the follow-up of malignant melanoma. Thursday, July 27, 9:00 a.m. E-19 Shu-Ling Liang, PhD A pharmacoproteomic approach to evaluate the effects of an epidermal growth factor receptor inhibitor on tumor tissues. Thursday, July 27, 9:00 a.m. E-24 Rama Mittal, PhD Inter-relationship between prostate specific antigen, kallikrein-2 and androgen receptor gene polymorphisms with risk of prostate cancer in India. Thursday, July 27, 9:00 a.m. E-77 Brad Karon, PhD, MD Monitoring glucose concentration in patients on intensive intravenous insulin therapy.
Alifax S.P.A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 Antek HealthWare . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Artel Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Bayer HealthCare, Diagnostics Division . . . . . . . . . . . . . . . . . . . . . . . . 52 BD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Bio-Rad Laboratories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25, 33 Biosite Incorporated . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23, 35 College of American Pathologists . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Diamedix Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 DRG International, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Eppendorf AG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45, 47, 49 Eppendorf, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 (insert), 11, 13 INOVA Diagnostics, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Invetech Pty Ltd . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 LifeScan, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 & 5 Medical Laboratory Evaluation (MLE) . . . . . . . . . . . . . . . . . . . . . . . . . 22 Midland Bioproducts Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Olympus America, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Ortho-Clinical Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17, 19, 21 Precision Systems, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Protedyne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 Quest Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Randox Laboratories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Roche Diagnostics Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Scantibodies Laboratory, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Sysmex America, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Utak Laboratories, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Waters Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
OEM
Fluid Metering, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 KMC Systems, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 Michigan Diagnostics, LLC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Millipore Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 Oyster Bay Pump Works, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 ZeptoMetrix Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42
The Society for Young Clinical Laboratorians

BY LINNEA M. BAUDHUIN, PHD
Chair, SYCL AACCs Society for Young Clinical Laboratorians (SYCL) marks its two-year anniversary this week. Created in 2004 to meet the needs of AACCs young and student members, our mission is to develop programs that support and encourage career development in the clinical laboratory sciences. Membership in SYCL is automatic for individuals who are under 40 years of age or who are registered as a student member of AACC. You can easily spot SYCL members by the logo stickers on their badges. Here in Chicago, SYCL has organized two special events. Following the Monday afternoon student poster contest, we are hosting a networking reception for SYCL members and AACC leaders. On Thursday morning, from 9:30 a.m. to 12:00 p.m., all are invited to a free SYCL-organized symposium entitled Making Sense of the Alphabet Soup of Laboratory Regulations, which will provide attendees with a better understanding of the numerous regulatory and accreditation requirements for clinical laboratories. In addition our existing programs, SYCL is introducing some new activities aimed at supporting young clinical laboratorians. For example, we were pleased to support this years inaugural winners of the SYCL Domestic Travel Grant: Christopher McCudden, from Duke University Medical Center (Raleigh, N.C.), and Alagarraju Muthukumar, from the University of Texas Southwestern Medical Center (Dallas, Texas). This grant was funded by the Van Slyke Foundation and supported in part by the Foundation for BD Diagnostics. To aid junior clinical laboratory professionals in employment negotiations, we have also updated our Web site with tips and questions to ask potential employers, and we are developing an employment and salary survey. And soon to be posted on our Web site, updated tips and information for laboratorians who are preparing for the American Board of Clinical Chemistry certification exam. The SYCL Seminar Series (SSS), designed to promote clinical laboratory science as a career to young scientists, was a huge success last year thanks to our fantastic speakers: Niki Baumann, William Clarke, David Colantonio, Corrine Fantz, and Carmen Wiley. Now in its second year, the SSS is hoping to continue its success with promotion by these outstanding SYCL members: Joshua Bornhorst, Bonnie Bukavecas, Shannon Haymond, Alex Rai, Kristin Reynolds, Amy Saenger, and Jennifer Snyder. 2007 looks to be an equally exciting and active year for SYCL. We plan to continue the Mentor of the Month and SYCL Seminar Series, update and make additions to the SYCL Web site, and promote events at the AACC Annual Meeting. For more information, please visit our Web site at www.aacc.org/sycl.
Happy Second Anniversary
51
INDUSTRY WORKSHOPS
More Great Learning Opportunities

TUESDAY, JULY 25 7:00am8:30am ABBOTT LABORATORIES Fairmont Hotel, Gold Room Laboratory Automation: Process Improvement Through a Family of Integrated Analyzers
Speakers: Pennell Painter, PhD, FACB, Dynacare Tennessee Laboratory, University of Tennessee Medical Center Michael J. Nicar, PhD, Baylor University Medical Center Gary S. Assarian, DO, FACP, Hospital Consolidated Laboratory, Southfield, Mich.
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, Crystal Room
A Molecular Laboratory Startup

Speakers: Bryan Moore, PhD, Roche Diagnostics Scott Sargent, Roche Diagnostics
Emergence of Wet Diagnostic Urinalysis and the Clinical Value of Body Fluid Cell Counts
IRIS DIAGNOSTICS, INC. Fairmont Hotel, Imperial Ballroom
Hepatitus B Virus: Everything I Did Not Learn in School
ORTHO-CLINICAL DIAGNOSTICS Fairmont Hotel, Crystal Room
ROCHE DIAGNOSTICS CORP. Hyatt Regency Chicago, Grand Ballroom B
LeanIts a Lifestyle not a Diet

Speakers: Caroline Ambrose, MT(ASCP), CQM(ASQ), Healthcare Solutions Anne Daley, MS, MT(ASCP), DLM, Healthcare Solutions
Speaker: G. Barry Schumann, MD, Schumann Diagnostics, University of Pennsylvania Nancy Bruneel, MS, CLS (NCA), University of Minnesota
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, Crystal Room
Speakers: Robert Dufour, MD, George Washington University J. Schappert, MD, Beth Israel Medical Ctr., N.Y. E. EchevarriaPhD, National Center of Microbiology, Spain P. Kilmartin, PhD, Ortho-Clinical Diagnostics
AmpliChip CYP450 Testing: Going Clinical

Speakers: Zixuan Wang, PhD, MDx Brigitte Fernandez-McAlear, Roche Diagnostics
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, Gold Room
ROCHE DIAGNOSTICS CORP. Hyatt Regency Chicago, Grand Ballroom A
FDA Guidelines for Validation of Rules and a Rules-Sharing Workshop

Speakers: James Callahan, FDA Jon Wearly, FDA Bill Coughlin, Data Innovation
ABBOTT LABORATORIES Fairmont Hotel, International Ballroom
Natriuretic Peptides Clearing the Confusion

Speakers: Robert H. Christenson, PhD, University of Maryland Medical center Christopher deFillipi, MD, University of Maryland School of Medicine Paul Collinson, MD, PhD, St. Georges University Teaching Hospital, U.K.
New Markers in Laboratory Medicine

Speakers: Ravi Thadhani, MD, MPH, Harvard Medical School Prasad Devarajan, MD, Cincinnati Childrens Hospital Medical Center, University of Cincinnati Oscar Segurado, MD, PhD, Abbott Immunology
Understanding Evidence Based Outcomes of Automation with a Single Solution from Roche Diagnostics
Speakers: TBD
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, Moulin Rouge
SEBIA ELECTROPHORESIS Fairmont Hotel, Regent Room
SERADYN, INC. Fairmont Hotel, Moulin Rouge
Pharmacogenetic Testing in the Clinical Setting

Speakers: TBD
TM BIOSCIENCE CORPORATION Fairmont Hotel, International Ballroom
Capillary Electrophoresis Technology: Recent Menu Expansions Allowing Completely Automated Immunofixation and Hematology Variant Testing
Speaker: Genevieve Hennache, PhD, Parc Technologique Leonard de Vinci, France
BECKMAN COULTER, INC. Hyatt Hotel, Columbus Hall IJ
Automation: Selling It to the Board Administrative Director View (Part 1)

Speakers: Judy Darr, Pinnacle Health Hospitals Doug Schreffer, Pinnacle Health Hospitals
QMS Lamotrigene Immunoassay: The First Available Immunoassay for the Quantitative Determination of Lamotrigene Levels in Human Serum or Plasma
Speakers: Mark Roberts, PhD, Seradyn, Inc. Lili Arabshahi, PhD, Seradyn, Inc. Melissa Wall, BS, Seradyn, Inc.
WEDNESDAY, JULY 26 7:00am8:30am ABBOTT LABORATORIES Fairmont Hotel, International Ballroom The Impact of Cardiac Biomarkers on Clinical Practice
Solving Problems in the Laboratory Using Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
Speakers: David s. Milligan, PhD, Duke University Medical Center Other speakers TBD
WATERS CORPORATION Fairmont Hotel, Imperial Ballroom
BECKMAN COULTER, INC. Hyatt Hotel, Columbus Hall KL
Impact of Preanalytical Error on Immunoassay Results

Speakers: Sheila Hanna, PhD, Beckman Coulter, Inc. Nancy Dubrowny, MS, MT(ASCP)Sc, Beckman Coulter, Inc.
TUESDAY, JULY 25 6:00pm7:30pm ABBOTT LABORATORIES Fairmont Hotel, Gold Room Immunoflowcytometry in Routine Hematology
Speakers: Richard Kimball, PhD, Abbott Hematology Bruce Davis, MD, Trillium Diagnostics, LLC
Speakers: Fred S. Apple, PhD, DABCC, Hennepin County Medical Center Per Venge, MD, PhD, University Hospital, Uppsala, Sweden Stanley L. Hazen, MD, PhD, Cleveland Clinic Alan H.B. Wu, PhD, University of California, San Francisco
WEDNESDAY, JULY 26 6:00pm7:30pm ABBOTT LABORATORIES Fairmont Hotel, International Ballroom Current Trends in Hepatitis and Retrovirus Diagnostic Testing
BIO-RAD LABORATORIES Fairmont Hotel, Imperial Room
APPLIED BIOSYSTEMS Hyatt Regency Chicago, Regency Ballroom A
The Clinical Utility of A1C Testing for the Diabetic Patient & Method Selection
Speakers: David Sacks, MD, Brigham and Womens Hospital Alvin Michael Spiekerman, PhD, Texas A&M Medical School Trefor Higgins, MSc, Dynacare Kaspar Medical Laboratories, Alberta
The Use of Tandem Mass Spectrometry in Clinical Research: Technology and Applications
Speaker: Michael Baynham, PhD, Applied Biosystems
Speakers: Dr. Philip Cunningham, NSW State Reference Laboratory for HIV, St. Vincents Hospital, Darlinghurst, Australia Bernard Weber, MD, Laboratories Reunis Junglinster, Luxembourg
Introduction to LC/MS/MS for Clinical Research

Speaker: Michael Baynham, PhD, Applied Biosystems
BECKMAN COULTER, INC. Hyatt Hotel, Crystal Ballroom A
Immunoflowcytometry in Routine Hematology (presented a second time) Results of Recent Clinical Research HPLC/Tandem Mass Spectroscopy
Speakers: TBD
ABBOTT LABORATORIES Fairmont Hotel, Gold Room
CENTERCHEM, INC./PENTAPHARM, LTD. Hyatt Regency Chicago, Grand Ballroom A
Automation: Making It Happen Lab Operations Director View (Part 2)

BECKMAN COULTER, INC. Hyatt Hotel, Crystal Ballroom B
DIAGNOSTIC PRODUCTS CORPORATION Hyatt Regency Chicago, Regency Ballroom A
Anticoagulant Monitoring with Pefakit PiCT

Speaker: Dorothy Adcock, MD, Esoterix Coagulation-LabCorp
Speakers: Judy Darr, Pinnacle Health Hospitals Doug Schreffer, Pinnacle Health Hospitals
Interpreting NT-proBNP Results in Acute and Primary Care Settings

Speakers: Paul O. Collinson, MD, FRCPath, FACB St. Georges Hospital and Medical school, U.K.
COHESIVE TECHNOLOGIES INC. Hyatt Regency Chicago, Grand Ballroom B
HYTEST LTD./INNOTRAC DIAGNOSTICS Fairmont Hotel, State Room
Early Cardiac Triage in the Troponin Era

Speakers: Fred S. Apple, PhD, DABCC, Hennepin County Medical Center Alexei Katrukha, PhD, HyTest Ltd. Kim Pettersson, PhD, Univ. of Turku, Finland Susann Eriksson, PhD, Univ. of Turku, Finland Qiu-Ping Qin, PhD, MD, Univ. of Turku, Finland Saara Wittfooth, MSc, Univ. of Turku, Finland
Overcoming Sample Preparation Bottlenecks and the High Cost Associated with Tandem Mass Spectroscopy for Validated Clinical Diagnostic Assays
Speakers: Jean M. Lacey, Mayo Clinic Pierre Marquet, PhD, University Hospital of Limoges, France Joseph DiBussolo, PhD, University of West Chester
Speakers: Bernard C. Cook, PhD, DABCC, FACB, Beckman Coulter,Inc. Allan S. Jaffe, MD, Mayo Clinic
False Positive Cardiac Troponins: True or False
ORTHO-CLINICAL DIAGNOSTICS Fairmont Hotel, Crystal room
Small Dense LDL: Method Validation and Relationship with Severity in Stenosis
DENKA SEIKEN CO., LTD. Fairmont Hotel, State Room
Speakers: Claudia French, BSMT, MBA, Ortho-Clinical Diagnostics Dee Holm, BSMT, MBA, Sacred Heart Hospital, Wash.
Lean Driven Laboratory Design
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, Moulin Rouge
Culture Matters! Why?
DAVID G. RHOADS ASSOCIATES, INC. Fairmont Hotel, Regent Room
Speakers: Elizabeth Teng Leary, PhD, Pacific Biometrics, Inc. Shinji Koba, MD, Showa University School of Medicine, Japan
Speaker: June Smart, PhD, MBA, CLD, CLS, Healthcare Solutions
ROCHE DIAGNOSTICS CORP. Hyatt Regency Chicago, Columbus Hall AB
ORTHO-CLINICAL DIAGNOSTICS Hyatt Regency Chicago, Regency Ballroom B
Establishing Performance Standards for Clinical Laboratory Instruments

Speaker: David G. Rhoads, PhD, DABCC, David G. Rhoads Associates, Inc.
Do You Know What You are Paying For? How Four Laboratories Used 21st Century Metrics to Find Out
Speakers: Jacqueline Vealey, MT (ASCP) SH, Ortho-Clinical Diagnostics Maureen Harte, MT(ASCP), Ortho-Clinical Diagnostics Other speakers TBD
DIAGNOSTIC PRODUCTS CORPORATION Hyatt Regency Chicago, Regency Ballroom B
An Overview of Food Allergies and Co-morbid Conditions: Atopic Dermatitus (AD) to Eosinophilic Gastrointestinal Disorders (EGID) & More
Speaker: Miles Mirhosseini, MD, Diagnostic Products Corporation
DIAGNOSTIC PRODUCTS CORPORATION Hyatt Regency Chicago, Regency Ballroom B
Leveraging Analytics to Support Population Outcome Studies

Speaker: Jay B. Jones, PhD, DABCC, Geisinger Health System
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, State Room
Molecular TechnologiesBridging the Research & Diagnostic Laboratories

Speaker: Lonnie Schoft, Roche Diagnostics
Dealing with Common QC Problems

Speakers: Jim Aguanno, PhD, Diagnostic Products Corporation Nils Person, PhD, Diagnostic Products Corporation Mark Smith, Diagnostic Products Corporation
FOCUS DIAGNOSTICS Fairmont Hotel, Moulin Rouge
MILLENIA DIAGNOSTICS, INC. Fairmont Hotel, Regent Room
Interpretation of Genetic Tests Using Cystic Fibrosis (CF) as a Paradigm

ORTHO-CLINICAL DIAGNOSTICS Hyatt Regency Chicago, Regency Ballroom C
ROCHE DIAGNOSTICS CORP. Fairmont Hotel, Regent Room
Speaker: Jean Amos Wilson, PhD, Focus Diag.
Real-Time PCRHands-on Introductory Workshop

Speaker: John Osieck, PhD, Roche Diagnostics
Emerging Technologies in Rapid Diagnostics

Speakers: Danny Levenson, BS, Millenia Diagnostics, Inc. Ryan Knoth, BS, Millenia Diagnostics, Inc. Bill Doering, PhD, Oxonica, Inc.
ILLUMINA Fairmont Hotel, State Room
Comprehensive Coverage: Illuminas Digital Microbead Array Technology

Speaker: David Barker, PhD, Illumina
Contemporary Issues for the Clinical Laboratory in the Diagnosis and Management of Diabetes Mellitis
Meeting Clinicians Needs in Hematology Testing
SYSMEX AMERICA, INC. Fairmont Hotel, Imperial Ballroom
Speaker: William Roberts, MD, PhD, ARUP, University of Utah Medical Center
Speakers: Thomas kickler, MD, Johns Hopkins Medical Center Anne Tate, Sysmex America, Inc. As of May 1, 2006

Harvey V. Fineberg, MD, PhD

Crossing the Quality Chasm: The Role of Laboratory Medicine
Sunday, July 23, 5:006:30 p.m. Current Position: President, Institute of Medicine. Education: Harvard UniversityMD, 1972; PhD, 1980; BS, 1967. Previous Positions: Provost, Harvard University; Dean, Harvard School of Public Health.
Richard Pizzi
Managing EditorBill Malone BUSINESS STAFF V.P. Marketing ProgramsJerry Goldsmith Circulation ManagerMickie Napoleoni BOARD OF EDITORS ChairSteve Manzella, PhD, York Hospital,
York, Pa.
Sundays Plenary Speaker, Harvey V. Fineberg, MD, PhD
Dedicated to Public Health Harvey Fineberg has devoted most of his career to the improvement of public health policy and medical decision making. To meet the publics health needs and to fulfill the promise of science for health have never been more compelling social goals, Fineberg said when accepting his appointment to become the seventh president of the Institute of Medicine (IOM), the position he now holds. Chartered in 1970 by the National Academy of Sciences (NAS), the IOM enlists distinguished members of the health professions to advise the government on issues such as vaccine safety, health care delivery and quality, nutrition standards, cancer prevention and management, and military and veterans health. A member of IOM since 1982, Fineberg chaired the NAS committee that wrote Understanding Risk: Informing Decisions in a Democratic Society and served as either chair or co-chair of the committees that authored the reports No Time to Lose: Getting
More from HIV Prevention, Americas Vital Interest in Global Health, Adverse Effects of Pertussis and Rubella Vaccines, and Societys Choices: Social and Ethical Decision-Making in Biomedicine. His broad research interests encompass AIDS and other infectious diseases, the evaluation of diagnostic tests and vaccines, the fields of risk assessment and decision making, the ethical and social implications of new medical technologies, and medical education. Prior to assuming his current role as IOM President, Fineberg served as Provost of Harvard University from 19972001, following thirteen years as Dean of the Harvard School of Public Health. He was a member of the Schools faculty for eleven years before becoming Dean, during which time he also worked as a practicing physician at two Boston-area health centers. Fineberg helped found and served as president of the Society for Medical Decision Making and has also served as a consultant to the World Health Organization.
Fineberg co-authored The Epidemic that Never Was, an analysis of the controversial federal immunization program against swine flu in 1976, and has co-authored and edited several other books on subjects such as HIV prevention and understanding risk. In 1998, he received the Joseph W. Mountain Prize from the Centers for Disease Control and Prevention and the Wade Hampton Frost Prize from the Epidemiology Section of the American Public Health Association. In his plenary lecture, Fineberg discussed initiatives and activities in the U.S. health care system that emphasize the role of laboratory medicine in bridging the gap that exists between the desired and actual levels of quality in U.S. health care, particularly regarding patient safety and medical errors. He identified certain key obstacles that must be overcome to improve the quality of health care delivery, and described the opportunities available for those in laboratory medicine to contribute to further narCLN rowing the quality chasm.
Caroline Kovac, PhD
Computing in the Age of the Genome

Monday, July 24, 8:4510:15 a.m. Current Position: General Manager, IBM Pharmaceutical and Life Sciences, Somers, N.Y. Education: University of Southern California, PhD, Chemistry; Oberlin College, BA Previous Positions: Vice President, Technical Strategy and Division Operations; Vice President, Services and Solutions, IBM Professional Activities: Board of Directors, Africa Harvest Biotech Foundation International; Board of Directors, Research!America
business unit with only two employees in 2000, Kovac grew the life sciences business unit into a multi-billion dollar business. The Life Sciences venture is one of IBMs most successful ventures to date with more than 1,500 employees worldwide. In addition to this position, Kovac has held a number of executive management positions over her more than 20 years at IBM, including vice president of Technical Strategy and Division Operations, and vice president of Services and Solutions. In the latter role, she was instrumental in launching the Computational Biology Center at IBM Research. Kovac holds a PhD in Chemistry from the University of Southern California in Los Angeles and a BA from Oberlin College in Ohio. Her professional activities include sitting on the Board of Directors of Africa Harvest Biotech Foundation International, an organization focused on using technology as a tool to fight hunger, malnutrition and poverty in Africa, and Research!America, an alliance of health care professionals working to increase the research investment budgets of federal health care agencies. She is a frequent speaker and panelist at numerous life sciences and health care forums worldwide, and served as an expert panelist for the 2004 World Economic Forum and the 2003 Time Magazine Future of Life Summit. In 2002, Kovac was inducted into the Women in Technology International Hall of Fame, and she is a member-emeritus of the IBM Academy of Technology. In 2004, Kovac was named one of the 50 most powerful women in business by Fortune magazine and in 2005 won the Scrip Pharmaceutical CLN Executive of the Year Award.
Mondays Plenary Speaker, Caroline Kovac, PhD
Pioneering Life Sciences Since 2004, Caroline Kovac, PhD has been General Manager and responsible for the strategic direction of IBMs global pharmaceutical and life sciences business. She and her team develop the latest information technology solutions and services, which includes establishing partnerships and overseeing IBM investment within the health care, pharmaceutical, and life sciences markets. In this role, Kovac works closely with a wide variety of leaders in health care and life sciences, including medical centers and academic institutions, as well as leading biotech and pharmaceutical companies, to pioneer information-based medicine. Prior to assuming her present position, Kovac was General Manager of IBM Life Sciences. After its launch as an emerging
AACC
NATIONAL ELECTIONS SLATE OF CANDIDATES
AACC Members to Elect New Leaders by Electronic Ballot in August

Photo by Christies Photography, taken at the 2005 Annual Meeting.
ont miss the opportunity to elect the future leaders of AACC. The voting period begins August 1 and ends August 30, and members will receive voting instructions in late July . Further details of the electronic voting process will be provided in AACC eNews. This election will determine the president-elect for 2007, who will become the AACC president in 2008. In addition, a treasurer, two members of the board of directors, and four members of the nominating committee will be elected.
PRESIDENT-ELECT
LARRY A. BROUSSARD, PHD, DABCC, FACB

AACC Member: 30 Years Position: Professor, LSU Health Sciences Center in New Orleans, La. and Director of the Toxicology Laboratory of the Orleans Parish Coroners Office.
STEVEN H. WONG, PHD

AACC Member: 26 Years Position: Professor of Pathology, Co-Director, Clinical Chemistry/Toxicology, Therapeutic Drug Monitoring (TDM), Pharmacogenomics and Proteomics, Department of Pathology, and Professor of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, Wis.; Co-Director, Clinical Chemistry/Toxicology, Dynacare Laboratory, Froedtert Lutheran Memorial Hospital (MCW Teaching Hospital), and LabCorp, Milwaukee, Wis.; and Toxicology Scientific Director, Milwaukee County Medical Examiners Office.
AACC Presidents Take the Stage

Front row, left to right: Mitchell G. Scott, PhD; Gerald Cooper, MD; Mary Burritt, PhD; Helen Free, DSc; Mary Lou Gantzer, PhD; Larry J. Kricka, PhD, DPhil; John Sherwin, PhD. Second row, left to right: Donald Young, PhD; Jocelyn Hicks, PhD; Susan Evans, PhD; Peter Wilding, PhD; Laurence Demers, PhD. Third row, left to right: Thomas Moyer, PhD; Stephen Kahn, PhD; Nathan Gochman, PhD; Frank Sedor, PhD; Jack Ladenson, PhD; Robert Habig, PhD; Carl Burtis, PhD.
B OA R D O F D I R E C TO R S
N O M I N AT I N G C O M M I T T E E
ANTHONY W. BUTCH, PHD, DABCC, FACB, MT (ASCP)

Professor of Pathology & Laboratory Medicine, and Director, Immunology Research Laboratory, Geffen School of Medicine, University of California, Los Angeles, Calif.; Medical Director of Clinical Chemistry, Toxicology, Endocrinology, and Support Services, University Hospital, Los Angeles, Calif.
KEVIN T. CAVANAGH, PHD, FACB

Division Director, Chemistry & Toxicology, Bureau of Labs, Michigan Department of Community Health, Lansing, Mich.; Laboratory Director, Saginaw County Department of Public Health, Saginaw, Mich.; Associate Adjunct Professor, Department of Medical Technology, Michigan State University.
DAVID GRENACHE, PHD, MT(ASCP)

Assistant Professor of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, N.C.; Associate Director, Core Laboratory, and Director, Special Chemistry and Blood Gas Laboratories, UNC Hospitals, Chapel Hill, N.C.
CATHERINE HAMMETT-STABLER, PHD, DABCC, FACB

Associate Professor, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, N.C.; Director, Clinical Toxicology, Clinical Pharmacology, and Pediatric Metabolism Laboratories, and Associate Director, Core Laboratory, McLendon Laboratories, University of North Carolina, N.C.
PATRICIA M. JONES, PHD, DABCC, FACB

Associate Professor, Pathology and Medical Laboratory Science, UT Southwestern Medical Center; Clinical Director, Chemistry and Client Services, Childrens Medical Center, Dallas, Texas.
EMILY S. WINN-DEEN, PHD

Vice President, Strategic Planning and Business Development, Cepheid, Sunnyvale, Calif.
INGO S. KAMPA, PHD

Manager, Special Procedures Laboratory, Valley Hospital, Ridgewood, N.J.; Consultant, K&K Associates, Inc.
DANIEL H. FARKAS, PHD, HCLD (ABB), CC, CLSP(MBP), FACB

Vice-President for Clinical Diagnostics, ChondroGene, Ltd., Toronto, Canada
LARRY J. KRICKA, DPHIL

Professor of Pathology and Laboratory Medicine, University of Pennsylvania, and Director, General Chemistry Laboratory, Hospital of the University of Pennsylvania, Philadelphia, Pa.
Excerpt from Broussards Platform Statement: My platform statement for the position of Treasurer in 2003 stated that two of the biggest problems we face as an organization and as individuals are: (1) recognition of the value of clinical diagnostics and the laboratory in health care and (2) recruitment of young scientists into our profession. In the past 23 years the Presidents of AACC have initiated what Ill call R & R (recognition and recruitment) programs to address these needs and these efforts must be continued. Recognition of what we do and the value of the services we provide are keys to our survival as a profession. We must continue multiple interactions with clinician organizations to demonstrate our abilities to those ordering laboratory tests and receiving the information that we provide. Through efforts such as development of practice guidelines and organization of meetings involving clinician-laboratorian interaction, the Academy of AACC, NACB, is a valuable asset and the continued movement of increased cooperation between AACC and NACB will provide opportunities for the establishment of stronger relationships with clinician organizations. I will work to strengthen such current programs but also to investigate new approaches to our old problems. In addition to recognition of the value of diagnostic laboratory testing, the recruitment of young scientists into our profession is being addressed by AACC, primarily through the formation of the Society for Young Clinical Laboratorians. The next step in the process is to ensure that there will be opportunities for training the next generation of laboratorians and I will work to continue and enlarge the AACC programs that have been instituted.
Excerpt from Wongs Platform Statement: As an association with diverse membership, AACC offers education, networking, and professional development opportunities. I believe that AACC should map out further approaches to train current members, to recruit new members, and to encourage young members to be active in the Society of Young Clinical Laboratorians. With the completion of the human genome project and the emergence of the human proteome, AACC is in a key position of enhancing the translational research and clinical findings for developing new diagnostics. If elected, I will ensure that functional tests, genomics, proteomics and other omics biomarkers are included in the scientific, technological, and regulatory planning processes. If elected, I would support the establishment of a molecular pathology review course, a focused effort in membership recruitment, and workshops for mentoring and grants proposals. AACC should extend its outreach to pharmaceutical organizations and the Human Genome Organization. In summary, I would work to enable the mutation of the scientific knowledge base and technological expertise of our wellestablished discipline to further embrace the opportunities offered by findings of outcome studies in clinical translational medicine for patient care.
JOSEPH P. MCCONNELL, PHD, DABCC

Laboratory Director, Department of Laboratory Medicine (DLMP), and Co-Director, Immunochemical Core Laboratory, Department of Research, Mayo Clinic, Rochester, Minn.; Assistant Professor, Laboratory Medicine, Mayo Graduate School of Medicine, Rochester, Minn.
TREASURER
ANN GRONOWSKI, PHD, DABCC, FACB

Associate Professor, Washington University School of Medicine, Departments of Pathology & Immunology and Obstetrics & Gynecology, St. Louis, Mo.; Associate Medical Director, Clinical Chemistry, Serology and Immunology, Barnes-Jewish Hospital, St. Louis, Mo.
JAMES H. NICHOLS, PHD, DABCC, FACB

Associate Professor, Pathology, Tufts University School of Medicine, Boston, Mass.; Medical Director, Clinical Chemistry, Baystate Health, Springfield, Mass.

Announcements 06

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The American Association for Clinical Chemistry extends its sincere thanks to the following companies for their

generous support through their contributions.

Bio-Rad Laboratories Abbott Diagnostics

IVD Technology Magazine/ Canon Communications

Cardinal Health, Scientific Products Distribution ACON Laboratories, Inc.

Olympus America, Inc., Diagnostic Systems Group

Dade Behring, Inc.

Selected Area of Research

Technological Innovation Notepads and Pens

Bayer HealthCare, Diagnostics Division

Diagnostic Products Corporation

Contribution for a Publication in the Journal Clinical Chemistry

Contributions to Patient Safety

BD Diagnostics, Preanalytical Systems

Diagnostica Stago, Inc.

Quest Diagnostics Hospital Services

Beckman Coulter, Inc.

Achievements by a Young Investigator

Service to the Profession of Clinical Chemistry

Fujirebio Diagnostics, Inc.

CLINICAL LABORATORY NEWS SPECIAL EDITION

2006 AACC AWARD WINNERS

Clinical Laboratory Science Leaders Receive Awards

Harvey V. Fineberg, MD, PhD

Award for Outstanding Clinical Laboratory Contributions to Patient Safety

Michael L. Astion, MD, PhD

Gary L. Myers, PhD, FACB

Award for Outstanding Contributions To Clinical Chemistry

Herbert A. Fritsche, PhD, FACB

Helen M. Free, DSc

Award for Outstanding Contributions in Education

Catherine A. Hammett-Stabler, PhD, DABCC, FACB

CLINICAL LABORATORY NEWS SPECIAL EDITION

David J. Warren, PhD

International Travel Fellowship

Sarfraz Ahmad, PhD

Award for Outstanding Scientific Achievements by a Young Investigator

Roshini S. Abraham, PhD

The Edwin F. Ullman Award

Larry J. Kricka, PhD

The AACC Past Presidents Award

Mitchell G. Scott, PhD, DABCC, FACB

CLINICAL LABORATORY NEWS SPECIAL EDITION

NACB ALVIN DUBIN AWARD

John E. Sherwin, PhD, DABCC, FACB

Linnea M. Baudhuin, PhD

Stop by the AACC Booth

for the latest info on all our educational programs.

NACB Honors New Academy Fellows

CLINICAL LABORATORY NEWS SPECIAL EDITION

AACC Divisions Recognize Contributions to Laboratory Medicine

Best Abstract of Interest To the Industry Division Recipient: To be announced.

CLINICAL LABORATORY NEWS SPECIAL EDITION

Clinical Laboratory News

PLENARY SPEAKER SPOTLIGHT

The Convergence of Diagnostics and the Transformation of Medicine

Emphasizing Molecular Diagnostics And Disease Prevention

Douglas C. Wallace, PhD

Thursdays Plenary Speaker, Douglas C. Wallace, PhD

A Founder of Mitochondrial Genetics

CLINICAL LABORATORY NEWS SPECIAL EDITION

2006 ANNUAL MEETING

Welcome to the 2006 Clinical Laboratory Exposition

Clinical Lab Expo