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Anachemia Canada. 255 Norman. Lachine (Montreal), Que H8R 1A3 For laboratory use only.
Material uses
CAS #
67-56-1
%
98-100
TLV
Exposure limits: ACGIH TWA 200 ppm (260 mg/m3): STEL 250 ppm (325 mg/m3) (skin)
METHANOL: ORAL (LD50): Acute: 7300 mg/kg (Mouse). 14200 mg/kg (Rabbit). ORAL (LDLo): Acute: 143 mg/kg (Human). DERMAL (LD50): Acute: 15800 mg/kg (Rabbit). VAPOR (LC50): Acute: 64000 ppm (Rat) (4 hour(s)).
METHANOL
page 2/4
Flammable liquid. Methanol burns with a clean clear flame which is almost invisible in daylight. Concentrations of greater than 20% methanol in water can be ignited. Vapor may travel considerable distance to source of ignition and flash back, eliminate all sources of ignition. Vapor forms explosive mixture with air. Container explosion may occur under fire conditions or when heated. Contact with oxidizers may cause fire and/or explosion. Sensitive to static discharge. Not expected to be sensitive to mechanical impact. Emits toxic fumes under fire conditions.
Skin
Inhalation
Material is irritating to mucous membranes and upper respiratory tract. High levels may cause stupor, headache, nausea, vomiting, dizziness, weakness, digestive and visual disturbances, unconsciousness, central nervous system depression, blindness and death. Methanol may also cause liver and kidney damage. Repeated inhalation may cause impairment of lung function and permanent lung damage. NOTE: The odor threshold of methanol is several times higher than the TLV-TWA. Poisonous or fatal if swallowed. Usual fatal dose: 100-125 milliliters (METHANOL). Can affect the optic nerve resulting in blindness. Can cause mental sluggishness, nausea, vomiting, dyspnea, abdominal pain, diarrhea, convulsions, central nervous system depression, coma and death.
Ingestion
METHANOL
page 3/4
Repeated skin contact may cause irritation, dryness, craking, dermatitis, erythema, and scaling. Repeated exposure by inhalation or absorption may cause systemic poisoning, brain disorders, impaired vision, nystagmus and blindness. Inhalation may worsen conditions such as emphysema or bronchitis. May cause heart, kidney, lung, central nervous system, liver, spleen, brain, and eye damage. Methanol is reported to cause birth defects in rats exposed to 20000 ppm. Passes through the placental barrier in animal. In Vitro, limited evidence of mutagenicity (mouse lymphoma forward mutation assay); In Vivo, no information. To the best of our knowledge the chronic toxicity of this substance has not been fully investigated. Medical conditions which may be aggravated: Significant exposure to this chemical may adversely affect people with chronic disease of the central nervous system, skin, gastrointestinal tract and/or eyes, emphysema, bronchitis.
Skin contact
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Call a physician. Wash contaminated clothing before reusing. Discard contaminated leather articles such as shoes and belt.
Inhalation
Remove patient to fresh air. Administer approved oxygen supply if breathing is difficult. Administer artificial respiration or CPR if breathing has ceased. Seek immediate medical attention.
Ingestion
If conscious, wash out mouth with water. Have conscious person drink several glasses of water to dilute. Induce vomiting. Seek immediate medical attention. Never give anything by mouth to an unconscious or convulsing person.
Oxidizing agents, sulfuric acid, zinc diethyl, potassium t-butoxide, phosphorus trioxide, alkylaluminum solutions, acids, reducing agents, acetaldehyde, ethylene oxide, chromic anhydride, bases, metals (example; magnesium, potassium, zinc, etc...), isocyanates, acid anhydrides, acid chlorides, perchloric acid, nitric acid, hydrogen peroxide, sodium hydroxide with chromoform, cyanuric chloride, perchlorates, nitrates. Corrosive to aluminum and lead. Attacks some forms of plastics, rubbers and coatings.
Reaction Products
METHANOL
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Protective Clothing in Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves. Full suit. case of spill and leak
Evacuate and ventilate the area. Eliminate all sources of ignition. DO NOT touch damaged container or spilled material. Stop leak if without risk. Dyke the area with sand or a natural barrier. Use water spray to reduce vapors. Absorb on sand or vermiculite and place in a closed container for disposal. Use non-sparking tools. Transport outdoors. Wash spill site after material pick up is complete. DO NOT empty into drains. Runoff to sewer may create fire or explosion hazard.
Waste disposal
Burn in a chemical incinerator equipped with an after burner and scrubber. According to all applicable regulations. Harmful to aquatic life at high concentrations. Can be dangerous if allowed to enter drinking water intakes. Do not contaminate domestic or irrigation water supplies, lakes, streams, ponds, or rivers.
Store in a cool place away from heated areas, sparks, and flame. Store in a well ventilated area. Store away from incompatible materials. Do not add any other material to the container. Do not wash down the drain. Do not breathe gas/fumes/vapor/spray. In case of insufficient ventilation, wear suitable respiratory equipment. Keep container tightly closed and dry. Do not use pressure to dispense. Keep at temperature not exceeding 25C. Product is highly hygroscopic. Manipulate under an adequate fume hood. Take precautionary measures against electrostatic discharges. Ground the container while dispensing. Ground all equipment containing material. Use only explosion proof equipment. Use non-sparking tools. Watch for accumulation in low confined areas. Empty containers may contain a hazardous residue. Handle and open container with care. Take off immediately all contaminated clothing. This product must be manipulated by qualified personnel. Do not get in eyes, on skin, or on clothing. Wash well after use. In accordance with good storage and handling practices. Do not allow smoking and food consumption while handling. In case of accident or if you feel unwell, seek medical advice immediately (show the label when possible.). Never use welding or cutting torch on or near drum (even empty) because product (even just residue) can ignite explosively.
Engineering controls
Use only in a chemical fume hood to keep airborne levels below recommended exposure limits. Use explosion-proof ventilation equipment. Do not use in unventilated spaces. Vapors are heavier than air and may travel along the ground or pool in low areas. Because vapor is heavy, ventilation must be provided at floor level as well as at higher levels.
3
1 0
NFPA
Validated 10-May-2007