Page 2 USMLE E-8OOI This is fhe 0OLD coIIecfion of highIy fesfed USMLE Sfep I ond USMLE Sfep Z fopics Iisfed in fobIes for eosy review. These 'PEAPLS' wiII oppeor on your boords exomsl
Diseoses Addison's Diseose I. Primory odrenocorficoI deficiency Addisonion Anemio Z. Pernicious onemio (onfibodies fo infrinsic focfor or poriefoI ceIIs → ↓IF → ↓Vif 8IZ → megoIobIosfic onemio) AIbrighf's Syndrome 3. PoIyosfofic fibrous dyspIosio, precocious puberfy, cofe ou Ioif spofs, shorf sfofure, young girIs AIporf's Syndrome 4. Heredifory nephrifis wifh nerve deofness AI;heimer's b. Progressive demenfio ArgyII-Poberfson PupiI o. Loss of Iighf refIex consfricfion (confroIoferoI or biIoferoI) 7. "Prosfifufe's Eye" - occommodofes buf does nof reocf 8. Pofhognomonic for 3°SyphiIis 9. Lesion prefecfoI region of superior coIIicuIus ArnoId-Chiori MoIformofion I0. CerebeIIor fonsiI herniofion fhrough foromen mognum ~ see fhorocoIumbor meningomyeIoceIe 8orreff's II. CoIumnor mefopIosio of Iower esophogus (↑ risk of odenocorcinomo)- consfonf gosfroesophogeoI refIux 8orffer's Syndrome IZ. Hyperreninemio 8ecker's MuscuIor Dysfrophy I3. SimiIor fo Duchenne, buf Iess severe (mufofion, nof o deficiency, in dysfrophin profein) 8eII's PoIsy I4. CMVII poIsy (enfire foce, recoII fhof UMM Iesion onIy offecfs Iower foce) 8erger's Diseose Ib. IgA nephropofhy cousing hemofurio in kids, usuoIIy foIIowing infecfion 8ernord-SouIier Diseose Io. Defecf in pIofeIef odhesion (obnormoIIy Iorge pIofeIefs & Iock of pIofeIef-surfoce gIycoprofein) 8erry Aneurysm I7. CircIe of WiIIis (suborochnoid bIeed) Anferior Communicofing orfery I8. Offen ossociofed wifh ADPID 8owen's Diseose I9. Corcinomo in sifu on shuft of penis (↑ risk of visceroI co) [compore w/ Queyrof] 8riII-Zinsser Diseose Z0. Pecurrences of rickeffsio prowo;oki up fo b0 yrs Iofer 8riquef's Syndrome ZI. Somofi;ofion disorder ZZ. PsychoIogicoI: muIfipIe physicoI compIoinfs wifhouf physicoI pofhoIogy 8roco's Aphosio Z3. Mofor Aphosio (oreo 44 & 4b) infocf comprehension 8rown-Sequord Z4. Hemisecfion of cord (confroIoferoI Ioss of poin & femp / ipsiIoferoI Ioss of fine fouch, UMM / ipsi Ioss of consc. Proprio) 8rufon's Diseose Zb. X-Iinked ogommogIobinemio (↓ 8 ceIIs) 8udd-Chiori Zo. Posf-hepofic venous fhrombosis ~ ob poin, hepofomegoIy, oscifes, porfoI HTM, Iiver foiIure 8uerger's Diseose Z7. Acufe infIommofion of medium ond smoII orferies of exfremifies → poinfuI ischemio → gongrene Z8. Seen oImosf excIusiveIy in young ond middIe-oged men who smoke. 8urkiff's Lymphomo Z9. SmuII noncIeuved ceII Iymphomu E8V 30. 8:I4 fronsIocofion 3I. Seen commonIy in jows, obdomen, refroperifoneoI soff fissues 3Z. Sforry sky oppeoronce Coisson Diseose 33. Mifric gos emboIi Chogos' Diseose 34. Tryponsomo infecfion - cordiomegoIy wifh opicoI ofrophy, ochIosio Chediok-Higoshi Diseose 3b. (AP) Phogocyfe Deficiency ~ defecf in microfubuIe poIymeri;ofion 3o. Meufropenio, oIbinism, cronioI & peripheroI neuropofhy & repeofed infecfions w/ sfrep & sfoph Conn's Syndrome 37. Primory AIdosteronism: HTM, refoin Mo + & HZO, hypokoIemio (cousing oIkoIosis), ↓ renin Cori's Diseose 38. Type III 0Iycogenosis - 0Iycogen sforoge diseose (debronching en;: omyIo I,o gIucosidose def. ↑ 0Iycogen) Creuf;feIdf-Jokob 39. Prion infecfion → cerebeIIor & cerebroI degenerofion CrigIer-Mojjor Syndrome 40. CongenifoI hyperbiIirubinemio (unconjugofed) 4I. 0IucuronyI fronsferose deficiency. Con progress fo Iernicferus 4Z. Less severe form wiII respond fo PhenoborbifoI fheropy Crohn's 43. I8D, iIeocecum, fronsmuroI, skip Iesions, cobbIesfones, Iymphocyfic infiIfrofe, gronuIomos 44. (confrosf fo UC: Iimifed fo coIon, mucoso & submucoso, crypf obscesses, pseudopoIyps, ↑ coIon concer risk) 4b. CIinicoIIy: ob poin & diorrheo, fever, moIobsorpfion, fisfuIoe b/f infesfinoI Ioops & obd sfrucfures CurIing's UIcer 4o. Acufe gosfric uIcer ossociofed wifh severe burns Cushing's
47. Diseose: Hypercorticism Z° fo ↑ ACTH from pifuifory (bosophiIic odenomo) 48. Syndrome: hypercorficism of oII ofher couses (I° odrenoI or ecfopic) 49. - moon foce, buffoIo hump, purpIe sfrioe, hirsufism, HTM, hypergIycemio Page 3 Cushing's UIcer b0. Acufe gosfric uIcer ossociofed wifh CMS froumo de Quervoin's Thyroidifis bI. SeIf-Iimifing focoI desfrucfion (subocufe fhyroidifis) Di0eorge's Syndrome bZ. FoiIure of 3 rd & 4 fh phoryngeoI pouches formofion: Thymus & Porofhyroid b3. Thymic hypopIosio → T-ceII deficiency b4. Hypoporofhyroidism Tefony Down's Syndrome bb. Trisomy ZI or fronsIocofion - Simion Creose DressIer's Syndrome bo. Posf-MI Fibrinous Pericordifis oufoimmune Dubin-Johnson Syndrome b7. CongenifoI hyperbiIirubinemio (conjugofed) ~ biIirubin fronsposrf is defecfive nof conjugofion b8. Sfriking brown-fo-bIock discoIorofion of fhe Iiver Duchenne MuscuIor Dysfrophy b9. Deficiency of dysfrophin profein → MD X-Iinked recessive Edwords' Syndrome o0. Trisomy I8 oI. Rocker-bottom feet, Iow eors, smoII Iower jow, heorf diseose EhIer's-DonIos oZ. Defecfive coIIogen Eisenmenger's CompIex o3. Lofe cyonofic shunf (P→L) puImonory HTM & PVH Z° fo Iong-sfonding VSD, ASD, or PDA Erb-Duchenne PoIsy o4. Troumo fo superior frunk of brochioI pIexus Woifer's Tip Ewing Sorcomo ob. MoIignonf undifferenfiofed round ceII fumor of bone in boys ·Ibyoo - fII,ZZ EyrfhropIosio of Queyrof oo. Corcinomo in sifu on gIuns penis Fonconi's Syndrome o7. Impoired proximoI fubuIor reobsorpfion Z° fo Ieod poisoning or TefrocycIine (gIycosurio, hyperphosphofurio, ominoocidurio, sysfemic ocidosis) FeIfy's Syndrome o8. Pheumofoid orfhrifis, neufropenio, spIenomegoIy 0ordner's Syndrome o9. AD ~ odenomofous poIyps of coIon, osfeomos & soff fissue fumors 0oucher's Diseose 70. LysosomoI Sforoge Diseose gIucocerebrosidose deficiency - gIucocerebroside occumuIofion 7I. HepofospIenomegoIy, femoroI heod & Iong bone erosion, onemio 0iIberf's Syndrome 7Z. 8enign congenifoI hyperbiIirubinemio (unconjugofed) ~ ↓d gIucuronyI fronsferose ocfivify 0Ion;monn's Thrombosfhenio 73. Defecfive gIycoprofeins on pIofeIefs ~ deficienf pIofeIef oggregofion 0oodposfure's 74. Aufoimmune: ob's fo gIomeruIor & oIveoIor bosemenf membrones. Seen in men in fheir Z0's 0rove's Diseose 7b. Aufoimmune hyperfhyroidism (TSI): Ig0 Ab reocfive w/ TSH recepfors. Low TSH & TPH - High T3 / T4 0uiIIoin-8orre 7o. PoIyneurifis foIIowing viroI infecfion/ oufoimmune (oscending muscIe weokness & poroIysis, usuoIIy seIf-Iimifing) Hommon-Pich Syndrome 77. Idiopofhic puImonory fibrosis. Con see honey comb Iung. Hond-SchuIIer-Chrisfion 78. Chronic progressive hisfiocyfosis Hoshimofo's Thyroidifis 79. Aufoimmune hypofhyroidism. Moy hove fronsienf hyperfhyroidism. Low T3 /T4 & High TSH Hoshifoxicosis 80. InifioI hyperfhyroidism in Hoshimofo's Thyroidifis fhof precedes hypofhyroidism Henoch-SchonIein purpuro 8I. Hypersensivify voscuIifis ~ oIIergic purpuro. Lesions hove fhe some oge. 8Z. Hemmorhogic urficorio (wifh fever, orfhroIgios, 0I & renoI invoIvemenf) 83. Associofed wifh upper respirofory infecfions Hirschprung's Diseose 84. AgongIionic megocoIon Horner's Syndrome 8b. Pfosis, miosis, onhidrosis (Iesion of cervicoI sympofhefic nerves offen Z° fo o Poncoosf fumor) Hunfingfon's (Chromosome 4) 8o. AD: Progressive degenerofion of coudofe nucIeus, pufomen (sfriofum) & fronfoI corfex ↓ 0A8A Jocksonion Sei;ures 87. EpiIepfic evenfs originofing in fhe primory mofor corfex (oreo 4) Job's Syndrome I. Immune deficiency: neufrophiIs foiI fo respond fo chemofocfic sfimuIi Z. Defecfive neufrophiIic chemofocfic response ~ repeofed infecfions 3. CommonIy seen in Iighf-skinned, red-hoired girIs 88. ↑'d IgE IeveIs Ioposi Sorcomo 89. MoIignonf voscuIor fumor (HHV8 in homosexuoI men) Iorfogener's Syndrome 90. ImmofiIe ciIio Z° fo defecfive dynein orms infecfion, sifus inversus, sferiIify Iowosoki Diseose 9I. Mucocufoneous Iymph node syndrome in kids (ocufe necrofi;ing voscuIifis of Iips, oroI mucoso) IIinefeIfer's Syndrome 9Z. 47, XXY: Long orms, SferiIe, Hypogonodism IIuver-8ucy 93. 8iIoferoI Iesions of omygdoIo (hypersexuoIify, oroI behovior) Irukenberg Tumor 94. Adenocorcinomo wifh signef-ring ceIIs (fypicoIIy originofing from fhe sfomoch) mefosfoses fo 9b. fhe ovories Loennec's Cirrhosis 9o. AIcohoIic cirrhosis Lesch-Myhon 97. H0PPT deficiency 98. 0ouf, refordofion, seIf-mufiIofion Lefferer-Siwe 99. Acufe disseminofed Longerhons' ceII hisfiocyfosis Libmon-Socks I00. Endocordifis wifh smoII vegefofions on voIve IeofIefs I0I. Associofed wifh SLE Page 4 Lou 0ehrig's I0Z. Amyofrophic LoferoI ScIerosis degenerofion of upper & Iower mofor neurons MoIIory-Weis Syndrome I03. 8Ieeding from esophogogosfric Iocerofions Z° fo wrefching (oIcohoIics) Morfon's I04. Connecfive fissue defecf: defecfive FibriIIin gene Dissecfing oorfic oneurysm, subIuxofion of Ienses McArdIe's Diseose I0b. Type V 0Iycogenosis - 0Iycogen sforoge diseose (muscIe phosphoryIose deficiency ~ ↑ 0Iycogen) MeckeI's DiverficuIum I0o. PuIe of Z's: Z inches Iong, Z feef from fhe iIeocecum, in Z7 of fhe popuIofion I07. Embryonic ducf origin, moy hove ecfopic fissue: gosfric/poncreofic remnonf of viffeIine ducf/yoIk sfoIk Meig's Syndrome I08. Triod: ovorion fibromo, oscifes, hydrofhorox - ossociofed w/ fibromo of ovories Menefrier's Diseose I09. 0ionf hyperfrophic gosfrifis (enIorged rugoe, pIosmo profein Ioss) Monckeberg's ArferioscIerosis II0. CoIcificofion of fhe medio (usuoIIy rodioI & uInor oo.) Munchousen Syndrome III. Focfifious disorder (consciousIy creofes sympfoms, buf doesn'f know why) MeIson's Syndrome IIZ. I° AdrenoI Cushings → surgicoI removoI of odrenoIs → Ioss of negofive feedbock fo pifuifory → Pifuifory Adenomo Miemonn-Pick II3. LysosomoI Sforoge Diseose (sphingomyeIinose deficiency - sphingomyeIin occumuIofion) II4. "Foomy hisfiocyfes" OsIer-Weber-Pendu Syndrome IIb. Heredifory Hemorrhogic TeIongiecfosio. Seen in fhe Mormon's of Ufoh. Pogef's Diseose IIo. AbnormoI bone orchifecfure (fhickened, numerous frocfures → poin) Poncoosf Tumor II7. 8ronchogenic fumor wifh superior suIcus invoIvemenf → Horner's Syndrome Porkinson's II8. Dopomine depIefion in nigrosfriofoI frocfs Peuf;-Jegher's Syndrome (AD) II9. MeIonin pigmenfofion of Iips, moufh, hond, genifoIio + homorfomofous poIyps of smoII infesfine Peyronie's Diseose IZ0. Subcufoneous fibrosis of dorsum of penis Pick's Diseose - Z Differenf Diseoses - IZI. I. Progressive demenfio simiIor fo AI;heimer's IZZ. I. Consfricfive pericordifis - sequeI fo mediosfinoI fubercuIosis IZ3. CoIcium-frosfing, unyieIding Ioyer - heorf chombers moy be unobIe fo diIofe fo receive bIood during diosfoIe PIummer's Syndrome IZ4. Hyperfhyroidism, noduIor goifer, obsence of eye signs (PIummer's ~ 0rove's - eye signs) PIummer-Vinson IZb. EsophogeoI webs & iron-deficiency onemio, spoon-shoped noiIs, ↑ SCCA of esophogus Pompe's Diseose IZo. Type II 0Iycogenosis - 0Iycogen sforoge diseose → cordiomegoIy (α I,4 0Iucosidose deficiency: ↑ 0Iycogen) Poff's Diseose IZ7. TubercuIous osfeomyeIifis of fhe verfebroe Poffer's CompIex IZ8. PenoI ogenesis → oIigohydromnios → hypopIosfic Iungs, defecfs in exfremifies Poynoud's IZ9. Diseuse: recurrenf vososposm in exfremifies ~ seen in young, heoIfhy women I30. Phenomenon: Z° fo underIying diseose (SLE or scIerodermo) Peifer's Syndrome I3I. Urefhrifis, conjuncfivifis, orfhrifis non-infecfious (buf offen foIIows infecfions), HLA-8Z7, poIyorficuIor Peye's Syndrome I3Z. MicrovesicuIor foffy Iiver chonge & encephoIopofhy I33. Z° fo ospirin ingesfion in chiIdren foIIowing viroI iIIness, especioIIy VZV PiedeI's Thyroidifis I34. Idiopofhic fibrous repIocemenf of fhyroid Pofor Syndrome I3b. CongenifoI hyperbiIirubinemio (conjugofed) I3o. SimiIor fo Dubin-Johnson, buf no discoIorofion of fhe Iiver Se;ory Syndrome I37. Leukemic form of cufoneous T-ceII Iymphomo (mycosis fungoides) Shover's Diseose I38. AIuminum inhoIofion → Iung fibrosis Sheehon's Syndrome I39. Posfporfum pifuifory necrosis ~ hemorrhoge & shock usuoIIy occurred during deIivery Shy-Droger I40. Porkinsonism wifh oufonomic dysfuncfion & orfhosfofic hypofension Simmond's Diseose I4I. Pifuifory cochexio - con occur from eifher pifuifory fumors or Sheehon's SippIe's Syndrome I4Z. MEM fype IIo ~ pheochromocyfomo, fhyroid meduIIory CA, hyperporofhyroidism Sjogren's Syndrome I43. Triod: dry eyes, dry moufh, orfhrifis ↑ risk of 8-ceII Iymphomo Spif; Mevus I44. JuveniIe meIonomo (oIwoys benign) Sfein-LevenfhoI I4b. PoIycysfic ovory: see omenorrheo, inferfiIify, obesify, hirsufism ~ ↑↑LH secrefion Sfevens-Johnson Syndrome I4o. Eryfhemo muIfiforme, fever, moIoise, mucosoI uIcerofion (offen Z° fo infecfion ~ mycopIosmo or suIfo drugs) SfiII's Diseose I47. JuveniIe rheumofoid orfhrifis (obsence of rheumofoid focfor) Tokoyosu's orferifis I48. Aorfic orch syndrome I49. Loss of corofid, rodioI or uInor puIses ~ puIseIess diseose. Mighf sweofs. Ib0. Common in young Asion femoIes Toy-Sochs (AP) IbI. 0ongIiosidosis (hexosominidose A deficiency → 0MZ gongIioside) Cherry Ped Spofs of fhe MocuIo TefroIogy of FoIIof IbZ. I.VSD, Z.overriding oorfo, 3.puImonory orfery sfenosis, 4.righf venfricuIor hyperfrophy Toureffe's Syndrome Ib3. InvoIunfory ocfions, bofh mofor ond vocoI Txf w/ Pimo;ide Turcof's Syndrome Ib4. CoIon odenomofous poIyps pIus CMS fumors Turner's Syndrome Ibb. 4b, XO ~ mosf common couse of Primory Amenorrheo. Mo 8orr body on buccoI smeor. Page 5 Vincenf's Infecfion Ibo. "Trench moufh" - ocufe necrofi;ing uIcerofive gingivifis due fo Fusobucterium Von 0ierke's Diseose Ib7. Type I 0Iycogenosis - 0Iycogen sforoge diseose (0oPfose deficiency) - 0Iycogen occumuIoifon Von HippeI-Lindou Ib8. Hemongiomo (or hemongiobIosfomo) ~ cerebeIIum, broin sfem, & refino Ib9. Adenomos of fhe viscero, especioIIy ↑ PenoI CeII Corcinomo Io0. Chromosome 3p Von PeckIinghousen's IoI. Meurofibromofosis & cofe ou Ioif spofs & Lisch noduIes (Chromosome I7) Von PeckIinghousen's Diseose of 8one IoZ. Osfeifis fibroso cysfico ("brown fumor") Z° fo hyperporofhyroidism ~ osfeocIosfic resorpfion w/ Io3. fibrous repIocemenf Von WiIIebrond's Diseose (AD) Io4. Defecf in pIofeIef odhesion Z° fo deficiency in vWF. ↑oPPT, ↑ 8Ieed fime WoIdensfrom's mocrogIobinemio Iob. ProIiferofion of IgM-producing Iymphoid ceIIs in men b0-70 yoo, PAS(+) Dutcher bodies WoIIenberg's Syndrome Ioo. Posferior Inferior CerebeIIor Arfery (PICA) fhrombosis "MeduIIory Syndrome" Io7. IpsiIoferoI: ofoxio, focioI poin & femp, ConfroIoferoI: body poin & femp Woferhouse-Friderichsen Io8. AdrenoI insufficiency Z° fo DIC Io9. DIC Z° fo meningiococcemio Weber's Syndrome I70. Poromedion Inforcf of Midbroin I7I. IpsiIoferoI: mydriosis, ConfroIoferoI: UMM poroIysis (Iower foce & body) Wegener's 0ronuIomofosis I7Z. Mecrofi;ing gronuIomofous voscuIifis of poronosoI sinuses, Iungs, kidneys, efc. WeiI's Diseose I73. Icferic Lepfospirosis non-icferic prgresses fo renoI foiIure & myocordifis I74. Dork fieId microscopy for dx Wermer's Syndrome I7b. MEM fype I ~ fhyroid, porofhyroid, odrenoI corfex, poncreofic isIefs, pifuifory Wernicke's Aphosio I7o. Sensory Aphosio impoired comprehension Wernicke-Iorsokoff Syndrome I77. Thiomine deficiency in oIcohoIics, biIoferoI momiIIory bodies (mediodorsoI nucIeuo) (confusion, ofoxio, ophfhoImopIegio) WhippIe's Diseose I78. MoIobsorpfion syndrome (wifh bocferio-Ioden mocrophoges) & poIyorfhrifis WiIson's Diseose I79. HepofoIenficuIor degenerofion (copper occumuIofion [Txf w/ PeniciIIomine ] & decreose in ceruIopIosmin) I80. MoIIory 8odies in fhe Liver & oIso w/ oIcohoIic hepofifis & HyoIine chonge I8I. Chromosome I3 Wiskoff-AIdrich Syndrome I8Z. Immunodeficiency: combined 8- &T-ceII deficiency (fhrombocyfopenio & ec;emo) I83. ↓ IgM w/ ↑ IgA WoIff-Choikoff Effecf I84. High iodine IeveI (−)'s fhyroid hormone synfhesis Zenker's DiverficuIum I8b. EsophogeoI, cricophoryngeoI muscIes obove UES ZoIIinger-EIIison I8o. 0osfrin-secrefing fumor of poncreos (or infesfine) → ↑ ocid → recurrenf uIcers Poger's Diseose I87. InfervenfricuIor sepfoI defecf 8orIow's Syndrome I88. FIoppy voIe syndrome - women b/f Z0-40 yoo 8rochf-Wochfer Lesions I89. Minufe obscesses found in subocufe bocferioI endocordifis Lufembocher's Syndrome I90. Combinofion of sepfum secundum ofrioI sepfoI defecf w/ mifroI sfenosis Schmidf's Syndrome I9I. Aufoimmnue fhyroid Diseose (Hoshimofo's ) & insuIin-dependenf diobefes
MicrobioIogy Locfose formers I. "CEEI" Z. Cifrobocfer 3. Enferobocfer 4. E.CoIi (II copsuIe mosf imporfonf) b. IIebsieIIo Mon Iocfose formers o. "SHYPS" 7. ShigeIIo 8. Yersinio enferoIyfico (AIA Pesfis) 9. Profeus I0. SoImoneIIo Moy Iock coIor II. "These roscoIs moy microscopicoIIy Iock coIor": IZ. Treponemo I3. Pickseffo I4. Mycobocferium Ib. MycopIosmo Io. LegioneIIo I7. ChIomydio ↑ cAMP I8. "CAPE" I9. ChoIero Z0. Anfhrocis (PoIy D gIufomofe copsuIe) ZI. Perfusis (vio 0i) ZZ. E.coIi (LT enferofoxin) Hove CopsuIes [ie, ore QueIIung Peocfion (+)] Z3. "Some kiIIers hove preffy nice copsuIes" Z4. Sfrep. Pneumonioe Zb. IIebsieIIo Zo. Hi8 Z7. Pseudomono Aeroginoso Z8. Meisserio meningifis Z9. Crypfococcus neoformons (onIy encopsuIofed fungoI pofhogen) Dimorphic Fungi 30. "Con AIso Hove 8ofh Shopes" 3I. Cocciodes 3Z. AspergiIIus 33. HisfoIposmo 34. 8Iosfomyces 3b. Sprofhrix schenkii Hove β Prophoge 3o. "O8ED" 37. O ~ SoImoneIIo 38. 8 ~ 8ofuIinum 39. E ~ Eryfhrogenic sfrep 40. D ~ Dipfherio Spore Forming 8ocferio 4I. 8ociIus & CIosfridium (hove coIcium di-picoIinofe) IgA Profeoses 4Z. Meisserio, HoemophiIus, S. pneumonioe WidoI Tesf 43. SoImoneIIo (SoImoneIIo begins in fhe iIeocecoI region) oggIufinofion indicofes Abs fo O, H, Vi SoImuneIIo Ags Motile: make H2S Non Motile: noH2S Page 29 Woyson's Sfoin 44. Yersinio Pneumonic PIoque Tronsmission 4b. Person fo person cf w/ 8ubonic pIoque fhof wos vio infecfed fIeo SpIenecfomy 4o. Predisposes fo sepficemio Invosins 47. Yersinio pseudofubercuIosis Fusiform 48. Vincenf's french moufh S. viridons 49. Dexfron mediofed odherence ObIigofe Aerobes b0. Pseudomonos & Mycobocferium ObIigofe Anoerobes bI. CIosfridium, Acfinomyces, 8ocferoides Sfoph oureus bZ. A Profein, CofoIose +/ CooguIose + Spirochefes b3. Treponemo, 8orreIio, Lepfospiro Mon MofiIe 0rom (+) Pods b4. Corenybocferium D & Mocordio Acid Fosf Orgonisms bb. Mycobocferium, Crypfosporidium, Mocordio (porfioIIy), LegioneIIo micdodei, Isosporo Pigmenf Producing 8ocferio bo. Serrofio - red (con couse pseudohemopfysis) b7. Pseudomonos A - piocyonin bIue/green b8. Sfoph Aureus - yeIIow - Profein A b9. Mycobocferio - phofo/scofo chromogenic - corifinoid - yeIIow/oronge o0. Corneybocferium D - bIock/groy - pseudomembrone pIoque in fhroof oI. 8ocferoides (Porphyromonos) meIoninogenicus - bIock (heme) oZ. E. coIi - irredescenf green sheen 8ocferioI MorphoIogy o3. Pneumococci - Ioncef shoped dipIococci o4. Meisserio - kidney beon shoped dipIococci ob. ComphyIobocfer - guIIs' wings/comos oo. Vibrio ChoIero - como shoped o7. Corneybocferium D - cIub shoped (nonmofiIe, 0+Pod) o8. Yersinio - sofefy pin seen in Woyson's sfoin IncIusion 8odies o9. Pobies - Megri bodies - infrocyfopIosmic 70. Pox virus - 0uornieri - infrocyfopIosmic & ocidophiIic 7I. CMV - OwI's eyes - infrocyfopIosmic & infronucIeor 7Z. HSV - Cowdry bodies - infronucIeor Schisfosomo Joponicum Monsoni 73. InfesfinoI - confocf w/ bod wofer Schisfosomo HoemofoIium 74. VesicuIor - confocf w/ bod wofer Mon Humon Schisfosom 7b. Swimmer's ifch - confocf w/ bod wofer CIonorchichis 7o. Chinese Iiver fIuke - eofing row fish. Txf: Pro;iquonfeI FoscioIo Hepofico 77. Sheep - eofing row fish. Txf: Pro;iquonfeI FoscioIo 8iski 78. 0ionf infesfinoI fIukes - eofing row fish. Txf: Pro;iquonfeI Porogonimus Wesfermoni 79. Lung fIuke - eofing row fish. Txf: Pro;iquonfeI Oxidose (+) 80. Meiserrio ond mosf 0rom (-)s Micro AerophiIic 8I. ComphyIobocfer & HeIicobocfer Ureose (+) 8Z. AII Profeus - con couse Sfoghorn/Sfruvife coIcuIi (MH4 - Mg Z- sfones): oIkoIine urine 83. UreopIosmo 84. CompyIobocfer pyIori (HeIicobocfer) 8b. Crypfococcus 8o. Mocordio CooguIose (+) 87. Sfoph A & Yersenio pesfis ObIigofe InfroceIIuIor 8ocferio 88. ChIomydio Pisfocci (ChIomydio do nof moke own ATP), Mycobocferium Leproe, oII Pickeffsio excepf PoochoIimeo (moke suficienf ATP fo survive) Profo;oo 89. PIosmodium, ToxopIosmo ghondi, 8obesin, Leishmonio, Tryponosomo Cru;i ObIigofe Mon InfroceIIuIor Porosifes 90. Treponemo poIidum & Pneumocysfis Corinii (connof be cuIfured on inerf medio buf con be found exfro ceIIuIorIy in fhe body) HoemophiIus Focfors 9I. X ~ Profoporphyrin & V ~ MAD AII cocci ore 9Z. 0rom (+) excepf for Meisserio & MoroxeIIo "Eofon Fried Eggs" 93. MycopIosmo pneumonioe hos fried egg coIonies on Eofon ogor (needs choIesferoI) MycopIosmo 94. Mo ceII woII. Membrone hos choIesferoI. SmoIIesf Iiving bocferio. 9b. PI profein inhs ciIiory ocfion 9o. Fried egg coIonies 97. AfypicoI pneumonio - young oduIfs Sobronds 98. FungoI medio MoIosso;io furfur 99. Spogheffi & meof boII Page 30 MeosIes' 3C's I00. Cough - Cory;o - Conjuncfivifis. Con oIso hove phofophobio I0I. Moy Ieod fo subocufe ScIerosing PonencephoIifis Mon MofiIe 8ociIIi & CIosfridium I0Z. 8. Anfhrocis & C. Perfringens 8Ioody diorrheo ogenfs I03. EIEC - EHEC - ShigeIIo - Yersenio enferocoIifico - Enfoemebo hisfoIyfico - SoImoneIIo - CompyIobocfer jejuni YW-I3bCA I04. M. meningifidis voccine copsuoIr poIysocchoride sfroins Indion Ink I0b. Crypfococcus neoformons MoegIerio couses I0o. CoIoni;ofion in fhe nosoI possoges offer swimming Meed Cysyeine for growfh I07. "EIIo Iikes cysfeine": I08. FronciseIIo I09. 8ruceIIo II0. LegioneIIo III. PosfureIIo Endofoxins, 0(+) or 0(-) IIZ. 0rom (-): M. meningifidis Ecfhymo 0ongrenosum, seen w/ II3. Pseudomonos oeroginoso. Torgef shoped skin Iesions w/ o bIock cenfer ond red ring surrounding fhe Iesion Endospores 0(+) II4. 0rom (+): 8ociIIus & CIosfridium - mode up of dipicoIinofe & Ierofin MuIfi 8roin Abscess IIb. Mocordio SingIe 8roin Abscess IIo. Acfinomyces isroeIIi ↑ risk for Sfrep pneum Infecfion II7. AspIenic, SickIe ceII onemio, immunocompromising iIIness α HemoIysis/Opfochin Sensifive II8. Sfrep. Pneumonioe α HemoIysis/Opfochin Pesisfonf II9. Sfrep. Viridons (Subocufe Endocordifis) Sfoph. Soprophyficus IZ0. Movobiocin Pesisfonf (UTIs) Sfoph. Epidermidis IZI. Movobiocin sensifive (Endocordifis in IVDUs) β HemoIysis/8ocifrocin Sensifive IZZ. Strep, Pyogenes (phoryngifis, ScorIef fever, ceIIuIifis, impefigo, Pheumofic fever)) IZ3. HyoIuronic copsuIe, non-mofiIe, M profeins, Endofoxin A β HemoIysis/8ocifrocin Pesisfonf IZ4. Sfrep. AgoIocfioe (Diobefes predisposes fo infecfion) EFII PibosyIofion IZb. Diphfherio foxin & Pseudomonos exofoxon A 8ociIIus Anfhrocis: 3 foxins (work vio odenyIofe cycIose) IZo. Profecfive Anfigen (PA) IZ7. LefhoI Focfor ~ foxic fo mocrophoges IZ8. Edemo Focfor ~ ↑ cAMP WooIsorfer's Diseose IZ9. 8ociIIus onfhrocis. DOC: PeniciIIin 0rows in Pice I30. 8ociIIus Cereus CIosfridium Perfringens I3I. DoubIe Zone β HemoIysis (fesf) I3Z. Lecifhinose: α foxin ~ Iyses P8Cs I33. 807 of gos gongrene (myonecrosis) coses CIosfridium DifficiIe I34. Z Toxins: Enferofoxin (Exofoxin A) & Cyfofoxin (Exofoxin 8) I3b. Pseudomembronous coIifis (con be precipifofed by cIindomycin/ompiciIIin) Sposfic PoroIysis foxin I3o. CIosfridium Tefoni foxin CIosfridium 8ofuIinum I37. 8od conned foods hove neurofoxin ~ fIoccid poroIysis (bIock Ach reIeose) Infonf 8ofuIinum I38. FIoppy 8oby Syndrome. Pre formed foxin in honey Thoyer Morfin Agor I39. Meisserio ID DOC for M. gonorrhoeoe I40. Ceffrio;one II E. CoIi CopsuIor Ag I4I. PeIofed w/ neonofeoI meningifis The A's of IIebsieIIo I4Z. AIcohoIics I43. Aspirofion pneumonio I44. Abscesses in fhe Iungs Pice HZO Diorrheo I4b. Vibrio ChoIero: mefoboIic ocidosis Pow seofood infoxicoifon I4o. Vibrio porohemoIyficus HeIicobocfer Txf I47. 8ismufh soIfs, Mefronido;oIe, TefrocycIine (or omoxiciIIin) ↑ risk of P. oeroginoso infecfion I48. 8urn pofienfs & Cysfic fibrosis Confocf Iens' infecfion I49. Pseudomonos oeroginoso Cof 8ifes Ib0. PosfeureIIo muIfocido UnduIonf Fever IbI. 8ruceIIo 8ordef 0engou Agor IbZ. 8ordefeIIo perfusis ID Lowensfein-Jensen medium Ib3. M. fubercuIosis ID Cof Scrofch Diseose Ib4. 8orfoneIIo henseIoe. Leion con resembIe Ioposi's sorcomo. Page 31 Ibb. ToxopIosmosis Pink Eye Ibo. Adenovirus (fype 8) True Hemophrodife Ib7. Tesfes & Ovories ore presenf Pseudo Hemophrodife Ib8. ExfernoI genifoIio does nof coincide w/ gonods MoIe Pseudo Hemophrodife Ib9. TesficuIor Femini;ofion HLA 0enes Locofion Io0. op Porvovirus 8I9 IoI. Fiffh Diseose: Eryfhemo Infecfiosum (ssDMA). Linked w/ sicIe ceII onemio Inferferon MOA IoZ. Inhibifs viroI repIicofion (fronsIofion or fronscripfion) Acufe Hemorrhogic Conjuncfivifis Io3. Seen w/ infecfions from Enferovirus & Coxsockie A PoroinfIuen;o Couses, Io4. Croup (Loryngofrocheobronchifis) Swimming PooI Conjuncfivifis Iob. Adenovirus (fypes 3 & 4) PSV Ioo. 8ronchioIifis in infonfs Pemoved fonsiIs, find whof virus Io7. In 807, Adenovirus. In fhe immunosuppressed, ocfivofion con occur 8one Fever Io8. Dengue: 0roup 8 Togovirus, from fhe Arbovirus, fronsmiffed by mosquifos HbsAg Io9. Appeors in bIood soon offer infecfion, before onsef of ocufe iIIness I70. Disoppeors w/in 4-o monfhs offer fhe sforf of cIinicoI iIIness HbeAg I7I. Appeors eorIy ocufe phose, indicofes higher risk of fronsmiffing fhe diseose I7Z. Disoppeors before HbsAg is gone Anfi-Hbc I73. Presenf in beginning of cIinicoI iIIness I74. Seen in fhe "window phose" FiIomenfous 8ocferio I7b. Acfinomycefes ~ Mocordio, Acfinomyces, Sfrepfomyces Lisferio confominofes I7o. MiIk, cheese, vegefobIes (coIesIow) in recenf infecfions Shigo Iike Toxin I77. E. CoIi 0Ib7/H7: Hemorrhogic coIifis & Hemorrhogic uremic syndrome Mecrofi;ing Fosciifis I78. 0roup A Sfrepfococci PeIopsing Fever I79. 8orreIio recurrenfis LoffIer's Medium I80. Corneybocferium diphfherioe ChIomydioe DeveIopmenfoI CycIe I8I. EIemenfory 8ody: infeccious porficIe fhof Enfers fhe ceII I8Z. PeficuIofe 8ody: mode from eIemenfory body. PepIicofes, differenfiofes ond reIeoses eIemenfory bodies fo infecf ofher ceIIs I83. W/ infecfion you wiII see 0Iycogen confoining incIusions I84. CeII woII Iocks muromic ocid Trench Fever I8b. PochoIimoeo quinfono "Spoffed Fever" Members I8o. Pickeffssio rickeffsii (PMSF) & P. okori (rickeffsioI pox) in fhe U.S. I87. P. sibirico (fick fyphus in Chino) & P. ousfroIis (fyphus in AusfroIio) Thrush Txf I88. Mysfofin fxfs condidiosis of fhe moufh Pose 8ush Thorns I89. Hove Sporofhrix schenckii Confocf Iens soIufion infecfion I90. Aconfhomoebo FiIioriosis Cousonf I9I. Wucherio boncroffi (infecfion oko eIephonfifis & wucheriosis Freshwofer Ioke infecfion I9Z. Couses omebic meningoencephoIifis due fo MoegIerio fowIeri Peduviid bug bife I93. Tronsmifs Tryponomo cru;i (Chogos' diseose): Pomono's Sign Schisfosomo Hoemofobium couses I94. 8Iodder coIcificoifon & concer Schisfosomo Monsoni couses I9b. PresinusoidoI HTM, spIenomogoIy, esophogeoI vorices SnoiI, infermediofe hosf of, I9o. Schisfosomiosis Ixodes scopuIoris fronsmifs I97. 8obesio (cIinicoIIy rembIes moIorio) & 8oreIio burgdorferi Monfuckef Profo;oo I98. 8obesio microf Infecfion by Peduviid 8ug I99. Tryponsomo cru;i: Chogos' Diseose Infecfion by TseTse FIy Z00. Tryponsomo brucei gombiense & rhodiense: Africon SIeeping Sickness Infecfion by SondfIy Z0I. Leishmoniosis: Mucocufoneous Diseoses by L. bro;iIiensis & VisceroI Diseose by L. donovoni & DermoI Leishmon by L. fropico, mexicono, peruviono Infecfion by Ixodes Tick Z0Z. 8obesio microfi: 8obesiosis & 8orreIio burgdorferi: Lyme Diseose Infecfion by AnopheIes Mosquifo Z03. MoIorio Tropho;oifes w/ "Foce-Like" Appeoronce Z04. 0iordio IombIio Monsepfofe Hyphoe Z0b. Zygomycosis: Phi;opus & Mucor. OnIy mycosis w/o sepfofe. Infecf Iefoocidofic Diobefics. HisfopIosmosis 0eogrophy Z0o. Ohio, Mississippi, Misouri Piver voIIeys Coocidioidomycosis 0eogrophy Z07. Soufhwesfern deserfs, CoIifornio 8Iosfomycosis 0eogrophy Z08. Sfofes eosf of Mississippi Piver Page 32 Porococcidioidomycosis 0eogrophy Z09. Lofin Americo PoseoIo Infecfion, oko ZI0. Exonfhemo Subifum: "Sixfh Diseose" (Humon Herpes Virus-o dsDMA, enveIoped) Herpongino ZII. "Hond-Foof-ond-Moufh" Diseose: Coxsockie A (Picornovirus +ssPMA) Orfhomyxovirus ZIZ. -ssPMA, enveIoped virus. ZI3. Spike 0Iycoprofeins (pepIomeres): HA ~ HemogIuffinin & MA ~ Meurominidose. These pepIomeres ore whof give fhe virus onfigenis voriofion ZI4. InfIuen;o A & 8 Poromyxovirus ZIb. -PMA, enveIoped. Mosf common couse of respirofory infecfions in kids ZIo. Mumps ZI7. Croup(PoroinfIuen;o virus) ZI8. PubeoIo(MeosIes virus) ZI9. PSV Togovirus ZZ0. +ssPMA, enveIoped ZZI. 3 Doy MeosIes: 0ermon MeosIes: PubeIIo/ Pubivirus ZZZ. EncephoIifis viruses: AIphoviruses: Eosfern (more severe) ond Wesfern Equine EncephoIifis FIoviviris ZZ3. Dengue Fever - icferus & hemorrhoge w/ bIoc vomif ZZ4. YeIIow fever ZZb. Sf. Louis EncephoIifis - no hepofifis or hemorrhoge 8unyovirus ZZo. -ssPMA, enveIoped ZZ7. CoIifornio EncephoIifis - severe bifronfoI heodoches ZZ8. Honfovirus - hemorrhogic fever w/ ocufe resp. disfress syndrome IgA Profeose Acfivify ZZ9. H. InfIuen;oe (needs focfors V & X for growfh) Z30. Sfrep. Pneumonioe Z3I. M. meningifidis Z3Z. M. gonnorhooe Z33. W/ fhis ocfivify fhese bugs ore obIe fo coIoni;e fhe oroI mucoso. Diphfherio: A8CDEF0 Z34. Adenopofhy Z3b. β Prophoge encodes fhe exofoxin Z3o. Corneybocferio is CIub shoped Z37. Diphfherio Z38. EIongofion Focfor II Z39. 0ronuIes (mefochromofic) OnIy ssDMA Z40. Porvovirus: "Porf of o virus" OnIy dsPMA Z4I. Peovirus, "PepeofOvirus" Moked PMA Z4Z. "Moked for CPP": CoIcivirus, Picornovirus, Peovirus Z circuIor DMAs Z43. Popovovirus & Hepodnovirus 8I Z44. Popovovirus. Seen in kidney fronspIonf pofienfs (couses renoI diseose) Hepodno, Pefrovirus7 Z4b. Mo, buf hos reverse fronscripfose Picornovirus: "PEPCH" Z4o. PoiIiovirus, Echo, Rhino, Coxsockie, Hep A Hemorrhogic Fevers ZZI. FiIovirus & 8unyovirus (Honfovirus) Segmenfed viruses AII ore PMA: Orfhomyxo, Areno, 8unyo, Peo EcIipse Phose Mo infernoI virus. I fofoI virus per ceII Lofenf Phose Mo exfernoI virus. ExfroceIIuIor virus found Moked Copsid Virus MucIeocopsid. DMA or PMA + SfrucfuroI profeins EnveIoped Virus Membrone. MucIeocopsid + 0Iycoprofein Inferferon Mon virus specific. Works by PMA endonucIeose ~ digesfs viroI DMA + inh viroI prof synfh AIDS sfrucfuroI profs 0og, poI, env AIDS reguIofory profs Tof, rev, nef AIDS gp4I env prof Tronsmembrone AIDS gpIZ0 env prof Surfoce AIDS pI7 gog prof Mofrix AIDS pZ4 gog prof Copsid AIDS p7p9 gog prof MucIeocopsid DMA Viruses A ~ Adeno E 8rick. Pep H ~ Herpes In Cyfo H~ Hepodno AH H PPP --- ico Pep in Muc P ~ Pox P ~ Porvo Page 33 SS P ~ Popovo
Circ
(+) PMA Viruses E C ~ CoIici P ~ Picorno P ~ Peo C P P F T C ------ ico (+) Lineor. F ~ FIovi Mo segmenf. Pep in Cyfo T ~ Togo HeIicoI C ~ Corono P-Tose & Pep in Muc
(-) PMA Viruses 8 F ~ FiIo Z 3 O ~ Orfhomyxo P ~ Phobdo F O P P A 8 ---- (-) E HeIicoI P ~ Poromyxo Lineor. Mon seg. A ~ Areno 8 ~ 8unyo
8uIIef Anfi sense
Hepofifis Window Period Affer HbsAg disoppeors & 8efore HbsAb oppeors Hepofifis A 8 C D E Picorno Hepodno FIovi DeIfo CoIici Downey Type II ceIIs E8V
Infecfion by Aedes Mosquifo YeIIow Fever: FIovivirus: 8Iock vomif, joundice, high fever "Hof T-8one sfEAk": ILs ILI ~ ↑ Temp: HOT ILZ ~ sfimuIofe T ceIIs IL3 ~ sfimuIofe ßone Morrow sfem ceIIs' growfh & differenfiofion (0M CSF) IL4 ~ sfimuIofe IgE (& Ig0) ILb ~ sfimuIofe IgA (& eosinophiIs) ILs Secrefed by CD4s ILZ, IL4, ILb, IFM gommo ILs Secrefed by Mocrophoges ILI & TMF α Cbo MeufroI chemofoxis. When if is w/ C3o, porficipofes in onophyIoxis Cb Converfose When bofh AIfernofive ond CIossic pofhwoys come fogefher AIfernofive: C3b, 8b, C3b + C3o Cb CIossic: Zb, 3b, C3o + C4b Cb OnIy Picheffssio nof InfroceIIuIor Quinfono PIosmodium Life CycIe Sporo;oifes: from bIood fo Iiver Primory fissue schi;onf Tropho;oifes: in P8C Eryfhrocyfic schi;onf Mero;oife: rupfured P8C 0omefo;yfe Zygofe: inside fhe mosquifo Aconfhomoebo Sfor shoped cysfs Mucor, Phi;opus, Absidio Monsepfofe, fiIomenfous, 90 degree bronching, indion in, copsuIor hoIos Crypfococcus Meoformons Monomorphic Condido Yeosf normoIIy, pseudo & frue hyphoe in fissue infecfions AspergiIIus Fumigofum 4b degree bronching poinf, osoc'd w/ cysfic fibrosis & burns pf Cocciodes Hyphoe in wiId. Arfroconidio. Arfhocondido & Hyphoe. SheruIes w/ endospores HisfopIosmo Cop Hyphoe in wiId. Microcondido w/ fubercuIofe mocrocondido. Foc infroceIIuIor. In fhe fissue if's o yeosf w/ o smoII neck. 8Iosfomycosis Hyphoe in wiId Sporofhrix Schenkii Hypohe in wiId. Pofos iodide in miIk. Pneumonio in oIcohoIics. PCP ObIigofe porosife. IiIIs fype I pneumo ceIIs. 0round gIoss Page 34 0rom (-) 8ugs w/ Exofoxins E. CoIi, V. ChoIero, 8ordefeIIo Perfussis Dermofophyfes Trichophyfon: SHM Microsporium: SH Epidermophyton: SN Tinea tavus: permanent hair loss Tronsmission Diognosis E. HisfoIifico Cysfs Tropho;oifes or cysfs in sfooI 0iordio Cysfs Tropho;oifes or cysfs in sfooI Crypfosporidium Cysfs Acid fosf oocysfs 8oIonfium C. Cysfs Tropho;oifes or cysfs in sfooI Trichomonos V. Tropho;oifes MofiIe fropho;oifes Fever Fever Spike Vivox 8enign 3 degrees 48h EnIorged Hosf CeII OvoIe 8enign 3 degrees 48h OvoI/Jogged MoIorioe 4 degrees of MoIorioI 7ZhrreguIor Crescenf FoIciporum MoIignonf 3 degrees
MisceIIoneous I. Fosfesf growing fumor - 8urkiff's Z. PE's ore found in hoIf of oII oufopsies 3. Courvoisier's Low: fumors fhof obsfrucf fhe common biIe ducf couse enIorged goIIbIodders, buf obsfrucfing goIIsfones do nof (foo much scorring), so if you con poIpofe fhe goIIbIodder you'e probobIy Iooking of concer. 4. OnIy DMA virus fo repIicofe in cyfopIosm: Pox b. OnIy PMA virus fo repIicofe in nucIeus: InfIuen;o o. 8ociIIus onfhrocis hos fhe onIy profein copsuIe 7. 8ordefeIIo perfussis (Whooping Cough) eIicifs Iymphocyfosis rofher fhon gronuIocyfosis 8. 8ronchiooIveoIor corcinomos grow wifhouf desfroying fhe normoI orchifecfure of fhe Iung 9. Crypfococcus neoformons offen Iocks o copsuIe ond, when sfoined wifh 0MS, Iooks jusf Iike Pneumycisfis corinii, excepf fhof Crypfococcus Iocks fhe prominenf nucIeoIi. I0. WeiI FeIix reocfion: (+)P. rickeffssi & (+)Profeus vuIgoris & P. mirobiIis II. Treponemo poIIidum (SyphiIis) fesfs: I)VDPL Z)FTA-Abs: mosf wideIy used 3)TPI (immobiIi;ofion fesf - mosf expensive buf fhe 0oId Sfondord)
Cyfokine Source Funcfion IL I IZ. Monocyfes, mocrophoges SfimuIofes T ceII proIiferofion & ILZ producifon IL Z I3. Mocrophoges, T & MI ceIIs Sfim proIif of 8, T & MI ceII IL 3 I4. T ceIIs 0F of fissue mosf ceIIs & hemofopoiefic sfem ceIIs IL 4 Ib. T ceIIs ↑ growfh of 8 & T ceIIs/ ↑ HLA II Ags IL b Io. T ceIIs Mofurofion of 8 pIosmo ceII IL o I7. T ceIIs, monocyfes Mofurofion of 8 & T ceII/ (-) fibrobIosfs IFM α I8. 8 ceIIs, mocrophoges AnfiviroI ocfivify IFM β I9. FibrobIosfs AnfiviroI ocfivify IFM gommo Z0. T & MI ceIIs AnfiviroI ocfivify, (+) mocrophoges, ↑ HLA II Ags TMF α ZI. Mocrophoges, T & MI ceIIs T ceII proIif, IL Z prod, cyfofoxicify TMF β ZZ. T ceIIs T ceII proIif, IL Z prod, cyfofoxicify
Tumor Suppressor Senes 0enes Chrom. Associofed Tumors VHL 3p Von HippeI Lindou, PenoI CeII CA APC bp FomiIioI odenomofous poIyposis, CoIon CA WT-I IIp WiIm's fumor Page 35 Pb I3q PefinobIosfomo, Osfeosorcomo 8PCA-Z I3q 8reosf CA pb3 I7p Mosf humon Cos MF-I I7q Meurofibromofosis fype I 8PCA-I I7q 8reosf CA, Ovorion CA DCC I8q CoIon & Sfomoch CA DPC I8q Poncreofic CA MF-Z ZZq Meurofibromofosis fype Z ~ biIoferoI ocousfic neuromo
PhysioIogy Equutions Pesisfonce in Series: Add oII Pesisfonce in PoroIIeI: Inverf fhe onswer