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• (LDH) Lactate
dehydrogenase - Total LDH
will begin to rise 2 to 5 days • Myoglobin - early and sensitive
after an MI; the elevation can diagnosis of myocardial infarction
last 10 days. in the emergency department This
o 140-280 U/L small heme protein becomes
abnormal within 1 to 2 hours of
necrosis, peaks in 4-8 hours, and
drops to normal in about 12 hours.
• LDH-1 and LDH-2 LDH o <1
isoenzymes - Compare LDH
1 and LDH 2 levels.
Normally, the LDH-1 value
will be less than the LDH-2. • Troponin Complex - Peaks in 10-24
In the acute MI, however, hours, begins to fall off after 1-2
the LDH 2 remains weeks.
Table of Cardiac markers Typical Marker Values during AMI
Serum
Markers of
Myocardial
Injury
12-
CK/CK-MB 3-8 24-48
16
MB
1-6 4-8 12-48
Isoforms
cTnI:
5-9
Troponin 10- days
3-6
Complex 24 cTnT:
7-14
days