HLA Dictionary

Tissue Antigens ISSN 0001-2815
The HLA dictionary 2008: a summary of HLA-A, -B, -C, -DRB1/3/

4/5, and -DQB1 alleles and their association with serologically
defined HLA-A, -B, -C, -DR, and -DQ antigens
R. Holdsworth1,8,9, C. K. Hurley2,8,10, S. G. E. Marsh3,4,8,10, M. Lau5,8, H. J. Noreen6, J. H. Kempenich7,
M. Setterholm7,10 & M. Maiers7,10
1 Victorian Transplantation and Immunogenetics Service, Australian Red Cross Blood Service, Melbourne, Australia
2 Department of Oncology, Georgetown University Medical Center, Washington, DC, USA
3 Anthony Nolan Research Institute, Hampstead, London, UK
4 UCL Cancer Institute, Royal Free Campus, Hampstead, London, UK
5 UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, Los Angeles, CA, USA
6 Histocompatibility Laboratory, University of Minnesota Medical Center, Fairview, Minneapolis, MN, USA
7 National Marrow Donor Program, Minneapolis, MN, USA
8 WHO Nomenclature Committee for Factors of the HLA system
9 Australian Bone Marrow Donor Registry, NSW, Australia
10 Quality Assurance and IT Working Groups, World Marrow Donor Association, Leiden, The Netherlands
Key words
alleles; antigens; histocompatibility; HLA;
serological equivalents; serology
Correspondence
Rhonda Holdsworth, BSc
Victorian Transplantation and
Immunogenetics Service
Australian Red Cross Blood Service
PO Box 354
South Melbourne
Victoria 3205
Australia
Tel: 161 3 9694 0379
Fax: 161 3 9682 1630
e-mail: rholdsworth@arcbs.redcross.org.au
Received 27 October 2008; accepted 7
November 2008
Abstract
The 2008 report of the human leukocyte antigen (HLA) data dictionary presents
serologic equivalents of HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, and
-DQB1 alleles. The dictionary is an update of the one published in 2004. The data
summarize equivalents obtained by the World Health Organization Nomenclature
Committee for Factors of the HLA System, the International Cell Exchange,
UCLA, the National Marrow Donor Program, recent publications, and individual
laboratories. The 2008 edition includes information on 832 new alleles (685 class I
and 147 class II) and updated information on 766 previously listed alleles (577 class I
and 189 class II). The tables list the alleles with remarks on the serologic patterns and
the equivalents. The serological equivalents are listed as expert assigned types, and
the data are useful for identifying potential stem cell donors who were typed by
either serology or DNA-based methods. The tables with HLA equivalents are
available as a searchable form on the IMGT/HLA database Web site (http://
www.ebi.ac.uk/imgt/hla/dictionary.html).
doi: 10.1111/j.1399-0039.2008.01183.x
The 2008 edition of the human leukocyte antigen (HLA)

data dictionary is the fifth update; previous versions have
been published in 1997, 1999, 2001, and 2004 (14). The
HLA data dictionary is aimed at identifying the serological
types associated with each HLA-A, -B, -C, -DRB1, and
-DQB1 allelic product. The dictionary is a reference to help
with the identification of potential hematopoietic stem cell
(HSC) donors. The serologic equivalents of the DNA-
2009 John Wiley & Sons A/S Tissue Antigens 73, 95170
defined alleles can be used to identify potential donors listed

in unrelated donor registry databases and umbilical cord
banks who have been typed by serology. Although the
majority of laboratories use DNA-based methods for typing
today, there is a significant number of HLA assignments in
registries and banks that have been determined by serologybased methods. For example, in the database of almost 7
million volunteers of the National Marrow Donor Program
95
R. Holdsworth et al.
HLA alleles and serologic types
(NMDP) in the United States, the percent of serologic

assignments for volunteer donors is still significant, with
45% of the HLA-A and -B loci, 31% of the -C locus, 4% of
the -DRB1 locus, and 37% of the -DQB1 locus assignments
defined serologically. The availability of serologic equivalents allows potentially matched volunteers typed by
serology to be matched to DNA-typed patients.
The number of newly identified HLA alleles grows each
year and since the 2004 publication, 832 new HLA alleles
have been added, including 235 HLA-A, 310 -B, 140 -C, 116
-DRB1, 9 -DRB3/4/5, and 22 -DQB1 alleles. Information
has also been updated for 766 previously listed alleles
numbering 158 HLA-A, 303 -B, 116 -C, 133 -DRB1, 13 DRB3/4/5, and 43 -DQB1 alleles. This edition of the
dictionary includes all newly defined four-digit alleles
displayed in the IMGT/HLA database (5) to the end of
July 2007 in Tables 16.
Information for the 2008 edition of the dictionary has
been contributed from several sources. The World Health
Organization (WHO) serological assignment is taken from
the Nomenclature report 2004 (6) and from data submitted
to the WHO Nomenclature Committee for Factors of the
HLA System when a new allele is submitted for consideration. The International Cell Exchange, UCLA program
provides a unique opportunity to obtain the serologic type
of rare and unusual alleles. Updated information for 335
alleles was provided by the Cell Exchange for this dictionary
edition. Results are routinely submitted from laboratories
around the world. Half of the nearly 200 laboratories
actively participating in the Cell Exchange are outside the
United States, with laboratories in Canada, Europe, the
Middle East, Africa, Asia, Australia and New Zealand,
and South America. The serology typing data from this
program continue to enhance the dictionary information.
The NMDP data for 454 alleles have been updated with
serologic typing information. The 13 IHWS data have been
taken from the 2004 edition of the data dictionary. There
have been no further updates on these data. The artificial
neural network (NN) analysis (7) has been rerun to provide
valuable data on the most likely serological result for
a particular allele. The NN analysis now includes data for
alleles of the HLA-C and -DQB1 loci. In addition,
serological typing information has been submitted from
expert laboratories. The serology data from all sources have
been summarized by the authors in the second column of
Tables 16 as the expert assigned type.
WHO nomenclature: allele and serologic

assignments
The 2008 edition of the dictionary contains all alleles from

the IMGT/HLA database in release 2.18.0 July 2007. Only
the four-digit numbering of alleles is listed in the tables
because the fifth and sixth digits (silent substitutions) are
96
not expected to alter the antigenic expression. Nonexpressed alleles with unique four-digit designations are included for completeness. Nonexpressed alleles, which share
a four-digit designation with an expressed allele (e.g.
B*15010102N and B*15010101), have been excluded from
the tables.
The serologic assignment (third column of Tables 16) is
taken from the HLA Nomenclature report 2004 (6).
Serologic specificities of newly identified alleles are only
included when reported by the allele contributors as being
identical or very similar to the standard specificity
associated with the allele group (e.g. A1 associated with
A*01 alleles). Likewise, the contributor may report an allele
to be expressed as a serologically variant antigen. Such
information is included in the nomenclature report under
the heading previous equivalents and is included here in
the Comments column of Tables 16. In some cases, the
serological definition given in the WHO Nomenclature
Report and displayed in the third column has been derived
from the previous versions of the dictionary, as these data
were considered sufficiently compelling to be adopted as the
WHO value. Such instances of dictionary-derived WHO
values are indicated by a footnote in Tables 16.
International Cell Exchange, UCLA
The International Cell Exchange, UCLA provided data

showing serologic equivalents for 49 HLA-A, 128 -B, 35 -C,
88 -DRB1, 8 -DRB3, 3 -DRB4, 5 -DRB5, and 19 -DQB1
alleles. The latest HLA class I analysis has been updated
with the inclusion of data from 136 new samples, cells 1185
1320, from healthy individuals, characterized between
February 2004 and November 2007. Each cell was typed
by an average number of 100 laboratories, ranging from
a low of 83 to a high of 118. The parallel typing for HLA-A,
-B, and -C alleles using DNA-based methods was performed
by an average of 46 laboratories, ranging from 43 to 51
reporting results for the monthly studies.
The HLA class II analysis was updated with the typing
information from 68 B lymphoblastoid cell lines (TER335402) from the same time period, February 2004 through
November 2007. Each cell was typed serologically by an
average number of 13 laboratories, ranging from a low of 8
to a high of 18. The parallel typing for HLA-DRB1, -DRB3,
-DRB4, -DRB5, and -DQB1alleles using DNA-based
methods was performed by an average of 80 laboratories,
ranging from a low of 66 to a high of 87.
HLA serologic equivalents have been analyzed in
heterozygous samples only if the other HLA allelic product
would not interfere with the serologic recognition. The
associated serologic specificities as reported by the participating laboratories are given with the lowest and highest
percentage recognition, shown in brackets in column 4 of
Tables 16.
Expert assigned
A1
Not expressed
A1
A1
Not expressed
A1
A1
A1
A1
A1
Not expressed
Undefined
A1
A1
Not expressed
Not expressed
A1
Not expressed
A1
A1
A1
Not expressed
A1
A1
A1
A1
Not expressed
A2
Low A2
A2
A203/A2
A2
HLA allele
A*0101
A*01010102N
A*0102
A*0103
A*0104N
A*0106
A*0107
A*0108
A*0109
A*0110
A*0111N
A*0112
A*0113
A*0114
A*0115N
A*0116N
A*0117
A*0118N
A*0119
A*0120
A*0121
A*0122N
A*0123
A*0124
A*0125
A*0126
A*0127N
A*0201
A*02010102L
A*0202
A*0203
A*0204
A2
A203
A2
Null
A1
A1b
Null
A1
A1
Null
Null
Null
Null
A1
Null
Null
A2
Low A2
A1
WHO
assigned
10
A2 [99100]a
A2 [100]a
A2 [77]
A2 [64]
A2 [81]
A1 [100]c
A2 [98]
cd
A1 [95]
A1 [94]c
A1 [99]
34a
117a
Assigned
type [%]
NMDP
Cells
tested
A1 [99]
A2 [99100]
A1 [98100]
Assigned type [%]
International Cell
Exchange, UCLA
Table 1 HLA-A alleles and their serologic designationsg
28
472
859
129
33
1
3
6315
5612
Cells
tested
A203
A2
A1
A2
A1
Assignment
IHWS13 data
12
230
113
Cells
tested
A2
A2
Training A2
The allele was used

for training of the
NN A1
NT
Training A1
Training A1
NT
A1
A1
A1
A1
A1
NT
Not assignede
A1
A1
NT
NT
A1
NT
Not assignede
A1
A1
NT
A1
A1
A1
A1
NT
Training A2
Identical to A*0201
Assigned
type >0.55
NN
Significantly reduced
or low cell surface
expression
ihw13: variant
serum pattern
ihw13: very short
A2
NN: A1
NN: A1
Normal A1
Comments
97
98
Expert assigned
A2
A2
A2
A2
A2
A210/A2
A2
A2
A2
A2
Not expressed
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
Not expressed
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
HLA allele
A*0205
A*0206
A*0207
A*0208
A*0209
A*0210
A*0211
A*0212
A*0213
A*0214
A*0215N
A*0216
A*0217
A*0218
A*0219
A*0220
A*0221
A*0222
A*0224
A*0225
A*0226
A*0227
A*0228
A*0229
A*0230
A*0231
A*0232N
A*0233
A*0234
A*0235
A*0236
A*0237
A*0238
A*0239
A*0240
A*0241
A*0242
Table 1 Continued
A2
A2
A2
A2
A2
A210
A2
A2
A2
A2
Null
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
Null
A2
A2
A2
A2
WHO
assigned
A2 [100]
A2 [99100]a
A2 [100]a
A2 [99]
Assigned type [%]
International Cell
Exchange, UCLA
5
47
15
Cells
tested
A2 [81]c
A2 [73]
A2 [100]c
Blank [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [100]c
A2 [67], blank [33]c

A2 [100]c
A2 [81]
A2 [68]
A2 [80]
A2 [100]c
A2 [100]c
A2 [100]c
A2 [74]
A2 [100]c
A2 [100]c
A2 [100]c
Assigned
type [%]
NMDP
462
636
135
7
10
10
228
10
17
7
16
51
1
1
26
21
11
3
1
1
2
7
8
1
3
1
Cells
tested
A2
A2
A2
A2
A2
A2
A2
Assignment
IHWS13 data
10
24
17
17
1
Cells
tested
Training A2
Training A2
Training A2
A2
A2
A2
A2
A2
A2
A2
NT
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
NT
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
Assigned
type >0.55
NN
Normal A2
Normal A2
Normal A2
Normal A2
ihw13: short A2
Comments

Expert assigned
Not expressed
A2/blank
A2
A2
A2
A2
A2
A2
A2
A2
Not expressed
A2
A2/A28
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2/A19
A2
A2
A2
A2
A2
A2
A2
A2
A2
HLA allele
A*0243N
A*0244
A*0245
A*0246
A*0247
A*0248
A*0249
A*0250
A*0251
A*0252
A*0253N
A*0254
A*0255
A*0256
A*0257
A*0258
A*0259
A*0260
A*0261
A*0262
A*0263
A*0264
A*0265
A*0266
A*0267
A*0268
A*0269
A*0270
A*0271
A*0272
A*0273
A*0274
Table 1 Continued
A2/19
A2
A2
A2
A2
A2
A2
A2
A2
A2
Null
A2
A2
Null
A2
WHO
assigned
Assigned type [%]
International Cell
Exchange, UCLA
Cells
tested
1
1
A2 [100]c
A2 [100]c
cd
6
2
Cells
tested
A2 [100]c
Blank [100]c
A2 [100]c
Assigned
type [%]
NMDP
A2
Assignment
IHWS13 data
Cells
tested
A2
A2
Not assignede
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
NT
A2
Not assignede
A2
A2
A2
A2
A2
A2
A2
A2
NT
A2
A2
A2
A2
A2
Assigned
type >0.55
NN
NN: A74
A2 variant; A2x69
variant
NN: A2, A28, A69

Short A2
A2x9, few A23 1 24

sera reactive
Normal A2. The HLA
club cell exchange:
nine laboratories
performing serology
Comments
99
100
Expert assigned
A2
A2
A2
Undefined
A2
A2
A2
Not expressed
Not expressed
A2
A2
A2
A2
Not expressed
A2
A2
A2
A2
A2
Not expressed
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
Not expressed
HLA allele
A*0275
A*0276
A*0277
A*0278
A*0279
A*0280
A*0281
A*0282N
A*0283N
A*0284
A*0285
A*0286
A*0287
A*0288N
A*0289
A*0290
A*0291
A*0292
A*0293
A*0294N
A*0295
A*0296
A*0297
A*0299
A*9201
A*9202
A*9203
A*9204
A*9205
A*9206
A*9207
A*9208
A*9209
A*9210
A*9211
A*9212
A*9213N
Table 1 Continued
A2
A2
A2
Null
Null
Null
A2
A2
Null
A2
A2
A2
Null
WHO
assigned
Assigned type [%]
International Cell
Exchange, UCLA
Cells
tested
A2 [100]c
A2 [100]c
Assigned
type [%]
NMDP
Cells
tested
Assignment
IHWS13 data
Cells
tested
A2
A2
A2
Not assignede
A2
A2
A2
NT
NT
A2
A2
A2
A2
NT
A2
A2
A2
A2
A2
NT
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
NT
Assigned
type >0.55
NN
NN: A69, A28
Comments

Expert assigned
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
Not expressed
A2
A3
Not expressed
A3
Not expressed
A3
A3/blank
A3/blank
A3
A3
A3
A3/blank
Not expressed
A3
A3
A3
A3
A3
A3
HLA allele
A*9214
A*9215
A*9216
A*9217
A*9218
A*9219
A*9220
A*9221
A*9222
A*9223
A*9224
A*9225N
A*9226
A*0301
A*03010102N
A*0302
A*0303N
A*0304
A*0305
A*0306
A*0307
A*0308
A*0309
A*0310
A*0311N
A*0312
A*0313
A*0314
A*0315
A*0316
A*0317
Table 1 Continued
Null
Null
A3
Null
A3
Null
A3
A3
WHO
assigned
A3 [99100]
44
Cells
tested
A3 [98100]a
Assigned type [%]
International Cell
Exchange, UCLA
cd
A3 [75]c
A3 [100]c
Blank [100]c
cd
A3 [99]
A3 [78]
Assigned
type [%]
NMDP
4
4
1
3504
342
1
5
Cells
tested
A3/blank
A3
A3
A3
Blank
Assignment
IHWS13 data
106
Cells
tested
NT
A3
A3
A3
A3
A3
A3
A3
A3
A3
A3
A3
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
A2
NT
A2
Training A3
NT
Training A3
NT
A3
A3
Assigned
type >0.55
NN
A3 sera negative, only

A3 1 30 1 31 1 33
monoclonal
antibodie positive
ihw13: only reactive

with some A3 1 11
and A3 1 19 1 34
sera; normal A3
ihw13: very short A3
Comments
101
102
Expert assigned
Undefined
A3
A3
Not expressed
A3
A3
A3
A3
A3
A3
A3
A3
A3
A11
A11
A11
A11
A11
A11
A11
A11
A11
A11
Undefined
A11
A11
A11
A11
A11
Undefined
Undefined
A11
A11
Not expressed
A11
HLA allele
A*0318
A*0319
A*0320
A*0321N
A*0322
A*0323
A*0324
A*0325
A*0326
A*0327
A*0328
A*0329
A*0330
A*1101
A*1102
A*1103
A*1104
A*1105
A*1106
A*1107
A*1108
A*1109
A*1110
A*1111
A*1112
A*1113
A*1114
A*1115
A*1116
A*1117
A*1118
A*1119
A*1120
A*1121N
A*1122
Table 1 Continued
A11
A11
A11
A11
A11
A11
A11
A11
A11
Null
A11
A3
Null
A3
A11
A11
A11
A11
WHO
assigned
A11 [99100]a
A11 [99]
A11 [6369]
Assigned type [%]
International Cell
Exchange, UCLA
77
1
Cells
tested
2530
42
17
8
5
2
1
1
A11 [80]c
A11 [100]c
A11 [100]c
Blank [100]c
A11 [100]c
Cells
tested
A11 [99]
A11 [76]
A11 [82]c
A11 [75], blank [25]c
Assigned
type [%]
NMDP
A11
A11
A11
Assignment
IHWS13 data
118
8
1
Cells
tested
A11
A11
A11
A11
A10
Not assignede
A11
A11
A11
A11
A11
Not assignede
Not assignede
A11
A11
NT
A11
A11
A1
A3
A3
NT
A3
A3
A3
A3
A3
A3
A3
A3
A3
Training A11
A11
A11
A11
Assigned
type >0.55
NN
NN: A11
NN: A11
NN: A11
Normal A11
Short A11
Short A11, like A11.2
Normal A11
Short A11
Short A11; normal

A11
Short A11; 3/31 A11
sera reactive
ihw13: short A11
Comments

Expert assigned
A11
A11
A11
A11
Undefined
A11
A11
A11
A11
A11
A23
A23
A23
A23
A23
A23
Not expressed
Not expressed
A23
A23
Not expressed
A23
A23
A23
A23
A23
A24
Low A24
A2403/A24
A24
HLA allele
A*1123
A*1124
A*1125
A*1126
A*1127
A*1128
A*1129
A*1130
A*1131
A*1132
A*2301
A*2302
A*2303
A*2304
A*2305
A*2306
A*2307N
A*2308N
A*2309
A*2310
A*2311N
A*2312
A*2313
A*2314
A*2315
A*2316
A*2402
A*24020102L
A*2403
A*2404
Table 1 Continued
A24(9)
A2403
Null
Null
Null
A23(9)
A24(9)
Low A24(9)
A11
A23(9)
A23(9)b
WHO
assigned
A24 [6668], A2403

[2931]a
A24 [97100]
A24 [05]a
A23 [95100]a
Assigned type [%]
International Cell
Exchange, UCLA
10
99a
3
29
Cells
tested
A24 [62], blank [25],

A2403 [13]c
282
3098
A23 [100]c
A24 [97], A2403 [1]
A24 [55], blank [20],

A9 [4], A2403 [1]
5119
5
1
Cells
tested
A11 [100]c
A23 [95], A24 [1]

A23 [100]c
A9 [100]c
Assigned
type [%]
NMDP
A24
A24
Blank
A23
A23
Assignment
IHWS13 data
146
1
42
Cells
tested
A9
A24
A23
A23
NT
NT
A23
A23
NT
A23
A23
A23
A23
A23
Training A9, A24
Identical to A*2402
A11
A11
A11
A11
Not assignede
A11
A11
A11
A11
A11
Training A9, A23
A23
A23
A23
Assigned
type >0.55
NN
or low cell surface
expression
ihw13: short A24,
negative with A9 1
80 (11) sera
ihw13: short A23,

negative with A9 1
80 (11) sera
NN: A11, A1
Comments
103
104
A24
A24
A24
Not expressed
A2403/A24
Not expressed
A24
A24
A24
A24
A24/A3
A9
A24
A24/A9
A24
A*2406
A*2407
A*2408
A*2409N
A*2410
A*2411N
A*2413
A*2414
A*2415
A*2417
A*2418
A*2419
A*2420
A*2421
A*2422
A24
A9
A24
A24
A24
A9
A24
A24
A24
A24
A2403/A24
A9
A*2405
A*2423
A*2424
A*2425
A*2426
A*2427
A*2428
A*2429
A*2430
A*2431
A*2432
A*2433
Expert assigned
HLA allele
Table 1 Continued
A2403
A24(9)b
A24(9)
A2403
A9
A9
A24(9)b
A24(9)
Null
A24(9)
A24(9)
A24(9)b
A24(9)/A3
Null
A2403
A24(9)
A24(9)
A24(9)
A9
WHO
assigned
A24 [99100]a
Blanka
21
Cells
tested
A23 [6770], A24

[1419]a
A24 [99100]a
Assigned type [%]
International Cell
Exchange, UCLA
11
13
2
2
1
4
4
A24 [83]c
A24 [100]c
A24 [100]c
A24 [100]b
A24 [50], A9 [50]c

A24 [100]c
A24 [100]c
A24 [100]c
2
1
11
11
A24 [100]c
A24 [82]c
A24 [82]c
cd
2
32
Blank [100]c
A24 [42], A9 [9], blank
[16], A2403 [3]
Blank [100]c
20
3
320
30
Cells
tested
A24 [67], blank [33]c

A24 [59]
A24 [47], blank [26]
A24 [45], A23 [50]
Assigned
type [%]
NMDP
A24
A24
A24
A24
A24
A24
A24
A24
Assignment
IHWS13 data
5
17
Cells
tested
A24
A9f
A24
A24
A24
Not assignede
A24
A24
A24
A24
A24
A24
A24
A24
A24
NT
A24
A24
A24
A24
A9f
NT
A24
A24
Training A9, A24
A24
A24
Assigned
type >0.55
NN
A2403
ihw13: short A24

NN: A9, A24, A2
A9variant; A24 sera

negative
ihw13: short A24,
negative with A9 1
80 (11) sera; A2403
like
A2403
NN: A23
ihw13: short A24

A2403x3; short A24
with most A3 and
A9 reactive; NN:
A24
Very short A9
A2403; ihw13: short

A24
Short A24, similar to

A2403
Comments

Expert assigned
A24
A24
Not expressed
A24
A24
A24
Not expressed
A24
A24
A24
A9
Not expressed
A24
A24
Not expressed
A24
A24
A24
A24
A24
A24
A24
A24
A24
A24
A24
Not expressed
A24
A24
A24
A24
A24
A24
A24
A24
A24
A24
HLA allele
A*2434
A*2435
A*2436N
A*2437
A*2438
A*2439
A*2440N
A*2441
A*2442
A*2443
A*2444
A*2445N
A*2446
A*2447
A*2448N
A*2449
A*2450
A*2451
A*2452
A*2453
A*2454
A*2455
A*2456
A*2457
A*2458
A*2459
A*2460N
A*2461
A*2462
A*2463
A*2464
A*2465
A*2466
A*2467
A*2468
A*2469
A*2470
Table 1 Continued
Null
A24
Null
A24(9)
Null
Null
A24(9)
Null
WHO
assigned
A24 [9497]a
Assigned type [%]
International Cell
Exchange, UCLA
Cells
tested
A24 [100]c
Assigned
type [%]
NMDP
Cells
tested
Assignment
IHWS13 data
Cells
tested
A24
A24
NT
A24
A24
A24
NT
A24
A24
A24
A9f
NT
A24
A24
NT
A24
A24
A24
A24
A24
A24
A24
A24
A24
A24
A24
NT
A24
A24
A24
A24
A24
A24
A24
A24
A24
A24
Assigned
type >0.55
NN
NN: A24
Comments
105
106
A26
A10
Not expressed
A26
A26
A26
A10
A*2610
A*2611N
A*2612
A*2613
A*2614
A*2615
A24
A24
A24
A24
A24
A24
A24
A24
A24
A25
A25
A25
A25
A25
A25
A26
A26
A26
A26
A26
A26
A26
A26
A*2471
A*2472
A*2473
A*2474
A*2475
A*2476
A*2477
A*2478
A*2479
A*2501
A*2502
A*2503
A*2504
A*2505
A*2506
A*2601
A*2602
A*2603
A*2604
A*2605
A*2606
A*2607
A*2608
A*2609
Expert assigned
HLA allele
Table 1 Continued
Null
A10b
A10
A26(10)b
A24(9)
A24(9)
A25(10)
A25(10)b
A26(10)
A26(10)
A26(10)
A26(10)
A26(10)
A26(10)
A26(10)
A26(10)
WHO
assigned
A25 [9499]
A26 [9597]a
A26 [9197]a
A26 [9298]a
Assigned type [%]
International Cell
Exchange, UCLA
6a
27
3
11
Cells
tested
A26 [75], A34 [25]c

A26 [100]c
A26 [33], A10 [33],

A34 [33]c
A25 [95], A10 [2]

A25 [88]c
A25 [100]c
A2 [100]c
A26 [97], A10 [2]

A26 [81]
A26 [68], A10 [8]
A10 [50], blank [50]c
A26 [90], A25 [10]c
A26 [100]c
A26 [100]c
A26 [95]
Assigned
type [%]
NMDP
4
3
1375
8
2
1730
31
38
2
10
1
1
65
Cells
tested
A10
47
2
5
A26
A26
A26
A26
A26
18
1
Cells
tested
A25
A25
Assignment
IHWS13 data
NT
A26
A26
A26
A26
A26
A26
A24
A24
A24
A24
A24
A24
A24
A24
A24
Training A10, A25
A25
A25
A25
A25
A25
Training A10, A26
Training A10, A26
Training A10, A26
A26
A26
A26
Not asssignede
A26
Assigned
type >0.55
NN
ihw13: only few A10

sera reactive, may
be typed as blank; A
blank
NN: A66
Short A26, A10

variant
NN: A43, A10, A26

ihw13: short A26,
similar to A*2603;
normal A26
ihw13: short A26
ihw13: short A26
Normal A25
Comments

Expert assigned
A26
A26
A10
Undefined
A26
A26
A26
A26
A26
Not expressed
A26
A26
A26
A26
A26
A26
A26
A26
A26
A26
A29
Not expressed
A29
A29
A29
A29
A29
A29
Not expressed
A29
A29
A29
A29
Undefined
Undefined
A29
A29
HLA allele
A*2616
A*2617
A*2618
A*2619
A*2620
A*2621
A*2622
A*2623
A*2624
A*2625N
A*2626
A*2627
A*2628
A*2629
A*2630
A*2631
A*2632
A*2633
A*2634
A*2635
A*2901
A*29010102N
A*2902
A*2903
A*2904
A*2905
A*2906
A*2907
A*2908N
A*2909
A*2910
A*2911
A*2912
A*2913
A*2914
A*2915
A*2916
Table 1 Continued
A26(10)
A26(10)
Null
A10
A26(10)
A29(19)
Null
A29(19)
Null
A29(19)
A29(19)
WHO
assigned
A29 [98]a
A29 [98100]a
Assigned type [%]
International Cell
Exchange, UCLA
17
Cells
tested
Cells
tested
1
115
1488
4
1
Assigned
type [%]
A26 [100]c
Blank [100]c
A29 [96]
A29 [99]
A29 [100]c
A29 [100]c
A29 [100]c
NMDP
A29
A29
Assignment
IHWS13 data
10
28
Cells
tested
A26
A26
A10f
Not assignede
A26
A26
A26
A26
A26
NT
A26
A26
A26
A26
A26
A26
A26
A26
A26
A26
Training A29
NT
Training A29
A29
A29
A29
A29
A29
NT
A29
A29
A29
A29
Not assignede
Not assignede
A29
A29
Assigned
type >0.55
NN
NN: A32, A29

NN: A29, A30
NN: A26
NN: A43, A10
Comments
107
108
Expert assigned
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A30
A31
A31
A31
A31
A31
A31
Undefined
HLA allele
A*3001
A*3002
A*3003
A*3004
A*3006
A*3007
A*3008
A*3009
A*3010
A*3011
A*3012
A*3013
A*3014L
A*3015
A*3016
A*3017
A*3018
A*3019
A*3020
A*3021
A*3022
A*3101
A*3102
A*3103
A*3104
A*3105
A*3106
A*3107
Table 1 Continued
A31 [9498]a
A31(19)b
A31(19)
A31(19)
A30 [9798]a
A30 [96100]a
A30 [97100]
Assigned type [%]
A30(19)
A30(19)
A30(19)
A31(19)
A30(19)
Low A30(19)
A30(19)
A30(19)
A30(19)
A30(19)
WHO
assigned
International Cell
Exchange, UCLA
23
17
25
Cells
tested
A31 [90], A30 [3],

A19 [1]
A31 [100]c
A31 [100]c
A30 [100]c
A30 [100]c
A30 [100]c
cd
A30 [89], A31 [3],

blank [3], A19 [1]
A30 [93], A31 [2],
A19 [1]
A30 [83], blank [17]c
A30 [94]
Assigned
type [%]
NMDP
17
2
3517
10
6
85
1
2
2124
2895
Cells
tested
A31
A30
A30
A30
A30
Assignment
IHWS13 data
58
25
28
Cells
tested
A31
A31
A31
A31
A31
Not assignede
A30
A30
A30
A30
A30
A30
A30
A30
Training A31
A30
A30
A30
A30
A30
A30
Training A30
A30
A30
A30
A30
Training A30
Training A30
Assigned
type >0.55
NN
NN: A32, A23, A9
or low cell surface
expression
ihw13: very short

A30, only broad
A19 sera reactive
Comments

Expert assigned
A31/A24
A31
A31
A31
A31
A31
Not expressed
A31
A31
A31
A31
A32
A32
A32
A32/A3
A32
A32
A32
A32
A32
A32
A32
A32
A32
A32
A32
A33
A33
A33
A33
HLA allele
A*3108
A*3109
A*3110
A*3111
A*3112
A*3113
A*3114N
A*3115
A*3116
A*3117
A*3118
A*3201
A*3202
A*3203
A*3204
A*3205
A*3206
A*3207
A*3208
A*3209
A*3210
A*3211Q
A*3212
A*3213
A*3214
A*3215
A*3301
A*3303
A*3304
A*3305
Table 1 Continued
A33(19)
A33(19)
A32(19)
A33(19)
A31(19)
A31(19)
Null
A32(19)
A32(19)
WHO
assigned
10a
36
A33 [95100]a
20
Cells
tested
A33 [97100]
A32 [9799]a
Assigned type [%]
International Cell
Exchange, UCLA
3441
3
3
8
A31 [100]c
A32 [94]
A32 [100]c
A32 [67], blank [33]c
A3 [75], A19 [13],
A32 [13]c
A32 [100]c
A33 [87], A19 [3],

blank [4]
A33 [95], A34 [1]
A33 [50], blank [50]c
A33 [92]c
887
2
13
687
1
2
A32 [100]c
A32 [100]c
A32 [100]c
Cells
tested
Assigned
type [%]
NMDP
A33
A33
A33
A32
A3204
Assignment
IHWS13 data
27
19
50
Cells
tested
Training A33
A33
A33
A32
A32
A32
A32
Training A33
A32
A32
A32
A32
A32
A32
A32
A31
Not assignede
A31
A31
A31
NT
A31
A31
A31
A31
Training A32
Not assignede
A32
Not assignede
Not assignede
Assigned
type >0.55
NN
ihw13: short A33
Not expected to be
expressed
A3 with most A32

sera reactive
(ihw13); NN: A32,
A3
NN: A32
A31x24; previously
A*2416; NN: A23,
A9, A32
Bw4 motif present
NN: A32
Comments
109
110
Expert assigned
A33
A33
Undefined
Undefined
A33
A33
A33
Undefined
A34
A34
A34
A34
A34
A10
A34
A34
A36
A36
A36
A36
A43
HLA allele
A*3306
A*3307
A*3308
A*3309
A*3310
A*3311
A*3312
A*3313
A*3401
A*3402
A*3403
A*3404
A*3405
A*3406
A*3407
A*3408
A*3601
A*3602
A*3603
A*3604
A*4301
Table 1 Continued
A36
A36b
A43
A36
A34(10)
A34(10)
A33(19)
A19
A34(10)
WHO
assigned
A36 [8593], A1 [58]a
11
A34 [9295]a
30
Cells
tested
A34 [9398]a
Assigned type [%]
International Cell
Exchange, UCLA
A10 [100]c
A36 [68], A1 [16],
blank [6]
A26 [50], A10 [13],

A34 [13], A19 [13],
blank [13]c
A34 [67], A26 [10],

A10 [5], A66 [4],
A33 [2], blank [7]
A34 [89], A33 [4], A26
[3], A10 [2]
cd
Assigned
type [%]
NMDP
1
807
996
269
Cells
tested
A36
A36
A34
A34
A34
Assignment
IHWS13 data
11
25
Cells
tested
A36
A36
A36
Training A43
A34
A10f
A34
A34
Training A36
A34
A34
Training A10, A34
A33
A33
Not assignede
Not assignede
A33
A33
A33
Not assignede
Training A10, A34
Assigned
type >0.55
NN
NN: A34
ihw13: short A34,

with some A11 and
A19 sera reactive;
A34 variant with
some A10 sera
reactive
NN: A33
ihw13: distinct
pattern from
A*3402
ihw13: distinct
pattern from
A*3401
NN: A31, A33

NN: A31, A33
Comments

Expert assigned
A66
A66
A10
A66
A26
A66
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
Not expressed
A28
A68
A68
A68
A68
HLA allele
A*6601
A*6602
A*6603
A*6604
A*6605
A*6606
A*6801
A*6802
A*6803
A*6804
A*6805
A*6806
A*6807
A*6808
A*6809
A*6810
A*6811N
A*6812
A*6813
A*6814
A*6815
A*6816
Table 1 Continued
Null
A28
A68(28)
A68(28)
A28b
A68(28)
A68(28)
A68(28)b
A68(28)
A66(10)
A68(28)
A10
A66(10)
A66(10)
WHO
assigned
A68 [3845], A28 [53]
A68 [5368], A28

[3145]a
A68 [5565], A28
[3243]a
A68 [4766], A28
[3448]a
A6602 [3565],
A66 [1542], A34
[718], A10 [4]a
A66 [3759], A6601

[2242], A26 [15
18], A10 [27]a
Assigned type [%]
International Cell
Exchange, UCLA
16
15
34
14
Cells
tested
2
1
2
1
2
A28 [50], A68 [50]c

Blank [100]c
A28 [100]c
A68 [100]c
Blank [50], A1 [50]c
4
59
A28 [75], A68 [25]c

A28 [53], A68 [29]
A28 [50], blank [50]c
202
2327
2736
28
205
799
Cells
tested
A28 [72], A68 [19],

A69 [1]
A28 [63], A68 [28]
A66 [38], A34 [27],

A10 [10], A74 [5],
A26 [4]
A66 [32], A34 [18],
A10 [7], A26 [7]
A26 [100]c
A28 [63], A68 [27]
A26 [61], A66 [20],

A34 [8], A10 [3],
A25 [1]
Assigned
type [%]
NMDP
A28
A28
A68
A68
A68
A66
A66
Assignment
IHWS13 data
18
49
19
Cells
tested
NT
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
Training A28, A68
A66
A26
A66
Training A28, A68
Short A28
ihw13: possibly A68,

but cell also A2
positive

but cell also A2
positive
Short A10; NN: A26
A10f
A66
ihw13: A6601
pattern different
from A6602;
reactive with A34 1
66 sera
ihw13: A6602, short
A66
Comments
Training A10, A66
Assigned
type >0.55
NN
111
112
Expert assigned
A68
Not expressed
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A69
A74
A74
A74
A74
A74
A74
A74
A74
HLA allele
A*6817
A*6818N
A*6819
A*6820
A*6821
A*6822
A*6823
A*6824
A*6825
A*6826
A*6827
A*6828
A*6829
A*6830
A*6831
A*6832
A*6833
A*6834
A*6835
A*6836
A*6837
A*6838
A*6839
A*6840
A*6901
A*7401
A*7402
A*7403
A*7404
A*7405
A*7406
A*7407
A*7408
Table 1 Continued
A74(19)
A74(19)
A74(19)
A74(19)
A74(19)
Null
A28
A68(28)
A68(28)
A69(28)
A28
WHO
assigned
A74 [8991]
A69 [4070], A28

[3349]a
A74 [7295]a
Assigned type [%]
International Cell
Exchange, UCLA
13
Cells
tested
c
A28 [100]c
A68 [100]c
A28 [100]c
A28 [56], A69 [7],

A2 [6], A68 [3]
A74 [40], A19 [11],
blank [36]
Blank [50], A74 [17],
A33 [17], A31 [17]c
Blank [72], A74 [17]
A74 [100]c
Blank [100]c
A74 [100]c
A28 [100]
Assigned
type [%]
NMDP
A74
A74
6
29
1
1
1
A74
A69
A28
Assignment
115
289
Cells
tested
IHWS13 data
11
Cells
tested
A74
A74
A74
A74
A74
A74
A74
Training A74
NT
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A68
A28f
A68
A68
A68
A68
Training A28, A69
A68
Assigned
type >0.55
NN
NN: A68

but cell also A2
positvie
Comments

National Marrow Donor Program

Assignments made using the expectation
maximization algorithm
9
A80
Blank [77], A80 [10],

A36 [2], A1 [1]
Undefined
A74
Not expressed
A80
A*7410
A*7411
A*7412N
A*8001
Null
A80
A80 [6888], A36

[03]
11
cd
505
A74 [33], A33 [33],

blank [33]c
A74
A*7409
Cells
tested
Assignment
Expert assigned
HLA allele
WHO
assigned
Assigned type [%]
Cells
tested
Assigned
type [%]
Cells
tested
IHWS13 data
NMDP
International Cell
Exchange, UCLA
Table 1 Continued
Not assignede
A74
NT
Training A80
113
A74
Assigned
type >0.55
The 2008 data set includes only those typings from US

volunteer donors where both serologic and allele-level results
have been reported for the HLA-A, -B, -C, -DRB1, or -DQB1
loci. As in past versions of the dictionary, the expectation
maximization (EM) algorithm was used to obtain the correlation between alleles and serologic assignments. Readers
are referred to previous versions of the dictionary that describe the use of the EM algorithm and the nuances of the data.
In this version, data for alleles serologically typed in 20 or
more donors (cells tested) have not been updated and
remain the same as that shown in the 2004 dictionary (4).
For these alleles, we believe that adequate data have been
accumulated to define the serologic assignments.
A subset of the EM data including the alleles with counts of
less than 20 in the last dictionary version plus newly described
alleles was analyzed. The EM algorithm provides an unbiased
assignment of serologic specificities using information from
all cells carrying the allele in question. In addition, experts
reviewed the serologic assignments for all cells carrying an
allele in this category and assigned serologic specificities.
Uninformative cells were eliminated and known serologic
cross-reactivity was considered in the assignment. The
information from the EM algorithm and the results from
the review were compared and final serologic assignments
were made. The table shows the predicted serologic assignments and the percent of informative individuals carrying
those assignments. The percentages listed in the table are
derived from the review of typings as described above; this
differs from previous years in which the percentages were
derived from the EM algorithm. This change will better
reflect the serologic assignment of these less frequent alleles.
In the EM algorithm, percent assignments are skewed by cells
carrying a second more common allele with the same
serologic assignment. For example, cells carrying both
A*0201 and A*0208 frequently appear. The EM assignment
is influenced by the more common A*0201 allele resulting in
a lower percent assignment for A*0208 (78%). Expert review
eliminated these uninformative cells (i.e. carrying both
A*0201 and A*0208) resulting in an A2 assignment for
A*0208 of 100%.
The information for 454 alleles, including 122 HLA-A,
200 -B, 50 -C, 73 -DRB1, and 9 -DQB1, was reviewed and
updated. The reviewed and updated alleles are indicated by
a footnote in the tables. If an allele appears five times or less,
the serologic assignment(s) should be considered as only an
approximation of the serologic reactivity of the resultant
antigen. It should be noted that the number of individuals
carrying each allele shown in the tables might not be the
total number of volunteer donors carrying the allele in the
NN
NT, not tested; NN, neural network; HLA, human leukocyte antigen; WHO, World Health Organization; NMDP, National Marrow Donor Program.
Updated International Cell Exchange, UCLA.
b
WHO assignment based on dictionary data.
c
Updated NMDP data. In some cases, the information reported in previous dictionaries has changed. Cells have been excluded from this study in some cases because their HLA typing has changed.
d
The allele has been identified but serology not informative.
e
Not assigned; see comment column for predictions >0.20.
f
If a primary specificity is provided by the NN, other specificities >0.4 are shown in the comments column.
g
Ref 1328, 61.
ihw13: difficult to type

next to A1 or A24
NN: A74
Comments
114
Expert
assigned
B7
B703/B7
B7
B7
B7
B7
B7
B7
B7
B7
B7
B7/blank
B7
B7
B7
B7
B7
B7/42
B7/blank
B7
B7
B7
B7
B7
B7
Undefined
B7
HLA allele
B*0702
B*0703
B*0704
B*0705
B*0706
B*0707
B*0708
B*0709
B*0710
B*0711
B*0712
B*0713
B*0714
B*0715
B*0716
B*0717
B*0718
B*0719
B*0720
B*0721
B*0722
B*0723
B*0724
B*0725
B*0726
B*0727
B*0728
B7
B7
B7
B7
B7
B7c
B7
B7c
B7c
B7
B7
B7
B7
B7
B7c
B7
B703
WHO
assigned
B7 [9798]
4
4
32
B7 [98100]a
B7 [9197]a
B7 [9495]
Cells tested
Assigned type [%]
Table 2 HLA-B alleles and their serologic designationsg
B7 [100]b
bd
B7 [100]b
B7 [50], B60 [50]b
8
12
5
3
10
1
B7 [100]b
B7 [92]b
B7 [100]b
Blank [100]b
B7 [100]b
B7 [100]b
B42 [100]b
44
42
23
15
10,841
17
Cells
tested
B7 [89]
B7 [95]
B7 [96]
B7 [93]b
B7 [98]
B7 [94]b
Assigned type [%]
NMDP
B7
B7
B7
B7
B7
B7
B7
B703, B7, blank
Assignment
IHWS13 data
2
2
2
6
83
1
Cells
tested
B7
B7
Not assignede
B7
B7
B7
B7
B7
B7
B7
B42
B7
B7
B7
B7
B7
B7
B7
B7
B7
Training B7
Training B7
B7
B7
B7
Training B7
B7
Assigned
type >0.55
NN
Normal B7
NN: B7
B7 weakly expressed,
reactive with B7 1
27 (140) sera
Short B7
Short B7, B7 sera
negative, B7 1 42
sera reactive
B7 variant, some Bw6

sera negative
Short B7, few B7 sera
reactive, similar to
B703
Short B7, negative

with B7 1 22 sera,
similar to B703
Short B7, B7 1 42
sera reactive, B7 1
22 sera negative
Comments

Expert
assigned
B7
B7
B7/B42
B7/blank
B7
B7
B7
B7
B7
Undefined
B7
B7
B7
B7
B7
B7
B7
B7
B7
B7
Not expressed
Undefined
B7
B7
B7
B7
B7
B7
B7
B7
B8
B8
B8
B8/blank
B8
HLA allele
B*0729
B*0730
B*0731
B*0732
B*0733
B*0734
B*0735
B*0736
B*0737
B*0738
B*0739
B*0740
B*0741
B*0742
B*0743
B*0744
B*0745
B*0746
B*0747
B*0748
B*0749N
B*0750
B*0751
B*0752
B*0753
B*0754
B*0755
B*0756
B*0757
B*0758
B*0801
B*0802
B*0803
B*0804
B*0805
Table 2 Continued
B8
B7
B7/B42
B7
B7
Null
B7
B7
B8
B8
WHO
assigned
B8 [5171], B59 [67]
B8 [100]a
Assigned type [%]
Cells tested
bd
1
5
B8 [100]b
B8 [80], blank [20]b
bd
6518
2
Cells
tested
B7 [100]b
B7 [100]b
B8 [99]
Assigned type [%]
NMDP
B8
B8
B0802
Assignment
IHWS13 data
61
1
Cells
tested
B8
Not assignede
B8
B7
B7
B7
B7
B7
B7
B7
B7
B7
Not assignede
B7
B7
B7
B7
B7
B7
B7
B7
B7
B7
NT
NT
B7
B7
B7
B7
B7
B7
B7
B7
Training B8
Not assignede
Assigned
type >0.55
NN
B8 Bw4; ihw13: B8
Bw4 with extra
reactions; NN: B8
B8 Bw4
Blank Bw6; ihw13:
short B8
NN: B7
Bw4 positive
B7 variant
B7x42, short B7
B blank
Comments
115
116
Expert
assigned
B8
B8
Not expressed
B8
B8
B8
B8
B8
B8
B8
B8
Undefined
B8
Not expressed
B8
B8
B8
B8
B8
B8
B8
B8
B8
B8
Not expressed
B8
B8
B8
B13
B13
B49/B15
B49/B15
HLA allele
B*0806
B*0807
B*0808N
B*0809
B*0810
B*0811
B*0812
B*0813
B*0814
B*0815
B*0816
B*0817
B*0818
B*0819N
B*0820
B*0821
B*0822
B*0823
B*0824
B*0825
B*0826
B*0827
B*0828
B*0829
B*0830N
B*0831
B*0832
B*0833
B*1301
B*1302
B*1303
B*1304
Table 2 Continued
B15/B21
B8
B8
Null
B8
B8
B8
B8
B8
Null
B8
Null
B13
B13
WHO
assigned
B21 [2238], B49 [15],

B15 [717], B15x21
[015], B50 [511],
B63 [08], B77 [47]
B13 [9599]a
B13 [98100]a
Assigned type [%]
4
9
Cells tested
B8 [100]b
B13 [97]
B13 [99]
B13 [100]b
bd
B8 [100]b
B8 [100]b
B8 [100]b
B8 [100]b
Assigned type [%]
NMDP
1
1
11
3
1
1
238
1307
1
Cells
tested
B1304
B8
B8
B13
B13
Assignment
IHWS13 data
9
17
Cells
tested
B13
B8
B8
NT
B8
B8
B8
B8
B8
B8
B8
B8
Not assignede
B8
NT
B8
B8
B8
B8
B8
B8
B8
B8
B8
B8
NT
B8
B8
B8
Training B13
Training B13
B13
Assigned
type >0.55
NN
B15x21Bw4; B21
variant with some
B15 sera reactive
B15x21Bw4, similar
to B*1303; ihw13:
new pattern, also
B49, B63 and B77
reactivity
B blank; NN: B8
Short B8
Comments

Expert
assigned
B13
Not expressed
B13
Undefined
B13
B13
B13
B13
B13
B13
B13
B13
B13
B13
B13
B64
B65
B14
B14
B14
B14
Not expressed
B62
Not expressed
B75
B72
B62
B62
B62
B62
HLA allele
B*1306
B*1307N
B*1308
B*1309
B*1310
B*1311
B*1312
B*1313
B*1314
B*1315
B*1316
B*1317
B*1318
B*1319
B*1320
B*1401
B*1402
B*1403
B*1404
B*1405
B*1406
B*1407N
B*1501
B*15010102N
B*1502
B*1503
B*1504
B*1505
B*1506
B*1507
Table 2 Continued
B62(15)
B62(15)
B62(15)
B62(15)
B72(70)
B14c
B14
Null
B62(15)
Null
B75(15)
B65(14)
Null
B13
B64(14)
WHO
assigned
B62 [90], B15 [5],

B75 [4]a
B62 [88]
B62 [93]
B14 [4958], B64

[3243], B65
[210]a
B65 [5054], B14
[4547], B64 [13]a
B62 [9398]a
B75 [7986], B15

[811], B62 [512]
B70 [4761], B72
[3145]a
17
30
16
Cells tested
Assigned type [%]
B62 [64], B15 [18]

B62 [81]b
B62 [79]
B14 [71], B65 [25],

B64 [2]
B14 [50], B65 [35]
B14 [67], B64 [33]b
B14 [40], blank [60]b
B14 [100]b
B62 [96], B15 [2]
B75 [62], B62 [22],

B15 [7]
B70 [61], B72 [10],
B35 [2], B62 [1],
blank [11]
B62 [69], B15 [10]
B13 [100]b
B13 [100]b
B14 [72], B64 [10],

B65 [10]
Assigned type [%]
NMDP
22
13
101
29
2569
40
3
5
8
1906
1035
2244
2
1
1003
Cells
tested
B62
B62
B62
25
64
18
B62
B75
B72
22
11
Cells
tested
B65
B65
B64
Assignment
IHWS13 data
B62
B62
Training B15 B62
B62
Training B70 B72
B14
B14
B14
B14
NT
Training B15 B62
NT
Training B15 B75
Training B14
B13
NT
B13
Not assignede
Not assignede
B13
B13
B13
B13
B13
B13
B13
B13
B13
B13
Training B14
Assigned
type >0.55
NN
B65
Bw6pos; NN: B13

NN: B13 B15
Comments
117
118
B76
B62
B75
B*1520
B*1521
B75/62
B*1515
B*1519
B76
B*1514
B71
B77
B*1513
B*1518
B76
B*1512
B63
B75
B*1511
B*1517
B70
B71
B*1509
B*1510
B63
B75/B62
B*1508
B*1516
Expert
assigned
HLA allele
Table 2 Continued
B75(15)
B62(15)
B76(15)
B71(70)
B63(15)
B63(15)
B62(15)
B76(15)
B77(15)
B76(15)
B75(15)
B70
B71(70)
B75(15)
WHO
assigned
B70 [5264], B71

[2834]a
B76 [29], B15 [19],
B45 [11], B62 [8],
B75 [7]
B62 [73], B15 [18],
B75 [5]
B75 [8088], B15
[69], B62 [310]
B63 [9296]
B76 [23], B45 [20],

B15 [20], B70 [6],
B63 [5]
B75 [4357], B62
[3142], B15
[815]a
B63 [9697]a
B75 [3151], B15

[2138], B46
[612], B1511
[019]
B76 [7688], B45
[36]
B77 [4653], B63
[016]
B75 [3048], B15

[1935], B62
[619], B1508
[1114]
B70 [4149], B71

[4147]a
Assigned type [%]
21
11
10
15
Cells tested
B75 [55], B62 [12],

B15 [7]
10
B62 [100]b
132
552
797
816
138
116
17
68
65
1204
45
Cells
tested
B63 [80], B57 [3],

B15 [3]
B63 [88], B15 [3],
B57 [1]
B70 [51], blank [34],
B71 [3]
B70 [50], B76 [50]b
B62 [49], B75 [28],

B15 [13]
B76 [29], B62 [18],

B75 [6], B15 [29]b
B77 [21], B63 [19],
B15 [15], B75 [12],
blank [13], B62 [8],
B53 [6]
B45 [80], B44 [20]b
B70 [53], blank [33]

B70 [49], B35 [4], B72
[2], B71 [2], B75 [1],
B15 [1], blank [13]
B62 [27], B75 [21],
B46 [15], B15 [15]
B62 [20], B15 [18],

B75 [18]
Assigned type [%]
NMDP
B75
B62
B71
B63
B63
B75
B76
B77
B76
B75
B71
B71
B75
Assignment
IHWS13 data
11
2
7
Cells
tested
Training B15 B75
B62
B76
Training B70 B71
Training B15 B63
Training B15 B63
B15
B62
Training B15 B77
Training B15 B76
B15
Training B70 B71

Training B70 B71
B15
Assigned
type >0.55
NN
ihw13: short B62
ihw13: short B75
Comments

Expert
assigned
B70/B5/blank
B62
B62
Not expressed
B62
B62
B70
B62
B75
B62
B62
B62
B62
Undefined
B70
B62
B62
B62/blank
B15
HLA allele
B*1523
B*1524
B*1525
B*1526N
B*1527
B*1528
B*1529
B*1530
B*1531
B*1532
B*1533
B*1534
B*1535
B*1536
B*1537
B*1538
B*1539
B*1540
B*1542
Table 2 Continued
B70 [46], B71 [11],

B78 [9]
B62 [9298]
B70c
B62(15)c
B75(15)
B62(15)
B15
B62(15)c
B62(15)c
B62(15)c
B70 [5458], B15

[1112], B71 [710]
B62 [6386], B75
[413], B15 [1219]
B62 [8693], B75

[57]a
B62(15)c
B15
Null
B62(15)
B62(15)
B62 [4548], B1524

[2324], B15
[2122], B77 [46],
B63 [23]
B62 [8694], B75
[210]a
B62 [97]a
B1523 [17], B5
[1415], B77
[711], B70 [79],
B15 [58]
Assigned type [%]
B62(15)
WHO
assigned
14
10
Cells tested
B62 [84], B15 [13]b

Blank [61], B70 [10],
B62 [8]
38
26
B62 [100]b
B13 [100]b
24
13
5
8
34
B75 [38], B62 [38]b

B62 [100]b
B62 [100]b
B62 [79]
Blank [54], B70 [30]
98
5
21
76
116
54
12
Cells
tested
B62 [64], B15 [17]
B62 [80], B15 [20]b

Blank [71], B70 [19]
B62 [74], B75 [8],

B15 [7]
B62 [76], B15 [7]
B62 [44], blank [22]
Blank [50], B70 [17],

B51 [17], B53 [8]b
Assigned type [%]
NMDP
B62
B75
B62
B62
B71
B62
B62
B62
B1523
Assignment
IHWS13 data
Cells
tested
e
B62
B62
B62
B62
B71
B15
B75
B62
B62
B62
Training B15 B62
Training B15 B62
B62
B71
NT
Training B15 B62
Training B15 B62
B15
Not assigned
Assigned
type >0.55
NN
Short B15; reactive

with some B22 sera
Short B62
B62 variant, also

reactive with B52
sera
Bw4 positive, NN:

B77
B62
Normal B62
ihw13: short B62,

short B75
ihw13: short B75
ihw13: short B62,

short B75
ihw13: short B62,

short B75
B5x70Bw4, B5/53/
77 variant; NM5;
ihw13: new
pattern, short B71Bw4; NN: B70 B71
B62 Bw4
Comments
119
120
Expert
assigned
B15
B75
B62
Undefined
B70/blank
B62
B72
B62
B70
Undefined
Undefined
B72
B15
B62
B62
B62
B62
B72
Undefined
B62
B71
B62
B62
B63
Undefined
B72
B62
B62
B71
B62
B72
B62
Undefined
B62
B62
HLA allele
B*1543
B*1544
B*1545
B*1546
B*1547
B*1548
B*1549
B*1550
B*1551
B*1552
B*1553
B*1554
B*1555
B*1556
B*1557
B*1558
B*1560
B*1561
B*1562
B*1563
B*1564
B*1565
B*1566
B*1567
B*1568
B*1569
B*1570
B*1571
B*1572
B*1573
B*1574
B*1575
B*1576
B*1577
B*1578
Table 2 Continued
B62(15)
B62(15)
B15
B62(15)
B70
B15
B15
B62(15)
B35
B62(15)
B62(15)
B72(70)
WHO
assigned
Assigned type [%]
Cells tested
13
4
14
3
1
3
3
2
2
1
B62 [100]b
B35 [100]b
Blank [67]b
B70 [50], B72 [50]b
B62 [100]b
B62 [67]b
B62 [100]b
B62 [100]b
B62 [100]b
B62 [83], B75 [17]b
B62 [100]b
B62 [100]b
Cells
tested
B62 [92]b
B50 [50], B72 [25]b
Blank [57], B35 [14]b
Assigned type [%]
NMDP
B62
Assignment
IHWS13 data
Cells
tested
B62
B71
B62
B72
B62
Not assignede
B62
B62
B62
B72
B62
B71
B71
Not assignede
B72
B15f
B62
B62
B62
B62
B72
Not assignede
B62
B71
B62
B62
B63
Not assignede
B72
B62
B75
B62
Not assignede
B72
B15f
Assigned
type >0.55
NN
NN: B15
ihw13: short B62,

short B75
Bw4 positive
NN: B70 B72
NN: B70 B72
B15 or B62
B15 Bw6; NN: B75
B15
NN: B15 B62

B48, all B15 sera
negative
Bw4 positive, NN:

B62
Comments

Expert
assigned
Not expressed
B70
B62
B62
B62
B62
B62
Undefined
B15
B75
B77
B71
Undefined
B62
B71
Not expressed
B63
B62
B62
B72
B71
Undefined
B62
B70
B62
B62
Undefined
B62
B71
B62
B62
Not expressed
B75
B62
B70
B70
B62
B62
HLA allele
B*1579N
B*1580
B*1581
B*1582
B*1583
B*1584
B*1585
B*1586
B*1587
B*1588
B*1589
B*1590
B*1591
B*1592
B*1593
B*1594N
B*1595
B*1596
B*1597
B*1598
B*1599
B*9501
B*9502
B*9503
B*9504
B*9505
B*9506
B*9507
B*9508
B*9509
B*9510
B*9511N
B*9512
B*9513
B*9514
B*9515
B*9516
B*9517
Table 2 Continued
Null
B70
B62(15)
B62(15)
B71(70)
Null
B62(15)
B62(15)
B70
B62(15)
B71(70)
Null
B15
B70
WHO
assigned
Assigned type [%]
Cells tested
Assigned type [%]
NMDP
Cells
tested
Assignment
IHWS13 data
Cells
tested
NT
B71
B62
B62
B62
B62
B62
Not assignede
B15
B75
B77
B71
Not assignede
B62
B71
NT
B63
B62
B62
B72
B71
Not assignede
B62
B72
B62
B62
Not assignede
B62
B71
B62
B62
NT
B75
B62
B71
B70
B62
B62
Assigned
type >0.55
NN
NN: B15, B62
NN: B15, B46
NN: B70, B72, B12
NN: B15, B62
B62 1 A30/31
NN: B15
B70
Comments
121
122
B18
B18
B18
B18
B18
B18
Not expressed
B18
B18
B18/blank
B*1807
B*1810
B*1811
B*1812
B*1813
B*1814
B*1815
B*1817N
B*1818
B*1819
B18
B*1806
B18
B18
B62
B71
B62
B75
B62
B72
B71
B62
B62
B72
B62
B62
B62
B72
B18
B18
B18
B18
B18
B*9518
B*9519
B*9520
B*9521
B*9522
B*9523
B*9524
B*9525
B*9526
B*9527
B*9528
B*9529
B*9530
B*9532
B*1801
B*1802
B*1803
B*1804
B*1805
B*1808
B*1809
Expert
assigned
HLA allele
Table 2 Continued
Null
B18
B18
B18
B18
B18
B18c
B18
WHO
assigned
B18 [97100]a
Assigned type [%]
12
Cells tested
B18 [50], blank [50]b

B18 [100]b
B18 [100]b
B18 [100]b
B18 [100]b
2
2
2
1
Blank [100]b
B18 [100]b
1641
31
29
19
6
Cells
tested
B18 [96]
B18 [90]
B18 [83], blank [17]
B18 [84], blank [11]b
B18 [83]b
Assigned type [%]
NMDP
B18
B18
B18
B18
B18
B18
Assignment
IHWS13 data
53
3
1
1
1
Cells
tested
B18
B18
B18
B18
B18
B18
NT
B18
B18
B18
Not assignede
B18
B18
B62
B71
B62
B75
B62
B72
B71
B62
B62
B72
B62
B62
B62
B72
Training B18
Training B18
B18
Not assignede
B18
Assigned
type >0.55
NN
B18, Bw4; NN: B18,

B38
NN: B18
ihw13: short B18,
blank
B18 variant, negative
with Bw4 and Bw6
sera
ihw13: short B18,
blank, B18 spec
sera negative
Comments

Expert
assigned
B18
Undefined
B18
Not expressed
B18
B18
B18
B27
B27
B27
B27
B27
B27
B27
B2708/B27/B7
B27
B27
B27
Undefined
B27
B27
B27
B27
B27
Undefined
B27
B27
HLA allele
B*1820
B*1821
B*1822
B*1823N
B*1824
B*1825
B*1826
B*2701
B*2702
B*2703
B*2704
B*2705
B*2706
B*2707
B*2708
B*2709
B*2710
B*2711
B*2712
B*2713
B*2714
B*2715
B*2716
B*2717
B*2718
B*2719
B*2720
Table 2 Continued
B27
B27
B27
B27
B27c
B27
B27
B27
B27
B27
B2708
Null
B27
B27
B27
B27
B27
B27
WHO
assigned
B27 [100]
B2708 [3658],
B7 [1941], B27
[1119]
B27 [97]
B27 [97]
B27 [98]a
B27 [99100]
B27 [9799]a
Assigned type [%]
1
1
1
6
10
Cells tested
15
5
2
B27 [100]b
B27 [100]b
B27 [100]b
Blank [100]b
B27 [100]b
14
23
49
32
B27 [100]b
B27 [31], B7 [34],
blank [16], B2708
[9]b
Blank [78], B60 [9],

B27 [4], B61 [4]b
12
417
26
31
1194
29
Cells
tested
B27 [100]b
B27 [87]
B27 [88]
B27 [97]
B27 [99]
B27 [97]
Assigned type [%]
NMDP
Blank
B27
B2708
B27
B27
B27
B27
B27
Assignment
IHWS13 data
5
1
9
5
7
22
6
Cells
tested
B27
Not assignede
B27
B27
B27
B27
B27
B27
Not assignede
B27
B27
Not assignede
B27
B27
B18
Not assignede
B18
NT
B18
B18
B18
B27
Training B27
Training B27
B27
Training B27
B27
Assigned
type >0.55
NN
Blank Bw4
Short B27, some B40
sera reactive
Normal B27
Bw6 positive
Normal B27
B27 variant, extra

reactivity with B40
sera; NN: B27
Blank Bw6; B27 sera
negative, B7 1 27
(140) sera positive;
ihw13: blank, B61
B27Bw6; NN: B27
B7 variant, most B27

sera negative;
ihw13: also B73 B7
blank
Previously also
named B*2722
ihw13: short B27
NN: B18
Comments
123
124
Expert
assigned
B27
Undefined
B27
B27
B27
B27
B27
B27
B27
B27
B27
Undefined
B27
B27
B27
B27
B27
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
HLA allele
B*2721
B*2723
B*2724
B*2725
B*2726
B*2727
B*2728
B*2729
B*2730
B*2731
B*2732
B*2733
B*2734
B*2735
B*2736
B*2737
B*2738
B*3501
B*3502
B*3503
B*3504
B*3505
B*3506
B*3507
B*3508
B*3509
B*3510
B*3511
B*3512
B*3513
B*3514
B*3515
B*3516
B*3517
Table 2 Continued
B35 [97100]a
B35 [9499]
B35 [95100]
B35 [9899]
B35 [9598]a
B35 [98100]a
B35 [98]a
B35 [63], B70 [20]

B35 [97100]
B35c
B35
Assigned type [%]
B27
B27
B27
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35c
B35
B35
B35
B35
B35
WHO
assigned
2
9
27
3
3
12
Cells tested
B35 [33], blank [34]

B35 [93]
B35 [98]
B35 [72]
B35 [94]
B35 [100]
B35 [94]
B35 [100]b
B35 [91]
B35 [100]b
B35 [77], B70 [15]b
B35 [88]b
B35 [78]
B35 [79]
Blank [50], B35 [33]b
Assigned type [%]
NMDP
41
261
29
6
2023
1013
1226
26
231
13
345
3
13
16
422
Cells
tested
B35
B35
B35
B35
B35
B35
B35
B35
B35
Assignment
IHWS13 data
1
2
58
9
22
Cells
tested
B35
Training B35
B27
B27
B27
B27
B27
Not assignede
B27
B27
B27
Not assignede
B27
B27
B27
B27
B27
Training B35
Training B35
Training B35
B35
Training B35
B35
B35
Training B35
B35
B35
B35
B35
B35
B35
B35
B27
Not assignede
Assigned
type >0.55
NN
Short B35, B75 CREG

sera reactive
ihw13: short B35
ihw13: short B35
NN: B27, B40, B61

NN: B27
NN: B27
Blank Bw6, Bw4

negative/weak,
only reactive with
few B44 1 27 sera
Comments

Expert
assigned
B35
B35/blank
B35
B35/B78
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
Not expressed
B35
B35
B35
Undefined
B35
B35
B35
B35
HLA allele
B*3518
B*3519
B*3520
B*3521
B*3522
B*3523
B*3524
B*3525
B*3526
B*3527
B*3528
B*3529
B*3530
B*3531
B*3532
B*3533
B*3534
B*3535
B*3536
B*3537
B*3538
B*3539
B*3540N
B*3541
B*3542
B*3543
B*3544
B*3545
B*3546
B*3547
B*3548
Table 2 Continued
B35
B35
B35
B35
Null
B35
B35
B35
B35c
B35c
B35
B35
B35
B35
B35
B35
WHO
assigned
B35 [9597]a
B35 [8488]
Assigned type [%]
Cells tested
B35 [100]b
B35 [100]b
B35 [63], B70 [12]
bd
B35 [100]b
B35 [100]b
B35 [100]b
B35 [100]b
B35 [42], blank [13]

B35 [42], B78 [33],
blank [25]b
B35 [100]b
B35 [92]b
B35 [75], B78 [25]b
B35 [33], blank [67]b
B35 [100]b
B35 [50], blank [43]b
B35 [100]b
B35 [100]b
Blank [67], B61 [17],
B48 [17]b
B35 [100]
B35 [40], B70 [20],
B77 [20]b
Assigned type [%]
NMDP
1
1
1
379
2
13
8
3
2
14
2
7
6
23
12
1
5
Cells
tested
B35
B35
B35
B35
B35
B78
Blank
Assignment
IHWS13 data
5
1
Cells
tested
Not assignede
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
NT
B35
B35
Not assignede
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
B35
Assigned
type >0.55
NN
Normal B35
Previously B*1522;
NN: B35
Previously B*1559
Normal B35
ihw13: short B35;
reactive with few
B40 and B35 sera,
Korean
ihw13: short B35
ihw13: B35/78 variant
ihw13: new pattern,

blank, very short
B35
Comments
125
126
Expert
assigned
B35
B35
B35
B35
Not expressed
B35
B35
B35
B35
B35
B35
B35
B35
B35
Undefined
B35
B35
B35
Undefined
B35
B35
B35
B35
B35
B35
B35
B35
B35/22
B35
B37
B37/B27
Not expressed
HLA allele
B*3549
B*3550
B*3551
B*3552
B*3553N
B*3554
B*3555
B*3556
B*3557
B*3558
B*3559
B*3560
B*3561
B*3562
B*3563
B*3564
B*3565Q
B*3566
B*3567
B*3568
B*3569
B*3570
B*3571
B*3572
B*3573
B*3574
B*3575
B*3576
B*3577
B*3701
B*3702
B*3703N
Table 2 Continued
Null
B35
B35/22
B37
B35
B35
B35
Null
B35
B35
B35
B35
WHO
assigned
B37 [98100]a
Assigned type [%]
Cells tested
1721
6
Blank [100]b
B37 [93]
B27 [33], blank [33],
B37 [17], B47 [17]b
B35 [100]b
Cells
tested
Assigned type [%]
NMDP
B37
Assignment
IHWS13 data
27
Cells
tested
NT
B35
Not assignede
B35
B35
B35
B35
B35
B35
B35
B35
B22f
B35
Training B37
Not assignede
B35
B35
B35
B35
NT
B35
B35
B35
B35
B35
B35
Not assignede
B35
B35
Not assignede
B35
B35
Assigned
type >0.55
NN
B37x27 or blank; few

B37 and few B27
sera reactive; NN:
B37
NN: B56
NN: B35
Not expected to be
expressed
NN: B40
NN: B35
Comments

Expert
assigned
B37
Blank
B37
Undefined
B37
B37
B37
Undefined
B37
B37
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B38
B3901/B39
Low B39
HLA allele
B*3704
B*3705
B*3706
B*3707
B*3708
B*3709
B*3710
B*3711
B*3712
B*3713
B*3801
B*3802
B*3803
B*3804
B*3805
B*3806
B*3807
B*3808
B*3809
B*3810
B*3811
B*3812
B*3813
B*3814
B*3815
B*3816
B*3901
B*39010102L
Table 2 Continued
B38(16)
B38(16)
B3901
Low B39
B38(16)
B16c
B16
B38(16)
B37
B37
B37
B38(16)
B37
WHO
assigned
B39 [9699]a
15
B38 [9199]a
14
Cells tested
B38 [96100]a
Assigned type [%]
B39 [95]
B38 [94], B16 [1],

B39 [1]
B38 [87], B39 [2],
B16 [2]
Blank [100]b
B37 [50], blank [50]
Assigned type [%]
NMDP
476
788
2317
Cells
tested
B39
B38
B38
B37
Assignment
IHWS13 data
21
15
43
Cells
tested
B38
B38
B38
B38
B38
B38
B38
Training B16 B39
Identical to B*3901
B38
B38
B38
B38
B38
B38
Not assignede
Training B16 B38
B37
Not assignede
B37
Not assignede
B37
Not assignede
B37
B37
Training B16 B38
Not assignede
B37
Assigned
type >0.55
NN
B16Bw4, on cell
VOA Ter 299
Normal B38
ihw13: different from

B*3801
B16 Bw4, B38, and
B39 sera negative;
NN: B16 B38
NN: B37
NN: B37
B37 variant, reactive

with few B37 and
B18 sera
Blank Bw6, B37, and
Bw4 sera negative,
Korean; NN: B37
Comments
127
128
Expert
assigned
B3902/B39
B39
B39
B39
B39
B16
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
Not expressed
B39
B39
B39
B39
B39
B39
B16
B39
B39
B39
HLA allele
B*3902
B*3903
B*3904
B*3905
B*3906
B*3907
B*3908
B*3909
B*3910
B*3911
B*3912
B*3913
B*3914
B*3915
B*3916
B*3917
B*3918
B*3919
B*3920
B*3922
B*3923
B*3924
B*3925N
B*3926
B*3927
B*3928
B*3929
B*3930
B*3931
B*3932
B*3933
B*3934
B*3935
Table 2 Continued
B39(16)
B39(16)
B39(16)c
B39(16)
B39(16)
B39(16)c
B39(16)c
B39(16)
B39(16)
Null
B39(16)
B39(16)
B39(16)
B39(16)
B39(16)
B39(16)
B39c
B3902
WHO
assigned
B39 [9699]
B39 [98]a
B39 [73], B16 [16]a
B39 [9699]
B39 [8691], B16

[35]
6
4
17
B39 [9799]a
B39 [8992], B16

[47], B38 [15]a
Cells tested
Assigned type [%]
29
127
29
1
5
4
6
1
3
1
30
B39 [100]b
B39 [82], blank [16]
B39 [79], blank [14]b
B39 [100]b
B39 [40], blank [40]b
B39 [100]b
B39 [100]b
B39 [100]b
Blank [100]b
Blank [67], B38 [33]b
B39 [97]b
B39 [100]b
B39 [100]b
bd
508
1
57
245
19
96
Cells
tested
B39 [94]
Blank [100]b
B39 [48], blank [41]
B39 [89]
B39 [82]
B39 [87]
Assigned type [%]
NMDP
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
B39
Assignment
IHWS13 data
2
5
Cells
tested
B39
B39
B39
B39
Not assignede
B39
B39
B39
Not assignede
B39
B39
B16f
B39
Not assignede
B39
NT
B39
B39
B39
B39
B39
B39
B16f
B39
B39
B39
Training B16 B39

B16
Not assignede
B39
B39
B39
Not assignede
Assigned
type >0.55
NN
NN: B39
Normal B39
NN: B16, B39

Normal B39
NN: B38
NN: B39, B16
NN: B16, B39
ihw13: B39 and B38

sera positive; NN:
B16
B39 variant, ST-16;

ihw13: B39 and
B38 sera positive
ihw13: short B39; NN:

B16 B39
Comments

Expert
assigned
Undefined
B39
B39
B39
Not expressed
B39
B39
B60
B61
B61
B61
B4005/B50
B61
B60
B61/blank
B61
B60
B61
B60/B48
Undefined
B60
HLA allele
B*3936
B*3937
B*3938Q
B*3939
B*3940N
B*3941
B*3942
B*4001
B*4002
B*4003
B*4004
B*4005
B*4006
B*4007
B*4008
B*4009
B*4010
B*4011
B*4012
B*4013
B*4014
Table 2 Continued
B60(40)
B61(40)c
B61(40)
B60(40)
B60(40)c
B61(40)
B61(40)c
B61(40)c
B4005
B61(40)
Null
B39(16)
B60(40)
WHO
assigned
B60 [7593], B40

[1415], B61 [38],
B48 [23]a
B48 [2834], B70 [7

20], B40 [11], B72
[10], B4012 [8],
B61 [5]
B61 [8790], B40 [4],

B60 [48]a
B61 [2027], B40

[2030], B4008
[910], B48 [214]
B61 [7595], B40

[319], B60 [221]a
B4005 [4157], B50

[2836], B21 [59]
B60 [9698]a
Assigned type [%]
10
24
37
Cells tested
1
3
B60 [100]b
38
19
5
28
12
138
585
31
57
293
1460
3854
Cells
tested
Blank [100]b
B61 [60], B40 [20]b

B60 [43], B61 [25],
B40 [14], blank
[11]b
B61 [71], B60 [26]b
B48 [37], B60 [26],
blank [21], B40
[16]b
B60 [93], B40 [4],

B61 [2]
B61 [80], B60 [8],
B40 [6]
B61 [62], B60 [23]
B61 [47], B60 [12]
B50 [34], B4005 [12],
blank [23], B61 [7],
B70 [4], B21 [4],
B60 [4]
B61 [75], B60 [5],
B40 [5]
B60 [100]b
Blank [71], B61 [12],
B40 [9]
Assigned type [%]
NMDP
B61
B61
B60
B61
B61
B61
B61
B61
B60
Assignment
IHWS13 data
1
2
17
1
3
33
48
Cells
tested
e
B40f
Not assignede
B61
Not assignede
B61
B60
B60
B61
Training B40 B61
B61
B61
B61
Training B40 B61
B39
NT
B39
B39
Training B40 B60
Not assigned
B39
B39
Assigned
type >0.55
NN
B48x70, some
reactivity with B40
1 48 and B15 1 70
CREG sera; NN:
B48
B40 Bw4; NN: B61
B40
NN: B60
Short B60, B48 like
BFu
B40x48 variant, only
reactive with some
B40 1 48 (17)
CREG sera
BN21, B21 variant
Not expected to be
expressed
NN: B39, B16, B14
Comments
129
130
Expert
assigned
Undefined
B61
B61
B61
B61
B40/B15
Not expressed
B40
B61
B40
B21
B61
Undefined
B61
B60
B60
B40
B60
B60
B61
B60
B61
B60
B61/B41
HLA allele
B*4015
B*4016
B*4018
B*4019
B*4020
B*4021
B*4022N
B*4023
B*4024
B*4025
B*4026
B*4027
B*4028
B*4029
B*4030
B*4031
B*4032
B*4033
B*4034
B*4035
B*4036
B*4037
B*4038
B*4039
Table 2 Continued
B41
B60(40)
B60(40)
B61(40)
B21
B61(40)
B61(40)
Null
B61(40)c
Assigned type [%]
B61(40)
WHO
assigned
Cells tested
B61 [100]b
B60 [50], B61 [50]b
bd
B61 [68], B60 [26]b
B61 [77], B60 [8],

B40 [8]b
B61 [58], B60 [25],

B40 [17]b
B61 [100]b
Assigned type [%]
NMDP
1
2
19
13
12
Cells
tested
B61
B60
B61
B4019
Assignment
IHWS13 data
1
1
Cells
tested
B60
B61
B60
B61
B60
Not assignede
B60
B60
B61
B40f
B61
Not assignede
B61
B60
NT
B40f
B61
B60
Not assignede
B61
Short B40, B60 sera

negative
ihw13: B61 with few

B60 sera pos
Normal B60
NN: B40, B41
Short B40, few B40

sera reactive
NN: B61
Normal B61
NN: B40, B61
NN: B60
B40x15, reactive with

B40 1 48, B15 1 57
sera, not with B40
1 13 sera; NN: B15,
B48
B40Bw4, B*4002
with Bw4 epitope;
ihw13: new pattern
short B61 Bw4
positive; NN: B61,
B40
NN: B41
NN: B40, B41
Not assignede
Not assignede
B61
Not assignede
Comments
Assigned
type >0.55
NN

Expert
assigned
B61
B60
B60
B61
B60
B60
B40
B60
B60
B61
Undefined
B60
B61
B60
B60
B61
B61
B40
B40
Undefined
B60
B60
B60
B61
B60
B60
B60
Undefined
B60
B61
B61
B60
B60
B60
B61
B60
HLA allele
B*4040
B*4042
B*4043
B*4044
B*4045
B*4046
B*4047
B*4048
B*4049
B*4050
B*4051
B*4052
B*4053
B*4054
B*4055
B*4056
B*4057
B*4058
B*4059
B*4060
B*4061
B*4062
B*4063
B*4064
B*4065
B*4066
B*4067
B*4068
B*4069
B*4070
B*4071
B*4072
B*4073
B*4074
B*4075
B*4076
Table 2 Continued
B60(40)
B61(40)
B60(40)
B61(40)
B60(40)
B61(40)
B40
B61(40)
B40
WHO
assigned
Assigned type [%]
Cells tested
B61 [100]
Assigned type [%]
NMDP
Cells
tested
Assignment
IHWS13 data
Cells
tested
B60
B60
B61
Not assignede
B60
B61
B60
B60
B61
B61
B40
B40f
Not assignede
B60
B60
B60
B61
B60
B60
B60
Not assignede
B60
B61
B61
B60
B60
B60
B61
B60
B61
B60
B60
B61
B60
B60
Not assignede
Assigned
type >0.55
NN
NN: B40, B61
NN: B60
NN: B60, B40
NN: B40
B40 Bw4; short B60,

Bw4pos: NN: B40,
B60
Comments
131
132
Expert
assigned
B60
B41
B41
B41
B41
B41
B41
B41
B41
B42
B42
B42
B42
B42
Undefined
B42
B42
B44
See comment
B44
B44
B44
B44
B44
B44
HLA allele
B*4077
B*4101
B*4102
B*4103
B*4104
B*4105
B*4106
B*4107
B*4108
B*4201
B*4202
B*4204
B*4205
B*4206
B*4207
B*4208
B*4209
B*4402
B*44020102S
B*4403
B*4404
B*4405
B*4406
B*4407
B*4408
Table 2 Continued
B44(12)
B44(12)
B44(12)
B44(12)
B44(12)
B44(12)
B44(12)
Soluble
B42
B42
B41
B41
B41
WHO
assigned
30
B44 [97100]a
12
7
9
Cells tested
B42 [8796], B67

[012]
B44 [99100]
B42 [8997]a
B41 [9195]a
B41 [9195]
Assigned type [%]
2854
42
130
13
3
3
B44 [100]b
B44 [100]b
6959
80
1015
543
478
13
Cells
tested
B44 [94]
B44 [65]
B44 [92]
B44 [46], blank [31]b
Blank [100]b
B44 [98]
B42 [93], B55 [1], B7

[1]
B42 [95]
B41 [87]
B41 [87]
B41 [92]b
Assigned type [%]
NMDP
B44
B44
B44
B44
B44
B44
B42
B42
B41
B41
Assignment
IHWS13 data
65
7
1
7
55
14
16
Cells
tested
B44
B44
Training B12 B44

B44
B44
Not assignede
B42
B42
B42
Not assignede
B42
B42
Training B12 B44
Identical to B*4402
Training B42
B41
B41
B41
Training B42
B60
Training B41
Training B41
B41
B41
B41
Assigned
type >0.55
NN
Short B44; also

reactive with B62 1
63 1 57 sera, in
Welsh, but very
rare; ihw13: new
pattern
Short B44 or blank;

ihw13: blank, short
B44; NN: B44, B12
ihw13: short B44
Secreted molecule
only (reference: 62)
NN: B42, B8
Short B41, Bw6 sera

negative
Comments

Expert
assigned
B45
B44
B44
B44
B44
B44
B12
B47/B44
B44
B44
Not expressed
B44
B44
B44
Not expressed
B44
B44
B44
B44
B44
B44
B44
B44
B44
B44
B44
B44
B44
B44
HLA allele
B*4409
B*4410
B*4411
B*4412
B*4413
B*4414
B*4415
B*4416
B*4417
B*4418
B*4419N
B*4420
B*4421
B*4422
B*4423N
B*4424
B*4425
B*4426
B*4427
B*4428
B*4429
B*4430
B*4431
B*4432
B*4433
B*4434
B*4435
B*4436
B*4437
Table 2 Continued
B44(12)
Null
B44(12)
B44(12)c
B44(12)
B44(12)
Null
B47
B44(12)c
B44(12)
B44(12)
B44(12)
B12
B45(12)
WHO
assigned
B47 [52], B44 [12]
Assigned type [%]
Cells tested
30
B44 [100]b
B44 [100]b
B44 [100]b
B44 [100]b
bd
1
1
1
1
B44 [100]b
B44 [100]b
B44 [100]b
B44 [100]b
37
2
12
Cells
tested
B44 [70]
B44 [100]b
B45 [92]
Assigned type [%]
NMDP
Blank
B44
B45
Assignment
IHWS13 data
Cells
tested
B44
B44
B44
B44
B44
B44
B44
NT
B44
B44
B44
B44
B44
B44
B44
Not assignede
B44
B12f
NT
B44
B44
B44
B12f
B44
B44
B44
B44
B45
B12
Assigned
type >0.55
NN
Normal B44
Almost normal B44;

NN: B60, B40, B12
Short B44
Normal B44
Short B44
ihw13: blank or very

short B44
NN: B49
Short B44
B45 Bw4, will be
typed as B44 or B12
most B47 and few
B44/12 sera
B44Bw6, will be
typed as B45 or
B12; most B44- and
B45-specific sera
negative
NN: B44
Comments
133
134
Expert
assigned
B44
B44
B44
B44
Undefined
B44
B44
B44
B12
B44
B44
B44
B44
B44
Not expressed
B44
B44
B45
B45
B45
B21
B45
B45
B45
B46
B46
B46
B46
B46
Undefined
Not expressed
B46
B46
B46
B22
HLA allele
B*4438
B*4439
B*4440
B*4441
B*4442
B*4443
B*4444
B*4445
B*4446
B*4447
B*4448
B*4449
B*4450
B*4451
B*4452N
B*4453
B*4454
B*4501
B*4502
B*4503
B*4504
B*4505
B*4506
B*4507
B*4601
B*4602
B*4603
B*4604
B*4605
B*4606
B*4607N
B*4608
B*4609
B*4610
B*4611
Table 2 Continued
B46
B46
B46
Null
B46
B46
B44(12)
B21
B44(12)
Null
B44(12)
B44(12)
B45(12)
WHO
assigned
B46 [9197]a
B45 [9699]
Assigned type [%]
17
Cells tested
B45 [93], B12 [1],

B44 [1], B50 [1]
B45 [100]b
B45 [100]b
B46 [58], blank [27],

B62 [1], B35 [1]
Assigned type [%]
NMDP
1487
2307
Cells
tested
B46
B45
Assignment
IHWS13 data
30
16
Cells
tested
B46
B46
B46
Not assignede
NT
B46
B46
B46
B22
B46
B45
B45
B21f
B45
B12f
B45
Training B46
B44
B44
B44
B44
B44
B44
B44
B44
B12
B44
B44
B44
B44
B44
NT
B44
B44
Training B12 B45
Assigned
type >0.55
NN
NN: B46, B81
B46 variant, negative

with B46 1 75 sera
NN: B45
NN: B50
Comments

Expert
assigned
B47
B47
B47
Undefined
B17
B48
B48/B70
B48
B48
B48
Undefined
B48
Undefined
B48
B48
B48
B48
Undefined
B48
B48
B48
Undefined
B48
B49
B49
B49
HLA allele
B*4701
B*4702
B*4703
B*4704
B*4705
B*4801
B*4802
B*4803
B*4804
B*4805
B*4806
B*4807
B*4808
B*4809
B*4810
B*4811
B*4812
B*4813
B*4814
B*4815
B*4816
B*4817
B*4818
B*4901
B*4902
B*4903
Table 2 Continued
B49(21)
B49 [9498]a
B48 [97]a
B48c
B48
B48
B48
B48
B48
B48/40
B49(21)
B47 [7077], B60

[49], B61 [78],
B40 [67]
B48 [90100]a
B47 [9096]
Assigned type [%]
B48
B48
B47
B47
B47
WHO
assigned
26
Cells tested
B48 [66], B60 [13]

B48 [50], B40 [25]b
B60 [42], B48 [33],

B61 [8]b
B49 [94], B50 [1],

B21 [1]
B49 [100]b
Blank [33], B47 [17],

B13 [17], B40 [17],
B61 [17]b
B48 [78], B60 [6],

B61 [2], B40 [2]
Blank [44], B35 [16],
B70 [13], B48 [3]
B47 [50], B27 [5],

blank [32]
B47 [40], blank [40],
B60 [20]b
Assigned type [%]
NMDP
3002
32
4
12
39
610
B49
B49
B48
B48
B71
B48
B47
B61
B47
311
5
Assignment
Cells
tested
IHWS13 data
22
11
12
Cells
tested
B49
Not assignede
Not assignede
B48
B48
B48
B48
Not assignede
B48
B48
B48
Not assignede
B48
Training B21 B49
B48
B48
Not assignede
Not assignede
B48
Not assignede
Not assignede
B47
Training B48
B47
Not assignede
Training B47
Assigned
type >0.55
NN
Normal B49
Short B49; NN:
B49, B21
NN: B48
NN: B48, B61
NN: B7, B48
Normal B48
NN: B48, B7
NN: B48
B71 like; ihw13:

pattern identical to
B*1510; NN: B35
B47 Bw6, B47 1 13 1

27 sera negative,
B40 1 13 1 47 sera
positive; NN: B47
B47 Bw4, B47 1 13
sera negative, B40
1 13 sera positive
NN: B47
Comments
135
136
B51
B51
B51
B*5105
B*5106
B*5107
B51
B51
Undefined
B51
B51
B5103/B51
B51
B*5103
B*5104
B*5113
B*5114
B*5115
B*5116
B*5117
B5102/B51
B*5102
Not expressed
B51/blank
B50
B51
B*5004
B*5101
B*5111N
B*5112
B45
B*5002
B51
B51
B51
B49
B49
B50
B*4904
B*4905
B*5001
B*5108
B*5109
B*5110
Expert
assigned
HLA allele
Table 2 Continued
B51(5)c
B5
B51(5)
Null
B51(5)
B51(5)
B51(5)
B51(5)
B51(5)
B5103
B51(5)c
B5102
B50(21)
B51(5)
B45(12)
B49(21)
B50(21)
WHO
assigned
B51 [9598]a
11
40
12
Cells tested
B51 [9699]a
B51 [8288], B53

[14], B52 [04],
B5102 [03]a
B51 [45], B53 [33],

B5 [3], B52 [3]
B51 [3857], B5102

[2133], B53
[816], B5 [47],
B52 [37]
B45 [8791], B50 [7],

B44 [5]a
B51 [9699]
B50 [9297]a
Assigned type [%]
B51 [100]b
B51 [88], B5 [12]b
B51 [100]b
B51 [77], B53 [4]

B51 [86]
Blank [100]b
B51 [78], B52 [9]
B51 [64], B53 [12],

B52 [7]
B51 [100]b
B51 [75], B52 [12],
B5 [12]b
B51 [48], B53 [24],
B52 [16]
B50 [67]b
B51 [96], B5 [2],
B52 [1]
B51 [73], B53 [11],
B52 [6], B5102 [3],
B5 [3]
B50 [85], B21 [3],

B49 [2], B45 [1]
B45 [96]
Assigned type [%]
NMDP
7
17
154
43
2
68
42
25
3
8
218
3
1899
79
1700
Cells
tested
B51
B51
B51
B51
B51
B51
B51
B5102
B51
B45
B50
Assignment
IHWS13 data
88
20
Cells
tested
B51
B51
Not assignede
B51
B51
NT
B51
Training B5 B51
Training B5 B51
B51
Training B5 B51
B51
B51
B51
B51
B51
B50
Training B5 B51
Training B12 B45
B49
B49
Training B21 B50
Assigned
type >0.55
NN
NN: B59
B blank, possibly not

expressed
ihw13: B5102, short

B51 with some B35
1 53 sera reactive
ihw13: B5102, short

B51 with some B35
1 53 sera reactive
B5, most B51 sera
negative; ihw13:
short B51, distinct
pattern
ihw13: short B51,
distinct pattern
ihw13: short B51 with

some B35 1 53
sera reactive
Comments

Expert
assigned
B51
B51
B51
B51
B51
B51
B51
B51
Not expressed
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
Not expressed
Undefined
B51
Not expressed
Undefined
B51
B51
B51
B51
B52
B52
B52
B52
B52
B52
HLA allele
B*5118
B*5119
B*5120
B*5121
B*5122
B*5123
B*5124
B*5126
B*5127N
B*5128
B*5129
B*5130
B*5131
B*5132
B*5133
B*5134
B*5135
B*5136
B*5137
B*5138
B*5139
B*5140
B*5141N
B*5142
B*5143
B*5144N
B*5145
B*5146
B*5147
B*5148
B*5149
B*5201
B*5202
B*5203
B*5204
B*5205
B*5206
Table 2 Continued
B52(5)
B51(5)
B51(5)
Null
B51(5)
B51(5)
B51(5)
B51(5)
Null
B44(12)
B51(5)
Null
B51(5)
B52(5)
WHO
assigned
B52 [76], B5 [11]
B52 [9395]
Assigned type [%]
13
Cells tested
B52 [82], B51 [7],

B5 [2], B53 [1]
B52 [100]b
B52 [100]b
B51 [100]b
B51 [100]b
B51 [100]b
Assigned type [%]
NMDP
2
1
1
2
2
2823
Cells
tested
B51
B51
B52
Assignment
IHWS13 data
32
Cells
tested
B52 B15
B52
B52
B52
B52
B51
B51
B51
B51
B51
B51
B51
B51
NT
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
B51
NT
Not assignede
B51
NT
Not assignede
B51
B51
B51
B51
Training B5 B52
Assigned
type >0.55
NN
Normal B52
NN: B5, B51
NN: B44, B12, B53
Comments
137
138
Expert
assigned
B52
B52
B52
B52
B52
B53
B53
B53/B35
B53
B53
B53/B51
B53
B53
B53
B53
B53
B53
B53
B54
B54
B22
B54
Not expressed
Undefined
B54
Not expressed
Undefined
B54
B54
Undefined
HLA allele
B*5207
B*5208
B*5209
B*5210
B*5211
B*5301
B*5302
B*5303
B*5304
B*5305
B*5306
B*5307
B*5308
B*5309
B*5310
B*5311
B*5312
B*5313
B*5401
B*5402
B*5403
B*5404
B*5405N
B*5406
B*5407
B*5408N
B*5409
B*5410
B*5411
B*5412
Table 2 Continued
B54(22)
Null
Null
B54(22)
B53
B54(22)
B53
B52(5)
B52(5)
B53
WHO
assigned
B54 [8894]a
B53 [9194]a
Assigned type [%]
25
Cells tested
B53 [100]b
B54 [67], B55 [10],

B22 [3], B56 [2],
blank [9]
631
B53 [100]b
6
2
2
3054
Cells
tested
B53 [86], B35 [5],

B51 [1]
B53 [83]b
B35 [100]b
B53 [100]b
Assigned type [%]
NMDP
B54
B51
B53
Assignment
IHWS13 data
20
20
Cells
tested
B54
B54 B56
B54
NT
Not assignede
B54
NT
Not assignede
B54
B54
Not assignede
B53
B53
B53
B53
B53
B53
Training B22 B54
Not assignede
B53
B53
B53
Not assignede
B53
B52
B52
B52
B52
B52
Training B53
Assigned
type >0.55
NN
NN: B54, B22
NN: B54, B22
NN: B22
B53x51, long B53,

extra reactivity with
some B51 sera
some B37 CREG
sera; NN: B51, B5
NN: B35, B53

Long B53, some B5
sera reactive
Comments

Expert
assigned
B54
B55
B55
B55
B55
B55
B54
B56
B22
B55
B55
B55
B55
Undefined
B55
B55
B55
Undefined
B55
B22
B55
B22
B55
B55
B55
B55
B55
B56
HLA allele
B*5413
B*5501
B*5502
B*5503
B*5504
B*5505
B*5507
B*5508
B*5509
B*5510
B*5511
B*5512
B*5513
B*5514
B*5515
B*5516
B*5517
B*5518
B*5519
B*5520
B*5521
B*5522
B*5523
B*5524
B*5525
B*5526
B*5527
B*5601
Table 2 Continued
B55(22)
B22
B55(22)
B22
B55(22)
B56(22)
B56(22)
B22
B22
B54(22)
B56 [9496]
B55(22)c
B55(22)
B55 [8997]
B55 [8996]a
Assigned type [%]
B55(22)
B55(22)
WHO
assigned
4
6
Cells tested
B55 [100]b
B55 [100]b
B55 [100]b
B56 [72], B22 [5], B55

[3], blank [8]
B55 [80], B56 [7],

B22 [7]b
B22 [100]b
B55 [25], B54 [25],
B56 [25], blank
[25]b
B55 [92], B22 [5]

B55 [84], B54 [3],
B22 [2]
B55 [100]b
Assigned type [%]
NMDP
671
1
4
15
453
309
Cells
tested
B56
B56
B55
B55
Assignment
IHWS13 data
23
21
11
Cells
tested
B22
B55
B55
B55
Not assignede
B55
B55
B55
Not assignede
B55
B22f
B55
B22f
B55
B55
B55
B55
B55
Training B22 B56
B56
B55
B55
B22f
B22
B55
B54
Training B22 B55
Training B22 B55
Assigned
type >0.55
NN
NN: B56
NN: B55
B55v
NN: B22, B55
Short B22, B7 CREG

sera positive,
negative with B55
and B56 sera
NN: B54
B55x67, some Bw6

sera negative
Comments
139
140
B56
B78
B56
B56
B56
B55
B*5605
B*5606
B*5607
B*5608
B*5609
B*5610
B57
B56
B*5604
B*5702
B22/15
B*5603
B56
B22
B56
B56
B56
B56
B56
Undefined
Not expressed
B56
B57
B56
B*5602
B*5611
B*5612
B*5613
B*5614
B*5615
B*5616
B*5617
B*5618
B*5619N
B*5620
B*5701
Expert
assigned
HLA allele
Table 2 Continued
B57(17)
B56(22)
B55(22)
B56(22)
B56(22)
Null
B56(22)
B57(17)
B55(22)
B56(22)
B56(22)
B78
B56(22)
B22
B56(22)
WHO
assigned
B57 [8798], B58

[17], B17 [16]a
B57 [9596]a
B56 [8893], B22

[15]a
Assigned type [%]
12
Cells tested
Blank [100]b
B57 [92], B17 [5],

B58 [2]
B57 [78], B17 [8]
65
3670
Blank [100]b
28
17
Cells
tested
B56 [82], B54 [4], B22

[4], blank [11]b
B56 [63], B55 [12],

blank [25]b
B56 [65], B22 [6],
blank [12]b
Assigned type [%]
NMDP
B57
B57
B56
B56
B56
B56
B56
Assignment
IHWS13 data
28
Cells
tested
Training B17 B57
B56
B22
B56
B56
B56
B56
B56
Not assignede
NT
B56
Training B17 B57
B56
B56
B55
Not assignede
B22
B22
B56
Not assignede
Training B22 B56
Assigned
type >0.55
NN
ihw13: short B57
NN: B22
Short B22, reactive

with B54 1 55 sera,
negative with B55
1 7 sera
Short B56
B22 variant, B55, B56

sera negative, B15
1 46 1 70 sera
reactive; in Asians
Short B56s, some
B56 and B22 sera
negative
Short B56
B78 variant, some
B35 and B15 CREG
sera positive, all
B22 sera negative
B56 Bw4, some B7
sera positive;
ihw13: B56 Bw4;
NN: B56, B22
Comments

Expert
assigned
B57
B57
B57
B57
B57
B57
B57
B57
B57
B57
B57
B58
B58
B58
B58
B58
B58
B17/B5
B17
Not expressed
B58
B58
B58
B58
B58
B59
B59
B67
Undefined
HLA allele
B*5703
B*5704
B*5705
B*5706
B*5707
B*5708
B*5709
B*5710
B*5711
B*5712
B*5713
B*5801
B*5802
B*5804
B*5805
B*5806
B*5807
B*5808
B*5809
B*5810N
B*5811
B*5812
B*5813
B*5814
B*5815
B*5901
B*5902
B*6701
B*6702
Table 2 Continued
Null
B59
B59
B67
B17
B58(17)
B58(17)
B57(17)
B57(17)
B57(17)
WHO
assigned
B59 [9295]a
B67 [8690], B39

[511]a
B58 [8293]a
25
Cells tested
B58 [90100]a
B57 [9698]
Assigned type [%]
B59 [45], blank [41]
B39 [43], B67 [32],

B55 [8], blank [11]
B39 [100]b
B57 [100]b
B58 [79], B57 [8],

B17 [4]
B58 [72], B57 [12],
B17 [3]
B58 [100]b
B58 [100]b
B57 [85], B17 [6],

B58 [6]
B57 [67], B17 [7]
B57 [100]b
Assigned type [%]
NMDP
123
81
837
2096
32
3
412
Cells
tested
B59
B67
B58
B58
B57
B57
Assignment
IHWS13 data
10
28
Cells
tested
Not assignede
B58
NT
B58
B58
B58
B58
B58
Training B59
B59
Training B67
B58
B58
B58
B58
B5
Training B17 B58
B57
B57
B57
B57
B57
Training B17 B58
B57
B57
B57
B57
B57
Training B17 B57
Assigned
type >0.55
NN
ihw13: pattern
included in B22
NN: B67
B17 and some B5

sera reactive; NN:
B17
B57
Bw4 sera negative,

only strongly
reactive with B15 1
57 sera
ihw13: short B57
Comments
141
142
B73
B78
B78
B78
B35
Undefined
B81
B81
B82
B82
Undefined
B*7301
B*7801
B*7802
B*7803
B*7804
B*7805
B*8101
B*8102
B*8201
B*8202
B*8301
B82
B81
B81
B78
B78
B73
WHO
assigned
B82 [23], B81 [19],

B8201 [11], B56
[5], B22 [3], B42 [3]a
B81 [8190], B7
[1018], B48 [03]a
B81 [8990], B7 [10],
B48 [03], B60
[23]a
B8201 [28], B22 [9]
B78 [8390], B35

[19], B51 [16]
B73 [8187]
Assigned type [%]
12
Cells tested
146
B45 [33], blank [67]b
B45 [100]b
657
210
106
Cells
tested
Blank [68], B45 [4],

B70 [4], B82 [3],
B65 [3]
B78 [41], B35 [15],

B51 [10], B70 [4],
blank [19]
B78 [25], B35 [25],
B51 [25]b
B35 [100]b
B7 [76], B81 [8]
Blank [69], B73 [22]
Assigned type [%]
NMDP
B82
B82
B81
B78
B73
Assignment
IHWS13 data
Cells
tested
Not assignede
B56
B56
B81
B78
Not assignede
Not assignede
Training B81
B78
Training B78
Training B73
Assigned
type >0.55
NN

some B45 and B22
sera; ihw13:
pattern almost
included in B55
NN B35
NN B52
ihw13: pattern similar

to B2708
Comments
a
b
Updated NMDP data. In some cases the information reported in previous dictionaries has changed. Cells have been excluded from this study in some cases because their HLA typing has changed.
c
d
e
f
g
Ref 1316, 2957, 62.
Expert
assigned
HLA allele
Table 2 Continued

Expert
assigned
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1/blank
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
HLA allele
Cw*0102
Cw*0103
Cw*0104
Cw*0105
Cw*0106
Cw*0107
Cw*0108
Cw*0109
Cw*0110
Cw*0111
Cw*0112
Cw*0113
Cw*0114
Cw*0115
Cw*0116
Cw*0117
Cw*0118
Cw*0119
Cw*0202
Cw*0203
Cw*0204
Cw*0205
Cw*0206
Cw*0207
Cw*0208
Cw*0209
Cw*0210
Cw*0211
Cw*0212
Cw*0213
Cw*0214
Cw*0215
Cw*0216
Cw*0217
Cw1
Cw2
Cw2
Cw2
Cw1
Cw1
WHO
assigned
Cw2 [6276]a
Cw1 [5575]
Assigned type [%]
27
76
Cells
tested
Table 3 HLA-C alleles and their serologic designationsg
Cw2 [91]
Cw2 [100]b
Cw2 [75]b
Cw1 [92]
Cw1 [100]b
Cw1 [100]b
Assigned type [%]
NMDP
382
1
260
1
Cells
tested
67
104
Cells
tested
Cw2
Cw1
Assignment
IHWS13 data
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Training Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Cw2
Training Cw1
Cw1
Cw1
Cw1
Cw1
Cw1
Assigned
type >0.55
NN
Short Cw1
Cw blank, the HLA

club cell
exchange: nine
laboratories
performing
serology
Comments
143
144
Expert
assigned
Cw2
Cw10
Cw9
Cw10
Cw3
Cw10
Cw3
Cw10
Cw10
Cw3
Cw9
Cw9
Cw9
Cw10
Undefined
Blank
Cw10
Cw9
Cw3
Not expressed
Cw9
Undefined
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw9
HLA allele
Cw*0218
Cw*0302
Cw*0303
Cw*0304
Cw*0305
Cw*0306
Cw*0307
Cw*0308
Cw*0309
Cw*0310
Cw*0311
Cw*0312
Cw*0313
Cw*0314
Cw*0315
Cw*0316
Cw*0317
Cw*0318
Cw*0319
Cw*0320N
Cw*0321
Cw*0322Q
Cw*0323
Cw*0324
Cw*0325
Cw*0326
Cw*0327
Cw*0328
Cw*0329
Cw*0330
Table 3 Continued
Cw3
Cw10(w3)
Cw10(w3)
Cw3
Null
Cw3
Cw3
Cw10(w3)c
Cw3
Cw3c
Cw10(w3)
Cw9(w3)
Cw10(w3)
WHO
assigned
Cw3 [4567], Cw10

[613]a
Cw3 [5568], Cw9
[815]a
Cw3 [5269], Cw9
[011], Cw10
[312]a
Cw3 [48], Cw10 [7]a
Cw3 [52], Cw10 [6]
Cw3 [4459], Cw10

[36]
Assigned type [%]
1
1
62
38
13
Cells
tested
Cw3 [100]b
12
16
1
Cw3 [83], blank [17]b

Cw3 [75], blank [25]b
Cw3 [100]b
Cw3 [100]b
Cw3 [100]b
603
446
41
Cells
tested
Cw3 [92], Cw10 [3],

Cw9 [1]
Cw3 [80], Cw9 [6]
Cw3 [69], Cw10 [5]
Assigned type [%]
NMDP
Cw10
Cw10
Cw9
Cw10
Assignment
IHWS13 data
51
75
11
Cells
tested
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw9
Cw10
Cw9
Cw10
NT
Cw9
Cw9
Cw10
Cw9
Cw9
Cw9
Cw10
Not assignedd
Cw3
Cw10
Cw10
Cw10
Cw10
Cw10
Training Cw3 Cw10
Training Cw3 Cw9
Cw2
Cw10
Assigned
type >0.55
NN
Not expected to be
expressed
NN: Cw3, Cw10

Cw3, w9, w10 sera
negative; NN:
Cw10
ihw13: short pattern
Comments

Expert
assigned
Cw9
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw9
Cw10
Cw10
Cw4
Cw4/Cw6
Cw4
Cw4
Cw4/Cw6
Cw4
Cw4
Not expressed
Cw4
Undefined
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
HLA allele
Cw*0331
Cw*0332
Cw*0333
Cw*0334
Cw*0335
Cw*0336
Cw*0337
Cw*0338
Cw*0339
Cw*0340
Cw*0341
Cw*0401
Cw*0403
Cw*0404
Cw*0405
Cw*0406
Cw*0407
Cw*0408
Cw*0409N
Cw*0410
Cw*0411
Cw*0412
Cw*0413
Cw*0414
Cw*0415
Cw*0416
Cw*0417
Cw*0418
Cw*0419
Cw*0420
Cw*0421
Cw*0423
Cw*0424
Cw*0425
Table 3 Continued
Cw4c
Null
Cw4
Cw4
Cw3
Cw3
Cw4
WHO
assigned
Cw6 [2733], Cw4

[2025], C403
[23]a
Cw4 [5476]a
Cw4 [1633], Cw6
[726], C403
[38]a
Assigned type [%]
107
35
Cells
tested
Blank [100]b
Cw4 [100]b
be
1
1
2
1
4
2
Cw4 [75], blank [25]b

Cw4 [100]b
Cw4 [100]b
736
7
Cells
tested
Cw4 [98]
Blank [100]b
Assigned type [%]
NMDP
Cw4
Blank
Cw4
Cw4
Assignment
IHWS13 data
114
11
Cells
tested
Cw4
Cw4
NT
Cw4
Not assignedd
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Cw4
Not assignedd
Cw9
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw10
Cw9
Cw10
Cw10
Training Cw4
Not assignedd
Assigned
type >0.55
NN
Normal Cw4
NN: Cw4
NN: Cw4
NN: Cw4; Cw4/6

variant; ihw13: Cw6
or blank, only Cw4
1 6 sera reactive
Comments
145
146
Expert
assigned
Cw4
Cw4
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Not expressed
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Undefined
Cw6
Cw6
Cw6
Cw6
Not expressed
Cw7
Cw7
Cw7
HLA allele
Cw*0426
Cw*0427
Cw*0501
Cw*0502
Cw*0503
Cw*0504
Cw*0505
Cw*0506
Cw*0507N
Cw*0508
Cw*0509
Cw*0510
Cw*0511
Cw*0512
Cw*0513
Cw*0514
Cw*0515
Cw*0516
Cw*0517
Cw*0602
Cw*0603
Cw*0604
Cw*0605
Cw*0606
Cw*0607
Cw*0608
Cw*0609
Cw*0610
Cw*0611
Cw*0612
Cw*0613
Cw*0614
Cw*0615
Cw*0616N
Cw*0701
Cw*0702
Cw*0703
Table 3 Continued
Cw6
Null
Cw7
Cw7
Cw5
Cw5
Null
Cw6
WHO
assigned
Cw7 [5273]a
Cw7 [5173]a
Cw5 [5063]a
Cw6 [5171]a
Assigned type [%]
36
110
13
44
Cells
tested
Cw5 [83], blank [15]

Cw5 [100]b
Blank [100]b
Cw5 [100]b
Cw6 [74], Cw4 [1],

blank [12]
Cw6 [100]b
Cw6 [100]b
Blank [100]b
Cw7 [74], blank [20]

Cw7 [68], blank [14]
Assigned type [%]
NMDP
1
2
304
976
579
2
665
Cells
tested
Cw7
Cw7
Cw5
Cw6
Assignment
IHWS13 data
129
144
69
104
Cells
tested
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Cw6
Not assignedd
Cw6
Cw6
Cw6
Cw6
NT
Training Cw7
Training Cw7
Cw7
Cw4
Cw4
Training Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
NT
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Cw5
Training Cw6
Assigned
type >0.55
NN
NN: Cw6
Comments

Expert
assigned
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Not expressed
Not expressed
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
HLA allele
Cw*0704
Cw*0705
Cw*0706
Cw*0707
Cw*0708
Cw*0709
Cw*0710
Cw*0711
Cw*0712
Cw*0713
Cw*0714
Cw*0715
Cw*0716
Cw*0717
Cw*0718
Cw*0719
Cw*0720
Cw*0721
Cw*0722
Cw*0723
Cw*0724
Cw*0725
Cw*0726
Cw*0727
Cw*0728
Cw*0729
Cw*0730
Cw*0731
Cw*0732N
Cw*0733N
Cw*0734
Cw*0735
Cw*0736
Cw*0737
Cw*0738
Cw*0739
Table 3 Continued
Cw7
Null
Null
Cw7
Cw7
Cw7
Cw7
Cw7c
Cw7
Cw7
Cw7
Cw7
WHO
assigned
Cw7 [5972]
Cw7 [6276]
Cw7 [61%] allele

typed outside
primary cell range
Cw7 [73]a
Assigned type [%]
14
Cells
tested
Cw7 [67], blank [33]b
be
54
3
1
1
1
1
Cells
tested
Cw7 [64], blank [24]
Cw7 [67], blank [33]b

Blank [100]b
Cw7 [100]b
Cw7 [100]b
Cw7 [100]b
Blank [100]b
Assigned type [%]
NMDP
Cw7
Cw7
Assignment
IHWS13 data
30
2
Cells
tested
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
NT
NT
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Assigned
type >0.55
NN
Comments
147
148
Expert
assigned
Cw7
Undefined
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw8
Cw8
Cw8
Cw8
Cw8
Cw8
Cw8
Cw8
Cw8
Undefined
Undefined
Cw8
Cw8
Cw8
Undefined
Undefined
Blank
Undefined
Undefined
Undefined
Undefined
Undefined
HLA allele
Cw*0740
Cw*0741
Cw*0742
Cw*0743
Cw*0744
Cw*0745
Cw*0746
Cw*0747
Cw*0748
Cw*0749
Cw*0801
Cw*0802
Cw*0803
Cw*0804
Cw*0805
Cw*0806
Cw*0807
Cw*0808
Cw*0809
Cw*0810
Cw*0811
Cw*0812
Cw*0813
Cw*0814
Cw*1202
Cw*1203
Cw*1204
Cw*1205
Cw*1206
Cw*1207
Cw*1208
Cw*1209
Table 3 Continued
Cw8
Cw8
Cw8c
Cw7
Cw7
Cw7
Cw7
Cw8
WHO
assigned
Blank [59], Cw7 [4]

Blank [100]b
30a
4a
Blank
Cw8 [67], blank [29]

Blank [100]b
Cw8 [100]b
Blank [94]
21
4
4
11a
Cw8 [5566]a
Cw8 [816]a
Cw8 [4357]a
Blank, no Cw antigen
reported by more
than 5% of the
laboratories
Blank
Cw8 [41], blank [34]
Assigned type [%]
62
Cells
tested
NMDP
Cw8 [4066]a
Assigned type [%]
238
234
3
2
85
31
Cells
tested
Blank
Cw8
Blank
Blank
Cw8
Assignment
IHWS13 data
75
30
2
27
40
Cells
tested
Cw6
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Training Cw8
Cw8
Cw8
Cw8
Cw8
Cw8
Cw8
Not assignedd
Cw5
Not assignedd
Cw8
Cw8
Cw8
Not assignedd
Cw7
Cw8
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw7
Cw8
Assigned
type >0.55
NN
NN: Cw2, Cw6
NN: Cw6
NN: Cw2, Cw6
ihw13: reactive with

broad Cw reagents
ihw13: reactive with

broad Cw reagents
NN: Cw8, Cw7
NN: Cw8, Cw7
ihw13: pattern
different from
Cw*0802
Comments

Expert
assigned
Undefined
Undefined
Undefined
Undefined
Cw7
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Cw1/blank
Cw1/blank
Undefined
Cw1
Undefined
Not expressed
Cw1
Undefined
Undefined
Undefined
Undefined
Undefined
Cw3
Undefined
Undefined
Undefined
Undefined
Undefined
HLA allele
Cw*1210
Cw*1211
Cw*1212
Cw*1213
Cw*1214
Cw*1215
Cw*1216
Cw*1217
Cw*1218
Cw*1219
Cw*1220
Cw*1221
Cw*1402
Cw*1403
Cw*1404
Cw*1405
Cw*1406
Cw*1407N
Cw*1408
Cw*1502
Cw*1503
Cw*1504
Cw*1505
Cw*1506
Cw*1507
Cw*1508
Cw*1509
Cw*1510
Cw*1511
Cw*1512
Table 3 Continued
Null
WHO
assigned
Blank
reported by more
than 5% of the
laboratories
reported by more
than 5% of the
laboratories
Blank
Blanka
Assigned type [%]
1
1
107
2
2
29
1
Blank [100]b
Blank [100]b
Blank [90]
Blank [100]b
Blank [100]b
Blank [62], Cw7 [24],
Cw2 [10]b
Blank [100]b
Blank [100]b
Blank [100]b
31a
11a
11
Blank [100]b
5a
93
Cells
tested
Blank [93]
Assigned type [%]
NMDP
19a
Cells
tested
Blank
Blank
Blank
Cw1
Cw1
Assignment
IHWS13 data
56
2
5
10
36
Cells
tested
d
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Cw3f
Not assignedd
Not assignedd
Cw1
Not assignedd
NT
Cw1
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assigned
Not assignedd
Not assignedd
Not assignedd
Cw7
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Cw1
Assigned
type >0.55
NN
NN: Cw2, Cw3, Cw10

NN: Cw3, Cw9, Cw2
NN: Cw10, Cw3, Cw2

NN: Cw10, Cw3, Cw2
NN: Cw3, Cw2
NN: Cw10, Cw3,
Cw2, Cw5
NN: Cw10, Cw3, Cw2
NN: Cw10
NN: Cw10, Cw3,
Cw2, Cw5
NN: Cw3, Cw2
NN: Cw1
NN: Cw4, Cw1
ihw13: short Cw1;

NN: Cw1
NN: Cw2, Cw5

ihw13: short Cw1
NN: Cw7
NN: Cw7
Comments
149
150
WHO
assigned
Cw6 [3249], Cw4

[26]a
Cw7 [223]a
Blanka
C17 [2743], Cw7

[622]a
C17 [3144], Cw7

[1020]a
Cw6 [3042]a
Assigned type [%]
36
3
25
Cells
tested
Cw4 [40], Cw6 [40],

Cw7 [20]b
Cw6 [100]b
276
22
10
28
Blank [100]b
Blank [94]
Blank [97]
Blank [100]b
Blank [82], Cw7 [18]b
Blank [100]b
Cells
tested
Assigned type [%]
NMDP
Blank
Blank
Blank
Assignment
IHWS13 data
57
5
2
Cells
tested
NN: Cw6, Cw4

NN: Cw6, Cw4
NN: Cw6, Cw4
Not assignedd
Not assignedd
NN: Cw2, Cw6
NN: Cw2, Cw6

NN: Cw1
NN: Cw7
NN: Cw7
NN: Cw10, Cw3, Cw2

NN: Cw10, Cw3
NN: Cw10, Cw3, Cw2
NN: Cw10, Cw3, Cw2
NN: Cw3, Cw2
NN: Cw3, Cw2
NN: Cw10
NN: Cw10, Cw3, Cw2
Comments
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Cw3f
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Not assignedd
Assigned
type >0.55
NN
b
c
d
e
f
g
Ref 14, 58, 59.
Undefined
Undefined
Cw6/blank
Cw*1704
Cw*1801
Cw*1803
Undefined
Cw7/blank
Cw*1702
Cw*1703
Cw6/blank
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Cw3
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Cw7/blank
Cw*1513
Cw*1514
Cw*1515
Cw*1516
Cw*1517
Cw*1518
Cw*1519
Cw*1520
Cw*1521
Cw*1601
Cw*1602
Cw*1604
Cw*1606
Cw*1607
Cw*1608
Cw*1609
Cw*1701
Cw*1802
Expert
assigned
HLA allele
Table 3 Continued

Expert assigned
DR1
DR1
DR103/DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR17
DR18
DR18
DR17
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR17
DR3
HLA allele
DRB1*0101
DRB1*0102
DRB1*0103
DRB1*0104
DRB1*0105
DRB1*0106
DRB1*0107
DRB1*0108
DRB1*0109
DRB1*0110
DRB1*0111
DRB1*0112
DRB1*0113
DRB1*0114
DRB1*0115
DRB1*0116
DRB1*0301
DRB1*0302
DRB1*0303
DRB1*0304
DRB1*0305
DRB1*0306
DRB1*0307
DRB1*0308
DRB1*0309
DRB1*0310
DRB1*0311
DRB1*0312
DRB1*0313
DRB1*0314
DRB1*0315
DRB1*0316
DR3
DR3
DR3d
DR17(3)d
DR17(3)d
DR3
DR3
DR3
DR17(3)
DR18(3)
DR18(3)
DR1
DR1
DR1
DR1
DR17(3)
DR1
DR1
DR103
WHO assigned
Table 4 HLA-DRB1 alleles and their serologic designations
DR17 [50], DR3

[4450]a
DR3 [3840],
DR17 [2025],
DR18 [010]a
21
2
5
DR1 [95100]a
DR1 [8695]
DR103 [7580],
DR1 [917]a
DR17 [3370],
DR3 [2050],
DR18 [011]a
DR18 [6267],
DR3 [2735]
10
36
Cells tested
Assigned type [%]
DR18 [66], DR3

[24], DR17 [3]
DR18 [50], DR17
[50]b
DR3 [57], DR17
[29]b
DR3 [100]b
DR3 [100]b
DR3 [100]b
DR1 [97]
DR1 [95]
DR1 [56], DR103
[12], blank [18]
DR1 [100]b
DR17 [64], DR3

[33]
Assigned type [%]
NMDP
1
1
317
9698
6317
2035
1186
Cells tested
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
Training DR3
DR18
DR18
Training DR1
Training DR1
Training DR1
DR103
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
DR1
Not assignedc
DR1
DR1
DR1
Training DR3
DR17
Assigned type >0.55
NN
NN: DR1
Comments
151
152
Expert assigned
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR3
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
HLA allele
DRB1*0317
DRB1*0318
DRB1*0319
DRB1*0320
DRB1*0321
DRB1*0322
DRB1*0323
DRB1*0324
DRB1*0325
DRB1*0326
DRB1*0327
DRB1*0328
DRB1*0329
DRB1*0330
DRB1*0331
DRB1*0332
DRB1*0333
DRB1*0335
DRB1*0401
DRB1*0402
DRB1*0403
DRB1*0404
DRB1*0405
DRB1*0406
DRB1*0407
DRB1*0408
DRB1*0409
DRB1*0410
DRB1*0411
DRB1*0412
DRB1*0413
DRB1*0414
DRB1*0415
DRB1*0416
DRB1*0417
DRB1*0418
DRB1*0419
DRB1*0420
Table 4 Continued
DR4
DR4
DR4
DR4
DR3
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
WHO assigned
DR4 [100]a
DR4 [84100]
DR4 [97100]a
DR4 [95100]a
DR4 [94100]a
DR4 [89100]
DR4 [97100]a
DR4 [100]a
DR4 [100]
DR4 [94100]a
DR4 [84100],
DR11 [20]a
DR4 [100]
Assigned type [%]
13
4
9
20
13
3
7
1
3
3
Cells tested
5118
1029
748
2164
505
83
846
258
11
29
76
1
3
1
3
1
1
DR17 [100]b
DR4 [98]
DR4 [92]
DR4 [92]
DR4 [89]
DR4 [91]
DR4 [89]
DR4 [86]
DR4 [86]
DR4 [100]b
DR4 [84]
DR4 [93]
DR4 [100]b
DR4 [100]b
DR4 [100]b
DR4 [67]b
DR4 [100]b
DR4 [100]b
be
Cells tested
Assigned type [%]
NMDP
DR4
DR4
DR4
DR4
DR4
DR3
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR17
DR18
DR17
DR18
DR17
DR17
DR17
DR17
DR18
Training DR4
Training DR4
Training DR4
Training DR4
Training DR4
DR4
Training DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
Assigned type >0.55
NN
DR4x11
Comments

Expert assigned
DR4
DR4/DR3
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
HLA allele
DRB1*0421
DRB1*0422
DRB1*0423
DRB1*0424
DRB1*0425
DRB1*0426
DRB1*0427
DRB1*0428
DRB1*0429
DRB1*0430
DRB1*0431
DRB1*0432
DRB1*0433
DRB1*0434
DRB1*0435
DRB1*0436
DRB1*0437
DRB1*0438
DRB1*0439
DRB1*0440
DRB1*0441
DRB1*0442
DRB1*0443
DRB1*0444
DRB1*0445
DRB1*0446
DRB1*0447
DRB1*0448
DRB1*0449
DRB1*0450
DRB1*0451
DRB1*0452
DRB1*0453
DRB1*0454
DRB1*0455
DRB1*0456
DRB1*0457
DRB1*0458
DRB1*0459
Table 4 Continued
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4d
DR4
WHO assigned
DR4 [100]
DR4 [100]a
DR4 [94100]a
Assigned type [%]
2
2
Cells tested
DR4 [100]b
DR4 [100]b
DR4 [100]b
DR4 [100]b
be
Cells tested
Assigned type [%]
NMDP
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
DR4
Assigned type >0.55
NN
Short DR4
DR4x3
Comments
153
154
Expert assigned
DR4
DR4
DR4
DR4
DR4
DR7
DR7
DR7
DR7
DR7
DR7
DR7
DR7
Not expressed
DR7
DR7
DR7
DR7
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
undefined
HLA allele
DRB1*0460
DRB1*0461
DRB1*0462
DRB1*0463
DRB1*0464
DRB1*0701
DRB1*0703
DRB1*0704
DRB1*0705
DRB1*0706
DRB1*0707
DRB1*0708
DRB1*0709
DRB1*0710N
DRB1*0711
DRB1*0712
DRB1*0713
DRB1*0714
DRB1*0801
DRB1*0802
DRB1*0803
DRB1*0804
DRB1*0805
DRB1*0806
DRB1*0807
DRB1*0808
DRB1*0809
DRB1*0810
DRB1*0811
DRB1*0812
DRB1*0813
DRB1*0814
DRB1*0815
DRB1*0816
DRB1*0817
DRB1*0818
DRB1*0819
DRB1*0820
Table 4 Continued
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR4
DR7
DR7
DR7
DR7
Null
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
WHO assigned
43
7
4
12
9
4
1
2
2
DR8 [8994]a
DR8 [7478]a
DR8 [85]a
Cells tested
DR7 [93100]a
DR7 [100]
DR8 [91100]a
DR8 [100]a
DR8 [96100]
DR8 [88100]a
DR8 [96100]
DR8 [89]
DR8 [94100]a
Assigned type [%]
DR7 [99]
DR8 [95]
DR8 [96]
DR8 [88], DR12 [3]
DR8 [93]
DR8 [83]b
DR8 [95]b
DR8 [100]b
DR8 [100]b
DR8 [67], DR12
[22]b
DR8 [100]b
DR8 [100]b
Assigned type [%]
NMDP
10
7390
1076
265
230
186
6
21
3
2
9
Cells tested
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
Not assignedc
DR4
DR4
DR4
DR4
DR4
Training DR7
DR7
DR7
DR7
DR7
DR7
DR7
DR7
NT
DR7
DR7
DR7
DR7
Training DR8
Training DR8
Training DR8
Training DR8
DR8
DR8
DR8
DR8
DR8
DR8
Assigned type >0.55
NN
NN: DR8
DR8 variant
Comments

Expert assigned
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8/DR11
Undefined
DR9
DR9
DR9
DR9
DR9
DR9
DR10
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
HLA allele
DRB1*0821
DRB1*0822
DRB1*0823
DRB1*0824
DRB1*0825
DRB1*0826
DRB1*0827
DRB1*0828
DRB1*0829
DRB1*0830
DRB1*0831
DRB1*0832
DRB1*0901
DRB1*0902
DRB1*0903
DRB1*0904
DRB1*0905
DRB1*0906
DRB1*1001
DRB1*1101
DRB1*1102
DRB1*1103
DRB1*1104
DRB1*1105
DRB1*1106
DRB1*1107
DRB1*1108
DRB1*1109
DRB1*1110
DRB1*1111
DRB1*1112
DRB1*1113
DRB1*1114
Table 4 Continued
DR11(5)
DR11(5)
DR11(5)
2
3
3
1
DR11 [91100]a
DR11 [100]
DR11 [8790],
DR13 [78],
DR5 [45]
DR11 [93]a
DR11 [94100]a
DR11(5)d
DR11(5)
DR11(5)
15
6
2
13
2
DR11 [88100]a
DR11 [89100]
DR11 [84100]
DR11 [87100]a
DR11 [90100]a
DR11(5)
DR11(5)
DR11(5)
DR11(5)
DR11(5)
DR11(5)
Cells tested
19
14
Assigned type [%]
DR9 [89100]
DR10 [87100]a
DR11(5)
DR9
DR9
DR10
WHO assigned
DR11 [100]b
DR11 [86]b
DR11 [100]b
DR11 [75], DR5

[25]b
DR11 [100]b
DR11 [90], DR5
[10]b
be
DR9 [95]
DR10 [90], DR1

[4], blank [2]
DR11 [92], DR5 [5]
DR11 [89], DR5 [3]
DR11 [89], DR5 [4]
DR11 [87], DR5 [4]
DR11 [100]b
DR5 [79], DR11
[21]b
DR11 [100]b
Assigned type [%]
NMDP
5
7
2
2
10
1
4
3474
430
397
2119
3
14
1058
894
Cells tested
DR11
DR11
DR11
DR11
DR11
DR11
Training DR11
Not assignedc
Training DR11
Training DR11
Training DR11
Training DR11
DR11
DR11
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
DR8
Not assignedc
Not assignedc
Training DR9
DR9
DR9
DR9
DR9
DR9
Training DR10
Assigned type >0.55
NN
DR11x14
DR11x13
DR11x3; NN:
DR17, DR3, DR11
NN: DR8, DR11

NN: DR8, DR12
Comments
155
156
Expert assigned
DR11
DR11/DR13
DR14
DR11
DR11
DR11
DR11
Undefined
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
HLA allele
DRB1*1115
DRB1*1116
DRB1*1117
DRB1*1118
DRB1*1119
DRB1*1120
DRB1*1121
DRB1*1122
DRB1*1123
DRB1*1124
DRB1*1125
DRB1*1126
DRB1*1127
DRB1*1128
DRB1*1129
DRB1*1130
DRB1*1131
DRB1*1132
DRB1*1133
DRB1*1134
DRB1*1135
DRB1*1136
DRB1*1137
DRB1*1138
DRB1*1139
DRB1*1140
DRB1*1141
DRB1*1142
DRB1*1143
DRB1*1144
DRB1*1145
DRB1*1146
DRB1*1147
DRB1*1148
DRB1*1149
DRB1*1150
Table 4 Continued
DR11(5)
DR11(5)
DR11(5)
DR11(5)
DR11(5)
DR11(5)
DR11(5)/DR13
(6)d
DR11(5)
DR11(5)
DR11(5)
WHO assigned
DR11 [100]
DR11 [8897],
DR13 [12]a
DR11 [100]
Assigned type [%]
Cells tested
be
be
DR11 [50], DR6

[50]b
DR11 [100]b
Assigned type [%]
NMDP
1
1
Cells tested
Not assignedc
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR14f
DR11
DR11
DR11
DR11
DR11
DR11
Assigned type >0.55
NN
NN: DR11
DR11x13
DR11x13; DR11
(70), DR13 (30)
NN: DR6
Comments

Expert assigned
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR13
DR13
DR13
HLA allele
DRB1*1151
DRB1*1152
DRB1*1153
DRB1*1154
DRB1*1155
DRB1*1156
DRB1*1157
DRB1*1158
DRB1*1159
DRB1*1160
DRB1*1161
DRB1*1162
DRB1*1201
DRB1*1202
DRB1*1203
DRB1*1204
DRB1*1205
DRB1*1206
DRB1*1207
DRB1*1208
DRB1*1209
DRB1*1210
DRB1*1211
DRB1*1212
DRB1*1213
DRB1*1214
DRB1*1215
DRB1*1301
DRB1*1302
DRB1*1303
Table 4 Continued
DR13(6)
DR13(6)
DR12(5)
DR12(5)
DR12(5)
DR12(5)
DR13(6)
DR11(5)
DR12(5)
WHO assigned
DR12 [91100]
DR13 [90100],
DR6 [07]a
DR13 [8197],
DR6 [711]a
DR13 [5093],
DR6 [421],
DR1303
[011], DR14
[017], DR3
[08]
DR12 [85100],
DR13 [512]
Assigned type [%]
11
17
17
17
Cells tested
DR12 [83], DR5

[4], DR8 [2],
DR11 [2]
DR12 [89]
DR12 [100]b
DR12 [100]b
DR13 [81], DR6

[14], DR14 [1]
DR13 [74], DR6
[17], DR14 [2]
DR13 [69], DR6
[10], DR12 [3],
DR11 [3], DR5
[2], DR14 [2]
Assigned type [%]
NMDP
948
3081
162
4
3788
893
Cells tested
Training DR6 DR13
Training DR6 DR13
Training DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
DR12
Training DR6 DR13
DR11
DR14
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
DR11
Training DR12
Assigned type >0.55
NN
DR12x11
Comments
157
158
DR13
DR13
DR11
DR13
DRB1*1314
DRB1*1322
DRB1*1323
DRB1*1324
DR13
DRB1*1313
DR13/DR11
DR13
DRB1*1312
DRB1*1321
DR13
DRB1*1311
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DRB1*1307
DRB1*1308
DRB1*1309
DRB1*1310
DRB1*1318
DRB1*1319
DRB1*1320
DR13
DRB1*1306
DR13
DR13
DR13
DR13
DR13
DRB1*1304
DRB1*1305
DRB1*1315
DRB1*1316
DRB1*1317
Expert assigned
HLA allele
Table 4 Continued
DR13(6)d
DR13(6)
DR13(6)d
DR13(6)
DR13(6)
DR13(6)
DR13(6)
DR13 [83], DR6

[13]
DR13 [6977],
DR11 [015],
DR14 [09],
DR6 [05]a
DR13 [53], DR8

[41], DR11 [6]a
DR13 [8795],
DR6 [05]a
DR13 [84], DR6 [5]
DR13 [8095],
DR6 [715],
DR14 [010]a
DR13 [7290],
DR11 [028],
DR14 [010],
DR6 [06]a
DR13 [4862],
DR11 [1134],
DR6 [520],
DR14 [38]
DR13 [95]
Assigned type [%]
DR13(6)d
DR13(6)d
DR13(6)
DR13(6)
DR13(6)
DR13(6)
DR13(6)
DR13(6)
DR13(6)
WHO assigned
Cells tested
DR13 [50], blank

[50]b
DR13 [100]b
DR11 [50], blank

[50]b
DR13 [50], DR6

[13], DR12 [13],
DR11 [13]b
DR6 [50], blank

[50]b
DR13 [87]
DR13 [54], DR6
[12], DR11 [7],
DR12 [6], DR5
[4]
DR13 [88], DR6
[12]b
DR13 [100]b
DR13 [100]b
DR13 [100]b
DR13 [100]b
Assigned type [%]
NMDP
1
5
1
4
127
305
Cells tested
DR13f
DR13
DR11
DR11
Not assignedc
DR13
DR13
DR13
DR13
Not assignedc
DR11
DR6
DR13
DR11
Not assignedc
DR13
DR6f
DR13
DR13
DR13
DR6
Assigned type >0.55
NN
NN: DR6
NN: DR6
NN: DR6, DR11

NN: DR14
DR13x8; NN: DR8
DR52 negative;
NN: DR13, DR8
DR13x12
NN: DR13
NN: DR11, DR6
Comments

Expert assigned
DR11
DR14
DR13
DR13
DR13
Undefined
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR6
DR13
Undefined
DR13
DR11
Undefined
DR13
DR6
DR11
DR13
DR13
DR13
DR14
Undefined
DR6
DR13
HLA allele
DRB1*1325
DRB1*1326
DRB1*1327
DRB1*1328
DRB1*1329
DRB1*1330
DRB1*1331
DRB1*1332
DRB1*1333
DRB1*1334
DRB1*1335
DRB1*1336
DRB1*1337
DRB1*1338
DRB1*1339
DRB1*1340
DRB1*1341
DRB1*1342
DRB1*1343
DRB1*1344
DRB1*1345
DRB1*1346
DRB1*1347
DRB1*1348
DRB1*1349
DRB1*1350
DRB1*1351
DRB1*1352
DRB1*1353
DRB1*1354
DRB1*1355
DRB1*1356
DRB1*1357
Table 4 Continued
DR13(6)
DR13(6)
DR14(6)
DR13(6)
DR13(6)
DR13(6)
DR13(6)d
WHO assigned
DR13 [80], DR14

[10]a
DR13 [91100],
DR6 [05],
DR14 [04]a
DR13 [7290],
DR6 [09]a
Assigned type [%]
Cells tested
DR6 [100]b
Assigned type [%]
NMDP
Cells tested
DR13
DR13
DR13
DR13
DR13
DR6
DR13
Not assignedc
DR13
DR11
Not assignedc
DR13
DR6
DR11
DR13
DR13
DR13
Not assignedc
Not assignedc
DR6
DR13
DR13
DR13
DR13
DR13
DR13
DR13
Not assignedc
DR13
DR13
DR13
DR11
DR14
Assigned type >0.55
NN
NN: DR11
NN: DR8, DR6
NN: DR13
NN: DR8
NN: DR11
NN: DR13, DR6,

DR11
DR blank DR52
positive
Comments
159
160
DR1403/DR14
DR1404/DR14
DR14
DRB1*1404
DRB1*1405
DR13
DR13
DR13
DR14
DRB1*1376
DRB1*1378
DRB1*1379
DRB1*1401
DRB1*1403
DR13
DR11
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
Undefined
DRB1*1361
DRB1*1362
DRB1*1363
DRB1*1364
DRB1*1365
DRB1*1366
DRB1*1367
DRB1*1368
DRB1*1369
DRB1*1370
DRB1*1371
DRB1*1372
DRB1*1373
DRB1*1374
DRB1*1375
DR14
DR13
DR13
DR6
DRB1*1358
DRB1*1359
DRB1*1360
DRB1*1402
Expert assigned
HLA allele
Table 4 Continued
DR14(6)
DR1404
DR1403
DR14(6)
DR14(6)
DR13(6)
WHO assigned
DR14 [8489],
DR1404 [58],
DR6 [37], DR8
[010]
DR14 [7485],
DR6 [1115],
DR3 [013]
DR14 [91100],
DR6 [07]a
DR14 [5083],
DR6 [1217],
DR17 [815],
DR13 [019]
Assigned type [%]
18
Cells tested
DR14 [86], DR6

[10]
DR14 [72], DR6

[12]
DR14 [79], DR6
[8], DR1404 [3]
DR14 [74], DR6

[14], DR13 [3]
DR14 [61], DR6
[13], DR13 [9]
Assigned type [%]
NMDP
58
80
37
204
1942
Cells tested
DR14
DR14
DR14
Training DR6 DR14
DR13
DR13
DR13
Training DR6 DR14
DR13
DR11
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
DR13
Not assignedc
DR13
DR13
DR6
Assigned type >0.55
NN
NN: DR11, DR13,

DR6
DRB5*02
associated (60)
Comments

Expert assigned
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR8
DR6
DR6
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR6
DR14
DR14
DR14
HLA allele
DRB1*1406
DRB1*1407
DRB1*1408
DRB1*1409
DRB1*1410
DRB1*1411
DRB1*1412
DRB1*1413
DRB1*1414
DRB1*1415
DRB1*1416
DRB1*1417
DRB1*1418
DRB1*1419
DRB1*1420
DRB1*1421
DRB1*1422
DRB1*1423
DRB1*1424
DRB1*1425
DRB1*1426
DRB1*1427
DRB1*1428
Table 4 Continued
DR14(6)d
DR14(6)
DR14(6)
DR6
DR14(6)
DR14(6)
DR14(6)
DR6
DR6
DR8
DR14(6)
DR14(6)
DR14(6)
DR14(6)
DR14(6)
DR14(6)d
DR14(6)
DR14(6)
WHO assigned
DR14 [5784],
DR13 [829],
DR6 [414],
DR17 [06]a
DR14 [7683],
DR6 [410]
DR14 [59], DR6
[12], DR11 [12],
DR14x11 [9]
DR14 [5986],
DR6 [417],
DR13 [010]
DR14 [8889],
DR13 [05]
DR8 [50], DR14
[26], DR13 [8]
DR13 [28], DR14

[26], DR6 [19],
DR3 [11]
DR14 [8796],
DR6 [04]a
DR14 [94]
Assigned type [%]
Cells tested
16
DR14 [94]b
1
1
1
1
DR14 [100]b
DR13 [100]b
DR14 [100]b
Blank [100]b
DR6 [100]b
DR8 [100]b
DR14 [100]b
DR14 [100]b
DR6 [100]b
DR14 [50], DR6

[25]b
DR14 [100]b
117
Cells tested
DR14 [37], DR13

[22], DR6 [15]
Assigned type [%]
NMDP
DR14
DR14
DR14
DR6
DR14
DR6
DR14
DR14
DR14
DR14
DR6
DR13
DR6
DR8
DR14
DR14
DR14
Not assignedc
DR14
Not assignedc
DR14
DR14
Training DR6 DR14
Assigned type >0.55
NN
NN: DR14
Also typed as
DR13
DR14x13
DR14x13; DR13
weak, DR14
negative
DR8 1 DR52
NN: DR6
NN: DR4, DR14,

DR6
DR14x11; NN:
DR14
Comments
161
162
Expert assigned
DR14
DR6
DR14
DR14
DR6
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
Undefined
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR13/14
DR14
DR14
DR14
DR4/DR6
DR14
DR14
DR14
DR14
DR14
DR6
DR14
DR6
DR14
DR6
HLA allele
DRB1*1429
DRB1*1430
DRB1*1431
DRB1*1432
DRB1*1433
DRB1*1434
DRB1*1435
DRB1*1436
DRB1*1437
DRB1*1438
DRB1*1439
DRB1*1440
DRB1*1441
DRB1*1442
DRB1*1443
DRB1*1444
DRB1*1445
DRB1*1446
DRB1*1447
DRB1*1448
DRB1*1449
DRB1*1450
DRB1*1451
DRB1*1452
DRB1*1453
DRB1*1454
DRB1*1455
DRB1*1456
DRB1*1457
DRB1*1458
DRB1*1459
DRB1*1460
DRB1*1461
DRB1*1462
DRB1*1463
DRB1*1464
DRB1*1465
DRB1*1466
DRB1*1467
Table 4 Continued
DR14(6)
DR14(6)
DR14(6)
DR13(6)
DR14(6)
WHO assigned
DR14 [100]a
Assigned type [%]
Cells tested
DR14 [89]b
Assigned type [%]
NMDP
Cells tested
DR14
DR6
DR14
DR14
DR6
DR14
DR14
DR14
DR14
DR14
DR14
DR14
DR14
Not assignedc
DR14
DR14
DR14
DR14
DR14
DR14
DR14
Not assignedc
DR14
DR14
DR11
DR14
DR14
DR14
DR4
DR14
DR14
DR14
DR14
DR14
DR6f
DR14
DR6f
DR14
DR6f
Assigned type >0.55
NN
NN: DR14
NN: DR14
NN: DR14
NN: DR6
NN: DR14, DR6
NN: DR11
NN: DR14
Comments

Expert assigned
DR14
DR15
DR15
DR15
DR15
DR15
DR15
DR15
DR15
DR15
DR2
DR15
DR15
DR2
DR15
DR15
DR15
Not expressed
DR15
DR15
DR15
DR2
DR15
DR16
DR16
DR16
HLA allele
DRB1*1468
DRB1*1501
DRB1*1502
DRB1*1503
DRB1*1504
DRB1*1505
DRB1*1506
DRB1*1507
DRB1*1508
DRB1*1509
DRB1*1510
DRB1*1511
DRB1*1512
DRB1*1513
DRB1*1514
DRB1*1515
DRB1*1516
DRB1*1517N
DRB1*1518
DRB1*1519
DRB1*1520
DRB1*1521
DRB1*1522
DRB1*1601
DRB1*1602
DRB1*1603
Table 4 Continued
DR2
DR16(2)
DR2
Null
DR16(2)
DR15(2)
DR15(2)
DR15(2)d
DR15(2)d
DR15(2)
DR15(2)
DR15(2)
WHO assigned
DR15 [7590],
DR2 [019],
DR16 [013]a
DR15 [82100],
DR2 [014]a
DR15 [8194],
DR2 [313],
DR16 [06]a
DR15 [7691],
DR2 [018],
DR16 [06]a
DR15 [8291],
DR2 [59],
DR16 [09]a
DR16 [31], DR15

[38], DR2 [31]
DR16 [5682],
DR2 [1228],
DR15 [622]a
Assigned type [%]
13
17
31
Cells tested
239
703
1
2
DR15 [100]b
DR15 [100]b
DR15 [100]b
DR16 [41], DR2

[29], DR15 [19]
DR16 [47], DR2
[30], DR15 [16]
286
676
6428
Cells tested
DR15 [100]b
DR15 [77], DR2

[16]
DR15 [81], DR2
[13]
DR15 [76], DR2

[23]
Assigned type [%]
NMDP
DR16
Training DR2 DR16
DR15
DR15
DR2
DR15
DR15
DR2
DR15
DR15
DR15
NT
DR15
DR15
DR15
DR2f
DR15
Training DR2 DR16
DR15
DR15
DR15
DR15
Training DR2 DR15
Training DR2 DR15
DR14
Training DR2 DR15
Assigned type >0.55
NN
NN: DR15, DR16
NN: DR15, DR16
NN: DR15
Comments
163
164
b
c
d
e
f
DR16(2)d
DR16(2)
DR16
DR16
DR16
DR16
DR16
DR16
DRB1*1605
DRB1*1607
DRB1*1608
DRB1*1609
DRB1*1610
DRB1*1611
DR16
DR16
DR16
DR16
DR16
DR16
1
DR16 [100]b
DR16
1
DR16(2)
DRB1*1604
DR16
DR16 [5364],
DR15 [1627],
DR2 [931]a
DR16 [100]b
Assigned type >0.55

Cells tested
Assigned type [%]
Cells tested
Assigned type [%]
WHO assigned
Expert assigned
HLA allele
Table 4 Continued
NMDP
NN
Comments
NMDP database; some individuals carried the allele but did

not have associated serologic typing. In some cases, the
number of cells tested is less than the number in the last
dictionary. In these cases, the typing assignment may have
changed or further data suggest that the typing result was
not informative.
Neural network
An artificial NN was used to predict serologic assignments

for alleles lacking this information and to support serologic
assignments from other sources (7). The same set of alleles
used in previous iterations was used to train the NN. The
training alleles and the broad and split serologic assignments used in the training are indicated in the tables. In this
2008 report, 10 NN were run instead of the five previously
run to increase accuracy of the predictions. After training of
10 independent NN for each locus, the NN were used to
predict the serologic types associated with polymorphic
amino acid sequences of the remaining allelic products and
results summarized from the 10 networks. Primary assignments are listed in one column, secondary assignments in the
Comments column. The criteria used for inclusion are
described in the 2004 dictionary. Some allelic products with
unusual combinations of serologic epitopes did not receive
an assignment from the NN or have received varying
assignments in the different published iterations of the
network analysis. For example, A*0255, an allele evaluated
in all three iterations of the NN received varying assignments from the NN. In the first NN (7), A2 was assigned as
the primary specificity with A28 and A69 as secondary
specificities; in the second NN (4), A28 was primary with
A69 as secondary; and in this iteration summarizing 10 NN,
no specificity was assigned (serologic blank) and A2, A69,
and A28 were assigned as secondary specificities.
It should be noted that a few cases were observed where
the NN did not assign the same serologic specificity as
expected based on the validation data set. For example,
B*1529 was assigned as B71 by the NN when previously this
allele had been assigned as B15 by serology. This
discrepancy could be because of limited serologic typing
data or because of limitations of the NN prediction. The
data from the NN can be viewed at http://bioinformatics.
nmdp.org/neuralnetwork2007.
The use of a NN to predict the serologic assignments of
antigens encoded by the HLA-C and -DQB1 loci is new. The
alleles with well-defined serology used to train the NN and
to validate the network assignments are indicated in
Tables 3 and 6.
Serology allele phenotype component of the 13th
International Histocompatibility Workshop
The data from the 13th IHWG were obtained by serologic

typing of cells with known HLA alleles. The cells were
DRB3*0204
DRB3*0205
DRB3*0206
DRB3*0207
DRB3*0208
DRB3*0209
DRB3*0210
DRB3*0211
DR52
DR52
DR52
DR52
DR52
DR52
DR52
DR52
DR52
DRB5*0111
DRB5*0112
DRB5*0113
DRB5*0202
DRB5*0203
DRB5*0204
DRB5*0205
DRB5*0109
DRB5*0110N
DRB5*0101
DRB5*0102
DRB5*0103
DRB5*0104
DRB5*0105
DRB5*0106
DRB5*0107
DRB5*0108N
DRB4*0104
DRB4*0105
DRB4*0106
DRB4*0107
DRB4*0201N
DRB4*0301N
DRB3*0222
DRB3*0301
DRB3*0302
DRB3*0303
DRB4*0101
DRB4*0102
DRB4*0103
DRB4*01030102N
DR51
DR51
DR51
Null
DR53
Null
Null
DR52
DR52
DR53
DR53
Null
Undefined
Undefined
Undefined
DR51
Undefined
Undefined
Undefined
DR51
41
10
DR51 [82100]a
DR51 [86100]a
Refer to commentsa
DR51 [86100]a
15
Refer to commentsa 1
41
1
44
73
23
Refer to comments
DR52 [90100]a
DR52 [100]a
DR53 [94100]a
DR53 [88100]a
Refer to comments
DR51 (55), false-positive

assignments
DR51 (4360), falsepositive assignments
DR53 (69) false-positive

assignments
DR53 (2054), falsepositive assignments

WHO
assigned Assigned type [%]
Cells tested Comments
Undefined
Not expressed Null
DR51
DR51
Undefined
Undefined
Undefined
Undefined
DR51
Not expressed
Undefined
DR53
Undefined
Undefined
Not expressed
Not expressed
Undefined
DR52
DR52
DR52
DR53
Undefined
DR53
Not expressed
Expert
assigned
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
Undefined
3
126
1
DR52 [97100]a
DR52 [90100]
DR52 [100]
DR52 [91]a
88
1
DR52 [90100]a
DR52 [99]
Undefined
Undefined
DR52
DR52
DR52
DR52
DR52
DR52
DRB3*0109
DRB3*0110
DRB3*0111
DRB3*0201
DRB3*0202
DRB3*0203
DR52
DR52
DR52
DRB3*0214
DRB3*0215
DRB3*0216
DRB3*0217
DRB3*0218
DRB3*0219
DRB3*0220
DRB3*0221
Undefined
DR52
Undefined
DR52
DR52
DR52
DRB3*0101
DRB3*0102
DRB3*0103
DRB3*0104
DRB3*0105
DRB3*0106
DRB3*0107
DRB3*0108
DR52
DR52
Undefined
Undefined
Undefined
DR52
DR52
Undefined
HLA allele

WHO
assigned Assigned type [%]
Cells tested Comments HLA allele
DRB3*0212 Undefined
DRB3*0213 Undefined
Expert
assigned
Table 5 HLA-DRB3, DRB4, DRB5 alleles and their serologic designations
165
Table 6 HLA-DQB1 alleles and their serologic designations

International Cell Exchange,
UCLA
HLA allele
Expert
assigned
WHO
assigned
DQB1*0201
DQB1*0202
DQB1*0203
DQB1*0204
DQB1*0205
DQB1*0301
DQ2
DQ2
DQ2
DQ2
DQ2
DQ7
DQ2
DQ2
DQ2
DQ7(3)
DQB1*0302
DQ8
DQ8(3)
DQB1*0303
DQ9
DQ9(3)
DQB1*0304
DQ7
DQ7(3)
DQB1*0305
DQ8
DQB1*0306
DQB1*0307
DQB1*0308
DQB1*0309
DQB1*0310
DQB1*0311
DQB1*0312
DQB1*0313
DQB1*0314
DQB1*0315
DQB1*0316
DQB1*0317
DQB1*0318
DQB1*0319
DQB1*0320
DQB1*0401
Assigned type [%]

a
Cells
tested
DQ8(3)c
DQ2 [87100]
DQ2 [75100]a
DQ7 [4791], DQ3

[944], DQ8
[012]a
DQ3 [960], DQ8
[2491], DQ7
[020], DQ9
[09]a
DQ3 [2260], DQ9
[2067], DQ7
[011], DQ8
[09]a
DQ7 [60], DQ3
[34]
DQ3
DQ8
DQ8
DQ7
DQ3
DQ8
DQ9
DQ7
DQ3
DQ9
DQ7
DQ9
DQ8
DQ7
DQ9
DQ4
DQ3
DQ8(3)
DQ4
DQ7 [91], DQ3 [9]a
DQ4 [8889]a
DQB1*0402
DQ4
DQ4
DQ4 [77100]a
22
DQB1*0501
DQ5
DQ5(1)
27
DQB1*0502
DQ5
DQ5(1)
DQB1*0503
DQ5
DQ5(1)
DQB1*0504
DQ5
DQ5(1)c
DQB1*0505
DQB1*0601
DQ5
DQ6
DQ6(1)
DQ1 [2567], DQ5

[2063], DQ6
[013]a
DQ1 [4470], DQ5
[1038], DQ6
[937]a
DQ1 [6489], DQ5
[918], DQ6
[027]a
DQ1 [66], DQ5
[23], DQ6 [8]
DQ6 [5056], DQ1

[3340], DQ5
[1011]a
166
NMDP
Assigned type [%]
NN
Cells
tested
Assigned
type >0.55
30
23
71
DQ2 [98]
DQ2 [87]
DQ2 [67]b
DQ7 [85], DQ3

[10], DQ8 [1]
9175
656
3
12,220
Training DQ2
DQ2
DQ2
DQ2
DQ2
Training DQ3 DQ7
37
DQ8 [66], DQ3

[25], DQ7 [4]
6687
Training DQ3 DQ8
23
DQ9 [67], DQ3

[12], DQ2 [11],
DQ8 [1], DQ7
[1]
DQ7 [40], DQ3
[35], DQ8 [8]
DQ8 [34], DQ3
[30]
DQ8 [100]b
DQ7 [100]b
DQ4 [71], DQ3

[10]
DQ4 [86], DQ3 [2],
blank [7]
DQ5 [69], DQ1
[20], DQ6 [2]
2653
Training DQ3 DQ9
111
DQ7
70
DQ8
142
DQ4
DQ8
DQ8
DQ7
DQ7
DQ8
DQ9
DQ7
DQ3d
DQ9
DQ7
DQ9
DQ8
DQ7
DQ9
DQ4
1085
Training DQ4
5539
Training DQ1 DQ5
20
DQ5 [48], DQ1

[24], DQ6 [15]
919
DQ5
17
DQ5 [58], DQ1

[22], DQ6 [4]
1327
DQ5
DQ5 [58], DQ1

[17], DQ6 [2]
DQ6 [64], DQ1

[23]
48
DQ5
675
DQ5
DQ6
Comments
NN: DQ7, DQ8
Table 6 Continued
International Cell Exchange,
UCLA
HLA allele
Expert
assigned
WHO
assigned
DQB1*0602
DQ6
DQ6(1)
DQB1*0603
DQ6
DQ6(1)
DQB1*0604
DQ6
DQ6(1)
DQB1*0605
DQ6
DQB1*0606
DQB1*0607
Assigned type [%]
Cells
tested
NMDP
Assigned type [%]
NN
Cells
tested
Assigned
type >0.55
22
DQ6 [67], DQ1

[30], DQ5 [1]
5151
Training DQ1 DQ6
18
DQ6 [62], DQ1

[23], DQ5 [2]
2807
DQ6
DQ6 [59], DQ1

[27], DQ5 [2]
1592
DQ6
DQ6(1)
DQ1 [3873], DQ6

[1864], DQ5
[012]a
DQ1 [3164], DQ6
[2263], DQ5
[010]a
DQ1 [4052], DQ6
[4044], DQ5
[020]a
358
DQ6
DQ5
DQ6
1
4
DQ5
DQ6
DQB1*0608
DQ6
DQ6(1)c
DQ6
DQB1*0609
DQ6
DQ6(1)
149
DQ6
DQB1*0610
DQB1*0611
DQB1*0612
DQB1*0613
DQB1*0614
DQB1*0615
DQB1*0616
DQ1
DQ1
DQ1
DQ6
DQ6
DQ6
DQ6
DQ1
DQ1
DQ6(1)
DQ1 [100]b
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQB1*0617
DQB1*0618
DQB1*0619
DQB1*0620
DQB1*0621
DQB1*0622
DQB1*0623
DQB1*0624
DQB1*0625
DQB1*0626N
DQB1*0627
DQB1*0628
DQB1*0629
DQB1*0630
DQB1*0631
DQB1*0632
DQB1*0633
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
Not expressed
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6(1)
Null
DQ6 [3867], DQ1

[2744], DQ5
[06]a
DQ6 [3356], DQ1

[3256], DQ5
[611]a
DQ6 [76], DQ1

[13]
DQ5 [100]b
DQ1 [75], DQ6
[25]b
DQ6 [50], DQ1
[25], DQ5 [25]b
DQ6 [48], DQ1
[32], DQ5 [3]
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
NT
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
DQ6
be
be
Comments
DQ6
b
Updated NMDP data. In some cases, the information reported in previous dictionaries has changed. Cells have been excluded from this study in some
cases because their HLA typing has changed.
c
d
e
a
167
tested with a common set of well-characterized reagents

including mainly monoclonal antibodies (12) and supplementary allosera. Tables 13 show the number of panel
cells for each allele included in the analysis, the assigned
specificity and, where appropriate, comments on the serological expression of that allele, as reported by the 13th
IHWS serology and HLA phenotype component (8, 9).
These data have not been updated from the 2004 edition of
the HLA data dictionary.
Information obtained from other sources
Data on the serological expression of new alleles have been

submitted from HLA laboratories. However, because many
laboratories no longer perform serological typing or use
commercial monoclonal reagents, there are only a small
number of alleles that have been tested in this way. In this
edition of the dictionary, only 23 HLA class I alleles have
been submitted with serological information. The Comments column in the tables refers to information from
publications (listed at end of document) and other sources
that describe serologic expression of new alleles. It must be
noted, however, that some of these data are based on small
sample numbers tested by a single laboratory.
Some alleles in the tables are listed with more than one
common serological assignment. This indicates that the
serological pattern is not clear, for example B*4416 has both
B47 and B44 reactivity. The Comments section may
provide further information for serological reactivity in
some cases. In addition, many laboratories are not able to
identify many of the WHO-designated HLA specificities.
The International Cell Exchange, UCLA data show that
some of the newer specificities are rarely used but are often
designated by their antigen equivalents, for example A2
instead of A203. Although subsequent cell exchanges do
improve the detection rate, these assignments remain
difficult. It is useful to refer to the percentage recognition information when selecting alternative antigens for
alternative searches.
Searchable links between alleles and serologic
assignments
A searchable form of the dictionary is available through the

IMGT/HLA database (5) at http://www.ebi.ac.uk/imgt/
hla/. This information can then be used by HSC registries to
routinely update their matching algorithms and to support
other search and matching activities.
Expert assigned type
Acknowledgments
The expert assigned type for HLA-A, -B, -C, -DRB1, -DRB
3/4/5, and -DQB1 alleles is the combination of all serologic
equivalents information. This may help identify serologic
equivalents when there are differences with the WHO HLAdesignated serologic assignments (e.g. B*4005), or where
multiple assignments are possible such as hybrid molecules,
or where more antigen assignments are given (e.g. A* 3204,
Table 1 and B*1303, B*1304, Table 2). Occasionally, the
expert assigned type is based on the NN assignment;
however, while this should be considered with caution, the
NN may be the only information available.
This work was supported in part by the US Office of Naval

Research N00014-05-1-0859 to the NMDP (MS, MM, and
JK) and N00014-06-1-0726 to the C.W. Bill Young Marrow
Donor Recruitment and Research Program (CKH). The
participants of the International Cell Exchange, UCLA and
the Transplantation and Immunogenetics Laboratory of
the Welsh Transfusion Service are acknowledged for their
contribution.
Use of the dictionary in a HSC donor search
The HLA dictionary is a valuable tool in the search for

a matched unrelated stem cell source for a patient in need. It
contains the most current data, from multiple sources, on
the frequency of the phenotype detected for a particular
allele. An alternate patient phenotype can be identified to
assist with serologic types that may be potential matches for
a particular allele, for example B*4807 types as B48 (33%)
and B60 (42%). The search report for a patient with B*4807
will include B48-positive donors, but an alternate phenotype search using B60 would identify serologically typed
B60 donors with potential to match. In addition, some
alleles routinely type as blank by serology. The dictionary
can help determine whether donors with serologic blanks
(apparent homozygotes) carry the allele of interest.
168
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169
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170
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Tissue Antigens ISSN 0001-2815

The HLA dictionary 2008: a summary of HLA-A, -B, -C, -DRB1/3/

The 2008 edition of the human leukocyte antigen (HLA)

defined alleles can be used to identify potential donors listed

HLA alleles and serologic types

(NMDP) in the United States, the percent of serologic

WHO nomenclature: allele and serologic

The 2008 edition of the dictionary contains all alleles from

The International Cell Exchange, UCLA provided data

Assigned type [%]

Table 1 HLA-A alleles and their serologic designationsg

The allele was used

Assigned type [%]

A2 [67], blank [33]c

HLA alleles and serologic types

Assigned type [%]

NN: A2, A28, A69

A2x9, few A23 1 24

Assigned type [%]

NN: A69, A28

HLA alleles and serologic types

Assigned type [%]

A3 sera negative, only

ihw13: only reactive

Assigned type [%]

Short A11; normal

ihw13: short A11

HLA alleles and serologic types

A24 [6668], A2403

Assigned type [%]

A24 [62], blank [25],

A24 [97], A2403 [1]

A24 [55], blank [20],

A23 [95], A24 [1]

ihw13: short A23,

A23 [6770], A24

Assigned type [%]

A24 [50], A9 [50]c

A24 [67], blank [33]c

A24 [45], A23 [50]

ihw13: short A24

A9variant; A24 sera

ihw13: short A24

A2403; ihw13: short

Short A24, similar to

HLA alleles and serologic types

Assigned type [%]

Assigned type [%]

A26 [75], A34 [25]c

A26 [33], A10 [33],

A25 [95], A10 [2]

A26 [97], A10 [2]

ihw13: only few A10

Short A26, A10

NN: A43, A10, A26

ihw13: short A26

HLA alleles and serologic types

Assigned type [%]

NN: A32, A29

Assigned type [%]

A31 [90], A30 [3],

A30 [89], A31 [3],

NN: A32, A23, A9

ihw13: very short