NTU Supervisors (School of Biological Sciences) - Updated in Feb 2012

Supervisor Appointment Email Contact Research areas of potential PhD studies

Division of Structural Biology and Biochemistry Bhattacharyya Surajit Cornvik, Tobias Carl Davey, Curt Alexander Asst/Prof Asst/Prof Asst/Prof Surajit@ntu.edu.sg TCCornvik@ntu.edu.sg Davey@ntu.edu.sg

Nuclear Magnetic Resonance Studies of Proteins and Protein-Protein Complexes. Engineering and screening methods for directed evolution of proteins Structural biology of chromatin, gene regulation, and genetic recombination, X-ray crystallographic and mechanistic studies of protein-DNA assemblies, Characterization and design of anti-cancer and generegulating agents for targeting genomic DNA, Characterization and design of anti-cancer and generegulating agents for targeting genomic DNA Biochemical and biophysical investigation of structure and function of membrane proteins involved in cell signalling and solute homeostasis Structure and function of macromolecule, structure-based drug design targeting ribosome Characterization of biomolecular interactions using Surface Plasmon Resonance Biosensors. Structure and function of molecular motors and sensors. Tuberculosis, Malaria Molecular and Structural Virology Biochemistry and Chemical biology Pharmaceutical biotechnology Computational biology and molecular modeling Biological and Bioinspired Materials, Protein Chemistry, Biophysics of structural proteins, Protein engineering of high-performance fibers and materials, NextGen Sequencing of Biological Materials, Nanomechanics, Marine invertebrates biology Protein, peptide folding, drug-target interaction, DNA-protein interaction Compaction of DNA protein-protein complexes by NMR in solutions

Eshaghi Said Gao Yonggui Geifman Shochat, Susana Gruber, Gerhard Lescar, Julien Liang Zhao-Xun Liu Chuan Fa Lu Lan Yuan Miserez, Ali

A/Prof

said.eshaghi@ntu.edu.sg

Nanyang A/Prof ygao@ntu.edu.sg A/Prof Prof A/Prof Asst/Prof A/Prof Asst/Prof Nanyang Asst/Prof Asst/Prof Prof A/Prof SGeifman@ntu.edu.sg GGrueber@ntu.edu.sg Julien@ntu.edu.sg ZXLiang@ntu.edu.sg CFLiu@ntu.edu.sg LYLU@ntu.edu.sg ali.miserez@ntu.edu.sg

Mu Yuguang Nordenskiold, Lars Pervushin, Konstantin

YGMu@ntu.edu.sg LarsNor@ntu.edu.sg kpervushin@ntu.edu.sg

NTU Supervisors (School of Biological Sciences) - Updated in Feb 2012

Supervisor Rhodes, Daniela Appointment Prof Email Contact DRhodes@ntu.edu.sg Research areas of potential PhD studies

Chromatin and Telomere Structure. The research of my group focusses on two areas of chromosome biology: the structure and function of chromatin and telomeres. In the area of chromatin, research will focus on the determination of the 3D structure of the 30nm chromatin fibre using cryo-EM methods and how structural proteins such as the linker histone and histone epigenetic marks regulate its compaction. This work should provide essential insights into all biological processes whose substrate is DNA. In the area of telomere biology the 3D structure of human telomerase will analysed using a combination of cryo-EM methods and X-ray crystallography as well as investigating telomerase recruitment to telomeres. Such knowledge is needed to progress in our understanding of the molecular mechanisms of cancer propagation and human ageing. Mass Spectrometry, Proteomics Study of Cancer, Cardiovascular and Cerebral Ischemia/Reperfusion
Design and Engineering of Antiviral Therapeutics, Plant Biologics and Immunologics

Sze Siu Kwan, Newman Tam, James Tang Kai Torres, Jaume Yoon Ho Sup, Joe

Asst/Prof Prof Asst/Prof A/Prof A/Prof

sksze@ntu.edu.sg JPTam@ntu.edu.sg Tkai@ntu.edu.sg jtorres@ntu.edu.sg HSYoon@ntu.edu.sg

Proteomics, Mass Spectrometry instrumentation Structural and molecular biology of small membrane proteins Apoptosis; Molecular chaperones in cancer and neurodegenerative diseases; NMR; Structure-based drug design Human malaria, antimalarial drug development Protein kinases in pro-inflammatory pathways Molecular and biochemical genetics Transcriptional control of Hox gene expression; Structure and function of homeodomain-containing proteins such as PBX MEIS and PREP Cell death and differentiation Stem cells and regenerative medicine T cell development, haematopietic stem cells Host response to experimental urinary tract infection Signal transduction, signaling in stem cells and cancer cells

Division of Molecular Genetics and Cell Biology Bozdech, Zbynek Cheung Ching For, Peter Droge, Peter Featherstone, Mark Stephen Feng Zhiwei Kambadur, Ravi Karjalainen, Klaus Kline, Kimberly Ann Koh Cheng Gee A/Prof Asst/Prof A/Prof Prof A/Prof A/Prof Prof Nanyang Asst/Prof Asst/Prof ZBozdech@ntu.edu.sg PCFCheung@ntu.edu.sg PDroge@ntu.edu.sg MSFeatherstone@ntu.edu.sg ZWFeng@ntu.edu.sg KRavi@ntu.edu.sg Klaus@ntu.edu.sg KKline@ntu.edu.sg CGKoh@ntu.edu.sg

NTU Supervisors (School of Biological Sciences) - Updated in Feb 2012

Supervisor Kraut, Rachel Susan Law Sai Kit, Alex Li Hoi Yeung Lin Chun Ling, Valerie Liu Ding Xiang Lu Lei Makeyev, Eugene Preiser, Peter Rainer Roca, Xavier Ruedl, Christiane Su I-Hsin Sugrue, Richard Sze Chun Chau Tan Nguan Soon, Andrew Tan Suet Mien Appointment A/Prof Prof A/Prof A/Prof A/Prof Asst/Prof Nanyang Asst/Prof Prof Asst/Prof A/Prof Asst/Prof A/Prof Asst/Prof Asst/Prof A/Prof Email Contact RSKraut@ntu.edu.sg alaw@ntu.edu.sg HYLi@ntu.edu.sg CLLin@ntu.edu.sg DXLiu@ntu.edu.sg LULEI@ntu.edu.sg makeyev@ntu.edu.sg PRPreiser@ntu.edu.sg xroca@ntu.edu.sg Ruedl@ntu.edu.sg IHSu@ntu.edu.sg RJSugrue@ntu.edu.sg CCSze@ntu.edu.sg NSTan@ntu.edu.sg SMTan@ntu.edu.sg Research areas of potential PhD studies

Sphingolipid metabolism and dynamics in membranes and cells, and roles in neurodegeneration Integrin Protein Chemistry Mitotic spindle assembly and disassembly Functional interaction between oestrogen receptor and progesterone receptor Molecular Virology and Viral Pathogenesisn Membrane biology Posttranscriptional control of gene expression; Cell differentiation; Nervous system development Malaria, Invasion of host cell, antigenic variation, multigene families Pre-mRNA splicing and human genetic diseases Immunology and dendritic cells Molecular immunology, Protein lysine methylation virus host interactions, host response to infection, Paramyxoviruses (RSV and HMPV) and human and avian influenza viruses Bacterial interspecies interaction, biofilm, bioremediation, environmental biotechnology Wound Repair, Cancer Biology, Metabolic Syndrome Molecular mechanism and regulation of cell adhesion in hemostasis, immune system, and cancer Wiskott Aldrich Syndrome and Actin cytoskeleton Behavioral manipulation of hosts by parasites Autophagy in neurodegeneration and ageing Epigenetic controls of gene silencing

Thanabalu, Thirumaran Vyas Ajai Wong Siew Peng Esther Zhang Lifeng

A/Prof Nanyang Asst/Prof Asst/Prof Asst/Prof

Thirumaran@ntu.edu.sg AVYAS@ntu.edu.sg EstherWong@ntu.edu.sg ZHANGLF@ntu.edu.sg