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1: Anticancer Res. 1993 Mar-Apr;13(2):475-80.

Cytotoxic effect of ascorbate and its derivatives on cultured malignant and nonmalignant Related Articles
cell lines.
Leung PY, Miyashita K, Young M, Tsao CS.
Linus Pauling Institute of Science and Medicine, Palo Alto, CA 94306.
Altered production of the active oxygen species is involved in
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lines has been examined. L-Ascorbate and its oxidative product dehydroascorbate were cytotoxic
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Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium
potency and very high turnover rate, had similar activities. The cytotoxic effect of ascorbate was Review Ascorbate on cell growth and differentiation.
apparently not related to the metabolic or vitamin activities of ascorbate at the cellular level. [JBioenerg Biomembr.1994]
Furthermore, studies on the viability of treated cells indicated that the observed effect on cell
growth was not cytostatic in nature but was the result of a direct cell-killing action of ascorbate. » See Reviews... | » See All...
Several groups of ascorbate derivatives were also tested; many of them were toxic to these
cells. The results support the hypothesis that the cytotoxic activity of ascorbate was due to its Cited by PubMed Central articles
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PMID: 8517665 [PubMed - indexed for MEDLINE]
Intravenously administered vitamin C as cancer therapy: three
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[Proc
cancer cells: action as a pro-drug to deliver NatlAcadperoxide
hydrogen SciU S A.2
to005]

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Patient Drug Information

Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...)

Ascorbic acid is used to prevent and treat scurvy, a disease
caused by a lack of vitamin C in the body.

Source: AHFS Consumer Medication Information

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