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Psychotic disorders due to a known medical illness or substance use are collectively termed secondary psychoses. This paper reviews the historic evolution of the concept of secondary versus primary psychosis. Careful studies of secondary psychotic disorders can help elucidate the pathophysiology of primary, or idiopathic, psychotic disorders such as schizophrenia.
Psychotic disorders due to a known medical illness or substance use are collectively termed secondary psychoses. This paper reviews the historic evolution of the concept of secondary versus …