Name Of Drug Generic (Brand) Celecoxib

Date Ordered

Classifica tion

Date Frequency Route 200mg/cap BID PO

Mechanism Of Action

Specific Indicatio n To relief joint pain and inflamma tory response with improved mobility.

Side Effects

Nursing Implications

11/27/12

Nonsteroi dal antiinflammat ory drug

Inhibits prostaglandin synthesis primarily by inhibiting cyclooxygenase2 (COX-2); it does not inhibit the cyclooxygenase1 (COX-1) isoenzyme. Does not affect platelet aggregating renal effects similar to other NSAIDS. Cause fewer GI complications, such as bleeding and perforation, compared with other NSAIDS. Metabolized in the liver to

Contrain dication: Should not be given to patients with allergic reactions to sulfanam ides.

GI: BEFORE: Dyspepsia, May take diarrhea, abdominal with food to pain, N&V, dry decrease mouth, flatulence, chance of constipation. GI stomach bleeding, GI upset. hemorrhage, DURING: stomatitis, tooth Seek the disorder lowest dose CNS: for diet. Take Headache, exactly as dizziness, insomia, directed & anorexia, anxiety, same time depression, each day. nervousness, Do not take somnolence, aspirin or hypertonia, aspirin paresthesia, containing vertigo, increased products appetite. without CV: consult of Aggravated HPN, provider. angina pectoris, AFTER: CAD, MI, Avoid palpitations, prolonged

inactivate compounds; excreted in the urine and feces.

tachycardia, thrombocytopenia, CHF-related adverse effects. Respiratory: Sinusitis, pharyngitis, bronchitis, bronchospasm, coughing, dyspnea, laryngitis and pneumonia Derma: Rash, ecchymosis, alopecia, dermatitis, nail disorder and photosensitivity.

exposure to direct or artificial sunlight. Report unusual or persistent side effects including dyspepsia, abdominal pain, dizziness & changes in stool or skin color.

Reference:PDRs DRUG HANDBOOK 2005 Edition

DRUG SUMMARY
Name Of Drug Generic (Brand) Clindamycin Date Ordered Classifi cation Date Frequency Route 300mg/cap TID for 14days PO Mechanism Of Action Specific Indicatio n Serious skin infection & softtissue infections. Side Effects Nursing Implications

11/27/12

Antibiot ic

A semisynthetic antibiotic that suppresses protein synthesis by microrganism by binding to ribosomes (50S subunit) & preventing peptide bond formation. Isboth bacteriostatic & bactericidal.

GI: BEFORE: N&V, diarrhea, Take pseudomembranous medication colitis, abdominal with full pain, esophangitis, glass of unpleasant, or water to mettalic taste, prevent glossitis, stomatitis. esophageal CV: reflux. Contraindi Hypotension, May be cation: Rarely cardiac taken with Hyper arrest after rapid or without sensiti use. food. vity to Allergic: Note any Skin rash, drug history of Urticaria, & liver or lincom erythema, renal anaphylaxis, ycin. disease, maculopapular rash allergies or Hematologic: GI problems Leukopenia, neitropenia, DURING: thrombocytopenia, Monitor trnsient renal & eosinophilia LFTs as Hepatic: ordered. Jaundice AFTER: GU:

Renal dysfunction.

Tell pt to take entire amount prescribed even after he feels better. Observe closely for: Skin rash (frequently reported)

Reference:PDRs DRUG HANDBOOK 2005 Edition

Name Of Date Drug Ordered Generic (Brand) Cefazolin 11/27/12

Classifica tion

Date Frequency Route 1gm IVTT q 8hrs (-)ANST

Mechanism Of Action

Specific Indication

Side Effects

Nursing Implications

Antiinfectives

Bind bacterial cell wall membrane, causing cell death. Active against many grampositive cocci.

Skin structure infections; bone infections.

Contraindicatio n: Hypersensit ivity to cephalosph orins. Serious hypersensit ivity to penicillin.

CNS: Seizure (high doses) GI: Pseudomembranou s colitis, diarrhea, N&V, cramps. GU: Interstisial nephritis Derm: Rashes, urticaria Hema: Blood dyscrasias, hemolytic anemia Local: Pain at IV site, phlebitis at IV site

BEFORE: Obtain a history to determine previous use of reactions to penicillin & cephalosporins. Obtain for culture and sensitivity test before initiating therapy. DURING: Tell patient to report discomfort at IV site. Monitor site for thrombophebitis (pain, redness, swelling) Observe for sign of anaphylaxis (rash, pruritis) AFTER: Instruct pt to notify heath care

provider if fever & diarrhea develop.

Reference:PDRs DRUG HANDBOOK 2005 Edition

Name Of Drug Generic (Brand) Paraceta mol

Date Ordered

Classifi cation

Date Frequency Route 500mg q6H For temp of <38oC

Mechanism Of Action

Specific Indication

Side Effects

Nursing Implications

11/27/12

Antipyr etic

The drug may relieve fever though central action of hypothalamus heat regulating center.

For relief of fever Contraindicatio n: Hypersensiti vity Intolerance to tartrazine (yellow dye #5, alcohol, table sugar, saccharin) Contraindica ted to allergy with acetamoniph en

Hema: Neutropenia, pancytopenia Hepatic: Jaundice Metabolic: Hypoglycemia

BEFORE: Assess temperature <38oC Assess pts pain: type of pain, location, intensity, duration, temperature and diaphoresis. DURING: Recheck pts pain score. AFTER: Assess allergic reactions: rash; if occurs may be discotinued as ordered by the physician.

Reference:PDRs DRUG HANDBOOK 2005 Edition